{"id":"https://openalex.org/W2377286273","doi":null,"title":"Integrated treatment of schizophrenia","display_name":"Integrated treatment of schizophrenia","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2377286273","mag":"2377286273"},"language":"en","primary_location":{"id":"pmh:oai:usiena-air.unisi.it:11365/991943","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11365/991943","pdf_url":"http://www.jpsychopathol.it/wp-content/uploads/2015/09/SOPSI_2_15.pdf","source":{"id":"https://openalex.org/S4377196319","display_name":"Use Siena air (University of Siena)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102064193","host_organization_name":"University of Siena","host_organization_lineage":["https://openalex.org/I102064193"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://www.jpsychopathol.it/wp-content/uploads/2015/09/SOPSI_2_15.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112957624","display_name":"A. Carlo Altamura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2803066834","display_name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","ror":"https://ror.org/016zn0y21","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I2803066834","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Carlo Altamura","raw_affiliation_strings":["Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico;","institution_ids":["https://openalex.org/I2803066834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051003442","display_name":"Andrea M. Fagiolini","orcid":"https://orcid.org/0000-0001-5827-0853","observed_orcids":["https://orcid.org/0000-0001-5827-0853"]},"institutions":[{"id":"https://openalex.org/I102064193","display_name":"University of Siena","ror":"https://ror.org/01tevnk56","country_code":"IT","type":"education","lineage":["https://openalex.org/I102064193"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Fagiolini","raw_affiliation_strings":["University of Siena"],"raw_orcid":"https://orcid.org/0000-0001-5827-0853","affiliations":[{"raw_affiliation_string":"University of Siena","institution_ids":["https://openalex.org/I102064193"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032931781","display_name":"Silvana Galderisi","orcid":"https://orcid.org/0000-0002-1592-7656","observed_orcids":["https://orcid.org/0000-0002-1592-7656"]},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Silvana Galderisi","raw_affiliation_strings":["Second University of Naples"],"raw_orcid":"https://orcid.org/0000-0002-1592-7656","affiliations":[{"raw_affiliation_string":"Second University of Naples","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079894838","display_name":"Paola Rocca","orcid":"https://orcid.org/0000-0002-6414-3559","observed_orcids":["https://orcid.org/0000-0002-6414-3559"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paola Rocca","raw_affiliation_strings":["University of Turin"],"raw_orcid":"https://orcid.org/0000-0002-6414-3559","affiliations":[{"raw_affiliation_string":"University of Turin","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100657189","display_name":"Alessandro Rossi","orcid":"https://orcid.org/0000-0001-8723-7622","observed_orcids":["https://orcid.org/0000-0001-8723-7622","https://orcid.org/0000-0002-8496-600X","https://orcid.org/0000-0001-7095-7121","https://orcid.org/0000-0001-7000-5999"]},"institutions":[{"id":"https://openalex.org/I26415053","display_name":"University of L'Aquila","ror":"https://ror.org/01j9p1r26","country_code":"IT","type":"education","lineage":["https://openalex.org/I26415053"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Rossi","raw_affiliation_strings":["University of L'Aquila"],"raw_orcid":"https://orcid.org/0000-0001-8723-7622","affiliations":[{"raw_affiliation_string":"University of L'Aquila","institution_ids":["https://openalex.org/I26415053"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4514,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.67662643,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"21","issue":"2","first_page":"168","last_page":"193"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13944","display_name":"Psychiatric care and mental health services","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12245","display_name":"Counseling, Therapy, and Family Dynamics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.996999979019165},{"id":"https://openalex.org/keywords/integrated-treatment","display_name":"integrated treatment","score":0.847000002861023},{"id":"https://openalex.org/keywords/psychosocial-interventions","display_name":"psychosocial interventions","score":0.843999981880188},{"id":"https://openalex.org/keywords/cognitive-behavioral-therapy","display_name":"cognitive behavioral therapy","score":0.9860000014305115},{"id":"https://openalex.org/keywords/assertive-community-treatment","display_name":"assertive community treatment","score":1.0},{"id":"https://openalex.org/keywords/cognitive-remediation","display_name":"cognitive remediation","score":1.0},{"id":"https://openalex.org/keywords/functional-skills-training","display_name":"functional skills training","score":0.9980000257492065},{"id":"https://openalex.org/keywords/antipsychotic-drugs","display_name":"antipsychotic drugs","score":0.6840000152587891},{"id":"https://openalex.org/keywords/pharmacogenetics","display_name":"pharmacogenetics","score":0.6700000166893005},{"id":"https://openalex.org/keywords/pharmacogenomics","display_name":"pharmacogenomics","score":0.9309999942779541},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.8429999947547913},{"id":"https://openalex.org/keywords/long-acting-injectable-antipsychotics","display_name":"long-acting