{"id":"https://openalex.org/W2369733562","doi":null,"title":"Effects of atorvastatin on lipid profile modification in patients with dyslipoproteinemia","display_name":"Effects of atorvastatin on lipid profile modification in patients with dyslipoproteinemia","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2369733562","mag":"2369733562"},"language":"en","primary_location":{"id":"mag:2369733562","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-YXFY200204005.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764548680","display_name":"Pharmaceutical Care and Research","issn_l":"1671-2838","issn":["1671-2838"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4327896840","host_organization_name":"Publishing House of Pharmaceutical Care and Research","host_organization_lineage":["https://openalex.org/P4327896840"],"host_organization_lineage_names":["Publishing House of Pharmaceutical Care and Research"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceutical Care and Research","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109305343","display_name":"Yong Qin","orcid":"https://orcid.org/0009-0001-1625-8706","observed_orcids":["https://orcid.org/0009-0001-1625-8706"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yong Qin","raw_affiliation_strings":["-Wen, ZHENG Xing"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"-Wen, ZHENG Xing","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5109305343"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.32602147,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atorvastatin","display_name":"atorvastatin","score":1.0},{"id":"https://openalex.org/keywords/pravastatin","display_name":"pravastatin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dyslipoproteinemia","display_name":"dyslipoproteinemia","score":0.9879999756813049},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.8740000128746033},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.7279999852180481},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.9769999980926514},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9610000252723694},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9900000095367432},{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.7170000076293945},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.7580000162124634}],"concepts":[{"id":"https://openalex.org/C2777482532","wikidata":"https://www.wikidata.org/wiki/Q668093","display_name":"Atorvastatin","level":2,"score":0.975798487663269},{"id":"https://openalex.org/C2779519902","wikidata":"https://www.wikidata.org/wiki/Q1240093","display_name":"Pravastatin","level":3,"score":0.9715664982795715},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.6921756267547607},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.6262257099151611},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5516268014907837},{"id":"https://openalex.org/C139572402","wikidata":"https://www.wikidata.org/wiki/Q4927820","display_name":"Blood lipids","level":3,"score":0.541414737701416},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5310224890708923},{"id":"https://openalex.org/C62746215","wikidata":"https://www.wikidata.org/wiki/Q14890615","display_name":"Apolipoprotein B","level":3,"score":0.44105011224746704},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4027024507522583},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40037909150123596},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.38362395763397217}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2369733562","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-YXFY200204005.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764548680","display_name":"Pharmaceutical Care and Research","issn_l":"1671-2838","issn":["1671-2838"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4327896840","host_organization_name":"Publishing House of Pharmaceutical Care and Research","host_organization_lineage":["https://openalex.org/P4327896840"],"host_organization_lineage_names":["Publishing House of Pharmaceutical Care and Research"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceutical Care and Research","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2387486742","https://openalex.org/W2766243369","https://openalex.org/W7220344340","https://openalex.org/W1980049085","https://openalex.org/W2353602320","https://openalex.org/W2377734440","https://openalex.org/W2139241126","https://openalex.org/W2323220010","https://openalex.org/W2377711542","https://openalex.org/W2725588989"],"abstract_inverted_index":{"Objective:":[0],"To":[1],"evaluate":[2],"the":[3,55,58,61,168],"effects":[4,68],"of":[5,63,69,86,89,172],"atorvastatin":[6,26,70,99,119,142],"on":[7,71],"lipid":[8,65,169],"profile":[9,170],"modification":[10,171],"in":[11,98,107,118,126,141,159],"patients":[12,17,160],"with":[13,18,57,113,161],"dyslipoproteinemia.":[14],"Methods:":[15],"Thirth-nine":[16],"dyslipoproteinemia":[19],"were":[20,40,82],"randomly":[21],"divided":[22],"into":[23],"2":[24],"groups,":[25],"group":[27,100,120,128,143],"(n=21,":[28],"10":[29,35],"mg/d,":[30,36],"po)":[31],"and":[32,51,76,91,96,102,105,155],"pravastatin":[33,108,127],"group(n=18,":[34],"po).":[37],"Blood":[38],"samples":[39],"taken":[41],"from":[42],"forearm":[43],"vein":[44],"(after":[45],"fasting":[46],"for":[47,60],"12":[48],"h)":[49],"before":[50,114],"6":[52],"weeks":[53],"after":[54],"treatment":[56],"drugs":[59],"analysis":[62],"serum":[64,73,129],"profile.":[66],"Results:The":[67],"lowering":[72],"total":[74],"cholesterol(TC)":[75],"low":[77],"density":[78,138],"lipoprotein":[79,139],"cholesterol":[80],"(LDL-C)":[81],"similar":[83],"to":[84,167],"those":[85],"pravastatin.The":[87],"concentrations":[88],"TC":[90],"LDL-C":[92],"decreased":[93,133],"by":[94,103,123,134,147],"26.7%":[95],"39.2%":[97],"(P0.01)":[101],"19.4%":[104],"24.2%":[106],"group(P0.01),":[109],"respectively,":[110],"as":[111],"compared":[112],"treatment.":[115],"Serum":[116],"triglyceride(TG)":[117],"was":[121,131,144],"reduced":[122],"25.3%(P0.01),":[124],"but":[125],"TG":[130],"only":[132],"4.1%(P0.05).":[135],"The":[136],"high":[137],"cholesterol(HDL-C)":[140],"remarkably":[145],"increased":[146],"6.4%(P0.05).":[148],"Conclusion:":[149],"Atorvastatin":[150],"could":[151],"greatly":[152],"decrease":[153],"TC,LDL-C":[154],"TG,and":[156],"increase":[157],"HDL-C":[158],"dyslipoproteinemia,and":[162],"can":[163],"be":[164],"effectively":[165],"applied":[166],"these":[173],"patients.":[174]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}