{"id":"https://openalex.org/W2391444115","doi":null,"title":"Inflammasome and its research progress","display_name":"Inflammasome and its research progress","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W2391444115","mag":"2391444115"},"language":"en","primary_location":{"id":"mag:2391444115","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-JSYX200705026.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764352285","display_name":"Junshi Yixue Kexueyuan yuankan","issn_l":"1000-5501","issn":["1000-5501"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Junshi Yixue Kexueyuan yuankan","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050418643","display_name":"Yi Kong","orcid":"https://orcid.org/0000-0001-6209-0046","observed_orcids":["https://orcid.org/0000-0001-6209-0046"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yi Kong","raw_affiliation_strings":["-Rong,FU Ling,XU Jun-Jie,CHEN Wei"],"raw_orcid":"https://orcid.org/0000-0001-6209-0046","affiliations":[{"raw_affiliation_string":"-Rong,FU Ling,XU Jun-Jie,CHEN Wei","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5050418643"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.25562329,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inflammasome","display_name":"inflammasome","score":1.0},{"id":"https://openalex.org/keywords/caspase-1","display_name":"caspase-1","score":0.9539999961853027},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9150000214576721},{"id":"https://openalex.org/keywords/il-18","display_name":"IL-18","score":1.0},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.9129999876022339},{"id":"https://openalex.org/keywords/inflammasome-activation","display_name":"inflammasome activation","score":0.9290000200271606},{"id":"https://openalex.org/keywords/inflammasome-regulation","display_name":"inflammasome regulation","score":0.9269999861717224},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C2777209026","wikidata":"https://www.wikidata.org/wiki/Q412405","display_name":"Inflammasome","level":3,"score":0.9881798028945923},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.7578921914100647},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.6730493903160095},{"id":"https://openalex.org/C139964883","wikidata":"https://www.wikidata.org/wiki/Q14901964","display_name":"Caspase 1","level":4,"score":0.6430292129516602},{"id":"https://openalex.org/C84982370","wikidata":"https://www.wikidata.org/wiki/Q420927","display_name":"Multiprotein complex","level":3,"score":0.6169500350952148},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6029507517814636},{"id":"https://openalex.org/C187831198","wikidata":"https://www.wikidata.org/wiki/Q18034187","display_name":"AIM2","level":4,"score":0.5562905669212341},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.44215917587280273},{"id":"https://openalex.org/C175156509","wikidata":"https://www.wikidata.org/wiki/Q1990218","display_name":"Cleavage (geology)","level":3,"score":0.4262159466743469},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4226400852203369},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3577292263507843},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.346508264541626},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.33254194259643555},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.23343470692634583},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11257633566856384},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C43369102","wikidata":"https://www.wikidata.org/wiki/Q2307625","display_name":"Fracture (geology)","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2391444115","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-JSYX200705026.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764352285","display_name":"Junshi Yixue Kexueyuan yuankan","issn_l":"1000-5501","issn":["1000-5501"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Junshi Yixue Kexueyuan yuankan","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4043000042438507,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2008202400","https://openalex.org/W1987535382","https://openalex.org/W3033829306","https://openalex.org/W2317517455","https://openalex.org/W3043274703","https://openalex.org/W1992359197","https://openalex.org/W2382886602","https://openalex.org/W4414968969","https://openalex.org/W2409645125","https://openalex.org/W2460178156"],"abstract_inverted_index":{"Activation":[0],"of":[1,9,24,37,66],"caspase-1":[2,25],"leads":[3],"to":[4],"the":[5,34],"cleavage":[6],"and":[7,15,44,63],"secretion":[8],"pro-inflammatory":[10],"cytokines":[11],"such":[12],"as":[13,33],"IL-1\u03b2":[14],"IL-18,which":[16],"play":[17],"important":[18],"roles":[19],"in":[20,56],"innate":[21],"immunity.The":[22],"activity":[23],"is":[26],"regulated":[27],"by":[28,50],"a":[29],"multiprotein":[30],"complex":[31],"known":[32],"inflammasome.Several":[35],"kinds":[36],"inflammasomes":[38],"sensing":[39],"different":[40],"stimulations":[41],"from":[42],"microbial":[43],"injury":[45],"cells":[46],"have":[47],"been":[48],"identified":[49],"analyzing":[51],"mice":[52],"that":[53],"are":[54,68],"deficient":[55],"various":[57],"inflammasome":[58,67],"components.In":[59],"this":[60],"paper,the":[61],"components,activation,regulation":[62],"biological":[64],"function":[65],"reviewed.":[69]},"counts_by_year":[],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}