{"id":"https://openalex.org/W2377950359","doi":null,"title":"Electrophysiological and Pathological Changes in C57BL/6J Mice with Age-Related Hearing Loss","display_name":"Electrophysiological and Pathological Changes in C57BL/6J Mice with Age-Related Hearing Loss","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2377950359","mag":"2377950359"},"language":"en","primary_location":{"id":"mag:2377950359","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHER201303031.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764728106","display_name":"Chinese Journal of Otology","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chinese Journal of Otology","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069354984","display_name":"Ren Hong-mia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]},{"id":"https://openalex.org/I4210092099","display_name":"Daping Hospital","ror":"https://ror.org/00fthae95","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210092099"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ren Hong-mia","raw_affiliation_strings":["Department of Otolaryngology Head and Neck Surgery,Key Laboratory of Trauma,Burns and Combined Injury,Institute of Surgery Research,Daping Hospital,the Third Military Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology Head and Neck Surgery,Key Laboratory of Trauma,Burns and Combined Injury,Institute of Surgery Research,Daping Hospital,the Third Military Medical University","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210092099"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5069354984"],"corresponding_institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210092099"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20934358,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10283","display_name":"Hearing Loss and Rehabilitation","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/age-related-hearing-loss","display_name":"age-related hearing loss","score":1.0},{"id":"https://openalex.org/keywords/neuronal-apoptosis","display_name":"neuronal apoptosis","score":0.972000002861023},{"id":"https://openalex.org/keywords/primary-auditory-cortex","display_name":"primary auditory cortex","score":0.9990000128746033},{"id":"https://openalex.org/keywords/auditory-brainstem-response","display_name":"auditory brainstem response","score":0.8289999961853027},{"id":"https://openalex.org/keywords/hearing-threshold","display_name":"hearing threshold","score":0.734000027179718},{"id":"https://openalex.org/keywords/c57bl-6j-mice","display_name":"C57BL/6J mice","score":0.9229999780654907},{"id":"https://openalex.org/keywords/hearing-acuity","display_name":"hearing acuity","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C2780297895","wikidata":"https://www.wikidata.org/wiki/Q18676","display_name":"Auditory cortex","level":2,"score":0.8315044045448303},{"id":"https://openalex.org/C2779912225","wikidata":"https://www.wikidata.org/wiki/Q1756133","display_name":"Presbycusis","level":3,"score":0.7810567617416382},{"id":"https://openalex.org/C551621295","wikidata":"https://www.wikidata.org/wiki/Q182228","display_name":"Brainstem","level":2,"score":0.6900864839553833},{"id":"https://openalex.org/C2780493683","wikidata":"https://www.wikidata.org/wiki/Q16035842","display_name":"Hearing loss","level":2,"score":0.5834430456161499},{"id":"https://openalex.org/C43791021","wikidata":"https://www.wikidata.org/wiki/Q608256","display_name":"Auditory brainstem response","level":3,"score":0.5384845733642578},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.49319881200790405},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.46319693326950073},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.46089309453964233},{"id":"https://openalex.org/C196795494","wikidata":"https://www.wikidata.org/wiki/Q1624817","display_name":"TUNEL assay","level":3,"score":0.43512266874313354},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.42541104555130005},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3861124515533447},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.36608344316482544},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3298724293708801},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2377950359","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHER201303031.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764728106","display_name":"Chinese Journal of Otology","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chinese Journal of Otology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2745734762","https://openalex.org/W3029468813","https://openalex.org/W7098891566","https://openalex.org/W2116421701","https://openalex.org/W2168819411","https://openalex.org/W2389771824","https://openalex.org/W2365744654","https://openalex.org/W3090871521","https://openalex.org/W2807506055","https://openalex.org/W7097869199"],"abstract_inverted_index":{"ObjectiveTo":[0],"investigate":[1],"neuronal":[2],"apoptosis":[3],"in":[4,13,90,105,114,116],"primary":[5,58,92,107],"auditory":[6,11,42,59,93,108],"cortex":[7,60,94,109],"and":[8,24,36,47,62],"changes":[9,40],"of":[10,57,73,87,95,103],"acuity":[12],"C57BL":[14,28,117],"/":[15,29,118],"6J":[16,30,119],"mice":[17,31],"with":[18],"age-related":[19],"hearing":[20,38],"loss(ARHL).MethodsYoung(2":[21],"months":[22,26],"old)":[23,27],"aged(10":[25],"were":[32,51,77],"used":[33,52],"to":[34,53],"detect":[35],"compare":[37,63],"function":[39],"by":[41],"brainstem":[43],"responses.":[44],"HE":[45],"staining":[46],"Tunel-":[48],"POD":[49],"methods":[50],"examine":[54],"the":[55,64,69,74,81,91,100,106],"morphology":[56],"neurons":[61,89,104],"apoptotic":[65,88],"rates":[66],"be":[67],"tween":[68],"two":[70],"groups.ResultsHearing":[71],"thresholds":[72],"aged":[75,96],"group":[76,97],"significantly":[78],"elevated":[79],"than":[80,99],"young":[82,101],"group.":[83],"The":[84],"num":[85],"ber":[86],"increased":[98],"group.ConclusionApoptosis":[102],"plays":[110],"a":[111],"major":[112],"role":[113],"ARHL":[115],"mice.":[120]},"counts_by_year":[],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}