{"id":"https://openalex.org/W2353201747","doi":"https://doi.org/10.48550/arxiv.1605.03060","title":"A Passage-of-time Model of the Cerebellar Purkinje Cell","display_name":"A Passage-of-time Model of the Cerebellar Purkinje Cell","publication_year":2016,"publication_date":"2016-05-10","ids":{"openalex":"https://openalex.org/W2353201747","doi":"https://doi.org/10.48550/arxiv.1605.03060","mag":"2353201747"},"language":"en","primary_location":{"id":"pmh:oai:arXiv.org:1605.03060","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/1605.03060","pdf_url":"https://arxiv.org/pdf/1605.03060","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["arxiv","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/1605.03060","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109334962","display_name":"Matthew R. Ricci","orcid":"https://orcid.org/0000-0001-8236-1616","observed_orcids":["https://orcid.org/0000-0001-8236-1616"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ricci, Matthew","raw_affiliation_strings":["Brown University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brown University","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kim, Junkyung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim, Junkyung","raw_affiliation_strings":["Brown University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brown University","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090246850","display_name":"Fredrik Johansson","orcid":"https://orcid.org/0000-0001-5942-0606","observed_orcids":["https://orcid.org/0000-0001-5942-0606"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Johansson, Fredrik","raw_affiliation_strings":["Lund University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lund University","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.7728999853134155,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.7728999853134155,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.10279999673366547,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":0.08009999990463257,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eyeblink-conditioning","display_name":"eyeblink conditioning","score":0.8339999914169312},{"id":"https://openalex.org/keywords/interstimulus-interval","display_name":"interstimulus interval","score":0.7490000128746033},{"id":"https://openalex.org/keywords/classical-conditioning","display_name":"classical conditioning","score":0.6949999928474426},{"id":"https://openalex.org/keywords/timing-precision","display_name":"temporal precision","score":0.41999998688697815},{"id":"https://openalex.org/keywords/tonic-inhibition","display_name":"tonic inhibition","score":0.6980000138282776},{"id":"https://openalex.org/keywords/granule-cells","display_name":"granule cells","score":0.8100000023841858},{"id":"https://openalex.org/keywords/synaptic-depression","display_name":"synaptic depression","score":0.8579999804496765},{"id":"https://openalex.org/keywords/computational-models-of-learning","display_name":"computational models of learning","score":0.4830000102519989}],"concepts":[{"id":"https://openalex.org/C2778472085","wikidata":"https://www.wikidata.org/wiki/Q1570272","display_name":"Purkinje cell","level":3,"score":0.8549033403396606},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7674273252487183},{"id":"https://openalex.org/C2778888523","wikidata":"https://www.wikidata.org/wiki/Q1777753","display_name":"Granule cell","level":4,"score":0.6012426614761353},{"id":"https://openalex.org/C2779652256","wikidata":"https://www.wikidata.org/wiki/Q130983","display_name":"Cerebellum","level":2,"score":0.46372362971305847},{"id":"https://openalex.org/C2779263132","wikidata":"https://www.wikidata.org/wiki/Q2215671","display_name":"Afferent","level":2,"score":0.4584606885910034},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43483811616897583},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24253377318382263},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.16493725776672363},{"id":"https://openalex.org/C2776464000","wikidata":"https://www.wikidata.org/wiki/Q545787","display_name":"Dentate