{"id":"https://openalex.org/W23518137","doi":null,"title":"Change of redox status and modulation by thiol replenishment in retinal photooxidative damage.","display_name":"Change of redox status and modulation by thiol replenishment in retinal photooxidative damage.","publication_year":2002,"publication_date":"2002-07-01","ids":{"openalex":"https://openalex.org/W23518137","mag":"23518137","pmid":"https://pubmed.ncbi.nlm.nih.gov/12091442"},"language":"en","primary_location":{"id":"pmid:12091442","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12091442","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042536343","display_name":"Masaki Tanito","orcid":"https://orcid.org/0000-0001-6512-7203","observed_orcids":["https://orcid.org/0000-0001-6512-7203"]},"institutions":[{"id":"https://openalex.org/I4405285000","display_name":"Shimane Medical University","ror":"https://ror.org/04kg5pk90","country_code":"JP","type":"education","lineage":["https://openalex.org/I169016828","https://openalex.org/I4405285000"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaki Tanito","raw_affiliation_strings":["Department of Ophthalmology, Shimane Medical University, 89-1 Enya, Izumo, Shimane 693-8501, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Shimane Medical University, 89-1 Enya, Izumo, Shimane 693-8501, Japan","institution_ids":["https://openalex.org/I4405285000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049861668","display_name":"Akira Nishiyama","orcid":"https://orcid.org/0000-0001-5971-820X","observed_orcids":["https://orcid.org/0000-0001-5971-820X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akira Nishiyama","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101471442","display_name":"Toru Tanaka","orcid":"https://orcid.org/0009-0004-6276-2323","observed_orcids":["https://orcid.org/0009-0004-6276-2323"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toru Tanaka","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066609674","display_name":"Hiroshi Masutani","orcid":"https://orcid.org/0000-0001-7633-2827","observed_orcids":["https://orcid.org/0000-0001-7633-2827"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroshi Masutani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Hajime Nakamura","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hajime Nakamura","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016294535","display_name":"Junji Yodoi","orcid":"https://orcid.org/0000-0001-6849-4914","observed_orcids":["https://orcid.org/0000-0001-6849-4914"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Junji Yodoi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5074918314","display_name":"Akihiro Ohira","orcid":"https://orcid.org/0000-0002-1307-5592","observed_orcids":["https://orcid.org/0000-0002-1307-5592"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akihiro Ohira","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4341,"has_fulltext":false,"cited_by_count":96,"citation_normalized_percentile":{"value":0.79005231,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"43","issue":"7","first_page":"2392","last_page":"400"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.6963000297546387,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.6963000297546387,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.15489999949932098,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.06109999865293503,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/redox-state","display_name":"redox state","score":0.8169999718666077},{"id":"https://openalex.org/keywords/n-acetylcysteine","display_name":"N-acetylcysteine","score":0.9570000171661377},{"id":"https://openalex.org/keywords/thioredoxin","display_name":"thioredoxin","score":0.9860000014305115},{"id":"https://openalex.org/keywords/glutaredoxin","display_name":"glutaredoxin","score":0.9829999804496765},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.9990000128746033},{"id":"https://openalex.org/keywords/4-hydroxynonenal","display_name":"4-hydroxynonenal","score":0.9399999976158142},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9559999704360962},{"id":"https://openalex.org/keywords/nf-kappab-nuclear-translocation","display_name":"NF-\u03baB nuclear translocation","score":0.9539999961853027},{"id":"https://openalex.org/keywords/oxidative-dna-damage","display_name":"oxidative DNA damage","score":0.828000009059906},{"id":"https://openalex.org/keywords/8-hydroxy-2-deoxyguanosine","display_name":"8-hydroxy-2'-deoxyguanosine","score":0.9959999918937683},{"id":"https://openalex.org/keywords/light-induced-retinal-injury","display_name":"light-induced