{"id":"https://openalex.org/W2367009105","doi":null,"title":"Analysis of chromosome abnormities in 3 156 patients with reproduction abnormalities","display_name":"Analysis of chromosome abnormities in 3 156 patients with reproduction abnormalities","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2367009105","mag":"2367009105"},"language":"en","primary_location":{"id":"mag:2367009105","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-JHFC201504010.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764626102","display_name":"Chinese Journal of Family Planning & Gynecotokology","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chinese Journal of Family Planning & Gynecotokology","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100741518","display_name":"Chu Chen","orcid":"https://orcid.org/0000-0003-2267-8050","observed_orcids":["https://orcid.org/0000-0003-2267-8050","https://orcid.org/0000-0002-8952-573X"]},"institutions":[{"id":"https://openalex.org/I4210125143","display_name":"Chengdu University","ror":"https://ror.org/034z67559","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210125143"]},{"id":"https://openalex.org/I53411278","display_name":"Chengdu University of Traditional Chinese Medicine","ror":"https://ror.org/00pcrz470","country_code":"CN","type":"education","lineage":["https://openalex.org/I53411278"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chu Chen","raw_affiliation_strings":["The Second Medical College of Chengdu University of TCM"],"raw_orcid":"https://orcid.org/0000-0003-2267-8050","affiliations":[{"raw_affiliation_string":"The Second Medical College of Chengdu University of TCM","institution_ids":["https://openalex.org/I4210125143","https://openalex.org/I53411278"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100741518"],"corresponding_institution_ids":["https://openalex.org/I4210125143","https://openalex.org/I53411278"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.16614468,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.4011000096797943,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.4011000096797943,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":0.21469999849796295,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.2085999995470047,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chromosomal-abnormalities","display_name":"chromosomal abnormalities","score":0.8389999866485596},{"id":"https://openalex.org/keywords/reproductive-abnormalities","display_name":"reproductive abnormalities","score":0.9309999942779541},{"id":"https://openalex.org/keywords/karyotype","display_name":"karyotype","score":0.6890000104904175},{"id":"https://openalex.org/keywords/sex-chromosome-aneuploidy","display_name":"sex chromosome aneuploidy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/robertsonian-translocation","display_name":"Robertsonian translocation","score":0.8989999890327454},{"id":"https://openalex.org/keywords/miscarriage","display_name":"miscarriage","score":0.9290000200271606},{"id":"https://openalex.org/keywords/infertility","display_name":"infertility","score":0.9919999837875366},{"id":"https://openalex.org/keywords/fetal-malformations","display_name":"fetal malformations","score":0.9470000267028809},{"id":"https://openalex.org/keywords/congenital-malformations","display_name":"congenital malformations","score":0.925000011920929}],"concepts":[{"id":"https://openalex.org/C138626823","wikidata":"https://www.wikidata.org/wiki/Q916504","display_name":"Chromosomal translocation","level":3,"score":0.811486005783081},{"id":"https://openalex.org/C2779245376","wikidata":"https://www.wikidata.org/wiki/Q28693","display_name":"Miscarriage","level":3,"score":0.7834203839302063},{"id":"https://openalex.org/C53226629","wikidata":"https://www.wikidata.org/wiki/Q189967","display_name":"Karyotype","level":4,"score":0.7606174945831299},{"id":"https://openalex.org/C2780458022","wikidata":"https://www.wikidata.org/wiki/Q2914875","display_name":"Robertsonian translocation","level":5,"score":0.6804532408714294},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.6503111124038696},{"id":"https://openalex.org/C59659247","wikidata":"https://www.wikidata.org/wiki/Q11990","display_name":"Reproduction","level":2,"score":0.5994441509246826},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.5675497055053711},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5490574836730957},{"id":"https://openalex.org/C2779672484","wikidata":"https://www.wikidata.org/wiki/Q529622","display_name":"Aneuploidy","level":4,"score":0.4910695552825928},{"id":"https://openalex.org/C50965678","wikidata":"https://www.wikidata.org/wiki/Q2724302","display_name":"Abnormality","level":2,"score":0.49045559763908386},{"id":"https://openalex.org/C2780189214","wikidata":"https://www.wikidata.org/wiki/Q744962","display_name":"Chromosome abnormality","level":5,"score":0.4378896951675415},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.42829272150993347},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4197949767112732},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.329863578081131},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2899274230003357},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.27621209621429443},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2367009105","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-JHFC201504010.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764626102","display_name":"Chinese Journal of Family Planning & Gynecotokology","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chinese Journal of Family Planning & Gynecotokology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2366952443","https://openalex.org/W2381975964","https://openalex.org/W2381290427","https://openalex.org/W2353740048","https://openalex.org/W2363997922","https://openalex.org/W2355422114","https://openalex.org/W2357405540","https://openalex.org/W2375923502","https://openalex.org/W2352597268","https://openalex.org/W1518841066"],"abstract_inverted_index":{"Objective":[0],"To":[1],"discuss":[2],"the":[3,43,68,94],"relationship":[4],"between":[5],"reproduction":[6,22,48],"abnormality":[7],"and":[8,14,28,103],"chromosome":[9,78,90,125,137],"abnormity.":[10],"Methods":[11],"Chromosome":[12],"karyotypes":[13,53],"clinical":[15,95],"data":[16],"of":[17,51,58,70,100],"3":[18,44],"156":[19,45],"patients":[20,46,131],"with":[21,47,124,132],"abnormalities":[23,121,134],"in":[24],"Sichuan":[25],"Provincial":[26],"Maternity":[27],"Child":[29],"Health":[30],"Hospital":[31],"from":[32],"Aug":[33,36],"2008":[34],"to":[35,93,135],"2014":[37],"were":[38,54,67,76,88,106],"retrospectively":[39],"analyzed.":[40],"Results":[41],"Among":[42],"abnormalities,82":[49],"cases":[50],"abnormal":[52],"detected,The":[55],"incidence":[56],"rate":[57,99],"chromosomal":[59,97],"abnormity":[60,98],"was":[61],"2.":[62],"6%,30":[63],"cases(":[64,73,80,85],"36.":[65],"59%)":[66],"balance":[69],"autosomal":[71],"translocation,28":[72],"34.":[74],"15%)":[75],"sex":[77],"aneuploidy,12":[79],"14.":[81,86],"63%)were":[82],"robertsonian":[83],"translocation,12":[84],"63%)":[87],"other":[89],"abnormities.":[91,126],"As":[92],"manifestations,the":[96],"miscarriage,infertility,fetal":[101],"malformation":[102],"birth":[104],"defect":[105],"3.":[107],"26%(":[108],"53":[109],"/1":[110],"625),2.":[111],"02%(":[112],"25":[113],"/1235),1.":[114],"35%(":[115],"4":[116],"/296)":[117],"respectively.":[118],"Conclusion":[119],"Reproductive":[120],"are":[122],"associated":[123],"It":[127],"is":[128],"necessary":[129],"for":[130],"reproductive":[133],"take":[136],"examination.":[138]},"counts_by_year":[],"updated_date":"2026-10-07T09:51:55.459714","created_date":"2016-06-24T00:00:00"}