{"id":"https://openalex.org/W2375212801","doi":null,"title":"Effect of recombinant human growth hormone on prepuberty idiopathic short stature","display_name":"Effect of recombinant human growth hormone on prepuberty idiopathic short stature","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2375212801","mag":"2375212801"},"language":"en","primary_location":{"id":"mag:2375212801","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTotal-HNYY201008036.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2765017892","display_name":"Hainan Yixueyuan xuebao","issn_l":"1007-1237","issn":["1007-1237"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311890","host_organization_name":"Editorial Board of Journal of Hainan Medical University","host_organization_lineage":["https://openalex.org/P4310311890"],"host_organization_lineage_names":["Editorial Board of Journal of Hainan Medical University"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Hainan Yixueyuan xuebao","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108399817","display_name":"Su Li Cheng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Su Li Cheng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5108399817"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.34827697,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13091","display_name":"Human Health and Disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/recombinant-human-growth-hormone","display_name":"recombinant human growth hormone","score":0.9980000257492065},{"id":"https://openalex.org/keywords/idiopathic-short-stature","display_name":"idiopathic short stature","score":0.9729999899864197},{"id":"https://openalex.org/keywords/prepubertal-children","display_name":"prepubertal children","score":0.9900000095367432},{"id":"https://openalex.org/keywords/growth-rate","display_name":"growth rate","score":0.9419999718666077},{"id":"https://openalex.org/keywords/height-standard-deviation-score","display_name":"height standard deviation score","score":0.8790000081062317},{"id":"https://openalex.org/keywords/bone-age","display_name":"bone age","score":0.9789999723434448},{"id":"https://openalex.org/keywords/adult-height-prediction","display_name":"adult height prediction","score":0.8539999723434448},{"id":"https://openalex.org/keywords/subcutaneous-injection","display_name":"subcutaneous injection","score":0.7739999890327454},{"id":"https://openalex.org/keywords/treatment-side-effects","display_name":"treatment side effects","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C2910820727","wikidata":"https://www.wikidata.org/wiki/Q719723","display_name":"Prepuberty","level":3,"score":0.9648977518081665},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.935894250869751},{"id":"https://openalex.org/C89551170","wikidata":"https://www.wikidata.org/wiki/Q1777274","display_name":"Bone age","level":2,"score":0.8032063245773315},{"id":"https://openalex.org/C2778754045","wikidata":"https://www.wikidata.org/wiki/Q5988910","display_name":"Idiopathic short stature","level":4,"score":0.7489063143730164},{"id":"https://openalex.org/C2777871287","wikidata":"https://www.wikidata.org/wiki/Q7502090","display_name":"Short stature","level":2,"score":0.5886141061782837},{"id":"https://openalex.org/C2994100043","wikidata":"https://www.wikidata.org/wiki/Q29956617","display_name":"Human growth hormone","level":4,"score":0.583360493183136},{"id":"https://openalex.org/C2910124714","wikidata":"https://www.wikidata.org/wiki/Q1777274","display_name":"Bone maturation","level":3,"score":0.4972424805164337},{"id":"https://openalex.org/C2776390293","wikidata":"https://www.wikidata.org/wiki/Q2035485","display_name":"Subcutaneous injection","level":2,"score":0.49278929829597473},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4926775097846985},{"id":"https://openalex.org/C2984496839","wikidata":"https://www.wikidata.org/wiki/Q29956617","display_name":"Growth hormone","level":3,"score":0.4831390082836151},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4361902177333832},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.41711774468421936},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.37162870168685913}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2375212801","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTotal-HNYY201008036.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2765017892","display_name":"Hainan Yixueyuan xuebao","issn_l":"1007-1237","issn":["1007-1237"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311890","host_organization_name":"Editorial Board of Journal of Hainan Medical University","host_organization_lineage":["https://openalex.org/P4310311890"],"host_organization_lineage_names":["Editorial Board of Journal of Hainan Medical University"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Hainan Yixueyuan xuebao","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2351281197","https://openalex.org/W2063354700","https://openalex.org/W2362875021","https://openalex.org/W2895458988","https://openalex.org/W2391773425","https://openalex.org/W2391674411","https://openalex.org/W4293742241","https://openalex.org/W2389877594","https://openalex.org/W2393463841","https://openalex.org/W2379942568"],"abstract_inverted_index":{"Objective:To":[0],"discuss":[1],"the":[2,42,47,94],"effect":[3],"of":[4,14,36,59,97,131,139],"recombinant":[5],"human":[6],"growth":[7],"hormone(rhGH)on":[8],"prepuberty":[9],"idiopathic":[10],"short":[11],"stature(ISS).Methods:A":[12],"total":[13],"50":[15],"ISS":[16,132],"cases":[17,119],"were":[18,31,50,67,82],"randomly":[19],"divided":[20],"into":[21],"treatment":[22,29,78,80,98,122],"group":[23,26,30,49],"and":[24,72,87,105,129],"control":[25,48],"by":[27,33],"half.The":[28],"treated":[32,51],"subcutaneous":[34],"injection":[35,108],"rhGH":[37,53,121],"0.10-0.13":[38],"U/(kg\u00b7d)before":[39],"sleep":[40],"with":[41,99],"course":[43],"as":[44],"6-12":[45,55],"months,while":[46],"without":[52,117],"for":[54],"months.Bone":[56],"age,growth":[57],"velocity(GV),prediction":[58],"adult":[60],"height(PAH),height":[61],"standard":[62],"deviation":[63],"score(HtSDSBA),bone":[64],"age/actual":[65],"age":[66],"compared":[68],"between":[69,89],"two":[70,90],"groups.Results:GV":[71],"HtSDSBA":[73,88,130],"showed":[74],"significant":[75,83],"differences":[76,84],"after":[77,92],"in":[79,85,112],"group(P0.05).There":[81],"GV":[86,128],"groups":[91],"treatment(P0.05).At":[93],"early":[95],"stage":[96],"rhGH,one":[100],"case":[101],"had":[102],"transient":[103],"redness":[104],"swelling":[106],"at":[107],"site,and":[109],"slight":[110],"edema":[111],"both":[113],"lower":[114],"extremities,which":[115],"disappeared":[116],"treatment.Four":[118],"discontinue":[120],"due":[123],"to":[124],"puberty.Conclusions:GH":[125],"can":[126],"improve":[127],"children,with":[133],"inapparent":[134],"BA":[135],"increase.It":[136],"is":[137],"effective,and":[138],"no":[140],"serious":[141],"side":[142],"effect.":[143]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}