retinal damage","score":0.8690000176429749},{"id":"https://openalex.org/keywords/electroretinography","display_name":"electroretinogram","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.7646567225456238},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.7578601837158203},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.6450648903846741},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6199066042900085},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5732113718986511},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.509124219417572},{"id":"https://openalex.org/C3623737","wikidata":"https://www.wikidata.org/wiki/Q421219","display_name":"Thioredoxin","level":3,"score":0.49405911564826965},{"id":"https://openalex.org/C2777847592","wikidata":"https://www.wikidata.org/wiki/Q375613","display_name":"Acetylcysteine","level":3,"score":0.4486600458621979},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.44853925704956055},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.4460066556930542},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.42813628911972046},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.404537558555603},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3762284815311432},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26013463735580444},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.07870960235595703},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.060733288526535034},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000080242","descriptor_name":"8-Hydroxy-2'-Deoxyguanosine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000111","descriptor_name":"Acetylcysteine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003432","descriptor_name":"Cross-Linking Reagents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D003849","descriptor_name":"Deoxyguanosine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D003849","descriptor_name":"Deoxyguanosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004596","descriptor_name":"Electroretinography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005978","descriptor_name":"Glutathione","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011833","descriptor_name":"Radiation Injuries, Experimental","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011833","descriptor_name":"Radiation Injuries, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011833","descriptor_name":"Radiation Injuries, Experimental","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D012162","descriptor_name":"Retinal Degeneration","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012162","descriptor_name":"Retinal Degeneration","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012162","descriptor_name":"Retinal Degeneration","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D013879","descriptor_name":"Thioredoxins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054477","descriptor_name":"Glutaredoxins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:12091442","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12091442","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},{"id":"mag:23518137","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12091442","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W9706752","https://openalex.org/W74738218","https://openalex.org/W133332135","https://openalex.org/W153199482","https://openalex.org/W164426026","https://openalex.org/W169303963","https://openalex.org/W181745092","https://openalex.org/W1560493291","https://openalex.org/W1707178069","https://openalex.org/W1906993142","https://openalex.org/W1928195896","https://openalex.org/W1957447204","https://openalex.org/W1963653572","https://openalex.org/W1966308856","https://openalex.org/W1967005305","https://openalex.org/W1968290611","https://openalex.org/W1969268163","https://openalex.org/W1973874388","https://openalex.org/W1991387227","https://openalex.org/W1997354645","https://openalex.org/W1998499720","https://openalex.org/W2005616215","https://openalex.org/W2007064404","https://openalex.org/W2008966397","https://openalex.org/W2010521754","https://openalex.org/W2012744796","https://openalex.org/W2016883855","https://openalex.org/W2026512497","https://openalex.org/W2026609982","https://openalex.org/W2027716003","https://openalex.org/W2028101737","https://openalex.org