{"id":"https://openalex.org/W237367187","doi":"https://doi.org/10.1055/s-2007-1024313","title":"Orthotope Lebertransplantation bei einem 33-j\u00e4hrigen Patienten mit fulminanter Hepatitis-B- und HIV-Infektion","display_name":"Orthotope Lebertransplantation bei einem 33-j\u00e4hrigen Patienten mit fulminanter Hepatitis-B- und HIV-Infektion","publication_year":2008,"publication_date":"2008-03-25","ids":{"openalex":"https://openalex.org/W237367187","doi":"https://doi.org/10.1055/s-2007-1024313","mag":"237367187","pmid":"https://pubmed.ncbi.nlm.nih.gov/10829796"},"language":"de","primary_location":{"id":"doi:10.1055/s-2007-1024313","doi":"https://doi.org/10.1055/s-2007-1024313","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2007-1024313","pdf_url":null,"source":{"id":"https://openalex.org/S38943393","display_name":"DMW - Deutsche Medizinische Wochenschrift","issn_l":"0012-0472","issn":["0012-0472","1439-4413"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"DMW - Deutsche Medizinische Wochenschrift","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111690989","display_name":"Kirsten Schliefer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]},{"id":"https://openalex.org/I2799391451","display_name":"University Hospital Bonn","ror":"https://ror.org/01xnwqx93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799391451"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"K. Schliefer","raw_affiliation_strings":["Medizinische Klinik und Poliklinik I, Universit\u00e4t Bonn. k.schliefer@uni-bonn.de","Medizinische Klinik und Poliklinik I, Universit\u00e4t Bonn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medizinische Klinik und Poliklinik I, Universit\u00e4t Bonn. k.schliefer@uni-bonn.de","institution_ids":["https://openalex.org/I135140700"]},{"raw_affiliation_string":"Medizinische Klinik und Poliklinik I, Universit\u00e4t Bonn","institution_ids":["https://openalex.org/I135140700","https://openalex.org/I2799391451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002019738","display_name":"W. Dieter Paar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W.D. Paar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"G. Aydemir","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. Aydemir","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024478900","display_name":"Martin J. Wolff","orcid":"https://orcid.org/0000-0003-4391-2395","observed_orcids":["https://orcid.org/0000-0003-4391-2395"]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Wolff","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Allgemein-, Viszeral, Thorax- und Gef\u00e4\u00dfchirurgie (Direktor: Prof. Dr. A. Hirner), Universit\u00e4t Bonn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Allgemein-, Viszeral, Thorax- und Gef\u00e4\u00dfchirurgie (Direktor: Prof. Dr. A. Hirner), Universit\u00e4t Bonn","institution_ids":["https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111740201","display_name":"J. K. Rockstroh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J.K. Rockstroh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058633927","display_name":"Ulrich Spengler","orcid":"https://orcid.org/0000-0002-8746-2413","observed_orcids":["https://orcid.org/0000-0002-8746-2413"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"U. Spengler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111631218","display_name":"Tilman Sauerbruch","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. Sauerbruch","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7027,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.73861134,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"125","issue":"17","first_page":"523","last_page":"526"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.9355000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.9355000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.02250000089406967,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/orthotopic-liver-transplantation","display_name":"orthotopic liver transplantation","score":0.949999988079071},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.8370000123977661},{"id":"https://openalex.org/keywords/hepatitis-b","display_name":"hepatitis B","score":0.8040000200271606},{"id":"https://openalex.org/keywords/fulminant-hepatitis","display_name":"fulminant hepatitis","score":0.8539999723434448},{"id":"https://openalex.org/keywords/hiv-hbv-coinfection","display_name":"HIV/HBV coinfection","score":0.6909999847412109},{"id":"https://openalex.org/keywords/cd4-count","display_name":"CD4 count","score":0.6359999775886536},{"id":"https://openalex.org/keywords/hiv-viral-load","display_name":"HIV viral load","score":0.578000009059906},{"id":"https://openalex.org/keywords/post-transplant-complications","display_name":"post-transplant complications","score":0.6710000038146973},{"id":"https://openalex.org/keywords/kidney-failure","display_name":"renal failure","score":0.7229999899864197},{"id":"https://openalex.org/keywords/cytomegalovirus-infection","display_name":"cytomegalovirus infection","score":0.878000020980835},{"id":"https://openalex.org/keywords/cyclosporine-induced-hypertension","display_name":"cyclosporine-induced hypertension","score":0.9129999876022339},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.8930000066757202},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.7889999747276306}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9233604669570923},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.654266357421875},{"id":"https://openalex.org/C2779634585","wikidata":"https://www.wikidata.org/wiki/Q1334541","display_name":"Pleural