{"id":"https://openalex.org/W23606740","doi":null,"title":"[Serum pancreatic enzymes and fecal chymotrypsin before and after glyco-metabolic control in diabetic patients].","display_name":"[Serum pancreatic enzymes and fecal chymotrypsin before and after glyco-metabolic control in diabetic patients].","publication_year":1991,"publication_date":"1991-01-01","ids":{"openalex":"https://openalex.org/W23606740","mag":"23606740","pmid":"https://pubmed.ncbi.nlm.nih.gov/1719364"},"language":"it","primary_location":{"id":"pmid:1719364","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1719364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva endocrinologica","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082733849","display_name":"Giuseppe Montalto","orcid":"https://orcid.org/0000-0002-8731-8577","observed_orcids":["https://orcid.org/0000-0002-8731-8577"]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Montalto","raw_affiliation_strings":["Cattedra di Patologia Medica, Universit\u00e0 di Palermo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cattedra di Patologia Medica, Universit\u00e0 di Palermo","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088747314","display_name":"Antonio Carroccio","orcid":"https://orcid.org/0000-0001-8913-7916","observed_orcids":["https://orcid.org/0000-0001-8913-7916"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Carroccio","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089251537","display_name":"Maurizio Soresi","orcid":"https://orcid.org/0000-0001-7850-555X","observed_orcids":["https://orcid.org/0000-0001-7850-555X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Soresi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111674283","display_name":"Claudio Di Marco","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Di Marco","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001466856","display_name":"M Rocco Averna","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Rocco Averna","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5035028209","display_name":"Antonio Notarbartolo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Notarbartolo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00271344,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"1","first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.5205000042915344,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.5205000042915344,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.4169999957084656,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.027400000020861626,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9620000123977661},{"id":"https://openalex.org/keywords/pancreatic-secretion","display_name":"pancreatic secretion","score":0.597000002861023},{"id":"https://openalex.org/keywords/pancreatic-amylase","display_name":"pancreatic amylase","score":0.871999979019165},{"id":"https://openalex.org/keywords/fecal-chymotrypsin","display_name":"fecal chymotrypsin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.8320000171661377},{"id":"https://openalex.org/keywords/c-peptide","display_name":"C-peptide","score":0.875},{"id":"https://openalex.org/keywords/insulin","display_name":"insulin","score":0.5189999938011169},{"id":"https://openalex.org/keywords/pancreatic-insufficiency","display_name":"pancreatic insufficiency","score":0.6169999837875366},{"id":"https://openalex.org/keywords/secondary-diabetes-mellitus","display_name":"secondary diabetes","score":0.39899998903274536}],"concepts":[{"id":"https://openalex.org/C70818257","wikidata":"https://www.wikidata.org/wiki/Q502671","display_name":"Metabolic control analysis","level":3,"score":0.8580926656723022},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7961361408233643},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.780786395072937},{"id":"https://openalex.org/C170835558","wikidata":"https://www.wikidata.org/wiki/Q17153","display_name":"Amylase","level":3,"score":0.6912270784378052},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6733653545379639},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6538559198379517},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.5492668747901917},{"id":"https://openalex.org/C2778401398","wikidata":"https://www.wikidata.org/wiki/Q383836","display_name":"Chymotrypsin","level":4,"score":0.4696948528289795},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.4673699736595154},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4588713049888611},{"id":"https://openalex.org/C2777735490","wikidata":"https://www.wikidata.org/wiki/Q2351083","display_name":"Metabolic