{"id":"https://openalex.org/W2363201989","doi":null,"title":"[Protective effect of RenShen compound and DanHuang compound on muscle atrophy in suspended rats].","display_name":"[Protective effect of RenShen compound and DanHuang compound on muscle atrophy in suspended rats].","publication_year":1999,"publication_date":"1999-08-01","ids":{"openalex":"https://openalex.org/W2363201989","mag":"2363201989","pmid":"https://pubmed.ncbi.nlm.nih.gov/11542712"},"language":"zh","primary_location":{"id":"pmid:11542712","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11542712","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100935818","display_name":"Y L Ma","orcid":"https://orcid.org/0000-0001-8270-7365","observed_orcids":["https://orcid.org/0000-0001-8270-7365"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y L Ma","raw_affiliation_strings":["Institute of Space Medico-Engineering, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Space Medico-Engineering, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083157964","display_name":"Sun Yz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Z Sun","raw_affiliation_strings":["zhi,YANG Hong  hui"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"zhi,YANG Hong  hui","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110401661","display_name":"Yang Hh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H H Yang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.25911119,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"12","issue":"4","first_page":"281","last_page":"3"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.8511000275611877,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.8511000275611877,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.1459999978542328,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/muscle-atrophy","display_name":"muscle atrophy","score":0.9789999723434448},{"id":"https://openalex.org/keywords/simulated-microgravity","display_name":"simulated microgravity","score":0.824999988079071},{"id":"https://openalex.org/keywords/tail-suspension-test","display_name":"tail suspension test","score":0.9430000185966492},{"id":"https://openalex.org/keywords/soleus-muscle","display_name":"soleus muscle","score":0.9049999713897705},{"id":"https://openalex.org/keywords/gastrocnemius-muscle","display_name":"gastrocnemius","score":0.9950000047683716},{"id":"https://openalex.org/keywords/cross-sectional-area","display_name":"cross-sectional area","score":0.8220000267028809},{"id":"https://openalex.org/keywords/sarcomere-ultrastructure","display_name":"sarcomere ultrastructure","score":0.9440000057220459},{"id":"https://openalex.org/keywords/traditional-chinese-medicine","display_name":"traditional Chinese medicine","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C2781172350","wikidata":"https://www.wikidata.org/wiki/Q194520","display_name":"Atrophy","level":2,"score":0.7403872013092041},{"id":"https://openalex.org/C2776263037","wikidata":"https://www.wikidata.org/wiki/Q1557686","display_name":"Muscle atrophy","level":3,"score":0.643688976764679},{"id":"https://openalex.org/C68731436","wikidata":"https://www.wikidata.org/wiki/Q1337087","display_name":"Sarcomere","level":3,"score":0.4961429536342621},{"id":"https://openalex.org/C87555872","wikidata":"https://www.wikidata.org/wiki/Q3141316","display_name":"Ultrastructure","level":2,"score":0.49318426847457886},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4785221815109253},{"id":"https://openalex.org/C2776104385","wikidata":"https://www.wikidata.org/wiki/Q1954164","display_name":"Soleus muscle","level":3,"score":0.4625595808029175},{"id":"https://openalex.org/C105341887","wikidata":"https://www.wikidata.org/wiki/Q1307987","display_name":"Suspension (topology)","level":3,"score":0.4583437442779541},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4421165883541107},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4333254098892212},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.38265901803970337},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3269730508327484},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.19168367981910706},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.09937217831611633},{"id":"https://openalex.org/C5961521","wikidata":"https://www.wikidata.org/wiki/Q746083","display_name":"Homotopy","level":2,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004353","descriptor_name":"Drug Evaluation, Preclinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005894","descriptor_name":"Panax","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009133","descriptor_name":"Muscular Atrophy","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009133","descriptor_name":"Muscular Atrophy","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D010946","descriptor_name":"Plants, Medicinal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012518","descriptor_name":"Sarcomeres","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018474","descriptor_name":"Weightlessness Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D018657","descriptor_name":"Muscle Fibers, Slow-Twitch","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D019417","descriptor_name":"Hindlimb Suspension","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D019417","descriptor_name":"Hindlimb Suspension","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:11542712","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11542712","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering","raw_type":"English Abstract"},{"id":"mag:2363201989","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11542712","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2349555069","https://openalex.org/W2065581195","https://openalex.org/W2358396195","https://openalex.org/W2408620610","https://openalex.org/W2078390743","https://openalex.org/W2363382669","https://openalex.org/W3177000929","https://openalex.org/W2956113015","https://openalex.org/W2215795735","https://openalex.org/W2364646724"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"study":[2],"the":[3,50],"protective":[4],"effect":[5],"of":[6,27,31,49,55,59,87,103,106,123],"RenShen":[7,62],"compound":[8,11],"and":[9,23,29,34,65,77,85,108,128,139],"DanHuang":[10,66],"on":[12],"muscle":[13,104,145],"atrophy":[14,146],"caused":[15,147],"by":[16,70,148],"simulated":[17],"weightlessness":[18],"in":[19,39,61,110,115,126],"rats.":[20],"METHOD:":[21],"Percentage":[22],"cross":[24],"sectional":[25,101],"area":[26,102],"fibers":[28,105],"ultrastructure":[30],"soleus":[32],"(SOL)":[33],"gastrocnemius":[35],"(GAS)":[36],"were":[37],"determined":[38],"30":[40],"d":[41],"tail":[42,149],"suspended":[43],"rats":[44],"with":[45,96,135],"or":[46],"without":[47],"administration":[48],"medicine.":[51],"RESULT:":[52],"The":[53,121],"percentage":[54],"type":[56],"I":[57],"fiber":[58],"SOL":[60,107,124],"(RS)":[63],"group":[64,68,117],"(DH)":[67],"increased":[69],"(13.5":[71],"+/-":[72,79],"0.96)%":[73],"(P":[74,81,118],"<":[75,82,119],"0.05)":[76,83],"(11.2":[78],"0.84)%":[80],"respectively,":[84],"those":[86],"GAS":[88,109],"showed":[89],"only":[90],"an":[91],"increasing":[92],"trend":[93],"as":[94,133],"compared":[95,134],"suspension":[97],"control":[98],"(SC).":[99],"Cross":[100],"both":[111],"groups":[112,130],"increased,":[113],"especially":[114],"RS":[116,127,138],"0.05).":[120],"construction":[122],"sarcomere":[125],"DH":[129,140],"was":[131],"improved":[132],"SC.":[136],"CONCLUSION:":[137],"compounds":[141],"can":[142],"partially":[143],"prevent":[144],"suspension.":[150]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}