{"id":"https://openalex.org/W2371868898","doi":null,"title":"[Erythrocyte native immune adhering function (ENIAF) in patients with hematopoietic and lymphoid neoplasms and its effect on NK Cell killing activity].","display_name":"[Erythrocyte native immune adhering function (ENIAF) in patients with hematopoietic and lymphoid neoplasms and its effect on NK Cell killing activity].","publication_year":2007,"publication_date":"2007-10-01","ids":{"openalex":"https://openalex.org/W2371868898","mag":"2371868898","pmid":"https://pubmed.ncbi.nlm.nih.gov/17956686"},"language":"en","primary_location":{"id":"pmid:17956686","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17956686","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhongguo shi yan xue ye xue za zhi","raw_type":"English Abstract"},"volume":null,"type":"other","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019680315","display_name":"Nai-Hong Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160763","display_name":"Shanxi Provincial People\u2019s Hospital","ror":"https://ror.org/057ckzt47","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I17721919","https://openalex.org/I4210160763"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Nai-Hong Zhang","raw_affiliation_strings":["Department of Hematology, Shanxi People Hospital, Taiyuan 030012, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Shanxi People Hospital, Taiyuan 030012, China","institution_ids":["https://openalex.org/I4210160763"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mei Feng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mei Feng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101079766","display_name":"Yujin Lu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yu-Jin Lu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100685878","display_name":"Lei Zhu","orcid":"https://orcid.org/0000-0002-5933-7762","observed_orcids":["https://orcid.org/0000-0002-5933-7762"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lei Zhu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019619645","display_name":"Jie Liu","orcid":"https://orcid.org/0000-0001-6768-3115","observed_orcids":["https://orcid.org/0000-0001-6768-3115"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jie Liu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030356836","display_name":"Hong-Peng Gao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hong-Peng Gao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100367626","display_name":"Weimin Li","orcid":"https://orcid.org/0000-0003-0985-0311","observed_orcids":["https://orcid.org/0000-0003-0985-0311"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wei-Min Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5105454746","display_name":"Zhenhua Qiao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhen-Hua Qiao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"5","first_page":"1037","last_page":"41"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nk-cell-cytotoxicity","display_name":"NK cell cytotoxicity","score":0.8830000162124634},{"id":"https://openalex.org/keywords/hematologic-malignancies","display_name":"hematologic malignancies","score":0.9610000252723694},{"id":"https://openalex.org/keywords/lymphoid-malignancies","display_name":"lymphoid malignancies","score":0.9959999918937683},{"id":"https://openalex.org/keywords/erythrocyte-rosettes","display_name":"erythrocyte rosettes","score":0.722000002861023},{"id":"https://openalex.org/keywords/k562-cells","display_name":"K562 cells","score":0.8889999985694885}],"concepts":[{"id":"https://openalex.org/C171122931","wikidata":"https://www.wikidata.org/wiki/Q6324626","display_name":"K562 cells","level":3,"score":0.8068283796310425},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.6621631383895874},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6469323635101318},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.524770200252533},{"id":"https://openalex.org/C2781414804","wikidata":"https://www.wikidata.org/wiki/Q7368701","display_name":"Rosette (schizont appearance)","level":2,"score":0.4816409647464752},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4371023178100586},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.39479392766952515},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.357307106256485},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.3092452883720398},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.13743948936462402},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.11803975701332092}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007104","descriptor_name":"Immune