{"id":"https://openalex.org/W2391546987","doi":null,"title":"Study of Covalent Immobilization of Heparin onto the Surface of Poly(vinyl chloride) for Antithrombogenicity","display_name":"Study of Covalent Immobilization of Heparin onto the Surface of Poly(vinyl chloride) for Antithrombogenicity","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W2391546987","mag":"2391546987"},"language":"en","primary_location":{"id":"mag:2391546987","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTotal-GNGF200401008.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764952358","display_name":"Journal of Functional Polymers","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311927","host_organization_name":"East China University of Science and Technology","host_organization_lineage":["https://openalex.org/P4310311927"],"host_organization_lineage_names":["East China University of Science and Technology"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Functional Polymers","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100400591","display_name":"Lihui Zhang","orcid":"https://orcid.org/0000-0001-8834-6476","observed_orcids":["https://orcid.org/0000-0001-8834-6476"]},"institutions":[{"id":"https://openalex.org/I94310126","display_name":"Shanxi Normal University","ror":"https://ror.org/03zd3ta61","country_code":"CN","type":"education","lineage":["https://openalex.org/I94310126"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lihui Zhang","raw_affiliation_strings":["School of Chemistry and Materials Science,Shanxi Normal University,Xi'an 710062,China)"],"raw_orcid":"https://orcid.org/0000-0001-8834-6476","affiliations":[{"raw_affiliation_string":"School of Chemistry and Materials Science,Shanxi Normal University,Xi'an 710062,China)","institution_ids":["https://openalex.org/I94310126"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100400591"],"corresponding_institution_ids":["https://openalex.org/I94310126"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.32675593,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13171","display_name":"Polymer Science and PVC","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10313","display_name":"Surface Modification and Superhydrophobicity","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heparin","display_name":"heparin","score":0.8009999990463257},{"id":"https://openalex.org/keywords/polyvinyl-chloride","display_name":"polyvinyl chloride","score":0.9860000014305115},{"id":"https://openalex.org/keywords/covalent-immobilization","display_name":"covalent immobilization","score":0.7860000133514404},{"id":"https://openalex.org/keywords/antithrombogenicity","display_name":"antithrombogenicity","score":0.9049999713897705},{"id":"https://openalex.org/keywords/polyethylene-glycol","display_name":"polyethylene glycol","score":0.9480000138282776},{"id":"https://openalex.org/keywords/surface-modification","display_name":"surface modification","score":0.5569999814033508},{"id":"https://openalex.org/keywords/platelet-adhesion","display_name":"platelet adhesion","score":0.9570000171661377},{"id":"https://openalex.org/keywords/coagulation-time","display_name":"clotting time","score":0.7749999761581421},{"id":"https://openalex.org/keywords/biomaterial-surfaces","display_name":"biomaterial surfaces","score":0.47200000286102295}],"concepts":[{"id":"https://openalex.org/C2781460079","wikidata":"https://www.wikidata.org/wiki/Q338869","display_name":"Vinyl chloride","level":4,"score":0.7490861415863037},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6847679615020752},{"id":"https://openalex.org/C6556556","wikidata":"https://www.wikidata.org/wiki/Q899239","display_name":"Contact angle","level":2,"score":0.6265605092048645},{"id":"https://openalex.org/C2777516009","wikidata":"https://www.wikidata.org/wiki/Q194207","display_name":"Ethylene glycol","level":2,"score":0.5779648423194885},{"id":"https://openalex.org/C2776866176","wikidata":"https://www.wikidata.org/wiki/Q146368","display_name":"Polyvinyl chloride","level":2,"score":0.5682288408279419},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.5594837069511414},{"id":"https://openalex.org/C180577832","wikidata":"https://www.wikidata.org/wiki/Q127920","display_name":"Covalent bond","level":2,"score":0.5473976731300354},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.5022618770599365},{"id":"https://openalex.org/C115537861","wikidata":"https://www.wikidata.org/wiki/Q7645993","display_name":"Surface modification","level":2,"score":0.4795677065849304},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.4468638300895691},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.44457656145095825},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.32653942704200745},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2146020531654358},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.14545217156410217},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.13811075687408447},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.11803406476974487},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2391546987","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTotal-GNGF200401008.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764952358","display_name":"Journal of Functional Polymers","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311927","host_organization_name":"East China University of Science and Technology","host_organization_lineage":["https://openalex.org/P4310311927"],"host_organization_lineage_names":["East China University of Science and Technology"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Functional Polymers","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2380382232","https://openalex.org/W2099964471","https://openalex.org/W2050858086","https://openalex.org/W7099028007","https://openalex.org/W2069983241","https://openalex.org/W4388214976","https://openalex.org/W2028303063","https://openalex.org/W2004827906","https://openalex.org/W2091221745","https://openalex.org/W2358191581"],"abstract_inverted_index":{"Poly(ethylene":[0],"glycol)":[1],"(PEG)":[2],"was":[3,40,68,77],"immobilized":[4,70],"onto":[5,71],"the":[6,13,25,93],"surface":[7,43,72],"of":[8,27,31,47,73,95],"Poly(vinyl":[9],"chloride)":[10],"(PVC)":[11],"by":[12,18,37,56,79],"argon":[14],"plasma-induced":[15],"reaction,":[16],"followed":[17],"a":[19],"reaction":[20,36],"with":[21],"heparin":[22,67],"to":[23],"improve":[24],"antithrombogenicity":[26,76,94],"PVC.":[28,74],"The":[29,42,75],"effect":[30],"PEG":[32,53],"concentration":[33],"on":[34],"immobilizing":[35,52],"Ar":[38],"plasma":[39],"investigated.":[41],"properties":[44],"and":[45,50,60,85],"morphologies":[46],"PVC":[48,97],"before":[49],"after":[51],"were":[54],"studied":[55],"XPS,":[57],"ATR-FTIR,":[58],"SEM":[59],"contact":[61],"angle.":[62],"It":[63,89],"is":[64,90,99],"confirmed":[65],"that":[66,92],"covalently":[69],"determined":[78],"clotting":[80],"time":[81],"measurement":[82],"in":[83],"vitro":[84],"platelet":[86],"adhesion":[87],"experiment.":[88],"shown":[91],"modified":[96],"materials":[98],"increased":[100],"greatly.":[101]},"counts_by_year":[],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}