{"id":"https://openalex.org/W2371628387","doi":null,"title":"[Immunosuppressive effect of Tibetan medicine, Artemisia vestita Wall Extract].","display_name":"[Immunosuppressive effect of Tibetan medicine, Artemisia vestita Wall Extract].","publication_year":2006,"publication_date":"2006-11-01","ids":{"openalex":"https://openalex.org/W2371628387","mag":"2371628387","pmid":"https://pubmed.ncbi.nlm.nih.gov/17236592"},"language":"zh","primary_location":{"id":"pmid:17236592","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17236592","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075536210","display_name":"Jule Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I140786321","display_name":"Tibet University","ror":"https://ror.org/05petvd47","country_code":"CN","type":"education","lineage":["https://openalex.org/I140786321"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ju-Le Wang","raw_affiliation_strings":["Medical College of Tibet University, Lasa 850002, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Tibet University, Lasa 850002, China","institution_ids":["https://openalex.org/I140786321"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007249050","display_name":"Chang-Shan Li","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chang-Shan Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110372557","display_name":"Zhu Dun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhu Dun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5101082316","display_name":"Huiying Zhou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hui-Ying Zhou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.51490847,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"37","issue":"6","first_page":"908","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13026","display_name":"Natural Compounds in Disease Treatment","score":0.38920000195503235,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13026","display_name":"Natural Compounds in Disease Treatment","score":0.38920000195503235,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.29490000009536743,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.10909999907016754,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artemisia-vestita","display_name":"Artemisia vestita","score":0.9769999980926514},{"id":"https://openalex.org/keywords/tibetan-medicine","display_name":"Tibetan medicine","score":0.9020000100135803},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.8560000061988831},{"id":"https://openalex.org/keywords/splenocyte-proliferation","display_name":"splenocyte proliferation","score":0.8379999995231628},{"id":"https://openalex.org/keywords/mixed-lymphocyte-reaction","display_name":"mixed lymphocyte reaction","score":0.9919999837875366},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.9539999961853027},{"id":"https://openalex.org/keywords/mmp-9","display_name":"MMP-9","score":0.9129999876022339},{"id":"https://openalex.org/keywords/t-cell-adhesion","display_name":"T cell adhesion","score":0.8859999775886536},{"id":"https://openalex.org/keywords/cell-mediated-immunity","display_name":"cell-mediated immunity","score":0.5590000152587891},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.453000009059906}],"concepts":[{"id":"https://openalex.org/C189976730","wikidata":"https://www.wikidata.org/wiki/Q3493700","display_name":"Splenocyte","level":3,"score":0.9832444190979004},{"id":"https://openalex.org/C2778740727","wikidata":"https://www.wikidata.org/wiki/Q12055129","display_name":"Mixed lymphocyte reaction","level":4,"score":0.6556271314620972},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5279202461242676},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.495660662651062},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.46895474195480347},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.46881651878356934},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44574958086013794},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.420170396566391},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4114212095737457},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32077956199645996},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3074268698692322},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.20081818103790283},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1777271032333374},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.07495260238647461}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003208","descriptor_name":"Concanavalin A","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007376","descriptor_name":"Interleukin-2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008813","descriptor_name":"Mice, Inbred ICR","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010853","descriptor_name":"Picryl Chloride","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018609","descriptor_name":"Tibet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019169","descriptor_name":"Jurkat Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019306","descriptor_name":"Artemisia","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D020780","descriptor_name":"Matrix Metalloproteinase 9","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":1,"locations":[{"id":"pmid:17236592","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17236592","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2077495528","https://openalex.org/W2999691206","https://openalex.org/W2101216729","https://openalex.org/W2026496537","https://openalex.org/W2765885997","https://openalex.org/W3015414144","https://openalex.org/W4252387797","https://openalex.org/W4408982972","https://openalex.org/W2024369550","https://openalex.org/W2044048255"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"assess":[2],"the":[3,21,29,34,53,58,80,128,138,166,171,184],"immunosuppressive":[4],"effect":[5,107,126],"of":[6,18,31,36,46,55,60,82,111,130,140,154,168,173,178,188],"Artemisia":[7],"vestita":[8],"Wall":[9],"Extract":[10],"(AV-ext)":[11],"on":[12,33,57,84,108,127,137,147],"mice.":[13],"METHODS:":[14],"The":[15],"proliferative":[16,109],"reaction":[17,24,45,110,117,187],"lymphocyte":[19],"and":[20,41,72,89,114,146,151,170],"mixed":[22,115],"lymphocytes":[23,116],"were":[25,76],"used":[26,50],"to":[27,78,99,157],"determine":[28],"effects":[30,54,81],"AV-ext":[32,56,83,94,181],"proliferation":[35,167],"mouse":[37,47,64,85,100,112,134,143,158,189],"splenocyte":[38,48,66,113,169,177],"in":[39,42,67],"vitro":[40],"vivo;":[43],"Proliferative":[44],"was":[49],"for":[51,161],"detecting":[52],"level":[59,129],"IL-2":[61,131],"secreted":[62,132],"by":[63,119,133,142,175],"activated":[65,86,135,144,176],"vitro.":[68],"Gelatin":[69],"enzymogram":[70],"method":[71,75],"adherence":[73],"analytical":[74],"employed":[77],"disclose":[79],"T-lymphocytes":[87],"mobility":[88],"adherence.":[90,148],"RESULTS:":[91],"1-100":[92],"microg/mL":[93],"exerted":[95],"no":[96],"obvious":[97,105,124],"toxicity":[98],"splenocyte,":[101,136],"but":[102],"it":[103],"had":[104,123],"inhibitory":[106,125],"induced":[118],"ConA.":[120],"It":[121],"also":[122],"production":[139],"MMP-9":[141,174],"T-lymphocytes,":[145],"150":[149],"mg/kg":[150,153],"300":[152],"AV-ext,":[155],"given":[156],"per":[159],"os":[160],"7":[162],"days,":[163],"could":[164],"inhibit":[165,183],"secretion":[172],"mouse.":[179],"CONCLUSION:":[180],"can":[182],"cellular":[185],"immune":[186],"obviously.":[190]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}