{"id":"https://openalex.org/W2381301792","doi":null,"title":"[The study on the relationship between human papillomavirus infection and pathogenesis of nasal inverted papilloma and its malignant transformation].","display_name":"[The study on the relationship between human papillomavirus infection and pathogenesis of nasal inverted papilloma and its malignant transformation].","publication_year":2010,"publication_date":"2010-03-01","ids":{"openalex":"https://openalex.org/W2381301792","mag":"2381301792","pmid":"https://pubmed.ncbi.nlm.nih.gov/20464987"},"language":"zh","primary_location":{"id":"pmid:20464987","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20464987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery","raw_type":"English Abstract"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071283839","display_name":"Zhenhua Zhong","orcid":"https://orcid.org/0000-0001-7237-3322","observed_orcids":["https://orcid.org/0000-0001-7237-3322"]},"institutions":[{"id":"https://openalex.org/I4210140515","display_name":"First Hospital of China Medical University","ror":"https://ror.org/04wjghj95","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210140515"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenhua Zhong","raw_affiliation_strings":["Department of Otorhinolaryngology-Head and Neck Surgery, the First Affiliated Hospital of China Medical University, Shenyang, 110001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology-Head and Neck Surgery, the First Affiliated Hospital of China Medical University, Shenyang, 110001, China","institution_ids":["https://openalex.org/I4210140515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048022332","display_name":"Yan AiHui","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aihui Yan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101813017","display_name":"Feifei Jiang","orcid":"https://orcid.org/0000-0002-9583-3982","observed_orcids":["https://orcid.org/0000-0002-9583-3982"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Feifei Jiang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039339617","display_name":"Hongquan Wei","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongquan Wei","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5024419531","display_name":"Xuejun Jiang","orcid":"https://orcid.org/0000-0002-8670-3828","observed_orcids":["https://orcid.org/0000-0002-8670-3828"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xuejun Jiang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0257,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.79429947,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"24","issue":"5","first_page":"209","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":0.5863999724388123,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":0.5863999724388123,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.17190000414848328,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.1662999987602234,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-papillomavirus","display_name":"human papillomavirus","score":0.9580000042915344},{"id":"https://openalex.org/keywords/nasal-inverted-papilloma","display_name":"nasal inverted papilloma","score":0.9929999709129333},{"id":"https://openalex.org/keywords/malignant-transformation","display_name":"malignant transformation","score":0.9100000262260437},{"id":"https://openalex.org/keywords/squamous-cell-carcinoma","display_name":"squamous cell carcinoma","score":0.7889999747276306},{"id":"https://openalex.org/keywords/hpv-16","display_name":"HPV16","score":0.8259999752044678},{"id":"https://openalex.org/keywords/hpv-18","display_name":"HPV 18","score":1.0},{"id":"https://openalex.org/keywords/hpv-11","display_name":"HPV 11","score":0.8999999761581421},{"id":"https://openalex.org/keywords/hpv-6","display_name":"HPV 6","score":0.4339999854564667},{"id":"https://openalex.org/keywords/nasal-polyps","display_name":"nasal polyps","score":0.7590000033378601}],"concepts":[{"id":"https://openalex.org/C2779317333","wikidata":"https://www.wikidata.org/wiki/Q11393885","display_name":"Inverted papilloma","level":3,"score":0.8993870615959167},{"id":"https://openalex.org/C182420344","wikidata":"https://www.wikidata.org/wiki/Q17144130","display_name":"NIP","level":2,"score":0.8030904531478882},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.7489687204360962},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.7102001905441284},{"id":"https://openalex.org/C2778580637","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"HPV