disorder","level":2,"score":0.4549006223678589},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.4410875141620636},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3577086329460144},{"id":"https://openalex.org/C2780340462","wikidata":"https://www.wikidata.org/wiki/Q127450","display_name":"Trypsin","level":3,"score":0.2623242139816284},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13193565607070923},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11777043342590332}],"mesh":[{"descriptor_ui":"D000681","descriptor_name":"Amylases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002096","descriptor_name":"C-Peptide","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1719364","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1719364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva endocrinologica","raw_type":"Comparative Study"},{"id":"mag:23606740","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1719364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W2109229831","https://openalex.org/W2096009885","https://openalex.org/W2151807575","https://openalex.org/W2069971988","https://openalex.org/W2080125477","https://openalex.org/W1844747712","https://openalex.org/W2066077682","https://openalex.org/W2053287196","https://openalex.org/W2075396386","https://openalex.org/W2078263362","https://openalex.org/W2015183615","https://openalex.org/W2089141914","https://openalex.org/W2082493554","https://openalex.org/W2018494933","https://openalex.org/W2068053372","https://openalex.org/W2068743553","https://openalex.org/W2145023430","https://openalex.org/W2060913542","https://openalex.org/W1988377666","https://openalex.org/W2146351491","https://openalex.org/W2030204259","https://openalex.org/W2082064411","https://openalex.org/W2105888864","https://openalex.org/W2048216460","https://openalex.org/W1998342482","https://openalex.org/W1975984062","https://openalex.org/W2000370813","https://openalex.org/W1988492326","https://openalex.org/W2089692551","https://openalex.org/W2029939672","https://openalex.org/W1972763019","https://openalex.org/W2068979602","https://openalex.org/W1964918262","https://openalex.org/W2087732778","https://openalex.org/W1991346678","https://openalex.org/W2087377825","https://openalex.org/W1966216660","https://openalex.org/W1983776254","https://openalex.org/W2001279251","https://openalex.org/W2107255006","https://openalex.org/W2032300962","https://openalex.org/W2043831700","https://openalex.org/W1550036480","https://openalex.org/W1981943245","https://openalex.org/W2127622541","https://openalex.org/W2010999288","https://openalex.org/W2054333460"],"related_works":["https://openalex.org/W2323394065","https://openalex.org/W2312518786","https://openalex.org/W1965314489","https://openalex.org/W1657368288","https://openalex.org/W2004176675","https://openalex.org/W2045033945","https://openalex.org/W1981137306","https://openalex.org/W2046939261","https://openalex.org/W2027557569","https://openalex.org/W4210921267"],"abstract_inverted_index":{"The":[0],"aim":[1],"of":[2,12,46,94,99,205,222],"the":[3,13,44,79,89,100,206,210,211,214,219],"present":[4],"study":[5],"was":[6,86,163],"to":[7,37,218],"ascertain":[8],"whether":[9],"secretory":[10,203],"capacity":[11,204],"pancreas,":[14],"evaluated":[15],"by":[16,43,165],"assaying":[17],"serum":[18],"total":[19],"amylase":[20,24],"(TA)":[21],"and":[22,27,36,51,70,97,114,125,134,154,168,176,184,208],"pancreatic":[23],"activity":[25],"(PA)":[26],"fecal":[28],"chymotrypsin":[29],"excretion":[30],"(FCT),":[31],"is":[32,41,199,213],"impaired":[33],"in":[34,55,64,195,202],"diabetic":[35,151,196],"what":[38],"extent":[39],"it":[40],"influenced":[42],"degree":[45],"glyco-metabolic":[47],"control.":[48],"TA,":[49],"PA":[50,109,143,145,177,185,212],"FCT":[52,115,135,169],"were":[53,147],"assayed":[54],"40":[56],"patients":[57,77,96,197],"affected":[58],"with":[59],"type":[60],"II":[61],"diabetes":[62],"mellitus":[63],"secondary":[65],"insufficiency,":[66],"both":[67],"at":[68],"hospitalization":[69],"after":[71,155],"metabolic":[72,90,121,156],"control":[73,80,101,122,126,157],"assessment;":[74],"43":[75],"hospitalized":[76],"constituted":[78],"group.":[81],"A":[82,159],"statistically":[83,148,160],"significant":[84,161],"difference":[85],"found":[87],"between":[88,120],"failure":[91],"phase":[92,123],"values":[93,124,146,170,178,186],"diabetics":[95],"those":[98],"group":[102,127],"for":[103,142],"TA":[104,129],"(p":[105,110,116,130,136,171,179,187],"less":[106,111,117,131,137,172,180,188],"than":[107,112,118,132,138,173,181,189],"0.0005),":[108,133],"0.025)":[113],"0.0005);":[119],"fo":[128],"0.005)":[139],"but":[140],"not":[141],"values.":[144],"significant,":[149],"within":[150],"group,":[152],"before":[153],"assessment.":[158],"result":[162],"obtained":[164],"correlating":[166],"C-peptide":[167,175],"0.01),":[174],"0.001);":[182],"glycaemia":[183],"0.05).":[190],"Our":[191],"data":[192],"suggest":[193],"that":[194,209],"there":[198],"an":[200],"impairment":[201],"pancreas":[207],"more":[215],"sensitive":[216],"enzyme":[217],"local":[220],"levels":[221],"insulin.":[223]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}