gyrus","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:arXiv.org:1605.03060","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/1605.03060","pdf_url":"https://arxiv.org/pdf/1605.03060","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"doi:10.48550/arxiv.1605.03060","doi":"https://doi.org/10.48550/arxiv.1605.03060","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.1605.03060","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:1605.03060","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/1605.03060","pdf_url":"https://arxiv.org/pdf/1605.03060","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2353201747.pdf","grobid_xml":"https://content.openalex.org/works/W2353201747.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W122871404","https://openalex.org/W133568568","https://openalex.org/W1528959312","https://openalex.org/W1550824444","https://openalex.org/W1582681335","https://openalex.org/W1596241641","https://openalex.org/W1693262811","https://openalex.org/W1795951079","https://openalex.org/W1937980604","https://openalex.org/W1965741585","https://openalex.org/W1994919683","https://openalex.org/W1995249750","https://openalex.org/W2012198383","https://openalex.org/W2015816821","https://openalex.org/W2018761259","https://openalex.org/W2021000234","https://openalex.org/W2031402048","https://openalex.org/W2031714533","https://openalex.org/W2037593288","https://openalex.org/W2055850746","https://openalex.org/W2060694206","https://openalex.org/W2069333865","https://openalex.org/W2090286775","https://openalex.org/W2106614622","https://openalex.org/W2113364987","https://openalex.org/W2127398100","https://openalex.org/W2136879066","https://openalex.org/W2137345241","https://openalex.org/W2144367924","https://openalex.org/W2212196805"],"related_works":["https://openalex.org/W4323316856","https://openalex.org/W3005435558","https://openalex.org/W1831260922","https://openalex.org/W4226360177","https://openalex.org/W2270773227","https://openalex.org/W1494213759","https://openalex.org/W2090286775","https://openalex.org/W2618157844","https://openalex.org/W2137345241","https://openalex.org/W3212364389"],"abstract_inverted_index":{"The":[0,147],"cerebellar":[1,24],"Purkinje":[2,25,55,78,99,113,139,152],"cell":[3,26,79,83,114,140,153],"controlling":[4],"eyeblinks":[5],"can":[6,115],"learn,":[7],"remember":[8],"and":[9,95,110,141,156],"reproduce":[10,116],"the":[11,23,48,54,77,98,112,117,122,138,151,162],"interstimulus":[12],"interval":[13],"in":[14,73],"a":[15,34,63,107,131,165,169],"classical":[16],"conditioning":[17],"paradigm.":[18],"Given":[19],"temporally":[20],"separated":[21],"inputs,":[22],"learns":[27],"to":[28,59,75,121,137,144],"pause":[29],"its":[30],"tonic":[31],"inhibition":[32],"of":[33,65,125,179],"motor":[35],"pathway":[36],"with":[37],"high":[38],"temporal":[39,123],"precision":[40],"so":[41],"that":[42],"an":[43],"overt":[44],"blink":[45],"occurs":[46],"at":[47],"right":[49],"time.":[50],"Most":[51],"models":[52,84],"relegate":[53],"cell's":[56,100],"passage-of-time":[57,132],"representation":[58],"afferent":[60],"granule":[61,82,93],"cells,":[62],"subpopulation":[64],"which":[66,134,173],"is":[67,135,142,164],"supposedly":[68],"selected":[69],"for":[70,168],"synaptic":[71,180],"depression":[72],"order":[74],"make":[76],"pause.":[80],"However,":[81],"have":[85],"recently":[86],"faced":[87],"two":[88],"crucial":[89],"challenges:":[90],"1)":[91],"bypassing":[92],"cells":[94],"directly":[96],"stimulating":[97],"pre-synaptic":[101],"fibers":[102],"during":[103],"training":[104],"still":[105],"produces":[106],"well-timed":[108],"pause,":[109,119],"2)":[111],"learned":[118],"invariant":[120,143],"structure":[124],"probe":[126,145],"stimulation.":[127],"Here,":[128],"we":[129],"present":[130],"model":[133,148,163],"internal":[136],"structure.":[146],"accurately":[149],"simulates":[150],"learning":[154,171],"mechanism":[155,172],"makes":[157],"testable":[158],"electrophysiological":[159],"predictions.":[160],"Importantly,":[161],"numerical":[166],"proof-of-principle":[167],"biological":[170],"does":[174],"not":[175],"rely":[176],"on":[177],"changes":[178],"strength.":[181]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}