{"id":"https://openalex.org/W2344767208","doi":null,"title":"Serum homocysteine level and gall stone disease: a case control study","display_name":"Serum homocysteine level and gall stone disease: a case control study","publication_year":2010,"publication_date":"2010-11-01","ids":{"openalex":"https://openalex.org/W2344767208","mag":"2344767208"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:cb416ed88dfc4478bfff3659f4e365ed","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cb416ed88dfc4478bfff3659f4e365ed","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tehran University Medical Journal, Vol 68, Iss 8, Pp 481-486 (2010)","raw_type":"article"},"volume":null,"type":"article","indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/cb416ed88dfc4478bfff3659f4e365ed","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064886954","display_name":"Reza Afghani","orcid":"https://orcid.org/0000-0001-6768-2446","observed_orcids":["https://orcid.org/0000-0001-6768-2446"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Afghani R","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065228810","display_name":"Ali Aminian","orcid":"https://orcid.org/0000-0001-5756-9917","observed_orcids":["https://orcid.org/0000-0001-5756-9917","https://orcid.org/0000-0002-3313-6364"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aminian A","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073402070","display_name":"Rasoul Mirsharifi","orcid":"https://orcid.org/0000-0002-1676-4318","observed_orcids":["https://orcid.org/0000-0002-1676-4318"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mirsharifi SR","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009786416","display_name":"Ali Jafarian","orcid":"https://orcid.org/0000-0001-5375-8980","observed_orcids":["https://orcid.org/0000-0001-5375-8980"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jafarian A","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021826022","display_name":"Hamid Ghaderi","orcid":"https://orcid.org/0000-0001-5273-7053","observed_orcids":["https://orcid.org/0000-0001-5273-7053"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ghaderi H","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038608159","display_name":"Morteza Noaparast","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Noaparast M","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5007798439","display_name":"Sahar Dashti","orcid":"https://orcid.org/0009-0005-8403-5570","observed_orcids":["https://orcid.org/0009-0005-8403-5570"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dashti SH","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.30186548,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.8393999934196472,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.8393999934196472,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.07370000332593918,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serum-homocysteine","display_name":"serum homocysteine","score":0.9380000233650208},{"id":"https://openalex.org/keywords/hyperhomocysteinemia","display_name":"hyperhomocysteinemia","score":0.953000009059906},{"id":"https://openalex.org/keywords/gallstone-disease","display_name":"gallstone disease","score":0.8899999856948853},{"id":"https://openalex.org/keywords/gallstones","display_name":"gallstones","score":0.8730000257492065},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.6019999980926514},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.7129999995231628},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6269999742507935},{"id":"https://openalex.org/keywords/gallbladder-ultrasound","display_name":"gallbladder ultrasound","score":0.46299999952316284},{"id":"https://openalex.org/keywords/case-control-study","display_name":"case-control