{"id":"https://openalex.org/W2390822728","doi":null,"title":"Comparative study of effects of nitrendipine alone and combination of hydrochlorothiazide and nitrendipine on essential hypertension","display_name":"Comparative study of effects of nitrendipine alone and combination of hydrochlorothiazide and nitrendipine on essential hypertension","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W2390822728","mag":"2390822728"},"language":"en","primary_location":{"id":"mag:2390822728","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZXDY200403012.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764930156","display_name":"Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi","issn_l":"1005-8982","issn":["1005-8982"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4361727480","host_organization_name":"Danan University, Ministry of Health","host_organization_lineage":["https://openalex.org/P4361727480"],"host_organization_lineage_names":["Danan University, Ministry of Health"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Xiao Zhen-jun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Xiao Zhen-jun","raw_affiliation_strings":["and YUAN Ke1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"and YUAN Ke1","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.36354309,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/essential-hypertension","display_name":"essential hypertension","score":0.9549999833106995},{"id":"https://openalex.org/keywords/nitrendipine","display_name":"nitrendipine","score":0.996999979019165},{"id":"https://openalex.org/keywords/hydrochlorothiazide","display_name":"hydrochlorothiazide","score":0.9990000128746033},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.9240000247955322},{"id":"https://openalex.org/keywords/calcium-channel-blockers","display_name":"calcium channel blockers","score":0.8399999737739563},{"id":"https://openalex.org/keywords/thiazide-diuretics","display_name":"thiazide diuretics","score":0.9409999847412109},{"id":"https://openalex.org/keywords/low-dose-antihypertensive-therapy","display_name":"low-dose antihypertensive therapy","score":0.7960000038146973}],"concepts":[{"id":"https://openalex.org/C2780548744","wikidata":"https://www.wikidata.org/wiki/Q416584","display_name":"Nitrendipine","level":3,"score":0.9955481290817261},{"id":"https://openalex.org/C2780361556","wikidata":"https://www.wikidata.org/wiki/Q423930","display_name":"Hydrochlorothiazide","level":3,"score":0.9691852331161499},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7974981069564819},{"id":"https://openalex.org/C2777097880","wikidata":"https://www.wikidata.org/wiki/Q988405","display_name":"Essential hypertension","level":3,"score":0.7572879791259766},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4480232000350952},{"id":"https://openalex.org/C2779918671","wikidata":"https://www.wikidata.org/wiki/Q200656","display_name":"Diuretic","level":2,"score":0.41706719994544983},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3106709122657776},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.1626153290271759}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2390822728","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZXDY200403012.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764930156","display_name":"Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi","issn_l":"1005-8982","issn":["1005-8982"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4361727480","host_organization_name":"Danan University, Ministry of Health","host_organization_lineage":["https://openalex.org/P4361727480"],"host_organization_lineage_names":["Danan University, Ministry of Health"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2003945085","https://openalex.org/W2370006508","https://openalex.org/W2393296008","https://openalex.org/W2362880607","https://openalex.org/W2369989667","https://openalex.org/W2381891246","https://openalex.org/W2386248061","https://openalex.org/W2351222789","https://openalex.org/W2366199093","https://openalex.org/W2352393150"],"abstract_inverted_index":{"Objective:To":[0],"compare":[1],"the":[2,33,60,66,69],"effects":[3],"of":[4,9,35],"nitrendipine":[5,12,38,51,93],"alone":[6,52],"with":[7,20],"combination":[8,34],"hydrochlorothiazide":[10,36,91],"and":[11,37,84,92],"in":[13,39,59,68,95],"small":[14,40,96],"dosage":[15,41],"on":[16],"essential":[17,21,88],"hypertension.Methods:60":[18],"cases":[19],"hypertension":[22,89],"were":[23],"divided":[24],"into":[25],"two":[26],"groups":[27],"randomly.":[28],"The":[29,47],"observation":[30,61],"group":[31,49,62,71],"took":[32,50],"every":[42,53],"day":[43,54],"for":[44,55],"six":[45,56],"weeks.":[46],"control":[48,70],"weeks.Results:The":[57],"efficiency":[58,67],"was":[63,72,75],"93.3%.":[64],"And":[65],"70%.":[73],"It":[74],"significantly":[76],"better":[77],"than":[78],"routine":[79],"treatment":[80],"(P0.01).Conclusions:It":[81],"is":[82],"safe":[83],"effective":[85],"to":[86],"treat":[87],"by":[90],"together":[94],"dosage.":[97]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}
