{"id":"https://openalex.org/W2350418080","doi":null,"title":"Change and significance of ABCG2 expression in esophageal cancer tissue","display_name":"Change and significance of ABCG2 expression in esophageal cancer tissue","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2350418080","mag":"2350418080"},"language":"en","primary_location":{"id":"mag:2350418080","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-SDYY201118010.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764537232","display_name":"Shandong yiyao","issn_l":"1002-266X","issn":["1002-266X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4361727546","host_organization_name":"Shandong Provincial Department of Health","host_organization_lineage":["https://openalex.org/P4361727546"],"host_organization_lineage_names":["Shandong Provincial Department of Health"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Shandong yiyao","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061985538","display_name":"MA Chun-sheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"MA Chun-sheng","raw_affiliation_strings":["1 Changhai Hospital,Second Military Medical University,Shanghai 200433,P"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Changhai Hospital,Second Military Medical University,Shanghai 200433,P","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210115928"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5061985538"],"corresponding_institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210115928"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28076132,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.08349999785423279,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abcg2","display_name":"ABCG2","score":1.0},{"id":"https://openalex.org/keywords/esophageal-cancer","display_name":"esophageal cancer","score":0.9559999704360962},{"id":"https://openalex.org/keywords/esophageal-squamous-cell-carcinoma","display_name":"esophageal squamous cell carcinoma","score":0.9869999885559082},{"id":"https://openalex.org/keywords/protein-expression","display_name":"protein expression","score":0.6179999709129333},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8040000200271606},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.6539999842643738},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C512196","wikidata":"https://www.wikidata.org/wiki/Q4650095","display_name":"Abcg2","level":5,"score":0.9062106013298035},{"id":"https://openalex.org/C2779742542","wikidata":"https://www.wikidata.org/wiki/Q372701","display_name":"Esophageal cancer","level":3,"score":0.8831703662872314},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.7132135629653931},{"id":"https://openalex.org/C3019814559","wikidata":"https://www.wikidata.org/wiki/Q681817","display_name":"Squamous cell cancer","level":3,"score":0.645461916923523},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6255064606666565},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4945344626903534},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.48460114002227783},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.43297091126441956},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.42688262462615967},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4214325547218323},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.37990328669548035},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3115810751914978},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30711913108825684},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.05547976493835449},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C44312359","wikidata":"https://www.wikidata.org/wiki/Q286958","display_name":"ATP-binding cassette transporter","level":4,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2350418080","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-SDYY201118010.htm","pdf_url":null,"source":{"id":"https://openalex.org/S2764537232","display_name":"Shandong yiyao","issn_l":"1002-266X","issn":["1002-266X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4361727546","host_organization_name":"Shandong Provincial Department of Health","host_organization_lineage":["https://openalex.org/P4361727546"],"host_organization_lineage_names":["Shandong Provincial Department of Health"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Shandong yiyao","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1971561964","https://openalex.org/W2356358066","https://openalex.org/W2139164858","https://openalex.org/W2381512357","https://openalex.org/W2012320279","https://openalex.org/W2120211691","https://openalex.org/W2413948426","https://openalex.org/W2067662506","https://openalex.org/W1966588658","https://openalex.org/W2267413798"],"abstract_inverted_index":{"Objective":[0],"To":[1],"study":[2],"the":[3,14,26],"expression":[4,50,63,77],"of":[5,39,49,51,64,78],"ABCG2":[6,27,40,52,65,79],"in":[7,28,41,53,66,82,94],"esophageal":[8,23,54,67,83,95],"cancer":[9,29,42,55,68,84],"tissue":[10,43],"and":[11,30,35],"to":[12,58,73],"investigation":[13],"significance.Method":[15],"Specimens":[16],"was":[17,44,56,69],"gained":[18],"from":[19],"80":[20],"patients":[21],"with":[22],"cancer,which":[24],"detect":[25],"normal":[31,47],"specimens":[32],"by":[33],"immunohistochemistry":[34],"Western":[36],"blot.Results":[37],"Expression":[38],"increased":[45,62],"than":[46],"tissue(P0.05).Quantity":[48],"contribute":[57,72],"3":[59],"a":[60,90],"mortality(P0.01),and":[61],"tumor":[70],"specific":[71],"early":[74],"recurrences(P0.05).Conclusions":[75],"The":[76],"is":[80],"up-regulated":[81],"tissue.ABCG2":[85],"may":[86],"be":[87],"considered":[88],"as":[89],"supplementary":[91],"predictor":[92],"prognostic":[93],"squamous":[96],"cell":[97],"cancer.":[98]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}