{"id":"https://openalex.org/W2392849049","doi":null,"title":"The Effectiveness of Adjunctive Systemic Antibiotics to Non Surgical Therapy in Chronic Periodontitis Patients","display_name":"The Effectiveness of Adjunctive Systemic Antibiotics to Non Surgical Therapy in Chronic Periodontitis Patients","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2392849049","mag":"2392849049"},"language":"en","primary_location":{"id":"mag:2392849049","doi":null,"is_oa":false,"landing_page_url":"http://www.jofamericanscience.org/journals/am-sci/am0812/052_12573am0812_374_383.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000803253","display_name":"Riham Omar Ibrahim","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Riham Omar Ibrahim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5060361437","display_name":"Olfat Gamil Shaker","orcid":"https://orcid.org/0000-0002-3031-3599","observed_orcids":["https://orcid.org/0000-0002-3031-3599","https://orcid.org/0009-0008-1421-7338","https://orcid.org/0009-0004-9626-0911"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Olfat Shaker","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3031-3599","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2439,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.55344468,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12439","display_name":"Dental Research and COVID-19","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-periodontitis","display_name":"chronic periodontitis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/moxifloxacin","display_name":"moxifloxacin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/amoxicillin","display_name":"amoxicillin","score":0.7860000133514404},{"id":"https://openalex.org/keywords/metronidazole","display_name":"metronidazole","score":1.0},{"id":"https://openalex.org/keywords/scaling-and-root-planing","display_name":"scaling and root planing","score":0.953000009059906},{"id":"https://openalex.org/keywords/non-surgical-periodontal-therapy","display_name":"non-surgical periodontal therapy","score":0.8899999856948853},{"id":"https://openalex.org/keywords/periodontal-pathogens","display_name":"periodontal pathogens","score":0.7839999794960022},{"id":"https://openalex.org/keywords/periodontal-pocket-reduction","display_name":"periodontal pocket reduction","score":0.6840000152587891},{"id":"https://openalex.org/keywords/periodontal-attachment","display_name":"periodontal attachment","score":0.6809999942779541},{"id":"https://openalex.org/keywords/plaque-index","display_name":"plaque index","score":0.5630000233650208},{"id":"https://openalex.org/keywords/clinical-attachment-loss","display_name":"clinical attachment loss","score":0.609000027179718}],"concepts":[{"id":"https://openalex.org/C2779708577","wikidata":"https://www.wikidata.org/wiki/Q201928","display_name":"Amoxicillin","level":3,"score":0.8319520354270935},{"id":"https://openalex.org/C2777396551","wikidata":"https://www.wikidata.org/wiki/Q169569","display_name":"Metronidazole","level":3,"score":0.8311693072319031},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8295830488204956},{"id":"https://openalex.org/C2779416262","wikidata":"https://www.wikidata.org/wiki/Q15139949","display_name":"Scaling and root planing","level":4,"score":0.8056887984275818},{"id":"https://openalex.org/C2779337755","wikidata":"https://www.wikidata.org/wiki/Q5113988","display_name":"Chronic periodontitis","level":3,"score":0.6784927845001221},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6258577704429626},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.571989119052887},{"id":"https://openalex.org/C2780385504","wikidata":"https://www.wikidata.org/wiki/Q520127","display_name":"Periodontitis","level":2,"score":0.5699758529663086},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.5409916043281555},{"id":"https://openalex.org/C2778836808","wikidata":"https://www.wikidata.org/wiki/Q424940","display_name":"Moxifloxacin","level":3,"score":0.4510827958583832},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.38780105113983154},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0961090624332428},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07191821932792664}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2392849049","doi":null,"is_oa":false,"landing_page_url":"http://www.jofamericanscience.org/journals/am-sci/am0812/052_12573am0812_374_383.