{"id":"https://openalex.org/W2391825773","doi":null,"title":"The Combined Use of Drugs for Treating Peptic Ulcer: A Report of 233 Cases","display_name":"The Combined Use of Drugs for Treating Peptic Ulcer: A Report of 233 Cases","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2391825773","mag":"2391825773"},"language":"en","primary_location":{"id":"mag:2391825773","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-YYDB200204015.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764740766","display_name":"Yiyao daobao","issn_l":"1004-0781","issn":["1004-0781"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4324114472","host_organization_name":"Publishing House of Herald of Medicine","host_organization_lineage":["https://openalex.org/P4324114472"],"host_organization_lineage_names":["Publishing House of Herald of Medicine"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Yiyao daobao","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100351659","display_name":"He Wang","orcid":"https://orcid.org/0000-0002-2053-9439","observed_orcids":["https://orcid.org/0000-0002-2053-9439"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"He Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2053-9439","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5100351659"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11855","display_name":"Gastrointestinal disorders and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peptic-ulcer","display_name":"peptic ulcer","score":1.0},{"id":"https://openalex.org/keywords/helicobacter-pylori","display_name":"Helicobacter pylori","score":0.902999997138977},{"id":"https://openalex.org/keywords/omeprazole","display_name":"omeprazole","score":0.9959999918937683},{"id":"https://openalex.org/keywords/amoxicillin","display_name":"amoxicillin","score":0.9869999885559082},{"id":"https://openalex.org/keywords/metronidazole","display_name":"metronidazole","score":1.0},{"id":"https://openalex.org/keywords/triple-therapy","display_name":"triple therapy","score":0.7509999871253967},{"id":"https://openalex.org/keywords/duodenal-ulcer","display_name":"duodenal ulcer","score":0.9160000085830688},{"id":"https://openalex.org/keywords/gastric-ulcer","display_name":"gastric ulcer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/14c-urea-breath-test","display_name":"14C-urea breath test","score":0.8799999952316284},{"id":"https://openalex.org/keywords/helicobacter-pylori-eradication","display_name":"Helicobacter pylori eradication","score":0.8429999947547913},{"id":"https://openalex.org/keywords/helicobacter-pylori-infection","display_name":"Helicobacter pylori infection","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8730759024620056},{"id":"https://openalex.org/C2777498785","wikidata":"https://www.wikidata.org/wiki/Q422210","display_name":"Omeprazole","level":2,"score":0.8233169317245483},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.7957251071929932},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7528923749923706},{"id":"https://openalex.org/C2780656511","wikidata":"https://www.wikidata.org/wiki/Q172941","display_name":"Peptic ulcer","level":2,"score":0.7229552268981934},{"id":"https://openalex.org/C2777396551","wikidata":"https://www.wikidata.org/wiki/Q169569","display_name":"Metronidazole","level":3,"score":0.5826665759086609},{"id":"https://openalex.org/C2993747882","wikidata":"https://www.wikidata.org/wiki/Q172941","display_name":"Duodenal ulcer","level":2,"score":0.5175253748893738},{"id":"https://openalex.org/C2777445857","wikidata":"https://www.wikidata.org/wiki/Q423037","display_name":"Ranitidine","level":2,"score":0.4160638451576233},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.32249534130096436},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2391825773","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-YYDB200204015.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764740766","display_name":"Yiyao daobao","issn_l":"1004-0781","issn":["1004-0781"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4324114472","host_organization_name":"Publishing House of Herald of Medicine","host_organization_lineage":["https://openalex.org/P4324114472"],"host_organization_lineage_names":["Publishing House of Herald of Medicine"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Yiyao daobao","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2349417845","https://openalex.org/W2356981198","https://openalex.org/W2374184182","https://openalex.org/W2382829517","https://openalex.org/W2367531306","https://openalex.org/W2372983283","https://openalex.org/W2369135074","https://openalex.org/W4299796444","https://openalex.org/W2351798319","https://openalex.org/W2356998053"],"abstract_inverted_index":{"Objective:To":[0],"study":[1],"the":[2,57,61,93,182,194],"effect":[3],"of":[4,7,11,109,122,171,198],"combined":[5,169],"use":[6,170],"drugs":[8,52],"in":[9,22,111,117,137,141],"treatment":[10],"peptic":[12,17,166],"ulcer.":[13,167],"Methods:233":[14],"gastroscopically":[15],"confirmed":[16],"ulcer":[18,26,30],"patients":[19,58,94],"were":[20,53,95,124,156],"included":[21],"this":[23],"study(DU,":[24],"duodenal":[25],"161;":[27],"GU,":[28,131],"gastric":[29],"72,":[31],"malignant":[32],"GU":[33],"was":[34,113,135,144],"excluded":[35],"through":[36],"pathological":[37],"examination)":[38],"and":[39,102,115,128,139,150,153,173,190],"tested":[40],"with":[41,43,47,100,165],"HP(first":[42],"RUT,":[44],"if":[45],"postive":[46,107],"14":[48,103,183],"C":[49,104,184],"UBT).":[50],"Four":[51],"simadtaneously":[54],"administered":[55],"to":[56,60],"according":[59],"following":[62],"regime:":[63],"Delo":[64],"100":[65],"mg,":[66],"four":[67,79],"times":[68,80],"a":[69,74,81,87,162],"day;":[70,75,82],"Omeprazole":[71],"20":[72],"mg,once":[73],"amoxycillin":[76],"0.5":[77],"g,":[78],"metronidaxole":[83],"0.4":[84],"g":[85],",twice":[86],"day,":[88],"for":[89,126,130,178,192],"2":[90],"weeks.":[91],"All":[92],"examined":[96],"4":[97],"weeks":[98],"later":[99],"gastroscope":[101],"UBT.":[105],"Results:The":[106],"rate":[108,121,134],"HP":[110,132,195],"DU":[112,123,127,138,149],"95.7%":[114],"80.6%":[116],"GU.":[118,142,151],"The":[119,168],"curative":[120],"91.3%":[125],"86.1%":[129],"eradication":[133],"93.0%":[136],"91.4%":[140],"There":[143],"no":[145],"significent":[146],"difference(\ue006P\ue0060.05)":[147],"between":[148],"Liver":[152],"renal":[154],"functions":[155],"normal":[157],"after":[158],"treatmnet.":[159],"Conclusion:HP":[160],"has":[161],"close":[163],"relation":[164],"Delo?Omeprazole?amoxycillin":[172],"metronidazole":[174],"is":[175,187],"significantly":[176],"effective":[177],"treating":[179],"PU.":[180,199],"Meanwhile,":[181],"UBT":[185],"examination":[186],"very":[188],"sensitive":[189],"specific":[191],"detecting":[193],"positive":[196],"cases":[197]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}