{"id":"https://openalex.org/W2390937384","doi":null,"title":"THE PROTECTIVE EFFECTS OF STREPTOCOCCUS THERMOPHILUS grx02 FERMENTED MILK ON ALCOHOLIC LIVER INJURY IN RATS","display_name":"THE PROTECTIVE EFFECTS OF STREPTOCOCCUS THERMOPHILUS grx02 FERMENTED MILK ON ALCOHOLIC LIVER INJURY IN RATS","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2390937384","mag":"2390937384"},"language":"en","primary_location":{"id":"mag:2390937384","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-YYXX201202020.htm","pdf_url":null,"source":{"id":"https://openalex.org/S4306500430","display_name":"Acta Nutrimenta Sinica","issn_l":"0512-7955","issn":["0512-7955"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Acta Nutrimenta Sinica","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078341083","display_name":"Huijing Wang","orcid":"https://orcid.org/0000-0003-2072-1350","observed_orcids":["https://orcid.org/0000-0003-2072-1350"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Huijing Wang","raw_affiliation_strings":["SUN-Yun1"],"raw_orcid":"https://orcid.org/0000-0003-2072-1350","affiliations":[{"raw_affiliation_string":"SUN-Yun1","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5078341083"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.03420000150799751,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/streptococcus-thermophilus","display_name":"Streptococcus thermophilus","score":0.9120000004768372},{"id":"https://openalex.org/keywords/fermented-milk","display_name":"fermented milk","score":0.9660000205039978},{"id":"https://openalex.org/keywords/alcoholic-liver-injury","display_name":"alcoholic liver injury","score":0.9649999737739563},{"id":"https://openalex.org/keywords/hepatoprotective-effect","display_name":"hepatoprotection","score":0.7419999837875366},{"id":"https://openalex.org/keywords/mitochondrial-lipid-peroxidation","display_name":"mitochondrial lipid peroxidation","score":0.8330000042915344},{"id":"https://openalex.org/keywords/na-k-atpase","display_name":"Na+/K+-ATPase","score":0.9020000100135803},{"id":"https://openalex.org/keywords/ca2-atpase","display_name":"Ca2+-ATPase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.9129999876022339},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.9789999723434448},{"id":"https://openalex.org/keywords/ethanol-induced-liver-damage","display_name":"ethanol-induced liver damage","score":0.6769999861717224},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":0.9940000176429749}],"concepts":[{"id":"https://openalex.org/C2777276588","wikidata":"https://www.wikidata.org/wiki/Q1041276","display_name":"Streptococcus thermophilus","level":4,"score":0.9617918729782104},{"id":"https://openalex.org/C2778401633","wikidata":"https://www.wikidata.org/wiki/Q418661","display_name":"Malondialdehyde","level":3,"score":0.6972095966339111},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.5718730688095093},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5503508448600769},{"id":"https://openalex.org/C2779429693","wikidata":"https://www.wikidata.org/wiki/Q274959","display_name":"Distilled water","level":2,"score":0.5230304002761841},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.48842114210128784},{"id":"https://openalex.org/C2778276568","wikidata":"https://www.wikidata.org/wiki/Q190161","display_name":"Streptococcus","level":3,"score":0.44347190856933594},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.4419502913951874},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.43230539560317993},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3586937189102173},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3355874717235565},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3058319687843323},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2171083688735962},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1641291081905365},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16322141885757446},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.15288224816322327},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.14801663160324097},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.07525554299354553},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2390937384","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-YYXX201202020.htm","pdf_url":null,"source":{"id":"https://openalex.org/S4306500430","display_name":"Acta