effusion","level":2,"score":0.5469706654548645},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.49287939071655273},{"id":"https://openalex.org/C2781107259","wikidata":"https://www.wikidata.org/wiki/Q5508364","display_name":"Fulminant","level":2,"score":0.47195711731910706},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46869730949401855},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4648854434490204},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.414816677570343},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.36757972836494446},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3383689522743225},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3236679434776306}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006501","descriptor_name":"Hepatic Encephalopathy","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006501","descriptor_name":"Hepatic Encephalopathy","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D012086","descriptor_name":"Reoperation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016031","descriptor_name":"Liver Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017093","descriptor_name":"Liver Failure","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D017093","descriptor_name":"Liver Failure","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D019694","descriptor_name":"Hepatitis B, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019694","descriptor_name":"Hepatitis B, Chronic","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1055/s-2007-1024313","doi":"https://doi.org/10.1055/s-2007-1024313","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2007-1024313","pdf_url":null,"source":{"id":"https://openalex.org/S38943393","display_name":"DMW - Deutsche Medizinische Wochenschrift","issn_l":"0012-0472","issn":["0012-0472","1439-4413"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"DMW - Deutsche Medizinische Wochenschrift","raw_type":"journal-article"},{"id":"pmid:10829796","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10829796","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Deutsche medizinische Wochenschrift (1946)","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.7900000214576721,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2617203504","https://openalex.org/W1994625936","https://openalex.org/W2018437533","https://openalex.org/W2322816321","https://openalex.org/W2150136730","https://openalex.org/W2064680752","https://openalex.org/W2318384249","https://openalex.org/W2052103535","https://openalex.org/W2067989334","https://openalex.org/W2127239856"],"abstract_inverted_index":{"HISTORY":[0],"AND":[1,78],"CLINICAL":[2],"FINDINGS:":[3],"A":[4],"33-year-old":[5],"man":[6],"with":[7,63,170,238],"fulminant":[8],"hepatitis":[9],"B":[10],"infection":[11,124],"was":[12,31,43,55,68,95,151],"to":[13,34,118,189,205],"have":[14,35,184],"an":[15,36],"orthotopic":[16],"liver":[17,116,172],"transplantation":[18,83],"(OLTX)":[19],"because":[20],"of":[21,110,114,137],"the":[22,40,81,111,115,135,143,203],"otherwise":[23],"poor":[24],"prognosis.":[25],"During":[26,153],"preparations":[27],"for":[28,179],"it":[29],"he":[30,46,157],"found":[32],"also":[33],"HIV-infection.":[37],"INVESTIGATIONS:":[38],"Preoperatively":[39],"Quick":[41],"value":[42],"9%,":[44],"and":[45,125,147,164,182],"had":[47,84,158],"a":[48,64,89,159],"grade":[49],"2":[50,155],"encephalopathy.":[51],"His":[52],"immune":[53,149],"status":[54],"impaired:":[56],"477":[57],"CD4-T-helper":[58],"cells/microliter.":[59],"Virus":[60],"load,":[61],"measured":[62,166],"quantitative":[65],"HIV-RNA":[66,165],"test,":[67],"<":[69],"80":[70,168],"copies/ml":[71,169],"(i.e.":[72],"below":[73,167],"demonstrable":[74],"level).":[75],"DIAGNOSIS,":[76],"TREATMENT":[77],"COURSE:":[79],"After":[80],"first":[82],"ended":[85],"in":[86,208,214,235],"organ":[87],"failure,":[88],"second":[90],"one":[91],"two":[92],"days":[93],"later":[94],"successful.":[96],"But":[97,128],"there":[98,183],"were":[99,131],"several":[100],"complications":[101,187],"postoperatively:":[102],"ischaemic-toxic":[103],"tubular":[104],"renal":[105],"failure":[106],"requiring":[107],"haemodialysis,":[108],"underperfusion":[109],"right":[112],"lobe":[113],"due":[117],"arterial":[119],"stenosis,":[120],"pleural":[121],"effusion,":[122],"cytomegalovirus":[123],"cyclosporin-induced":[126],"hypertension.":[127],"all":[129],"these":[130,154],"successfully":[132],"managed.":[133],"At":[134],"time":[136],"this":[138,215],"report,":[139],"27":[140],"months":[141],"later,":[142],"patient":[144],"felt":[145],"well":[146],"his":[148],"state":[150],"stable.":[152],"years":[156],"practically":[160],"normal":[161],"T-helper":[162],"count":[163],"good":[171],"function.":[173],"There":[174],"has":[175],"been":[176,185],"no":[177,186],"indication":[178],"antiviral":[180,198],"treatment":[181,222],"relating":[188],"immunosuppression.":[190],"CONCLUSION:":[191],"The":[192,211],"low":[193],"life":[194],"expectancy":[195],"before":[196],"effective":[197],"drugs":[199],"are":[200],"available":[201],"explains":[202],"reluctance":[204],"perform":[206],"OLTX":[207,231],"HIV-infected":[209],"patients.":[210],"favourable":[212],"course":[213],"case,":[216],"using":[217],"highly":[218],"efficacious":[219],"combined":[220],"antiretroviral":[221],"now":[223],"being":[224],"available,":[225],"indicates":[226],"that":[227],"after":[228],"careful":[229],"consideration,":[230],"can":[232],"be":[233],"performed":[234],"selected":[236],"patients":[237],"HIV.":[239]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}