{"id":"https://openalex.org/W2346791027","doi":"https://doi.org/10.51481/amc.v51i1.32","title":"Creatina s\u00e9rica elevada en el paciente hipotiroideo: miopat\u00eda o verdadera nefropat\u00eda? Propuesta de clasificaci\u00f3n.","display_name":"Creatina s\u00e9rica elevada en el paciente hipotiroideo: miopat\u00eda o verdadera nefropat\u00eda? Propuesta de clasificaci\u00f3n.","publication_year":2008,"publication_date":"2008-12-16","ids":{"openalex":"https://openalex.org/W2346791027","doi":"https://doi.org/10.51481/amc.v51i1.32","mag":"2346791027"},"language":"es","primary_location":{"id":"doi:10.51481/amc.v51i1.32","doi":"https://doi.org/10.51481/amc.v51i1.32","is_oa":true,"landing_page_url":"https://doi.org/10.51481/amc.v51i1.32","pdf_url":"http://actamedica.medicos.cr/index.php/Acta_Medica/article/download/32/26","source":{"id":"https://openalex.org/S4210198485","display_name":"Acta M\u00e9dica Costarricense","issn_l":"0001-6012","issn":["0001-6012","2215-5856"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","latindex","norway-1","scielo"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta M\u00e9dica Costarricense","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://actamedica.medicos.cr/index.php/Acta_Medica/article/download/32/26","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113045423","display_name":"Carmen Lidia Guerrero-Lobo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31944674","display_name":"Universidad de Costa Rica","ror":"https://ror.org/02yzgww51","country_code":"CR","type":"education","lineage":["https://openalex.org/I31944674"]}],"countries":["CR"],"is_corresponding":true,"raw_author_name":"Carmen Lidia Guerrero Lobo","raw_affiliation_strings":["Universidad de Costa Rica"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidad de Costa Rica","institution_ids":["https://openalex.org/I31944674"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113045423"],"corresponding_institution_ids":["https://openalex.org/I31944674"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"51","issue":"1","first_page":"44","last_page":"48"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12117","display_name":"Muscle and Compartmental Disorders","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothyroidism","display_name":"hypothyroidism","score":0.9089999794960022},{"id":"https://openalex.org/keywords/serum-creatinine","display_name":"serum creatinine","score":0.7940000295639038},{"id":"https://openalex.org/keywords/myopathy","display_name":"myopathy","score":0.628000020980835},{"id":"https://openalex.org/keywords/kidney-disease","display_name":"kidney disease","score":0.7509999871253967},{"id":"https://openalex.org/keywords/rhabdomyolysis","display_name":"rhabdomyolysis","score":0.8220000267028809},{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.8820000290870667},{"id":"https://openalex.org/keywords/thyroid-stimulating-hormone","display_name":"thyroid-stimulating hormone","score":0.7649999856948853},{"id":"https://openalex.org/keywords/levothyroxine","display_name":"levothyroxine","score":0.6650000214576721},{"id":"https://openalex.org/keywords/amiodarone","display_name":"amiodarone","score":0.7990000247955322},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.843999981880188},{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.9070000052452087},{"id":"https://openalex.org/keywords/gemfibrozil","display_name":"gemfibrozil","score":0.9419999718666077},{"id":"https://openalex.org/keywords/proteinuria","display_name":"proteinuria","score":0.7099999785423279},{"id":"https://openalex.org/keywords/nephrotic-syndrome","display_name":"nephrotic syndrome","score":0.9290000200271606},{"id":"https://openalex.org/keywords/hashimoto-s-thyroiditis","display_name":"Hashimoto's thyroiditis","score":0.8539999723434448},{"id":"https://openalex.org/keywords/glomerular-disease","display_name":"glomerular