Nutrimenta Sinica","issn_l":"0512-7955","issn":["0512-7955"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Acta Nutrimenta Sinica","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2357859925","https://openalex.org/W2382241964","https://openalex.org/W2539827661","https://openalex.org/W4287533654","https://openalex.org/W2236982768","https://openalex.org/W7163750335","https://openalex.org/W4387004119","https://openalex.org/W2121303369","https://openalex.org/W2009136252","https://openalex.org/W4317207670"],"abstract_inverted_index":{"Objective":[0],"To":[1],"study":[2],"the":[3,12,94,100,115,158,165,171,194,201,213,230,239],"protection":[4,24],"effects":[5],"of":[6,14,72,96,137,147,150,168,173,178,186,196,203,206,215,232],"lactobacillus":[7],"Streptococcus":[8,189],"thermophilus":[9,161,190,218],"grx02":[10,162,191,219],"on":[11,224],"mitochodria":[13,152,207,236],"alcoholic":[15],"liver":[16,198,226],"injury":[17,227],"in":[18,175,235],"rats":[19,28,126],"and":[20,42,48,132,211,237],"explore":[21],"its":[22],"possible":[23],"mechanism.Method":[25],"Seventy":[26],"Wistar":[27],"were":[29,51,67,103,127,142,153,181],"randomly":[30],"divided":[31],"into":[32],"seven":[33],"groups:control":[34],"group,model":[35],"group,Dongbao":[36],"Gantai":[37,62],"group,grx02":[38,63],"fermented":[39,64,76,90],"milk":[40,65,77,91],"groups(high,middle,low-dose)":[41],"positive":[43,82],"control":[44,46,83,116],"group.The":[45],"group":[47,50,84,102,117,180],"model":[49,159],"gavaged":[52,68,86],"with":[53,69,87,157],"distilled":[54,123],"water":[55],"14":[56,70,92,105,121],"ml/kg":[57,71,106,122],"for":[58,78,129],"6":[59,79],"w.The":[60],"Dongbao":[61,73],"groups":[66,98],"Gantai,108,107,106":[74],"cfu/ml":[75,89],"w":[80],"respectively.The":[81],"was":[85,118],"108":[88],"ml/kg.At":[93],"end":[95],"experiment,all":[97],"except":[99],"conrol":[101],"admimistend":[104],"50%":[107],"ethanol":[108],"at":[109],"1":[110],"hr":[111],"after":[112],"last":[113],"gavage,while":[114],"shill":[119],"given":[120],"water.Then":[124],"all":[125],"fasted":[128],"12":[130],"h":[131],"then":[133],"sacrificed.The":[134],"serum":[135,166],"levels":[136,167],"glutamate":[138],"aminotransferase(ALT),aspartate":[139],"aminotransferase(AST),and":[140],"triglycerides(TG)":[141],"measured,while":[143],"mitochondria":[144],"malondialdehyde(MDA),the":[145],"activity":[146,172,231],"superoxide":[148],"dismutase(SOD),Na+-K+-ATPase,Ca2+-ATPase":[149],"extracted":[151],"also":[154],"determined.Results":[155],"Compared":[156],"group,Streptococcus":[160],"could":[163,192],"decrease":[164],"ALT,AST,TG,and":[169],"increase":[170],"Na+-K+-ATPase,Ca2+-ATPase":[174],"mitochodria(P0.05).Meanwhile,the":[176],"indices":[177],"high-dose":[179],"more":[182],"potent":[183],"than":[184],"those":[185],"other":[187],"groups.Conclusion":[188],"improve":[193],"function":[195],"alcohol-induced":[197,225],"injury,obviously":[199],"suppress":[200],"action":[202],"lipid":[204],"peroxidation":[205],"induced":[208],"by":[209,228],"alcohol":[210],"enhance":[212],"activities":[214],"Na+-K+-ATPase,":[216],"Ca2+-ATPase.Streptococcus":[217],"has":[220],"remarkable":[221],"protective":[222],"effect":[223],"increasing":[229],"ATP-dependent":[233],"enzyme":[234],"reducing":[238],"injury.":[240]},"counts_by_year":[],"updated_date":"2026-07-28T07:46:37.118299","created_date":"2016-06-24T00:00:00"}