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W61223430","https://openalex.org/W1578379614","https://openalex.org/W1931180569","https://openalex.org/W1970179763","https://openalex.org/W1976329656","https://openalex.org/W1977447567","https://openalex.org/W1992456148","https://openalex.org/W1996009278","https://openalex.org/W1998098601","https://openalex.org/W2001181093","https://openalex.org/W2005968340","https://openalex.org/W2016319683","https://openalex.org/W2018441170","https://openalex.org/W2022440427","https://openalex.org/W2034261156","https://openalex.org/W2034349300","https://openalex.org/W2034426744","https://openalex.org/W2038426733","https://openalex.org/W2045264957","https://openalex.org/W2048201917","https://openalex.org/W2053341124","https://openalex.org/W2057364477","https://openalex.org/W2058194052","https://openalex.org/W2065284615","https://openalex.org/W2070115603","https://openalex.org/W2081634694","https://openalex.org/W2081747137","https://openalex.org/W2082284067","https://openalex.org/W2084506086","https://openalex.org/W2085547933","https://openalex.org/W2085665949","https://openalex.org/W2091737060","https://openalex.org/W2092474596","https://openalex.org/W2097553001","https://openalex.org/W2101654981","https://openalex.org/W2107228383","https://openalex.org/W2119764574","https://openalex.org/W2127404391","https://openalex.org/W2131875099","https://openalex.org/W2132697669","https://openalex.org/W2135788291","https://openalex.org/W2144610619","https://openalex.org/W2155008443","https://openalex.org/W2155178900","https://openalex.org/W2156609334","https://openalex.org/W2156801618","https://openalex.org/W2158125149","https://openalex.org/W2160702537","https://openalex.org/W2164052040","https://openalex.org/W2166413002","https://openalex.org/W2174784305"],"related_works":["https://openalex.org/W7136428172","https://openalex.org/W4391583177","https://openalex.org/W6998606195","https://openalex.org/W2408857957","https://openalex.org/W2897929112","https://openalex.org/W2796244909","https://openalex.org/W1907038649","https://openalex.org/W1926431033","https://openalex.org/W2900349726","https://openalex.org/W2909557986"],"abstract_inverted_index":{"Background:":[0],"The":[1,124,239],"aim":[2],"of":[3,14,52,58,108,112,126,184,192,208,241],"this":[4],"study":[5,129,180],"was":[6,151,166],"to":[7,27,34,37,189,197,245],"assess":[8],"the":[9,119,127,132,145,182,193,209,216,220],"clinical":[10,173],"and":[11,17,20,29,33,63,80,90,103,144,175,196,205,222,235],"microbiological":[12],"effects":[13],"moxifloxacin":[15],"(MOX)":[16],"combined":[18],"amoxicillin":[19,87],"metronidazole":[21,89],"(AMX+":[22],"MET)":[23],"as":[24],"an":[25],"adjunct":[26],"scaling":[28],"root":[30,81],"planning":[31,82],"(SRP)":[32,83],"compare":[35],"it":[36],"conventional":[38,226],"mechanical":[39],"periodont":[40],"al":[41],"treatment":[42,134,188],"alone":[43],"in":[44,137,140,249],"patients":[45],"with":[46,86,94],"advanced":[47],"chronic":[48],"periodontitis":[49],"by":[50],"means":[51],"a":[53],"species":[54],"-":[55,259,264],"specific":[56],"sequences":[57],"DNA.":[59],"Methods:":[60],"Clinical":[61],"parameters":[62,174],"subgingival":[64],"bacterial":[65,176],"plaque":[66,203],"sample":[67],"were":[68],"collected":[69],"from":[70],"forty":[71],"two":[72],"subjects":[73],"divided":[74],"into":[75],"three":[76,133],"groups.":[77],"Scali":[78],"ng":[79],"group,":[84],"SRP":[85,93],"plus":[88],"third":[91],"group":[92],"moxifloxacin.":[95],"Data":[96],"obtained":[97],"before":[98],"initial":[99],"therapy,":[100],"at":[101,159],"3":[102],"6":[104],"months":[105],"after":[106,225],"completion":[107],"therapy":[109],"for":[110,201],"evaluation":[111],"four":[113],"different":[114,160],"periodontopathogenic":[115],"speci":[116],"es":[117],"using":[118],"quantitative":[120],"PCR":[121],"technique.":[122],"Results:":[123],"results":[125],"present":[128],"revealed":[130],"that":[131],"modalities":[135],"resulted":[136],"significant":[138,154,168],"reduction":[139,191],"PI,":[141],"GI,":[142],"PD,":[143],"CAL":[146],"over":[147],"time":[148],"although":[149],"there":[150],"n":[152],"o":[153],"difference":[155],"between":[156,172],"grou":[157],"ps":[158],"follow":[161],"up":[162],"periods":[163],".":[164,238,253,267],"There":[165],"statistically":[167],"strong":[169],"positive":[170],"correlation":[171],"count.":[177],"Conclusion:":[178],"This":[179],"confirms":[181],"efficiency":[183],"non":[185],"surgical":[186],"periodontal":[187,194,210],"achieve":[190],"pockets":[195],"ensure":[198],"proper":[199],"conditions":[200],"effective":[202],"control":[204],"stable":[206],"levels":[207],"attachment.":[211],"Antibiotic":[212],"prescribing":[213],"should":[214],"be":[215],"exception":[217],"rather":[218],"than":[219],"rule":[221],"only":[223],"considered":[224],"therapies":[227],"have":[228],"been":[229],"unsuccessful.":[230],"(":[231],"Riham":[232],"Omar":[233],"Ibrahim":[234],"Olfat":[236],"Shaker":[237],"Effectiveness":[240],"Adjunctive":[242],"Systemic":[243],"Antibiotics":[244],"Non":[246],"Surgical":[247],"Therapy":[248],"Chronic":[250],"Periodontitis":[251],"Patients":[252],"J":[254],"Am":[255],"Sci":[256],"2012;8(12):":[257],"374":[258],"383":[260],").":[261],"(ISSN:":[262],"1545":[263],"1003).":[265],"http://www.jofamericanscience.org":[266],"52":[268]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}
