{"id":"https://openalex.org/W2390903975","doi":null,"title":"Study on the association between leukocyte telomere length and genetic variants on TERC gene of Guangxi Zhuang longevity population","display_name":"Study on the association between leukocyte telomere length and genetic variants on TERC gene of Guangxi Zhuang longevity population","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2390903975","mag":"2390903975"},"language":"en","primary_location":{"id":"mag:2390903975","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTotal-ZLXZ201507064.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764863165","display_name":"Zhongguo laonianxue zazhi","issn_l":"1005-9202","issn":["1005-9202"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4324001555","host_organization_name":"Chinese Society of Gerontology","host_organization_lineage":["https://openalex.org/P4324001555"],"host_organization_lineage_names":["Chinese Society of Gerontology"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Zhongguo laonianxue zazhi","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100429386","display_name":"Hai Li","orcid":"https://orcid.org/0000-0002-0485-4981","observed_orcids":["https://orcid.org/0000-0002-0485-4981"]},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hai Li","raw_affiliation_strings":["Department of Pathophysiology,Guangxi Medical University"],"raw_orcid":"https://orcid.org/0000-0002-0485-4981","affiliations":[{"raw_affiliation_string":"Department of Pathophysiology,Guangxi Medical University","institution_ids":["https://openalex.org/I160354086"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100429386"],"corresponding_institution_ids":["https://openalex.org/I160354086"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.22079546,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leukocyte-telomere-length","display_name":"leukocyte telomere length","score":0.9700000286102295},{"id":"https://openalex.org/keywords/tert","display_name":"telomerase reverse transcriptase","score":0.9470000267028809},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9139999747276306},{"id":"https://openalex.org/keywords/longevity","display_name":"longevity","score":0.6470000147819519},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C2776759703","wikidata":"https://www.wikidata.org/wiki/Q1066907","display_name":"Longevity","level":2,"score":0.8028782606124878},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7220629453659058},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.6649833917617798},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.5785625576972961},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5335263609886169},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5125470161437988},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.47800102829933167},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.477236270904541},{"id":"https://openalex.org/C177336024","wikidata":"https://www.wikidata.org/wiki/Q14872779","display_name":"Telomere","level":3,"score":0.44931265711784363},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21303150057792664},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1211245059967041},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2390903975","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTotal-ZLXZ201507064.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764863165","display_name":"Zhongguo laonianxue zazhi","issn_l":"1005-9202","issn":["1005-9202"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4324001555","host_organization_name":"Chinese Society of Gerontology","host_organization_lineage":["https://openalex.org/P4324001555"],"host_organization_lineage_names":["Chinese Society of Gerontology"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Zhongguo laonianxue zazhi","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2030864252","https://openalex.org/W2125343151","https://openalex.org/W2911727661","https://openalex.org/W7132310533","https://openalex.org/W7099251252","https://openalex.org/W2038113153","https://openalex.org/W1979833091","https://openalex.org/W2083683598","https://openalex.org/W2054149921","https://openalex.org/W4247139513"],"abstract_inverted_index":{"Objective":[0],"To":[1],"explore":[2],"the":[3,35,65,73,76,99,112,116,151,188],"potential":[4],"relationship":[5],"between":[6,79,98,200],"polymorphism":[7,45,202],"of":[8,22,61,93,142,145,159,162,190],"TERC":[9,23,80,192,201],"and":[10,26,82,96,109,129,136,203],"leukocyte":[11],"telomere":[12],"length(":[13],"LTL)":[14],"in":[15,64,84,155,205],"Guangxi":[16,206],"Zhuang":[17,207],"longevity":[18,38,40,63,208],"population.":[19,209],"Methods":[20],"Genotyping":[21],"SNPs(":[24],"rs12696304,rs16847897":[25,95],"rs3772190)":[27],"were":[28,46,87,102,134],"performed":[29],"with":[30,48,184,187],"Taq":[31],"Man":[32],"MGB":[33],"for":[34],"members":[36],"from":[37],"population(":[39,51],"group,n":[41,53,69],"=":[42,54,70,105,125],"485),and":[43],"their":[44,49],"compared":[47],"offspring":[50,52],"627),and":[55],"controls":[56],"without":[57],"a":[58],"familial":[59],"history":[60],"exceptional":[62],"same":[66,74],"area(":[67],"control":[68,156],"218);":[71],"at":[72],"time":[75],"possible":[77],"association":[78],"genotypes":[81,141,189],"LTL":[83,158,181,204],"three":[85,100,117,143,152,191],"groups":[86,101,118],"evaluated.":[88],"Results(":[89],"1)":[90],"Genotypic":[91],"frequencies":[92,114],"SNP":[94],"rs3772190":[97],"similar(":[103],"P":[104,124],"0.":[106,126,130],"83,0.":[107],"33":[108],"1.":[110],"00,respectively);":[111],"allelic":[113],"among":[115,150],"also":[119],"showed":[120,147,179],"no":[121,148,197],"significant":[122],"difference(":[123],"70,0.":[127],"83":[128],"98,respectively);the":[131],"minor":[132],"alleles":[133],"C,G":[135],"G.(":[137],"2)":[138],"Between":[139],"different":[140],"loci":[144],"TERC,LTL":[146],"difference":[149],"groups;":[153],"but":[154],"group,the":[157],"G":[160],"carriers":[161],"rs3772190(":[163],"GG":[164],"/":[165],"GA)":[166],"was":[167],"significantly":[168,182],"longer":[169],"than":[170],"AA":[171],"genotype":[172],"carriers.(":[173],"3)":[174],"Multiple":[175],"linear":[176],"regression":[177],"analysis":[178],"that":[180],"correlated":[183],"age,but":[185],"not":[186],"loci.":[193],"Conclusions":[194],"There":[195],"is":[196],"obvious":[198],"correlation":[199]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
