{"id":"https://openalex.org/W2374069442","doi":"https://doi.org/10.1016/j.nbd.2016.05.011","title":"Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC","display_name":"Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC","publication_year":2016,"publication_date":"2016-05-14","ids":{"openalex":"https://openalex.org/W2374069442","doi":"https://doi.org/10.1016/j.nbd.2016.05.011","mag":"2374069442","pmid":"https://pubmed.ncbi.nlm.nih.gov/27189756"},"language":"en","primary_location":{"id":"doi:10.1016/j.nbd.2016.05.011","doi":"https://doi.org/10.1016/j.nbd.2016.05.011","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.nbd.2016.05.011","pdf_url":null,"source":{"id":"https://openalex.org/S35878148","display_name":"Neurobiology of Disease","issn_l":"0969-9961","issn":["0969-9961","1095-953X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of Disease","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/a4e830d890a547978748184ac311bb5c","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004115570","display_name":"Bruce Do Van","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bruce Do Van","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045078189","display_name":"Flore Gouel","orcid":"https://orcid.org/0000-0002-1658-9986","observed_orcids":["https://orcid.org/0000-0002-1658-9986"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Flore Gouel","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022341854","display_name":"Aur\u00e9lie Jonneaux","orcid":"https://orcid.org/0000-0002-3568-2553","observed_orcids":["https://orcid.org/0000-0002-3568-2553"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aur\u00e9lie Jonneaux","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062935587","display_name":"Kelly Timmerman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Kelly Timmerman","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048586577","display_name":"Patrick Gel\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018718406","display_name":"Centre Hospitalier Universitaire de Lille","ror":"https://ror.org/02ppyfa04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3018718406"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Patrick Gel\u00e9","raw_affiliation_strings":["Biological Resources Centre, Lille University Hospital, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biological Resources Centre, Lille University Hospital, Lille, France","institution_ids":["https://openalex.org/I3018718406"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002651248","display_name":"Maud P\u00e9trault","orcid":"https://orcid.org/0009-0008-7337-0965","observed_orcids":["https://orcid.org/0009-0008-7337-0965","https://orcid.org/0000-0001-7024-8683"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Maud P\u00e9trault","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mich\u00e8le Bastide","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mich\u00e8le Bastide","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019004860","display_name":"Charlotte Laloux","orcid":"https://orcid.org/0000-0001-7039-9940","observed_orcids":["https://orcid.org/0000-0001-7039-9940"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Charlotte Laloux","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079362824","display_name":"Caroline Moreau","orcid":"https://orcid.org/0000-0002-5683-2709","observed_orcids":["https://orcid.org/0000-0002-5683-2709"]},"institutions":[{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Caroline Moreau","raw_affiliation_strings":["Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079246880","display_name":"R\u00e9gis Bordet","orcid":"https://orcid.org/0000-0003-3916-6422","observed_orcids":["https://orcid.org/0000-0003-3916-6422"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"R\u00e9gis Bordet","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056517132","display_name":"David Devos","orcid":"https://orcid.org/0000-0002-2417-799X","observed_orcids":["https://orcid.org/0000-0002-2417-799X"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I3018718406","display_name":"Centre Hospitalier Universitaire de Lille","ror":"https://ror.org/02ppyfa04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3018718406"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"David Devos","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France; Biological Resources Centre, Lille University Hospital, Lille, France; Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France","Biological Resources Centre, Lille University Hospital, Lille, France","Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France; Biological Resources Centre, Lille University Hospital, Lille, France; Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I3018718406","https://openalex.org/I59807433"]},{"raw_affiliation_string":"Biological Resources Centre, Lille University Hospital, Lille, France","institution_ids":["https://openalex.org/I3018718406"]},{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]},{"raw_affiliation_string":"Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I59807433"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110350949","display_name":"Jean-Christophe Devedjian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2802487185","display_name":"Universit\u00e9 du littoral c\u00f4te d'opale","ror":"https://ror.org/02gdcg342","country_code":"FR","type":"education","lineage":["https://openalex.org/I2802487185"]},{"id":"https://openalex.org/I3018718406","display_name":"Centre Hospitalier Universitaire de Lille","ror":"https://ror.org/02ppyfa04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3018718406"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Jean-Christophe Devedjian","raw_affiliation_strings":["Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France; Biological Resources Centre, Lille University Hospital, Lille, France; Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France; University of the Littoral Opal Coast, Calais, France. Electronic address: Jean-Christophe.Devedjian@univ-littoral.fr","Biological Resources Centre, Lille University Hospital, Lille, France","Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France","University of the Littoral Opal Coast, Calais, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France; Biological Resources Centre, Lille University Hospital, Lille, France; Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France; University of the Littoral Opal Coast, Calais, France. Electronic address: Jean-Christophe.Devedjian@univ-littoral.fr","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I2802487185","https://openalex.org/I3018718406","https://openalex.org/I59807433"]},{"raw_affiliation_string":"Biological Resources Centre, Lille University Hospital, Lille, France","institution_ids":["https://openalex.org/I3018718406"]},{"raw_affiliation_string":"Department of Medical Pharmacology/INSERM U1171, Lille Faculty of Medicine, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I59807433"]},{"raw_affiliation_string":"Department of Movement Disorders and Neurology, Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I59807433"]},{"raw_affiliation_string":"University of the Littoral Opal Coast, Calais, France","institution_ids":["https://openalex.org/I2802487185"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5110350949"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I2802487185","https://openalex.org/I3018718406","https://openalex.org/I59807433"],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":20.8084,"has_fulltext":false,"cited_by_count":710,"citation_normalized_percentile":{"value":0.99735199,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"94","issue":null,"first_page":"169","last_page":"178"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.70169997215271,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.70169997215271,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.24120000004768372,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13481","display_name":"Neurological diseases and metabolism","score":0.03440000116825104,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ferroptosis","display_name":"ferroptosis","score":1.0},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":1.0},{"id":"https://openalex.org/keywords/protein-kinase-c-alpha","display_name":"protein kinase C alpha","score":0.7839999794960022},{"id":"https://openalex.org/keywords/mek-activation","display_name":"MEK activation","score":0.7110000252723694},{"id":"https://openalex.org/keywords/ras-independent-signaling","display_name":"Ras-independent signaling","score":0.8669999837875366},{"id":"https://openalex.org/keywords/dopaminergic-neurons","display_name":"dopaminergic neurons","score":0.8429999947547913},{"id":"https://openalex.org/keywords/iron-dependent-cell-death","display_name":"iron-dependent cell death","score":0.8199999928474426},{"id":"https://openalex.org/keywords/organotypic-slice-cultures","display_name":"organotypic slice cultures","score":0.9300000071525574},{"id":"https://openalex.org/keywords/iron-chelators","display_name":"iron chelators","score":0.8970000147819519},{"id":"https://openalex.org/keywords/protein-kinase-c-inhibitors","display_name":"PKC inhibitors","score":0.8360000252723694},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.8610000014305115}],"concepts":[{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.8440380096435547},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.7739711999893188},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5819600820541382},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.548010528087616},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4704191982746124},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.4275974631309509},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4221007525920868},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4200972020626068},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.40176528692245483},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3864133954048157},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3638150990009308},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35879021883010864},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.29233700037002563},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.2845931053161621},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2136532962322235},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1258905529975891},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08357027173042297},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.06801897287368774}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008636","descriptor_name":"Mesencephalon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011493","descriptor_name":"Protein Kinase C","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013378","descriptor_name":"Substantia Nigra","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016923","descriptor_name":"Cell Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D059290","descriptor_name":"Dopaminergic Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.nbd.2016.05.011","doi":"https://doi.org/10.1016/j.nbd.2016.05.011","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.nbd.2016.05.011","pdf_url":null,"source":{"id":"https://openalex.org/S35878148","display_name":"Neurobiology of Disease","issn_l":"0969-9961","issn":["0969-9961","1095-953X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of Disease","raw_type":"journal-article"},{"id":"pmid:27189756","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27189756","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of disease","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a4e830d890a547978748184ac311bb5c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a4e830d890a547978748184ac311bb5c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Neurobiology of Disease, Vol 94, Iss , Pp 169-178 (2016)","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:a4e830d890a547978748184ac311bb5c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a4e830d890a547978748184ac311bb5c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Neurobiology of Disease, Vol 94, Iss , Pp 169-178 (2016)","raw_type":"article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1965147820","https://openalex.org/W1968918122","https://openalex.org/W1973041976","https://openalex.org/W1974069592","https://openalex.org/W1975617209","https://openalex.org/W1990711540","https://openalex.org/W1994231288","https://openalex.org/W1997183854","https://openalex.org/W1998404806","https://openalex.org/W2002490399","https://openalex.org/W2004283265","https://openalex.org/W2004628001","https://openalex.org/W2022516942","https://openalex.org/W2025494835","https://openalex.org/W2035898183","https://openalex.org/W2043390076","https://openalex.org/W2043781154","https://openalex.org/W2044176491","https://openalex.org/W2046441392","https://openalex.org/W2056333208","https://openalex.org/W2057632732","https://openalex.org/W2059373323","https://openalex.org/W2066276791","https://openalex.org/W2071839867","https://openalex.org/W2073455958","https://openalex.org/W2074191005","https://openalex.org/W2074892323","https://openalex.org/W2077044335","https://openalex.org/W2079705176","https://openalex.org/W2092195741","https://openalex.org/W2103369856","https://openalex.org/W2106296386","https://openalex.org/W2113017807","https://openalex.org/W2136271920","https://openalex.org/W2140273686","https://openalex.org/W2155863110"],"related_works":["https://openalex.org/W3013073107","https://openalex.org/W4311039745","https://openalex.org/W4406605346","https://openalex.org/W2568082326","https://openalex.org/W4407933429","https://openalex.org/W4327596361","https://openalex.org/W4399201174","https://openalex.org/W3133610583","https://openalex.org/W3114257724","https://openalex.org/W4416730620"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":56},{"year":2025,"cited_by_count":75},{"year":2024,"cited_by_count":91},{"year":2023,"cited_by_count":110},{"year":2022,"cited_by_count":118},{"year":2021,"cited_by_count":84},{"year":2020,"cited_by_count":81},{"year":2019,"cited_by_count":42},{"year":2018,"cited_by_count":31},{"year":2017,"cited_by_count":18},{"year":2016,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}