injectable antipsychotics","score":0.9819999933242798},{"id":"https://openalex.org/keywords/atypical-antipsychotics","display_name":"atypical antipsychotics","score":0.9629999995231628},{"id":"https://openalex.org/keywords/relapse-prevention","display_name":"relapse prevention","score":0.7419999837875366},{"id":"https://openalex.org/keywords/hospitalization-reduction","display_name":"hospitalization reduction","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C150966472","wikidata":"https://www.wikidata.org/wiki/Q3410145","display_name":"Psychosocial","level":2,"score":0.6053814888000488},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.59276282787323},{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.5744404792785645},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.5570950508117676},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.4899072051048279},{"id":"https://openalex.org/C2780494398","wikidata":"https://www.wikidata.org/wiki/Q208144","display_name":"Antipsychotic","level":3,"score":0.4775486886501312},{"id":"https://openalex.org/C2777113529","wikidata":"https://www.wikidata.org/wiki/Q2919171","display_name":"Assertive community treatment","level":4,"score":0.46737661957740784},{"id":"https://openalex.org/C63529061","wikidata":"https://www.wikidata.org/wiki/Q3424681","display_name":"Cognitive remediation therapy","level":3,"score":0.4461438059806824},{"id":"https://openalex.org/C2781265626","wikidata":"https://www.wikidata.org/wiki/Q1147152","display_name":"Cognitive behavioral therapy","level":3,"score":0.41614285111427307},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.39620253443717957},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.3568122982978821},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.33425700664520264},{"id":"https://openalex.org/C2776674806","wikidata":"https://www.wikidata.org/wiki/Q12135","display_name":"Mental illness","level":3,"score":0.22661912441253662},{"id":"https://openalex.org/C134362201","wikidata":"https://www.wikidata.org/wiki/Q317309","display_name":"Mental health","level":2,"score":0.18481537699699402},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.15505847334861755},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.14017820358276367}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:usiena-air.unisi.it:11365/991943","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11365/991943","pdf_url":"http://www.jpsychopathol.it/wp-content/uploads/2015/09/SOPSI_2_15.pdf","source":{"id":"https://openalex.org/S4377196319","display_name":"Use Siena air (University of Siena)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102064193","host_organization_name":"University of Siena","host_organization_lineage":["https://openalex.org/I102064193"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unicampania.it:11591/353698","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11591/353698","pdf_url":null,"source":{"id":"https://openalex.org/S7407055255","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 degli Studi della Campania \"Luigi Vanvitelli\"","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ricerca.univaq.it:11697/133164","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11697/133164","pdf_url":null,"source":{"id":"https://openalex.org/S7407055225","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 degli Studi dell Aquila","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2377286273","doi":null,"is_oa":false,"landing_page_url":"https://www.jpsychopathol.it/wp-content/uploads/2015/09/08_Altamura1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:2801036623","doi":null,"is_oa":false,"landing_page_url":"https://usiena-air.unisi.it/handle/11365/991943","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:usiena-air.unisi.it:11365/991943","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11365/991943","pdf_url":"http://www.jpsychopathol.it/wp-content/uploads/2015/09/SOPSI_2_15.pdf","source":{"id":"https://openalex.org/S4377196319","display_name":"Use Siena air (University of Siena)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102064193","host_organization_name":"University of Siena","host_organization_lineage":["https://openalex.org/I102064193"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2377286273.pdf","grobid_xml":"https://content.openalex.org/works/W2377286273.grobid-xml"},"referenced_works_count":102,"referenced_works":["https://openalex.org/W33991627","https://openalex.org/W109125769","https://openalex.org/W184925537","https://openalex.org/W193561137","https://openalex.org/W1505033123","https://openalex.org/W1514853360","https://openalex.org/W1541013958","https://openalex.org/W1582096759","https://openalex.org/W1863390102","https://openalex.org/W1876385646","https://openalex.org/W1963909307","https://openalex.org/W1963935327","https://openalex.org/W1969636167","https://openalex.org/W1974688396","https://openalex.org/W1979505238","https://openalex.org/W1986011584","https://openalex.org/W1986349579","https://openalex.org/W1988479995","https://openalex.org/W1989794259","https://openalex.org/W1990305577","https://openalex.org/W1995339795","https://openalex.org/W1996088043","https://openalex.org