{"id":"https://openalex.org/W2361744600","doi":null,"title":"Weekly administration of docetaxel and oxaliplatin combined with 5-FU+LV for advanced gastric cancer","display_name":"Weekly administration of docetaxel and oxaliplatin combined with 5-FU+LV for advanced gastric cancer","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2361744600","mag":"2361744600"},"language":"en","primary_location":{"id":"mag:2361744600","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-SXZL200801035.htm","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Modern Oncology","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Qian Chen","orcid":"https://orcid.org/0000-0002-1487-5479","observed_orcids":["https://orcid.org/0000-0002-1487-5479"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Qian Chen","raw_affiliation_strings":["Department of mOncology,Lianyungang Second People Hospital,Lianyungang 222023,China"],"raw_orcid":"https://orcid.org/0000-0002-1487-5479","affiliations":[{"raw_affiliation_string":"Department of mOncology,Lianyungang Second People Hospital,Lianyungang 222023,China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35227509,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/advanced-gastric-cancer","display_name":"advanced gastric cancer","score":0.9940000176429749},{"id":"https://openalex.org/keywords/weekly-docetaxel","display_name":"weekly docetaxel","score":0.8579999804496765},{"id":"https://openalex.org/keywords/oxaliplatin","display_name":"oxaliplatin","score":0.9919999837875366},{"id":"https://openalex.org/keywords/5-fluorouracil","display_name":"5-fluorouracil","score":0.9779999852180481},{"id":"https://openalex.org/keywords/leucovorin","display_name":"leucovorin","score":0.9710000157356262},{"id":"https://openalex.org/keywords/combination-chemotherapy","display_name":"combination chemotherapy","score":0.871999979019165},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.6930000185966492},{"id":"https://openalex.org/keywords/chemotherapy-toxicity","display_name":"chemotherapy toxicity","score":0.7350000143051147},{"id":"https://openalex.org/keywords/myelosuppression","display_name":"myelosuppression","score":0.8539999723434448},{"id":"https://openalex.org/keywords/response-rate","display_name":"response rate","score":0.5099999904632568},{"id":"https://openalex.org/keywords/time-to-progression","display_name":"time to progression","score":0.8849999904632568}],"concepts":[{"id":"https://openalex.org/C2781190966","wikidata":"https://www.wikidata.org/wiki/Q420436","display_name":"Docetaxel","level":3,"score":0.9472148418426514},{"id":"https://openalex.org/C2780962732","wikidata":"https://www.wikidata.org/wiki/Q422327","display_name":"Oxaliplatin","level":4,"score":0.9436591267585754},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8760582804679871},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.6506636738777161},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5189163684844971},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.504196047782898},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.4913703501224518},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4568650424480438},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3941233158111572},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.10918384790420532},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2361744600","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-SXZL200801035.htm","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Modern Oncology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2372359500","https://openalex.org/W2371463167","https://openalex.org/W2376280796","https://openalex.org/W2367506890","https://openalex.org/W2358092446","https://openalex.org/W2388309820","https://openalex.org/W2065619958","https://openalex.org/W2363247478","https://openalex.org/W2370233528","https://openalex.org/W2348467787"],"abstract_inverted_index":{"Objective:To":[0],"observe":[1],"the":[2,87],"short":[3],"term":[4],"curative":[5],"effect,toxicity":[6],"and":[7,16,48,55,79,83,93],"quality":[8],"of":[9,14,61,76,91,106],"life":[10,107],"with":[11,25,86],"weekly":[12,89],"administration":[13,90],"docetaxel":[15,92],"oxaliplatin":[17,94],"combined":[18,95],"5-FU+LV":[19,96],"for":[20,33,37,41,46,97],"advanced":[21,26,98],"gastric":[22,27,99],"cancer.Motheds:Eighteen":[23],"cases":[24],"cancer":[28,100],"were":[29],"observed.Docetaxel":[30],"25mg/m2":[31],"iv":[32,36,40,45],"3h,d1,d8,d15.oxaliplatin":[34],"65mg/m2":[35],"3h.d1,d8.LV":[38],"100mg":[39],"2h":[42],"d1~d5.5-FU":[43],"500mg/m2":[44],"4h,d1~d5":[47],"repeated":[49],"every":[50],"28":[51],"days.To":[52],"evaluate":[53],"CR+PR":[54],"toxicity":[56],"refer":[57],"to":[58],"WHO":[59],"standard,quality":[60],"life.Results:Total":[62],"response":[63,104],"rate":[64,69],"was":[65,70,73],"55.6%.Clinical":[66],"benefit":[67],"effect":[68],"72%.Median":[71],"TTP":[72],"5.6":[74],"months.Myelosuppresion,toxicity":[75],"digestive":[77],"tract":[78],"nerve":[80],"were\u2160~\u2161":[81],"grade":[82],"tolerable.Conclusion:Patients":[84],"treated":[85],"low-dose":[88],"had":[101],"a":[102],"superior":[103],"rate.Quality":[105],"is":[108],"improved":[109],"obviously.":[110]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}