{"id":"https://openalex.org/W23675742","doi":null,"title":"[Research progress in sperm mediated gene transfer technology].","display_name":"[Research progress in sperm mediated gene transfer technology].","publication_year":2013,"publication_date":"2013-04-01","ids":{"openalex":"https://openalex.org/W23675742","mag":"23675742","pmid":"https://pubmed.ncbi.nlm.nih.gov/23858777"},"language":"zh","primary_location":{"id":"pmid:23858777","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23858777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043747261","display_name":"Xiaoxiong Hao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoxiong Hao","raw_affiliation_strings":["Company Four, Third Military Medical University, Chongqing 400038, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Company Four, Third Military Medical University, Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zheng Zhu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zheng Zhu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054637200","display_name":"Mianfu Cao","orcid":"https://orcid.org/0000-0001-6687-9917","observed_orcids":["https://orcid.org/0000-0001-6687-9917"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mianfu Cao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074350974","display_name":"Chengren Li","orcid":"https://orcid.org/0000-0003-1014-6604","observed_orcids":["https://orcid.org/0000-0003-1014-6604"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chengren Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5033214492","display_name":"Yunlai Lin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yunlai Lin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00217192,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"30","issue":"2","first_page":"443","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sperm-mediated-gene-transfer","display_name":"sperm-mediated gene transfer","score":0.9549999833106995},{"id":"https://openalex.org/keywords/genetically-modified-animals","display_name":"transgenic animals","score":0.9120000004768372},{"id":"https://openalex.org/keywords/transgenesis","display_name":"transgenesis","score":0.7820000052452087},{"id":"https://openalex.org/keywords/gene-transfer-mechanisms","display_name":"gene transfer mechanisms","score":0.6290000081062317},{"id":"https://openalex.org/keywords/transgenic-animal-production","display_name":"transgenic animal production","score":0.6000000238418579}],"concepts":[{"id":"https://openalex.org/C3018928802","wikidata":"https://www.wikidata.org/wiki/Q83185","display_name":"Gene transfer","level":3,"score":0.6457846760749817},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.5277809500694275},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.5226735472679138},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48990243673324585},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.4828684628009796},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.45703187584877014},{"id":"https://openalex.org/C2993926007","wikidata":"https://www.wikidata.org/wiki/Q159236","display_name":"Gene technology","level":2,"score":0.43513181805610657},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4173804819583893},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.404531329870224},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.36489999294281006},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32646894454956055}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005818","descriptor_name":"Genetic Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013083","descriptor_name":"Sperm Transport","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030801","descriptor_name":"Animals, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:23858777","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23858777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi","raw_type":"English Abstract"},{"id":"mag:23675742","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23858777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1751541356","https://openalex.org/W1914710014","https://openalex.org/W1963821266","https://openalex.org/W1965139875","https://openalex.org/W1982823894","https://openalex.org/W2016646606","https://openalex.org/W2020267609","https://openalex.org/W2028955606","https://openalex.org/W2045590599","https://openalex.org/W2073613701","https://openalex.org/W2074819424","https://openalex.org/W2075520007","https://openalex.org/W2077464591","https://openalex.org/W2078741928","https://openalex.org/W2091801540","https://openalex.org/W2112247834","https://openalex.org/W2116360632","https://openalex.org/W2121051228","https://openalex.org/W2121535401","https://openalex.org/W2122199148","https://openalex.org/W2141914495","https://openalex.org/W2145730981","https://openalex.org/W2146094308","https://openalex.org/W2163202048","https://openalex.org/W2163589808","https://openalex.org/W2789732774","https://openalex.org/W4212961339"],"related_works":["https://openalex.org/W2356342521","https://openalex.org/W2140896766","https://openalex.org/W2161999626","https://openalex.org/W2369544858","https://openalex.org/W2128774058","https://openalex.org/W128438529","https://openalex.org/W2107769832","https://openalex.org/W2737110218","https://openalex.org/W2313760871","https://openalex.org/W4238626494"],"abstract_inverted_index":{"With":[0],"the":[1,9,24,59,63,72],"rapid":[2],"development":[3],"of":[4,11,26,79],"biotechnology,":[5],"we":[6,70],"can":[7],"change":[8],"trait":[10],"organism":[12],"using":[13],"transgenetic":[14,47,65],"technology.":[15],"In":[16,67],"recent":[17],"years,":[18],"there":[19],"are":[20],"growing":[21],"interests":[22],"in":[23,52],"establishment":[25],"sperm":[27],"mediated":[28],"gene":[29],"transfer":[30],"(SMGT)":[31],"technology":[32,44],"as":[33],"an":[34],"effective":[35],"and":[36,54,77],"convenient":[37],"method":[38],"to":[39,58],"produce":[40],"transgenic":[41],"animals.":[42],"SMGT":[43],"is":[45,50],"a":[46],"method,":[48],"which":[49],"easy":[51],"operation":[53,76],"does":[55],"little":[56],"harm":[57],"cell":[60],"compared":[61],"with":[62],"other":[64],"methods.":[66],"this":[68],"review,":[69],"expound":[71],"background,":[73],"development,":[74],"mechanism,":[75],"application":[78],"SMGT.":[80]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}