{"id":"https://openalex.org/W2368039737","doi":null,"title":"Role of Overexpressed Proinflammatory Cytokines in the Pathogenesis of Cerebral Palsy","display_name":"Role of Overexpressed Proinflammatory Cytokines in the Pathogenesis of Cerebral Palsy","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W2368039737","mag":"2368039737"},"language":"en","primary_location":{"id":"mag:2368039737","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-ZKLS200602000.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764517539","display_name":"Zhongguo kangfu lilun yu shijian","issn_l":"1006-9771","issn":["1006-9771"],"is_oa":false,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4361729651","host_organization_name":"China Rehabilitation Research Center","host_organization_lineage":["https://openalex.org/P4361729651"],"host_organization_lineage_names":["China Rehabilitation Research Center"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Zhongguo kangfu lilun yu shijian","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102219599","display_name":"Hanyun Yao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Hanyun Yao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5102219599"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.34423787,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11097","display_name":"Cerebral Palsy and Movement Disorders","score":0.014600000344216824,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebral-palsy","display_name":"cerebral palsy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.996999979019165},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9829999804496765},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":1.0},{"id":"https://openalex.org/keywords/hypoxia-ischemia","display_name":"hypoxia-ischemia","score":0.824999988079071},{"id":"https://openalex.org/keywords/perinatal-infection","display_name":"perinatal infection","score":0.996999979019165},{"id":"https://openalex.org/keywords/neonatal-risk-factors","display_name":"neonatal risk factors","score":0.7070000171661377},{"id":"https://openalex.org/keywords/serum-cytokine-levels","display_name":"serum cytokine levels","score":0.8539999723434448},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.7239999771118164}],"concepts":[{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.9691436886787415},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.9098564386367798},{"id":"https://openalex.org/C2779421357","wikidata":"https://www.wikidata.org/wiki/Q210427","display_name":"Cerebral palsy","level":2,"score":0.7622027397155762},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6750070452690125},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.6471730470657349},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.5058507919311523},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5036038756370544},{"id":"https://openalex.org/C74172505","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin","level":3,"score":0.4251718819141388},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3506554365158081},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3140867352485657},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.30019813776016235},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.08033716678619385}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2368039737","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-ZKLS200602000.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764517539","display_name":"Zhongguo kangfu lilun yu shijian","issn_l":"1006-9771","issn":["1006-9771"],"is_oa":false,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4361729651","host_organization_name":"China Rehabilitation Research Center","host_organization_lineage":["https://openalex.org/P4361729651"],"host_organization_lineage_names":["China Rehabilitation Research Center"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Zhongguo kangfu lilun yu shijian","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2325327589","https://openalex.org/W2357678858","https://openalex.org/W3102040266","https://openalex.org/W2044371445","https://openalex.org/W2156394655","https://openalex.org/W2984989497","https://openalex.org/W4295591381","https://openalex.org/W1984526961","https://openalex.org/W4408500141","https://openalex.org/W1967003047"],"abstract_inverted_index":{"ObjectiveTo":[0],"investigate":[1],"the":[2,9,121],"role":[3,119],"of":[4,11,15,25,61,65,79,86,94,123,132],"overexpressed":[5],"proinflammatory":[6,114],"cytokines":[7,115],"in":[8,23,108,120],"pathogenesis":[10,122],"cerebral":[12],"palsy":[13],"(CP).MethodsLevels":[14],"tumor":[16],"necrotic":[17],"factor-\u03b1":[18],"(TNF-\u03b1)":[19],"and":[20,47,63,68,125],"interleukin-6":[21],"(IL-6)":[22],"serum":[24],"31":[26],"CP":[27,37,66,71,87,97,124],"children,":[28],"20":[29,48],"healthy":[30,49,80],"children":[31,67,88],"(as":[32,51],"controls),":[33],"37":[34],"neonates":[35,50,69,95],"with":[36,70,96],"risk":[38,72,98,130],"factors":[39,73,99],"such":[40],"as":[41],"hypoxic-ischemic":[42],"injury":[43],"and/or":[44],"perinatal":[45],"infection,":[46],"controls)":[52],"were":[53,74],"measured":[54],"by":[55],"enzyme-linked":[56],"immunosorbent":[57],"assays":[58],"(ELISA)":[59],"retrospectively.ResultsLevels":[60],"TNF-\u03b1":[62,84],"IL-6":[64,109],"significantly":[75,90],"higher":[76,91],"than":[77,92],"that":[78,93],"controls":[81],"(":[82,100],"P0.05).":[83],"level":[85,110],"was":[89,104],"P0.05),":[101],"but":[102],"there":[103],"no":[105],"significant":[106],"difference":[107],"between":[111],"two":[112],"groups.ConclusionOverexpressed":[113],"play":[116],"an":[117,128],"important":[118],"may":[126],"be":[127],"independent":[129],"factor":[131],"CP.":[133]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}