{"id":"https://openalex.org/W2370537410","doi":null,"title":"Probucol Improve Prognosis and Inflammation after Percutaneous Coronary Intervention in the Patients with Acute Myocardial Infarction","display_name":"Probucol Improve Prognosis and Inflammation after Percutaneous Coronary Intervention in the Patients with Acute Myocardial Infarction","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2370537410","mag":"2370537410"},"language":"en","primary_location":{"id":"mag:2370537410","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-SYYX200801006.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2765046006","display_name":"Journal of Shenyang Medical College","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Shenyang Medical College","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103610427","display_name":"Li Chun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1099802","display_name":"Shenyang Medical College","ror":"https://ror.org/02y9xvd02","country_code":"CN","type":"education","lineage":["https://openalex.org/I1099802"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Li Chun","raw_affiliation_strings":["Department of Cardiology, Shenzhou Hospital Affiliated to Shenyang Medical College, Shenyang 110002, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Shenzhou Hospital Affiliated to Shenyang Medical College, Shenyang 110002, China","institution_ids":["https://openalex.org/I1099802"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5103610427"],"corresponding_institution_ids":["https://openalex.org/I1099802"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.37110922,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.5508000254631042,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.5508000254631042,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.17829999327659607,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.08190000057220459,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/probucol","display_name":"probucol","score":0.9990000128746033},{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.9909999966621399},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"percutaneous coronary intervention","score":1.0},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7419999837875366},{"id":"https://openalex.org/keywords/simvastatin","display_name":"simvastatin","score":0.8399999737739563},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9290000200271606},{"id":"https://openalex.org/keywords/cd40-ligand","display_name":"CD40 ligand","score":0.9300000071525574},{"id":"https://openalex.org/keywords/p-selectin","display_name":"P-selectin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.5080000162124634},{"id":"https://openalex.org/keywords/cardiac-events","display_name":"cardiac events","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C2776167589","wikidata":"https://www.wikidata.org/wiki/Q10354103","display_name":"Probucol","level":3,"score":0.977580189704895},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8863779306411743},{"id":"https://openalex.org/C45393284","wikidata":"https://www.wikidata.org/wiki/Q191012","display_name":"Conventional PCI","level":3,"score":0.822812020778656},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.7183864116668701},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.7115015983581543},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6991713643074036},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6841265559196472},{"id":"https://openalex.org/C2776329913","wikidata":"https://www.wikidata.org/wiki/Q670131","display_name":"Simvastatin","level":2,"score":0.6182873845100403},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5072545409202576},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.08894497156143188}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2370537410","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-SYYX200801006.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2765046006","display_name":"Journal of Shenyang Medical College","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Shenyang Medical College","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3029412240","https://openalex.org/W2069561072","https://openalex.org/W2367667402","https://openalex.org/W7165766334","https://openalex.org/W7128047032","https://openalex.org/W2392509309","https://openalex.org/W3171630602","https://openalex.org/W2387553477","https://openalex.org/W2348979225","https://openalex.org/W2394332684"],"abstract_inverted_index":{"Objective:To":[0],"investigate":[1],"the":[2,15,50,116],"value":[3],"of":[4,52,67,71,92],"probucol":[5,27,97],"at":[6,60,76,99],"prognosis":[7,110],"and":[8,29,49,69,94,111],"inflammation":[9,112],"after":[10,80,101,113],"percutaneous":[11],"coronary":[12],"intervention(PCI)":[13],"in":[14,63,82,96,115],"patients":[16,21,117],"with":[17,22,105,118],"acute":[18],"myocardial":[19],"infarction(AMI).Methods:Eight-two":[20],"AMI":[23],"were":[24,47,57,74,85,103],"divided":[25],"into":[26],"group(41patients)":[28,31],"control":[30],"randomly.Probucol":[32],"group":[33,40,98],"was":[34],"given":[35,41],"Probucol":[36,108],"500mg":[37],"Bid":[38],"po;control":[39],"Simvastatin":[42],"10mg":[43],"Qd":[44],"po.Cardiac":[45],"events":[46,62],"observed":[48],"levels":[51,66,91],"tumor":[53],"necrosis":[54],"factor-\u03b1(TNF-\u03b1),CD40L,P-selectin(Ps)were":[55],"analyzed.Results:There":[56],"no":[58],"difference":[59],"cardiac":[61],"two":[64,72,83],"groups.The":[65],"CD40L,Ps":[68],"TNF-\u03b1":[70],"groups":[73,84],"similar":[75,104],"baseline(P0.05),and":[77],"that":[78],"30d":[79,100],"discharge":[81,102],"significantly":[86],"lower":[87],"than":[88],"before":[89],"PCI(P0.05).The":[90],"TNF-\u03b1,CD40L":[93],"Ps":[95],"simvastatin":[106],"group(P0.05).Conclusion:":[107],"improve":[109],"PCI":[114],"AMI.":[119]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}