Adherence Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007104","descriptor_name":"Immune Adherence Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007104","descriptor_name":"Immune Adherence Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012397","descriptor_name":"Rosette Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012397","descriptor_name":"Rosette Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012397","descriptor_name":"Rosette Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D020014","descriptor_name":"K562 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020014","descriptor_name":"K562 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020014","descriptor_name":"K562 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":1,"locations":[{"id":"pmid:17956686","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17956686","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhongguo shi yan xue ye xue za zhi","raw_type":"English Abstract"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4300000071525574}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2408314916","https://openalex.org/W2254359459","https://openalex.org/W2041608343","https://openalex.org/W2122641753","https://openalex.org/W2350489353","https://openalex.org/W2407260213","https://openalex.org/W2058956107","https://openalex.org/W2436708276","https://openalex.org/W2421138571","https://openalex.org/W44017933","https://openalex.org/W2962751759","https://openalex.org/W2313913691","https://openalex.org/W2316545770","https://openalex.org/W2615861705","https://openalex.org/W2416127356","https://openalex.org/W2369691912","https://openalex.org/W2399255442","https://openalex.org/W1974580479","https://openalex.org/W2410017173","https://openalex.org/W1976922850"],"abstract_inverted_index":{"The":[0,35,125,165,190],"objective":[1],"of":[2,10,18,32,53,89,102,116,131,136,150,155,167,193,199,219,230,238,251,255,265,273,277],"this":[3],"study":[4],"was":[5,38,82,91,109,120,143,161,176,202],"to":[6,258,262],"investigate":[7],"the":[8,29,87,99,114,117,129,148,236,249,252,271,274],"change":[9,115,264],"native":[11],"immune":[12],"adhering":[13],"function":[14,276],"(ENIAF)":[15],"in":[16,169,181,196,240],"self-plasma":[17],"patients":[19,54,157,170,241,278],"with":[20,40,60,171,228,242,279],"hematologic":[21,172],"and":[22,25,49,140,147,158,173,209,244,281],"lymphoid":[23,174,245,282],"neoplasms":[24,175,246],"its":[26],"effect":[27],"on":[28],"killing":[30,100,118,191,253],"activity":[31,101,119,254],"NK":[33,103,194,256],"cells.":[34],"whole":[36],"blood":[37,47,198],"anticoagulated":[39],"citric":[41],"acid.":[42],"5":[43],"microl":[44,51,62],"precipitated":[45],"red":[46],"cells":[48,65,95,104,142,160,195,257],"500":[50],"plasma":[52],"or":[55,79],"controls":[56,139,221],"were":[57],"directly":[58],"mixed":[59],"750":[61],"quantitative":[63],"K562":[64,74,94,141,159,259],"at":[66],"37":[67],"degrees":[68],"C":[69],"for":[70,270],"30":[71],"minutes.":[72],"One":[73],"cell":[75],"attached":[76],"by":[77,111,134,153,212,224],"one":[78,85],"more":[80],"erythrocytes":[81],"counted":[83],"as":[84,96],"rosette,":[86],"ratio":[88,130,149],"rosettes":[90,132,151],"calculated.":[92],"Using":[93],"target":[97],"cells,":[98,260],"isolated":[105],"from":[106],"normal":[107,138,200,220],"persons":[108],"detected":[110],"MTT":[112],"assay,":[113],"observed":[121],"after":[122,216],"adding":[123,207,217],"RBCs.":[124],"results":[126],"indicated":[127],"that":[128,180,235],"formed":[133,152],"RBCs":[135,154,218,229,239],"21":[137],"15.3%":[144],"+/-":[145,163,214,226],"6.4%,":[146],"24":[156],"7.6%":[162,227],"7.0%.":[164],"ability":[166],"ENIAF":[168,237,266],"significantly":[177],"lower":[178],"than":[179],"healthy":[182],"individuals":[183,201],"(t":[184],"=":[185],"3.61,":[186],"p":[187],"<":[188],"0.001).":[189],"rate":[192],"peripheral":[197],"67%":[203],"-":[204],"71%":[205],"without":[206],"RBCs,":[208],"it":[210],"increased":[211],"14.7%":[213],"5.2%":[215],"but":[222],"decreased":[223],"4.3%":[225],"patients.":[231],"It":[232],"is":[233],"concluded":[234],"hematopoietic":[243,280],"decreases,":[247],"accompanying":[248],"reduction":[250],"so":[261],"detect":[263],"may":[267],"be":[268],"helpful":[269],"assessment":[272],"immunological":[275],"neoplasms.":[283]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2025-10-10T00:00:00"}