{"id":"https://openalex.org/W2362370673","doi":null,"title":"Inhibition effects of cyhalothrin on the delayed rectifier potassium current in the central neurons of Helicoverpa armigera","display_name":"Inhibition effects of cyhalothrin on the delayed rectifier potassium current in the central neurons of Helicoverpa armigera","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W2362370673","mag":"2362370673"},"language":"en","primary_location":{"id":"mag:2362370673","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-KCXB200602010.htm","pdf_url":null,"source":{"id":"https://openalex.org/S4306500326","display_name":"Acta Entomologica Sinica","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Acta Entomologica Sinica","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039902970","display_name":"Bing He","orcid":"https://orcid.org/0000-0002-8564-0933","observed_orcids":["https://orcid.org/0000-0002-8564-0933"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Bing He","raw_affiliation_strings":["-Jun*, WU Chun-Lin, LIU An-Xi"],"raw_orcid":"https://orcid.org/0000-0002-8564-0933","affiliations":[{"raw_affiliation_string":"-Jun*, WU Chun-Lin, LIU An-Xi","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5039902970"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.19576637,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11075","display_name":"Insect Resistance and Genetics","score":0.6029999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11075","display_name":"Insect Resistance and Genetics","score":0.6029999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.19290000200271606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.040800001472234726,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyhalothrin","display_name":"cyhalothrin","score":1.0},{"id":"https://openalex.org/keywords/pyrethroid-insecticides","display_name":"pyrethroid insecticides","score":0.9580000042915344},{"id":"https://openalex.org/keywords/delayed-rectifier-potassium-current","display_name":"delayed rectifier potassium current","score":0.9929999709129333},{"id":"https://openalex.org/keywords/potassium-channels","display_name":"potassium channels","score":0.7789999842643738},{"id":"https://openalex.org/keywords/helicoverpa-armigera","display_name":"Helicoverpa armigera","score":0.9959999918937683},{"id":"https://openalex.org/keywords/central-nervous-system-neurons","display_name":"central nervous system neurons","score":0.9070000052452087},{"id":"https://openalex.org/keywords/insect-neurotoxicity","display_name":"insect neurotoxicity","score":0.7400000095367432},{"id":"https://openalex.org/keywords/action-potential-threshold","display_name":"action potential threshold","score":0.5199999809265137},{"id":"https://openalex.org/keywords/insecticide-target-sites","display_name":"insecticide target sites","score":0.49300000071525574}],"concepts":[{"id":"https://openalex.org/C2778727878","wikidata":"https://www.wikidata.org/wiki/Q421593","display_name":"Cyhalothrin","level":3,"score":0.9599957466125488},{"id":"https://openalex.org/C2776712339","wikidata":"https://www.wikidata.org/wiki/Q811652","display_name":"Helicoverpa armigera","level":3,"score":0.8972504734992981},{"id":"https://openalex.org/C2776035571","wikidata":"https://www.wikidata.org/wiki/Q745766","display_name":"Pyrethroid","level":3,"score":0.7366889119148254},{"id":"https://openalex.org/C517785266","wikidata":"https://www.wikidata.org/wiki/Q703","display_name":"Potassium","level":2,"score":0.6942846775054932},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.576882541179657},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.48181217908859253},{"id":"https://openalex.org/C147944092","wikidata":"https://www.wikidata.org/wiki/Q176366","display_name":"Patch clamp","level":3,"score":0.4803839325904846},{"id":"https://openalex.org/C94924445","wikidata":"https://www.wikidata.org/wiki/Q841456","display_name":"Inward-rectifier potassium ion channel","level":4,"score":0.42159345746040344},{"id":"https://openalex.org/C83743174","wikidata":"https://www.wikidata.org/wiki/Q423778","display_name":"Potassium channel","level":2,"score":0.41902121901512146},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.40047594904899597},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3635484576225281},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3608318567276001},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.32606688141822815},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19948291778564453},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.16799446940422058},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16752728819847107},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.1567617952823639},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.10683363676071167},{"id":"https://openalex.org/C50254741","wikidata":"https://www.wikidata.org/wiki/Q62536","display_name":"Ion channel","level":3,"score":0.08775267004966736},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.0626814067363739},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2362370673","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-KCXB200602010.htm","pdf_url":null,"source":{"id":"https://openalex.org/S4306500326","display_name":"Acta Entomologica Sinica","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Acta Entomologica Sinica","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2001238178","https://openalex.org/W2373150476","https://openalex.org/W4388666074","https://openalex.org/W2386004633","https://openalex.org/W3142621187","https://openalex.org/W1963652055","https://openalex.org/W7095767132","https://openalex.org/W4401325831","https://openalex.org/W2162961699","https://openalex.org/W2008861356"],"abstract_inverted_index":{"The":[0,28,69],"effects":[1],"of":[2,14,34,71,78,103,124,151,160],"cyhalothrin":[3,52,79],"on":[4],"the":[5,11,20,25,72,81,91,97,101,108,117,122,126,145,157],"delayed":[6],"rectifier":[7],"potassium":[8,127,149],"current":[9,73,135],"in":[10,86],"central":[12,154],"neurons":[13,155],"Helicoverpa":[15,152],"armigera":[16,153],"were":[17,40,61],"studied":[18],"using":[19],"patch":[21],"clamp":[22],"technique":[23],"for":[24],"first":[26],"time.":[27],"results":[29,118],"showed":[30],"that":[31,120],"before":[32],"application":[33,77],"cyhalothrin,":[35,125],"81%":[36],"and":[37,58,80,100,134,148],"39%":[38],"cells":[39,60],"activated":[41,62,131],"at-30":[42],"mV":[43,45,64,66],"and-40":[44],"(n=21),":[46],"respectively.":[47,68],"In":[48,115],"15":[49],"min":[50,88],"after":[51,76],"(10":[53],"-5":[54],"mmol/L)":[55],"application,":[56,92],"63%":[57],"38%":[59],"at-40":[63],"and-50":[65],"(n=8),":[67],"amplitude":[70,136],"decreased":[74],"significantly":[75],"inhibition":[82],"percentage":[83],"reached":[84],"37.7%":[85],"1":[87],"(n=19).":[89],"After":[90],"activation":[93],"curve":[94],"shifted":[95],"to":[96,144],"negative":[98],"direction":[99],"value":[102,110],"V_h":[104],"changed":[105],"significantly,":[106,140],"but":[107],"k":[109],"did":[111],"not":[112],"change":[113],"remarkably.":[114],"conclusion,":[116],"suggest":[119],"under":[121],"action":[123,158],"channels":[128,150],"can":[129,137],"be":[130,138],"more":[132],"easily":[133],"inhibited":[139],"this":[141],"is":[142],"related":[143],"nervous":[146],"insensitivity,":[147],"are":[156],"targets":[159],"pyrethroid":[161],"insecticides.":[162]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}