/W1999621050","https://openalex.org/W2001797784","https://openalex.org/W2009583416","https://openalex.org/W2009832071","https://openalex.org/W2010246713","https://openalex.org/W2010425739","https://openalex.org/W2012479321","https://openalex.org/W2013280864","https://openalex.org/W2014026290","https://openalex.org/W2015515732","https://openalex.org/W2020136635","https://openalex.org/W2025729658","https://openalex.org/W2025756001","https://openalex.org/W2029148328","https://openalex.org/W2032041879","https://openalex.org/W2037650878","https://openalex.org/W2041249232","https://openalex.org/W2051218513","https://openalex.org/W2053167033","https://openalex.org/W2056132514","https://openalex.org/W2058819182","https://openalex.org/W2059223794","https://openalex.org/W2060901684","https://openalex.org/W2064284837","https://openalex.org/W2068902942","https://openalex.org/W2070332447","https://openalex.org/W2073442736","https://openalex.org/W2074863161","https://openalex.org/W2076607047","https://openalex.org/W2085126392","https://openalex.org/W2091660180","https://openalex.org/W2092173202","https://openalex.org/W2093242322","https://openalex.org/W2094767250","https://openalex.org/W2096003243","https://openalex.org/W2097450119","https://openalex.org/W2101762862","https://openalex.org/W2103394361","https://openalex.org/W2104819369","https://openalex.org/W2105929907","https://openalex.org/W2107274852","https://openalex.org/W2107287502","https://openalex.org/W2108805155","https://openalex.org/W2111802820","https://openalex.org/W2112170705","https://openalex.org/W2112386737","https://openalex.org/W2114066392","https://openalex.org/W2115513398","https://openalex.org/W2117718508","https://openalex.org/W2120647667","https://openalex.org/W2121119246","https://openalex.org/W2121893520","https://openalex.org/W2124184213","https://openalex.org/W2128919163","https://openalex.org/W2128963487","https://openalex.org/W2131564374","https://openalex.org/W2134675761","https://openalex.org/W2134770687","https://openalex.org/W2136472480","https://openalex.org/W2138529478","https://openalex.org/W2139525458","https://openalex.org/W2139700465","https://openalex.org/W2142395584","https://openalex.org/W2143285031","https://openalex.org/W2149805979","https://openalex.org/W2150401511","https://openalex.org/W2151687739","https://openalex.org/W2152770536","https://openalex.org/W2152832979","https://openalex.org/W2153216347","https://openalex.org/W2153297237","https://openalex.org/W2157211509","https://openalex.org/W2157408003","https://openalex.org/W2159690123","https://openalex.org/W2162641287","https://openalex.org/W2165397843","https://openalex.org/W2166945572","https://openalex.org/W2171194355","https://openalex.org/W2171797989","https://openalex.org/W2290789437"],"related_works":["https://openalex.org/W2801036623","https://openalex.org/W2023506034","https://openalex.org/W2142312996","https://openalex.org/W2003282215","https://openalex.org/W2142768458","https://openalex.org/W2771702353","https://openalex.org/W1066809097","https://openalex.org/W2037842174","https://openalex.org/W4391855360","https://openalex.org/W2047221965"],"abstract_inverted_index":{"Psychosocial":[0],"therapies":[1,12,51],"play":[2],"an":[3],"important":[4],"role":[5],"in":[6,22,26,36,52,72,134,164],"the":[7,17,20,23,37,46,75,78,84,127,141,151,160,169],"treatment":[8,125],"of":[9,19,39,48,69,77,83,92,98,106,129,140,153,156],"schizophrenia.":[10],"These":[11],"are":[13,167],"aimed":[14],"at":[15],"improving":[16],"functioning":[18],"patient":[21],"community,":[24],"which":[25],"turn":[27],"can":[28],"lead":[29],"to":[30,100,120,123,181],"clinical":[31,96,165],"improvement,":[32],"such":[33],"as":[34],"reduction":[35],"number":[38],"relapses":[40],"or":[41],"hospitalizations.":[42],"Substantial":[43],"evidence":[44],"supports":[45],"use":[47],"many":[49],"psychosocial":[50],"schizophrenia,":[53,73],"including":[54,143],"cognitive":[55,61],"behavioral":[56],"therapy,":[57],"assertive":[58],"community":[59],"treatment,":[60],"remediation":[62],"and":[63,80,110,159],"functional":[64],"skills":[65],"training.":[66],"The":[67],"customization":[68],"pharmacological":[70],"therapy":[71],"besides":[74],"experience":[76],"clinician":[79],"individual":[81],"preferences":[82],"patient,":[85],"should":[86],"be":[87],"based":[88],"on":[89],"three":[90],"sets":[91],"objective":[93],"data:":[94],"1)":[95],"predictors":[97],"response":[99],"therapy;":[101,107],"2)":[102],"predictable":[103],"side":[104],"effects":[105],"3)":[108],"pharmacogenetic":[109],"pharmacogenomic":[111],"data.":[112],"It":[113],"has":[114],"been":[115],"made":[116],"a":[117],"considerable":[118],"effort":[119],"improve":[121],"adherence":[122],"antipsychotic":[124],"through":[126],"development":[128,152],"drugs":[130],"with":[131,178],"better":[132],"tolerability,":[133],"formulations":[135,155],"that":[136],"enable":[137],"long-term":[138],"administration":[139],"drug,":[142],"injectable":[144],"long-acting":[145],"(depot)":[146],"antipsychotics.":[147],"In":[148],"recent":[149],"years":[150],"these":[154,172],"atypical":[157],"antipsychotics":[158],"promising":[161],"results":[162],"obtained":[163],"trials":[166],"changing":[168],"attitude":[170],"toward":[171],"drugs,":[173],"traditionally":[174],"reserved":[175],"for":[176],"patients":[177],"repeated":[179],"non-adherence":[180],"treatment.":[182]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}