{"id":"https://openalex.org/W2357015166","doi":null,"title":"Research Progress of NKG2D and Its Ligands in Tumor Immunity","display_name":"Research Progress of NKG2D and Its Ligands in Tumor Immunity","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2357015166","mag":"2357015166"},"language":"en","primary_location":{"id":"mag:2357015166","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-SWJS200905033.htm","pdf_url":null,"source":{"id":"https://openalex.org/S192932257","display_name":"Biotechnology(Faisalabad)","issn_l":"1682-296X","issn":["1682-296X","1682-2978"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-20"],"host_organization":"https://openalex.org/P4322697005","host_organization_name":"Asian Network for Scientific Information","host_organization_lineage":["https://openalex.org/P4322697005"],"host_organization_lineage_names":["Asian Network for Scientific Information"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Biotechnology(Faisalabad)","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100688025","display_name":"Anjun Liu","orcid":"https://orcid.org/0000-0002-2824-247X","observed_orcids":["https://orcid.org/0000-0002-2824-247X"]},"institutions":[{"id":"https://openalex.org/I132369690","display_name":"Tianjin University of Science and Technology","ror":"https://ror.org/018rbtf37","country_code":"CN","type":"education","lineage":["https://openalex.org/I132369690"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Anjun Liu","raw_affiliation_strings":["College of Food Engineering & Biotechnology; Tianjin University of Science & Technology; Tianjin; 300457; China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Food Engineering & Biotechnology; Tianjin University of Science & Technology; Tianjin; 300457; China","institution_ids":["https://openalex.org/I132369690"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100688025"],"corresponding_institution_ids":["https://openalex.org/I132369690"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.31696116,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nkg2d","display_name":"NKG2D","score":0.996999979019165},{"id":"https://openalex.org/keywords/nkg2d-ligands","display_name":"NKG2D ligands","score":0.9919999837875366},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.7749999761581421},{"id":"https://openalex.org/keywords/gamma-delta-t-cells","display_name":"\u03b3\u03b4 T cells","score":0.8479999899864197},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.996999979019165},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.8870000243186951},{"id":"https://openalex.org/keywords/nk-cell-activation","display_name":"NK cell activation","score":0.7319999933242798},{"id":"https://openalex.org/keywords/ligand-regulation","display_name":"ligand regulation","score":0.5400000214576721},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.6150000095367432}],"concepts":[{"id":"https://openalex.org/C2778867473","wikidata":"https://www.wikidata.org/wiki/Q17544382","display_name":"NKG2D","level":4,"score":0.9363694787025452},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.5883362889289856},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.5428353548049927},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.46733105182647705},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.46217718720436096},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4321174621582031},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4198969602584839},{"id":"https://openalex.org/C2778102761","wikidata":"https://www.wikidata.org/wiki/Q332181","display_name":"Natural killer cell","level":4,"score":0.41949838399887085},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3706495463848114},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3368862271308899},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3360065221786499},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.22880104184150696},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10952556133270264},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2357015166","doi":null,"is_oa":false,"landing_page_url":"https://en.cnki.com.cn/Article_en/CJFDTOTAL-SWJS200905033.htm","pdf_url":null,"source":{"id":"https://openalex.org/S192932257","display_name":"Biotechnology(Faisalabad)","issn_l":"1682-296X","issn":["1682-296X","1682-2978"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-20"],"host_organization":"https://openalex.org/P4322697005","host_organization_name":"Asian Network for Scientific Information","host_organization_lineage":["https://openalex.org/P4322697005"],"host_organization_lineage_names":["Asian Network for Scientific Information"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Biotechnology(Faisalabad)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2172283401","https://openalex.org/W2375819194","https://openalex.org/W7099476714","https://openalex.org/W2087569038","https://openalex.org/W2376994365","https://openalex.org/W2385664573","https://openalex.org/W2313254135","https://openalex.org/W2046790948","https://openalex.org/W2120372745","https://openalex.org/W2994621349"],"abstract_inverted_index":{"The":[0],"activating":[1],"receptor":[2],"NKG2D(natural-killer":[3],"group":[4],"2,member":[5],"D)":[6],"and":[7,17,33,43,57,67,79,88,92],"its":[8,34,80,93],"ligands":[9,35,71,81,94],"played":[10],"an":[11],"important":[12],"role":[13],"in":[14,36,47,63,82,95],"the":[15,28,41,48,53],"NK,\u03b3\u03b4+T":[16],"CD8+T":[18],"cell-mediated":[19],"immune":[20],"response":[21],"to":[22,26],"tumors.It":[23],"was":[24],"helpful":[25],"understand":[27],"recent":[29,50],"research":[30,51],"of":[31,45,59,69,77,90],"NKG2D":[32,60,70,78,91],"tumor":[37,46,83,96],"immunity":[38],"deeply":[39],"for":[40],"prevention":[42],"treatment":[44],"clinical.The":[49],"on":[52],"molecular":[54],"structure":[55],"properties":[56],"regulation":[58,68],"were":[61,72,84,98],"introduced":[62],"this":[64],"review.Meanwhile,the":[65],"classification":[66],"also":[73],"introduced.The":[74],"effector":[75],"functions":[76],"mainly":[85],"reviewed.Present":[86],"situation":[87],"perspectives":[89],"therapy":[97],"discussed":[99],"finally.":[100]},"counts_by_year":[],"updated_date":"2026-09-21T07:43:02.447757","created_date":"2016-06-24T00:00:00"}