{"id":"https://openalex.org/W2356535310","doi":null,"title":"The Effect of Salvia plebeia on Murine Macrophage-mediated Cytotoxicity","display_name":"The Effect of Salvia plebeia on Murine Macrophage-mediated Cytotoxicity","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W2356535310","mag":"2356535310"},"language":"en","primary_location":{"id":"mag:2356535310","doi":null,"is_oa":false,"landing_page_url":"http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=E1HSBY_1996_v2n1_43","pdf_url":null,"source":{"id":"https://openalex.org/S2764419237","display_name":"Natural Product Sciences","issn_l":"1226-3907","issn":["1226-3907","2288-9027"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","kci-registered","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4366736945","host_organization_name":"Korean Society of Pharmacognosy","host_organization_lineage":["https://openalex.org/P4366736945"],"host_organization_lineage_names":["Korean Society of Pharmacognosy"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Natural Product Sciences","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057027845","display_name":"Sung-Hee Um","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sung-Hee Um","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091439257","display_name":"Kang-Ro Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kang-Ro Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057500239","display_name":"OkPyo Zee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"OkPyo Zee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5012175357","display_name":"Suhkneung Pyo","orcid":"https://orcid.org/0000-0002-8333-6268","observed_orcids":["https://orcid.org/0000-0002-8333-6268"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Suhkneung Pyo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8333-6268","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"2","issue":"1","first_page":"43","last_page":"47"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.8925999999046326,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.8925999999046326,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.06769999861717224,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.010400000028312206,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salvia-plebeia","display_name":"Salvia plebeia","score":1.0},{"id":"https://openalex.org/keywords/macrophage-mediated-cytotoxicity","display_name":"macrophage cytotoxicity","score":0.8759999871253967},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9279999732971191},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.9139999747276306},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.9369999766349792},{"id":"https://openalex.org/keywords/tumor-cell-growth-inhibition","display_name":"tumor cell growth inhibition","score":0.8140000104904175},{"id":"https://openalex.org/keywords/folk-medicine","display_name":"folk medicine","score":0.675000011920929},{"id":"https://openalex.org/keywords/tumor-immunology","display_name":"tumor immunology","score":0.4099999964237213}],"concepts":[{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.7367138862609863},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.7354840040206909},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5498471856117249},{"id":"https://openalex.org/C2776473397","wikidata":"https://www.wikidata.org/wiki/Q157151","display_name":"Salvia","level":2,"score":0.5306198596954346},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.46077319979667664},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43776530027389526},{"id":"https://openalex.org/C102124568","wikidata":"https://www.wikidata.org/wiki/Q5009626","display_name":"CCL4","level":3,"score":0.4182148873806},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.4150049090385437},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33341270685195923},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23502421379089355},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18947917222976685},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.18515396118164062},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.1601683795452118},{"id":"https://openalex.org/C2777359374","wikidata":"https://www.wikidata.org/wiki/Q225045","display_name":"Carbon tetrachloride","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2356535310","doi":null,"is_oa":false,"landing_page_url":"http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=E1HSBY_1996_v2n1_43","pdf_url":null,"source":{"id":"https://openalex.org/S2764419237","display_name":"Natural Product Sciences","issn_l":"1226-3907","issn":["1226-3907","2288-9027"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","kci-registered","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4366736945","host_organization_name":"Korean Society of Pharmacognosy","host_organization_lineage":["https://openalex.org/P4366736945"],"host_organization_lineage_names":["Korean Society of Pharmacognosy"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Natural Product Sciences","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3111688982","https://openalex.org/W4392100367","https://openalex.org/W2387578925","https://openalex.org/W2111997276","https://openalex.org/W2599358014","https://openalex.org/W1993669930","https://openalex.org/W2048141166","https://openalex.org/W1984318427","https://openalex.org/W1941152875","https://openalex.org/W2767024818"],"abstract_inverted_index":{"Macrophages":[0],"play":[1],"an":[2],"important":[3],"role":[4],"in":[5,33,86],"host":[6],"defense":[7],"against":[8],"tumors":[9],"by":[10],"killing":[11],"tumor":[12,64],"cells.":[13],"Our":[14],"work":[15],"is":[16],"directed":[17],"toward":[18],"studying":[19],"the":[20,23,44,56,61,71,79,102,105],"effect":[21],"of":[22,25,30,46,52,63,70,82,104],"extracts":[24,58],"Salvia":[26,94],"plebeia":[27,95],"on":[28],"induction":[29,103],"antitumor":[31,74,106],"activity":[32,75,81],"macrophages,":[34],"since":[35],"it":[36],"has":[37],"been":[38],"usezd":[39],"as":[40],"a":[41],"folk-medicine":[42],"for":[43,101],"treatment":[45],"hepatitis":[47],"and":[48,76],"tumors.":[49],"The":[50,68],"ability":[51],"macrophage":[53],"treated":[54],"with":[55,88],"plant":[57,72],"to":[59],"inhibit":[60],"growth":[62],"cells":[65],"was":[66],"assessed.":[67],"Extracts":[69],"induced":[73],"could":[77],"enhance":[78],"tumoricidal":[80],"macrophages":[83],"when":[84],"used":[85],"combination":[87],".":[89],"These":[90],"results":[91],"suggest":[92],"that":[93],"extract":[96],"contain":[97],"immunomodulatory":[98],"factors":[99],"responsible":[100],"activity.":[107]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}