{"id":"https://openalex.org/W2365599110","doi":null,"title":"Multigenerational depression and anxiety influence maternal measures of stress during pregnancy","display_name":"Multigenerational depression and anxiety influence maternal measures of stress during pregnancy","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2365599110","mag":"2365599110"},"language":"en","primary_location":{"id":"pmh:oai:cuscholar:ng451j120","doi":null,"is_oa":true,"landing_page_url":"https://scholar.colorado.edu/concern/undergraduate_honors_theses/ng451j120","pdf_url":"https://scholar.colorado.edu/downloads/h128nf146","source":{"id":"https://openalex.org/S4306401957","display_name":"CU Scholar (University of Colorado Boulder)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I188538660","host_organization_name":"University of Colorado Boulder","host_organization_lineage":["https://openalex.org/I188538660"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Undergraduate Honors Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://scholar.colorado.edu/downloads/h128nf146","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024985344","display_name":"Jessica Smith","orcid":"https://orcid.org/0009-0003-5050-1487","observed_orcids":["https://orcid.org/0009-0003-5050-1487","https://orcid.org/0009-0001-7810-7356","https://orcid.org/0009-0009-4304-3899"]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jessica Smith","raw_affiliation_strings":["University of Colorado Boulder"],"raw_orcid":"https://orcid.org/0009-0003-5050-1487","affiliations":[{"raw_affiliation_string":"University of Colorado Boulder","institution_ids":["https://openalex.org/I188538660"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5024985344"],"corresponding_institution_ids":["https://openalex.org/I188538660"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10182","display_name":"Child and Adolescent Psychosocial and Emotional Development","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antenatal-depression","display_name":"antenatal depression","score":0.7459999918937683},{"id":"https://openalex.org/keywords/maternal-anxiety","display_name":"maternal anxiety","score":0.6179999709129333},{"id":"https://openalex.org/keywords/family-history-of-mental-illness","display_name":"family history of mental illness","score":0.8320000171661377},{"id":"https://openalex.org/keywords/multigenerational-transmission","display_name":"multigenerational transmission","score":0.7160000205039978},{"id":"https://openalex.org/keywords/maternal-grandmother","display_name":"maternal grandmother","score":0.6740000247955322},{"id":"https://openalex.org/keywords/maternal-stress","display_name":"maternal stress","score":0.4339999854564667},{"id":"https://openalex.org/keywords/hair-cortisol","display_name":"hair cortisol","score":0.652999997138977},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.8080000281333923},{"id":"https://openalex.org/keywords/postpartum-depression","display_name":"postpartum depression","score":0.7570000290870667},{"id":"https://openalex.org/keywords/prenatal-stress","display_name":"prenatal stress","score":0.3880000114440918},{"id":"https://openalex.org/keywords/maternal-mood-disorders","display_name":"maternal mood disorders","score":0.4659999907016754},{"id":"https://openalex.org/keywords/neonatal-cortisol","display_name":"neonatal cortisol","score":0.5699999928474426},{"id":"https://openalex.org/keywords/posttraumatic-stress-disorder","display_name":"post-traumatic stress disorder","score":0.5899999737739563},{"id":"https://openalex.org/keywords/anxiety-disorders-in-pregnancy","display_name":"anxiety disorders in pregnancy","score":0.6010000109672546},{"id":"https://openalex.org/keywords/adverse-birth-outcomes","display_name":"adverse birth outcomes","score":0.5580000281333923},{"id":"https://openalex.org/keywords/early-childhood-outcomes","display_name":"early childhood