{"id":"https://openalex.org/W2372844409","doi":null,"title":"Observation of the clinical efficacy of subclinical hypothyroidism, clinical hypothyroidism treated with levothyroxine","display_name":"Observation of the clinical efficacy of subclinical hypothyroidism, clinical hypothyroidism treated with levothyroxine","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2372844409","mag":"2372844409"},"language":"en","primary_location":{"id":"mag:2372844409","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTotal-GYKX201502018.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764707663","display_name":"China Medicine and Pharmacy","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"China Medicine and Pharmacy","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039106931","display_name":"Zhang Sil","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107961","display_name":"Zhengzhou Children's Hospital","ror":"https://ror.org/01jfd9z49","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210107961"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhang Sil","raw_affiliation_strings":["Department of Quality Control,Children's Hospital of Zhengzhou City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Quality Control,Children's Hospital of Zhengzhou City","institution_ids":["https://openalex.org/I4210107961"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5039106931"],"corresponding_institution_ids":["https://openalex.org/I4210107961"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.24089463,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subclinical-hypothyroidism","display_name":"subclinical hypothyroidism","score":0.9819999933242798},{"id":"https://openalex.org/keywords/overt-hypothyroidism","display_name":"overt hypothyroidism","score":0.9919999837875366},{"id":"https://openalex.org/keywords/levothyroxine","display_name":"levothyroxine","score":0.9890000224113464},{"id":"https://openalex.org/keywords/thyroid-function","display_name":"thyroid function","score":0.699999988079071},{"id":"https://openalex.org/keywords/serum-lipids","display_name":"serum lipids","score":0.7059999704360962},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.9049999713897705},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9819999933242798},{"id":"https://openalex.org/keywords/free-thyroxine","display_name":"free thyroxine","score":0.7870000004768372},{"id":"https://openalex.org/keywords/free-triiodothyronine","display_name":"free triiodothyronine","score":0.9120000004768372},{"id":"https://openalex.org/keywords/thyroid-stimulating-hormone","display_name":"thyroid-stimulating hormone","score":0.9589999914169312}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9720757007598877},{"id":"https://openalex.org/C2775883008","wikidata":"https://www.wikidata.org/wiki/Q773449","display_name":"Levothyroxine","level":3,"score":0.8993611931800842},{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.8798023462295532},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6598973870277405},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5568806529045105},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5489171743392944},{"id":"https://openalex.org/C2992053201","wikidata":"https://www.wikidata.org/wiki/Q2585693","display_name":"Clinical efficacy","level":2,"score":0.5333960056304932},{"id":"https://openalex.org/C2993291352","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid function","level":3,"score":0.4826541543006897},{"id":"https://openalex.org/C139572402","wikidata":"https://www.wikidata.org/wiki/Q4927820","display_name":"Blood lipids","level":3,"score":0.47470277547836304},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.474578857421875},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.4636842608451843},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4375951290130615},{"id":"https://openalex.org/C2777886399","wikidata":"https://www.wikidata.org/wiki/Q211544","display_name":"Thyroid-stimulating hormone","level":3,"score":0.41488009691238403},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.1956160068511963}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2372844409","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTotal-GYKX201502018.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764707663","display_name":"China Medicine and Pharmacy","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"China Medicine and Pharmacy","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2362827212","https://openalex.org/W2369657890","https://openalex.org/W2378522173","https://openalex.org/W2381978289","https://openalex.org/W2379901280","https://openalex.org/W2359601037","https://openalex.org/W2998784866","https://openalex.org/W3127903989","https://openalex.org/W2077977355","https://openalex.org/W3032343839"],"abstract_inverted_index":{"Objective":[0],"To":[1],"observe":[2],"the":[3,7,34,62,81,95,124,127,143],"clinical":[4,146,158],"efficacy":[5,144],"and":[6,55,72,77,91,107,111,121,152],"effection":[8],"on":[9],"blood":[10,73,154],"lipid":[11,74,155],"level":[12],"of":[13,36,52,94,137,145],"subclinical":[14,138],"hypothyroidism,clinical":[15],"hypothyroidism":[16,24,139],"treated":[17],"with":[18,80],"levothyroxin.":[19],"Methods":[20],"Collected":[21],"144":[22],"cases":[23,39],"patients,they":[25],"were":[26,46,65,84,130],"randomly":[27],"divided":[28],"into":[29],"two":[30,44,82,128],"groups":[31,45,83,129],"according":[32],"to":[33],"order":[35],"treatment,":[37,59,88],"72":[38],"in":[40,43,61,150],"each":[41],"group.Patients":[42],"both":[47],"given":[48,66],"hypoglycemic,pressure":[49],"control,":[50],"expansion":[51],"coronary":[53],"artery":[54],"other":[56],"conventional":[57],"symptomatic":[58],"patients":[60],"observation":[63,96],"group":[64,97],"levothyroxine":[67],"sodium.":[68],"The":[69],"hormone":[70],"levels":[71,75,93,113],"before":[76,105,119],"after":[78],"treatment":[79,106,120,136],"compared.":[85],"Results":[86],"After":[87],"FT3,":[89],"FT4":[90],"TSH":[92],"were(6.77\u00b10.72)pmol/L,(13.56\u00b11.52)pmol/L":[98],"and(3.25\u00b11.20)":[99],"m":[100],"IU/L,":[101],"significantly":[102,116,141],"improved":[103],"than":[104,118],"control":[108,122],"group;while":[109],"TC":[110],"TG":[112],"were(4.15\u00b10.88)mmol/L":[114],"and(1.65\u00b10.32)mmol/L,":[115],"reduced":[117],"group,and":[123],"difference":[125],"between":[126],"statistically":[131],"significant(P":[132],"0.05).":[133],"Conclusion":[134],"Levothyroxine":[135],"can":[140],"improve":[142],"hypothyroidism,":[147],"thyroid":[148],"function":[149],"patients,":[151],"reduce":[153],"levels,":[156],"worthy":[157],"widely.":[159]},"counts_by_year":[],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}