{"id":"https://openalex.org/W2376664579","doi":null,"title":"Antofloxacin for the treatment of spontaneous bacterial peritonitis","display_name":"Antofloxacin for the treatment of spontaneous bacterial peritonitis","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2376664579","mag":"2376664579"},"language":"en","primary_location":{"id":"mag:2376664579","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-BANG201405013.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2765077820","display_name":"Journal of Bengbu Medical College","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4361729672","host_organization_name":"Bengbu Medical College","host_organization_lineage":["https://openalex.org/P4361729672"],"host_organization_lineage_names":["Bengbu Medical College"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Bengbu Medical College","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027327711","display_name":"Xueqian Sun","orcid":"https://orcid.org/0000-0003-3258-9780","observed_orcids":["https://orcid.org/0000-0003-3258-9780"]},"institutions":[{"id":"https://openalex.org/I4210142329","display_name":"The Second Affiliated Hospital of Bengbu Medical College","ror":"https://ror.org/0441pfj90","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142329"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xueqian Sun","raw_affiliation_strings":["Department of Infectious Disease,The Second Affiliated Hospital of Bengbu Medical College"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Disease,The Second Affiliated Hospital of Bengbu Medical College","institution_ids":["https://openalex.org/I4210142329"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5027327711"],"corresponding_institution_ids":["https://openalex.org/I4210142329"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28530885,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spontaneous-bacterial-peritonitis","display_name":"spontaneous bacterial peritonitis","score":0.996999979019165},{"id":"https://openalex.org/keywords/community-acquired-infections","display_name":"community-acquired infections","score":0.9039999842643738},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.8489999771118164},{"id":"https://openalex.org/keywords/cefotaxime","display_name":"cefotaxime","score":0.8809999823570251},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.6460000276565552},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.9380000233650208},{"id":"https://openalex.org/keywords/alanine-aminotransferase","display_name":"alanine aminotransferase","score":0.8550000190734863},{"id":"https://openalex.org/keywords/bilirubin","display_name":"bilirubin","score":0.8080000281333923},{"id":"https://openalex.org/keywords/albumin","display_name":"albumin","score":0.6830000281333923},{"id":"https://openalex.org/keywords/qt-interval","display_name":"QT interval","score":0.9190000295639038}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9708956480026245},{"id":"https://openalex.org/C2777364826","wikidata":"https://www.wikidata.org/wiki/Q3128789","display_name":"Spontaneous bacterial peritonitis","level":3,"score":0.8996835947036743},{"id":"https://openalex.org/C2780199535","wikidata":"https://www.wikidata.org/wiki/Q223102","display_name":"Peritonitis","level":2,"score":0.6132605075836182},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6044164896011353},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5424289703369141},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.5300488471984863},{"id":"https://openalex.org/C65409693","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Statistical significance","level":2,"score":0.5278227925300598},{"id":"https://openalex.org/C2778719061","wikidata":"https://www.wikidata.org/wiki/Q417968","display_name":"Cefotaxime","level":3,"score":0.49419310688972473},{"id":"https://openalex.org/C2777513400","wikidata":"https://www.wikidata.org/wiki/Q104219","display_name":"Bilirubin","level":2,"score":0.48048678040504456},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.47936731576919556},{"id":"https://openalex.org/C2780434524","wikidata":"https://www.wikidata.org/wiki/Q1144385","display_name":"Prothrombin time","level":2,"score":0.45993757247924805},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.3815620243549347},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.35228991508483887},{"id":"https://openalex.org/C2780496750","wikidata":"https://www.wikidata.org/wiki/Q193889","display_name":"Ascites","level":2,"score":0.24151578545570374},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2376664579","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-BANG201405013.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2765077820","display_name":"Journal of Bengbu Medical College","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4361729672","host_organization_name":"Bengbu Medical College","host_organization_lineage":["https://openalex.org/P4361729672"],"host_organization_lineage_names":["Bengbu Medical College"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Bengbu Medical College","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2012654744","https://openalex.org/W147080890","https://openalex.org/W4213322181","https://openalex.org/W2040931893","https://openalex.org/W36414726","https://openalex.org/W2410075498","https://openalex.org/W2440609773","https://openalex.org/W4293353666","https://openalex.org/W7213247920","https://openalex.org/W4254510879"],"abstract_inverted_index":{"Objective:":[0],"To":[1],"evaluate":[2],"the":[3,10,57,68,74,128],"efficacy":[4],"and":[5,36,56,92,108,141],"safety":[6],"of":[7,12,137,145],"antofloxacin":[8,62,138],"in":[9,73,88,99,106,116],"treatment":[11,144],"community-acquired":[13,25,146],"uncomplicated":[14,26,147],"spontaneous":[15],"bacterial":[16],"peritonitis(":[17],"SBP)":[18],"infection.":[19],"Methods:":[20],"Fifty-one":[21],"cirrhotic":[22],"patients":[23],"with":[24],"SBP":[27],"were":[28,60],"divided":[29],"into":[30],"observation":[31,58,83],"group(":[32,38],"n":[33,39],"=":[34,40],"24)":[35],"control":[37,43],"27).":[41],"The":[42,119],"group":[44,59,84],"received":[45],"cefotaxime":[46],"2":[47],"g":[48],"intravenously2":[49],"times":[50],"a":[51,86],"day":[52],"for":[53,143],"10":[54,80],"days":[55,81],"given":[61],"400":[63],"mg":[64,72],"orally":[65],"once":[66],"on":[67],"first":[69],"day,then":[70],"200":[71],"following":[75],"9":[76],"days.":[77],"Results:":[78],"After":[79],"therapy,the":[82],"manifested":[85],"decrease":[87],"alanine":[89],"amino":[90],"transferase":[91],"total":[93,120],"bilirubin(":[94],"P":[95,101,111,131],"0.":[96,102,112,132],"05),an":[97],"increase":[98],"albumin(":[100],"01),no":[103],"significant":[104],"changes":[105],"creatinine":[107],"prothrombin":[109],"time(":[110],"05),and":[113],"no":[114,124],"extension":[115],"QT":[117],"intervals.":[118],"effective":[121,140],"rates":[122],"had":[123],"statistical":[125],"significance":[126],"between":[127],"two":[129],"groups(":[130],"05).":[133],"Conclusions:":[134],"Oral":[135],"administration":[136],"is":[139],"safe":[142],"SBP.":[148]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}