outcomes","score":0.8650000095367432}],"concepts":[{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.7293475866317749},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6118382215499878},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5827507972717285},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5582637190818787},{"id":"https://openalex.org/C21036866","wikidata":"https://www.wikidata.org/wiki/Q181767","display_name":"Stress (linguistics)","level":2,"score":0.5234198570251465},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4917967617511749},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.448022723197937},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3259398937225342},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:cuscholar:ng451j120","doi":null,"is_oa":true,"landing_page_url":"https://scholar.colorado.edu/concern/undergraduate_honors_theses/ng451j120","pdf_url":"https://scholar.colorado.edu/downloads/h128nf146","source":{"id":"https://openalex.org/S4306401957","display_name":"CU Scholar (University of Colorado Boulder)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I188538660","host_organization_name":"University of Colorado Boulder","host_organization_lineage":["https://openalex.org/I188538660"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Undergraduate Honors Thesis"},{"id":"pmh:oai:scholar.colorado.edu:honr_theses-2269","doi":null,"is_oa":false,"landing_page_url":"https://scholar.colorado.edu/honr_theses/1148","pdf_url":null,"source":{"id":"https://openalex.org/S4306401957","display_name":"CU Scholar (University of Colorado Boulder)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I188538660","host_organization_name":"University of Colorado Boulder","host_organization_lineage":["https://openalex.org/I188538660"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Undergraduate Honors Theses","raw_type":"text"},{"id":"mag:2365599110","doi":null,"is_oa":false,"landing_page_url":"https://scholar.colorado.edu/honr_theses/1148/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:cuscholar:ng451j120","doi":null,"is_oa":true,"landing_page_url":"https://scholar.colorado.edu/concern/undergraduate_honors_theses/ng451j120","pdf_url":"https://scholar.colorado.edu/downloads/h128nf146","source":{"id":"https://openalex.org/S4306401957","display_name":"CU Scholar (University of Colorado Boulder)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I188538660","host_organization_name":"University of Colorado Boulder","host_organization_lineage":["https://openalex.org/I188538660"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Undergraduate Honors Thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1572355645","display_name":"Basic to Clinical Molecular Neurobiology of Nicotinic Receptors in Schizophrenia","funder_award_id":"P50MH086383","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337868","display_name":"University of Colorado School of Medicine, Anschutz Medical Campus","ror":"https://ror.org/03wmf1y16"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2365599110.pdf","grobid_xml":"https://content.openalex.org/works/W2365599110.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W104415939","https://openalex.org/W1829844494","https://openalex.org/W1978611831","https://openalex.org/W1979423658","https://openalex.org/W1990652217","https://openalex.org/W2007123434","https://openalex.org/W2040975346","https://openalex.org/W2042170262","https://openalex.org/W2042221209","https://openalex.org/W2043227319","https://openalex.org/W2057461494","https://openalex.org/W2066276157","https://openalex.org/W2066894859","https://openalex.org/W2080452647","https://openalex.org/W2082327542","https://openalex.org/W2082387412","https://openalex.org/W2092670527","https://openalex.org/W2100800628","https://openalex.org/W2104625788","https://openalex.org/W2105188889","https://openalex.org/W2123339815","https://openalex.org/W2150734066","https://openalex.org/W2157406479","https://openalex.org/W2259216925"],"related_works":["https://openalex.org/W1990165587","https://openalex.org/W4390755397","https://openalex.org/W2945906976","https://openalex.org/W2965158495","https://openalex.org/W4317952030","https://openalex.org/W2965301323","https://openalex.org/W1983035109","https://openalex.org/W4405614757","https://openalex.org/W2788557028","https://openalex.org/W2514831737"],"abstract_inverted_index":{"Objective:":[0],"The":[1,57],"strongest":[2],"risk":[3],"factor":[4],"for":[5,142,189,216,257,267,274,278,292,328,332],"depression":[6,15,99,223,337,379,385,417],"during":[7,18,51,194,420],"pregnancy":[8,19,52],"is":[9,31,365],"a":[10,32,66,95,122,169,185,195,220,295],"history":[11,67,97,124,178,234,296,312,335,383,406],"of":[12,42,47,59,68,98,125,145,179,201,235,297,313,336,358,384,407,416],"depression,":[13],"and":[14,16,26,53,93,105,131,136,149,203,213,244,247,249,276,289,317,319,330,373,380,414,418,422],"anxiety":[17,74,101,204,225,280,300,339,361,387,419],"can":[20],"lead":[21],"to":[22,63,119,307,410],"adverse":[23],"maternal,":[24],"birth,":[25],"early":[27],"childhood":[28],"outcomes.":[29],"There":[30],"research":[33,61],"gap":[34],"in":[35,75,89,168,262,301,340,362,388,397],"multigenerational":[36],"studies":[37],"that":[38,375],"examine":[39],"the":[40,45,54,76,85,90,140,150,208,263,302,324,341,363,371,389,393,398],"influence":[41],"heredity":[43],"on":[44,139,370],"development":[46],"maternal":[48,104,130,137,248,348,368],"mood":[49],"disorders":[50],"postpartum":[55,423],"period.":[56],"purpose":[58],"our":[60],"was":[62,182,240,253,343],"determine":[64,120],"if":[65,94,121],"major":[69,161],"depressive":[70],"disorder":[71,281],"(MDD)":[72],"and/or":[73,100,224,299,338,360,386],"pregnant":[77,91,399],"woman\u2019s":[78],"mother":[79],"(maternal":[80],"grandmother,":[81],"or":[82,163],"MGM)":[83],"predicts":[84,392],"same":[86,394],"psychiatric":[87,126,162,180,210,236,314,395,408],"illness":[88,127,181,315,396,409],"woman":[92],"family":[96,123,233,311,405],"correlates":[102,128],"with":[103,129,207,222,228,294,309,323,347,367,378],"fetal":[106,132,250],"hypothalamic-pituitary-adrenocortical":[107],"(HPA)":[108],"axis":[109,350],"function,":[110],"as":[111,284,352],"represented":[112,353],"by":[113,286,354],"hair":[114,133,239,252,355],"cortisol.":[115],"We":[116],"also":[117,391],"sought":[118],"cortisol":[134,258],"concentration":[135],"scores":[138,215,291,321,369],"Center":[141],"Epidemiological":[143],"Studies":[144],"Depression":[146],"Scale":[147],"(CES-D)":[148],"State-Trait":[151],"Anxiety":[152],"Inventory":[153],"(STAI).\\nMethods:":[154],"Pregnant":[155],"participants":[156,217,229,261,293,308],"\u226518":[157],"years":[158],"old":[159],"without":[160],"physical":[164],"comorbidities":[165],"were":[166,205,226,304],"enrolled":[167],"prospective":[170],"longitudinal":[171],"study":[172,197,264],"at":[173,242],"\u226415":[174],"weeks":[175,246],"gestation.":[176],"Family":[177],"abstracted":[183],"from":[184],"Structured":[186],"Clinical":[187],"Interview":[188],"DSM-IV":[190],"Disorders":[191],"(SCID),":[192],"conducted":[193],"scheduled":[196],"visit.":[198],"Maternal":[199,238],"diagnoses":[200],"MDD":[202,275,298,329,359],"compared":[206,227,306],"MGM\u2019s":[209],"history.":[211],"CES-D":[212,288,372],"STAI":[214,290,331,374],"who":[218,230],"had":[219,231,265],"MGM":[221,303,342,364,390],"no":[232,310],"illness.":[237],"collected":[241,254],"16":[243],"28":[245],"(neonatal)":[251],"following":[255],"delivery":[256],"analysis.\\nResults:":[259],"153":[260],"data":[266],"analysis.":[268],"Of":[269],"these,":[270],"40%":[271],"met":[272],"criteria":[273],"24%":[277],"an":[279],"(including":[282],"PTSD)":[283],"determined":[285],"SCID.":[287],"higher":[305],"(p=0.02":[316],"p=0.005),":[318],"these":[320],"corresponded":[322],"respective":[325],"scales":[326],"(CES-D":[327],"anxiety).":[333],"A":[334,382],"not":[344],"significantly":[345],"correlated":[346],"HPA":[349],"function":[351],"cortisol.\\nConclusion:":[356],"History":[357],"associated":[366],"are":[376],"consistent":[377],"anxiety.":[381],"participant.":[400],"Healthcare":[401],"providers":[402],"must":[403],"consider":[404],"improve":[411],"recognition,":[412],"diagnosis,":[413],"treatment":[415],"prenatal":[421],"care.":[424]},"counts_by_year":[],"updated_date":"2026-10-15T10:00:46.086208","created_date":"2016-06-24T00:00:00"}