/W2032661669","https://openalex.org/W2038916738","https://openalex.org/W2048666160","https://openalex.org/W2049328344","https://openalex.org/W2052912964","https://openalex.org/W2057522312","https://openalex.org/W2060123467","https://openalex.org/W2061234219","https://openalex.org/W2065634577","https://openalex.org/W2065733477","https://openalex.org/W2069326406","https://openalex.org/W2075303826","https://openalex.org/W2077324620","https://openalex.org/W2085090936","https://openalex.org/W2088696081","https://openalex.org/W2092895233","https://openalex.org/W2094321502","https://openalex.org/W2094646101","https://openalex.org/W2095301528","https://openalex.org/W2128040527","https://openalex.org/W2141802124","https://openalex.org/W2147851592","https://openalex.org/W2152486698","https://openalex.org/W2153403950","https://openalex.org/W2154975058","https://openalex.org/W2155349225","https://openalex.org/W2157186872","https://openalex.org/W2161222674","https://openalex.org/W2163073894","https://openalex.org/W2166056798","https://openalex.org/W2206882388","https://openalex.org/W2240454133","https://openalex.org/W2406899559","https://openalex.org/W2413473241","https://openalex.org/W2419010349","https://openalex.org/W4237446574","https://openalex.org/W4251225651"],"related_works":["https://openalex.org/W1523591713","https://openalex.org/W2060458883","https://openalex.org/W7098030364","https://openalex.org/W2127342236","https://openalex.org/W2064466363","https://openalex.org/W99032343","https://openalex.org/W2741819157","https://openalex.org/W4402328475","https://openalex.org/W2906609084","https://openalex.org/W3114505643"],"abstract_inverted_index":{"PURPOSE:":[0],"Cellular":[1],"or":[2,50,104],"tissue":[3,19,226,231],"reduction-oxidation":[4],"(redox)":[5],"is":[6,22,208,214],"crucial":[7],"in":[8,94,130,155,162,176,197,201],"various":[9],"diseases.":[10],"The":[11,179],"present":[12],"study":[13],"was":[14,97,128,170,191],"conducted":[15],"to":[16,56,243],"analyze":[17],"how":[18],"redox":[20,206,232],"status":[21,207],"affected":[23],"by":[24,99,112,210,217,234],"photooxidative":[25,36,246],"stress":[26],"and":[27,54,71,86,101,114,132,139,145,181,187,213,224],"whether":[28],"the":[29,188,218,230],"exogenous":[30,235],"thiol":[31,236],"antioxidant":[32],"N-acetylcysteine":[33],"(NAC)":[34],"affects":[35],"stress-induced":[37,125],"retinal":[38,95,109,245],"damage.":[39,247],"METHODS:":[40],"Mice":[41],"were":[42,150,160,184],"intraperitoneally":[43],"injected":[44],"with":[45,166],"either":[46],"NAC":[47,221],"(250":[48],"mg/kg)":[49],"phosphate-buffered":[51],"saline":[52],"(PBS)":[53],"exposed":[55],"white":[57],"fluorescent":[58],"light":[59,153,174,195,212],"(8000":[60],"lux)":[61],"for":[62,117],"2":[63],"hours.":[64],"Levels":[65],"of":[66,76,83,123,137,143,148,220,229],"thioredoxin":[67],"(TRX),":[68],"glutaredoxin":[69],"(GRX),":[70],"glutathione":[72],"(GSH),":[73],"endogenous":[74],"regulators":[75],"redox;":[77],"4-hydroxy-2-nonenal":[78],"(HNE)-modified":[79],"protein,":[80,141],"a":[81,90,121,240],"marker":[82,122],"lipid":[84],"peroxidation;":[85],"nuclear":[87,146],"factor":[88,93],"(NF)-kappaB,":[89],"redox-sensitive":[91],"transcription":[92],"samples,":[96],"measured":[98],"immunohistochemistry":[100,116],"Western":[102],"blot":[103],"enzymatic":[105],"recycling":[106],"assay.":[107],"Light-induced":[108],"damage":[110],"estimated":[111],"electroretinography":[113],"quantitative":[115],"8-hydroxy-2-deoxyguanosine":[118],"(8OHdG":[119],"index),":[120],"oxidative":[124],"DNA":[126],"damage,":[127],"compared":[129,165],"NAC-":[131],"PBS-treated":[133,156,167,202],"mice.":[134,157,168,178,203],"RESULTS:":[135],"Upregulation":[136],"TRX":[138,223],"HNE-modified":[140],"decrease":[142],"GSH,":[144],"translocation":[147],"NF-kappaB":[149],"noted":[151],"after":[152,173,194],"exposure":[154,175,196],"These":[158],"changes":[159],"suppressed":[161],"NAC-treated":[163,198],"mice":[164,199],"GRX":[169],"not":[171],"upregulated":[172],"any":[177],"a-":[180],"b-wave":[182],"amplitudes":[183],"significantly":[185,192],"higher,":[186],"8OHdG":[189],"index":[190],"lower":[193],"than":[200],"CONCLUSIONS:":[204],"Retinal":[205],"altered":[209],"intense":[211],"normalized":[215],"partially":[216],"effect":[219],"on":[222],"GSH":[225],"levels.":[227],"Manipulation":[228],"state":[233],"replenishment":[237],"may":[238],"be":[239],"useful":[241],"strategy":[242],"prevent":[244]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}