disease","score":0.8040000200271606}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7482725381851196},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.5522235035896301},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.14840176701545715}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.51481/amc.v51i1.32","doi":"https://doi.org/10.51481/amc.v51i1.32","is_oa":true,"landing_page_url":"https://doi.org/10.51481/amc.v51i1.32","pdf_url":"http://actamedica.medicos.cr/index.php/Acta_Medica/article/download/32/26","source":{"id":"https://openalex.org/S4210198485","display_name":"Acta M\u00e9dica Costarricense","issn_l":"0001-6012","issn":["0001-6012","2215-5856"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","latindex","norway-1","scielo"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta M\u00e9dica Costarricense","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:7c9a63dfb4e842f0b4551536585d588b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7c9a63dfb4e842f0b4551536585d588b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta M\u00e9dica Costarricense, Vol 51, Iss 1, Pp 44-48 (2009)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:8ec0739a73e34fc48f2aa68b56c77816","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/8ec0739a73e34fc48f2aa68b56c77816","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta M\u00e9dica Costarricense, Vol 51, Iss 1, Pp 44-48 (2009)","raw_type":"article"},{"id":"pmh:oai:redalyc.org:43411949009","doi":null,"is_oa":false,"landing_page_url":"https://www.redalyc.org/articulo.oa?id=43411949009","pdf_url":null,"source":{"id":"https://openalex.org/S4377196100","display_name":"Redalyc (Universidad Aut\u00f3noma del Estado de M\u00e9xico)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I179647637","host_organization_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","host_organization_lineage":["https://openalex.org/I179647637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta M\u00e9dica Costarricense (Costa Rica) Num.1 Vol.51","raw_type":"art\u00edculo cient\u00edfico"},{"id":"mag:2785961686","doi":null,"is_oa":true,"landing_page_url":"https://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S0001-60022009000100009","pdf_url":null,"source":{"id":"https://openalex.org/S4210198485","display_name":"Acta M\u00e9dica Costarricense","issn_l":"0001-6012","issn":["0001-6012","2215-5856"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","latindex","norway-1","scielo"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Acta M\u00e9dica Costarricense","raw_type":null}],"best_oa_location":{"id":"doi:10.51481/amc.v51i1.32","doi":"https://doi.org/10.51481/amc.v51i1.32","is_oa":true,"landing_page_url":"https://doi.org/10.51481/amc.v51i1.32","pdf_url":"http://actamedica.medicos.cr/index.php/Acta_Medica/article/download/32/26","source":{"id":"https://openalex.org/S4210198485","display_name":"Acta M\u00e9dica Costarricense","issn_l":"0001-6012","issn":["0001-6012","2215-5856"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","latindex","norway-1","scielo"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta M\u00e9dica Costarricense","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2346791027.pdf","grobid_xml":"https://content.openalex.org/works/W2346791027.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W18836138","https://openalex.org/W88652696","https://openalex.org/W341072046","https://openalex.org/W1513738324","https://openalex.org/W1543981976","https://openalex.org/W1964787889","https://openalex.org/W1968002151","https://openalex.org/W1973346549","https://openalex.org/W1976236682","https://openalex.org/W1976647515","https://openalex.org/W1984192886","https://openalex.org/W1995463150","https://openalex.org/W1999413669","https://openalex.org/W2028137157","https://openalex.org/W2033776988","https://openalex.org/W2041371200","https://openalex.org/W2048305349","https://openalex.org/W2052124893","https://openalex.org/W2056821140","https://openalex.org/W2068644867","https://openalex.org/W2077166692","https://openalex.org/W2086702076","https://openalex.org/W2090071564","https://openalex.org/W2107001904","https://openalex.org/W2116492782","https://openalex.org/W2116755529","https://openalex.org/W2119369715","https://openalex.org/W2135020311","https://openalex.org/W2164804020","https://openalex.org/W2180745593","https://openalex.org/W2321935435"],"related_works":["https://openalex.org/W4403619339","https://openalex.org/W4388618669","https://openalex.org/W2785961686","https://openalex.org/W2164804020","https://openalex.org/W2028137157","https://openalex.org/W7132164396","https://openalex.org/W1999413669","https://openalex.org/W2132695157","https://openalex.org/W4242249942","https://openalex.org/W2150406719"],"abstract_inverted_index":{"Justificaci\u00f3n:":[0],"En":[1,186],"el":[2,131,141,263],"paciente":[3,81,277],"hipotiroideo":[4,278],"la":[5,34,39,52,109,122,158,169,182,205,281],"creatinina":[6,44,53],"s\u00e9rica":[7,54,84,219,251],"puede":[8,66,283,289],"aumentar":[9],"no":[10,77,119],"solo":[11],"por":[12,17,208],"fallo":[13],"renal,":[14],"sino":[15],"tambi\u00e9n":[16],"miopat\u00eda":[18],"en":[19,75,145,160,211,215,221,231],"presencia":[20],"de":[21,30,33,51,143,151,162,168,176,184,190,204,271],"funci\u00f3n":[22,59,88,110,123,273],"renal":[23,60,73,89,153,244],"normal.":[24],"Se":[25,247],"reportan":[26],"2":[27],"pacientes":[28,187,216,254],"representativos":[29],"sendos":[31],"tipos":[32],"clasificaci\u00f3n":[35],"aqu\u00ed":[36],"propuesta":[37],"sobre":[38],"asociaci\u00f3n":[40],"disfunci\u00f3n":[41],"tiroidea":[42,124],"/":[43],"s\u00e9rica.":[45],"El":[46,79,112,148],"primer":[47],"enfermo":[48],"presenta":[49],"aumento":[50],"secundario":[55],"a":[56,197,252,260],"miopat\u00edahipotiroidea":[57],"con":[58,68,82,115,140,155,166,181,188,217,223,238,265,293],"normal":[61],"(tipo":[62,94],"1),":[63],"esta":[64],"se":[65,107,120,126,129],"complicar":[67],"rabdomiolisis":[69,237],"y":[70,101,105,117,125,230,259],"causar":[71],"insuficiencia":[72,243],"aguda":[74],"hipotiroideos":[76,255],"diagnosticada.":[78],"otro":[80],"creatina":[83,218,239,250],"alta":[85],"mejor\u00f3":[86],"su":[87,92,272,298],"al":[90,102,291],"tratarse":[91],"hipotiroidismo":[93,113,156],"2).":[95],"Ocasionalmente,":[96],"este":[97],"ha":[98,138],"permanecido":[99],"oculto":[100],"ser":[103],"diagnosticado":[104],"tratado,":[106],"mejora":[108],"renal.":[111,274],"cursa":[114],"hipercolesterolemia":[116],"si":[118,297],"valora":[121],"administran":[127],"estatinas,":[128],"empeora":[130],"da\u00f1o":[132,152],"muscular":[133],"del":[134],"paciente.":[135],"Lo":[136],"mismo":[137],"sucedido":[139],"uso":[142],"gemfibrozil":[144],"condiciones":[146],"similares.":[147],"tercer":[149],"tipo":[150],"relacionado":[154],"es":[157,300],"proteinuria":[159],"rango":[161],"s\u00edndrome":[163,286],"nefr\u00f3tico,":[164],"vinculada":[165],"suspensi\u00f3n":[167],"levotiroxina.":[170,185],"Las":[171],"biopsias":[172],"muestran":[173],"lesiones":[174],"histol\u00f3gicas":[175],"diversas":[177],"glomerulopat\u00edas,":[178],"que":[179,195,233,256,279,288],"mejoran":[180],"administraci\u00f3n":[183],"tiroiditis":[189],"Hashimoto":[191],"aparecen":[192],"otras":[193],"glomerulopat\u00edas":[194],"responden":[196],"los":[198,232,253],"glucocorticoides.Conclusi\u00f3n:":[199],"1)":[200],"La":[201],"hormona":[202],"estimulante":[203],"tiroides":[206],"(TSH":[207],"sus":[209],"siglas":[210],"ingl\u00e9s)":[212],"debe":[213,248],"cuantificarse":[214],"aumentada,":[220],"aquellos":[222],"colesterol":[224],"elevado":[225],"sin":[226],"una":[227],"causa":[228],"evidente":[229],"tienen":[234],"polimiositis":[235],"o":[236,295,302],"fosfocinasa":[240],"elevada":[241],"e":[242],"aguda.":[245],"2)":[246],"solicitar":[249],"usan":[257],"amiodarona":[258],"quienes":[261],"suspenden":[262],"tratamiento":[264,292],"levotiroxina,":[266,296],"pues":[267],"pueden":[268],"presentar":[269],"disminuci\u00f3n":[270],"3)":[275],"Un":[276],"descontinu\u00f3":[280],"levotiroxina":[282],"desarrollar":[284],"un":[285],"nefr\u00f3tico":[287],"responder":[290],"glucocorticoides":[294],"origen":[299],"inmunol\u00f3gico":[301],"no.":[303]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}