infection","level":4,"score":0.6783277988433838},{"id":"https://openalex.org/C31033888","wikidata":"https://www.wikidata.org/wiki/Q752076","display_name":"Malignant transformation","level":2,"score":0.6278983950614929},{"id":"https://openalex.org/C2781390199","wikidata":"https://www.wikidata.org/wiki/Q8055111","display_name":"Nasal polyps","level":2,"score":0.5949548482894897},{"id":"https://openalex.org/C2776350393","wikidata":"https://www.wikidata.org/wiki/Q912796","display_name":"Papilloma","level":2,"score":0.5524614453315735},{"id":"https://openalex.org/C2994532551","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"Human papillomavirus","level":2,"score":0.493309885263443},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4633278250694275},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.4572216868400574},{"id":"https://openalex.org/C2781254715","wikidata":"https://www.wikidata.org/wiki/Q28454687","display_name":"Infection rate","level":2,"score":0.4542837142944336},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42917072772979736},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.41834717988967896},{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.32956576347351074},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32566988468170166},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26778048276901245},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12830790877342224},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.11883261799812317},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.054037392139434814},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009669","descriptor_name":"Nose Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009669","descriptor_name":"Nose Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D018308","descriptor_name":"Papilloma, Inverted","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018308","descriptor_name":"Papilloma, Inverted","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:20464987","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20464987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery","raw_type":"English Abstract"},{"id":"mag:2381301792","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20464987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2354041398","https://openalex.org/W2401134223","https://openalex.org/W2369321681","https://openalex.org/W3031160680","https://openalex.org/W2371204199","https://openalex.org/W4362702899","https://openalex.org/W4404398138","https://openalex.org/W2037066509","https://openalex.org/W2232685225","https://openalex.org/W2392647987"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"investigate":[2],"the":[3,109],"relationship":[4,170],"between":[5,171],"human":[6],"papillomavirus":[7],"(HPV)":[8],"infection":[9,119],"and":[10,17,92,108,113,123,129,176,179],"pathogenesis":[11,162],"of":[12,24,45,60,64,73,83,101,150,155,163,182],"nasal":[13,65,151],"inverted":[14],"papilloma":[15],"(NIP)":[16],"its":[18],"malignant":[19,180],"transformation.":[20],"METHOD:":[21],"Fifty-seven":[22],"cases":[23,59,63,116,149],"NIP":[25,39,76],"were":[26,50,67,104,111],"divided":[27],"into":[28],"2":[29],"groups:":[30],"benign":[31,84],"group,":[32],"squamous":[33],"cell":[34],"carcinoma":[35],"(SCC)":[36],"arising":[37],"in":[38,57,75,147,161],"group":[40,85,103],"(malignancy":[41],"group).":[42],"HPV-DNA":[43,143,156],"types":[44],"6,":[46],"11,":[47],"16,":[48],"18":[49],"detected":[51,146],"by":[52],"polymerase":[53],"chain":[54],"reaction":[55],"(PCR)":[56],"57":[58],"NIP.":[61,164,183],"Thirty":[62],"polyps":[66],"control.":[68],"RESULT:":[69],"Total":[70],"positive":[71,81,99],"rate":[72,82,100],"HPV":[74,124],"was":[77,86,105,144],"64.9%":[78],"(37/57).":[79],"The":[80,98],"60%":[87],"(27/45),":[88],"all":[89],"with":[90,121,127],"single":[91,133,139],"low":[93],"risk":[94,173],"HPV11":[95,128,140],"type":[96,175,178],"infection.":[97,141],"malignancy":[102],"83.3%":[106],"(10/12),":[107],"majority":[110],"HPV16":[112,122,134,174],"HPV18.":[114],"Five":[115],"had":[117,132,138],"double":[118],"(4":[120],"18,":[125],"1":[126],"HPV18),":[130],"four":[131],"infection,":[135],"another":[136],"one":[137],"However,":[142],"not":[145],"any":[148],"polyps.":[152],"CONCLUSION:":[153],"Infection":[154],"has":[157],"an":[158],"important":[159],"effect":[160],"Meanwhile,":[165],"there":[166],"maybe":[167],"a":[168],"close":[169],"high":[172],"HPV18":[177],"transformation":[181]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}