study","score":0.41999998688697815}],"concepts":[{"id":"https://openalex.org/C2777451525","wikidata":"https://www.wikidata.org/wiki/Q224107","display_name":"Gall","level":2,"score":0.6060296893119812},{"id":"https://openalex.org/C2777090595","wikidata":"https://www.wikidata.org/wiki/Q192466","display_name":"Homocysteine","level":2,"score":0.5800015330314636},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.569379448890686},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4950529634952545},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.413187175989151},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3238005042076111},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21371382474899292},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0840333104133606}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:doaj.org/article:cb416ed88dfc4478bfff3659f4e365ed","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cb416ed88dfc4478bfff3659f4e365ed","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tehran University Medical Journal, Vol 68, Iss 8, Pp 481-486 (2010)","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:cb416ed88dfc4478bfff3659f4e365ed","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cb416ed88dfc4478bfff3659f4e365ed","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tehran University Medical Journal, Vol 68, Iss 8, Pp 481-486 (2010)","raw_type":"article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2150400395","https://openalex.org/W4366263416","https://openalex.org/W2074189361","https://openalex.org/W4416948425","https://openalex.org/W2093882767","https://openalex.org/W2618816762","https://openalex.org/W6893075812","https://openalex.org/W4410390869","https://openalex.org/W2084649463","https://openalex.org/W2379777834"],"abstract_inverted_index":{"\"n":[0],"Normal":[1],"0":[2],"false":[3,4,5],"EN-US":[6],"X-NONE":[7],"AR-SA":[8],"MicrosoftInternetExplorer4":[9],"/*":[10],"Style":[11],"Definitions":[12],"*/":[13],"table.MsoNormalTable":[14],"{mso-style-name:\"Table":[15],"Normal\";":[16],"mso-tstyle-rowband-size:0;":[17],"mso-tstyle-colband-size:0;":[18],"mso-style-noshow:yes;":[19],"mso-style-priority:99;":[20],"mso-style-qformat:yes;":[21],"mso-style-parent:\"\";":[22],"mso-padding-alt:0in":[23],"5.4pt":[24],"0in":[25],"5.4pt;":[26],"mso-para-margin:0in;":[27],"mso-para-margin-bottom:.0001pt;":[28],"mso-pagination:widow-orphan;":[29],"font-size:11.0pt;":[30],"font-family:\"Calibri\",\"sans-serif\";":[31],"mso-ascii-font-family:Calibri;":[32],"mso-ascii-theme-font:minor-latin;":[33],"mso-fareast-font-family:\"Times":[34],"New":[35],"Roman\";":[36],"mso-fareast-theme-font:minor-fareast;":[37],"mso-hansi-font-family:Calibri;":[38],"mso-hansi-theme-font:minor-latin;":[39],"mso-bidi-font-family:Arial;":[40],"mso-bidi-theme-font:minor-bidi;}":[41],"Background:":[42],"Gall":[43,61],"stone":[44,62,93,106,180,250,274],"is":[45,71,256],"an":[46],"important":[47],"health":[48],"problem":[49],"in":[50,132,167,171,184,203,217,236,245,258],"the":[51,76,86,246],"world":[52],"for":[53,79,248],"which":[54],"different":[55],"risk":[56,68,77,247,270],"factors":[57,78],"have":[58,66,187],"been":[59],"characterized.":[60],"and":[63,102,155,222,230],"cardiovascular":[64,80],"disease":[65],"common":[67],"factors.":[69],"Homocysteine":[70,135,162,264],"accepted":[72],"as":[73,146,268],"one":[74,233],"of":[75,88,137,159,178,199,211,272],"disease.":[81],"We":[82],"aimed":[83],"to":[84,114,173],"study":[85],"effect":[87],"homocysteine":[89,128,188,200,212,254],"level":[90,129,136,163,189,198,210,238,255],"on":[91],"gall":[92,99,179,249,261,273],"formation.":[94,275],"\"n\"nMethods:":[95],"54":[96,103],"patients":[97,104,168,218,223,259],"with":[98,122,169,219,224,241,260],"stone-related":[100,262],"diseases":[101],"without":[105],"(control":[107],"group)":[108],"were":[109],"studied":[110],"from":[111],"January":[112],"2007":[113],"December":[115],"2008.":[116],"Control":[117],"group":[118,175],"consisted":[119],"healthy":[120],"subjects":[121],"ultrasound":[123],"proven":[124],"normal":[125],"gallbladder.":[126],"Serum":[127],"was":[130,144,164,201,239],"checked":[131],"both":[133],"groups.":[134],"equal":[138,190],"or":[139,191],"more":[140],"than":[141,193,205],"15":[142],"mmol/l":[143],"considered":[145,267],"abnormally":[147],"high.":[148],"\"n\"nResults:":[149],"Cases":[150],"included":[151],"43":[152],"women":[153,206],"(79.6%)":[154],"had":[156],"mean":[157,197,209],"age":[158],"50.76\u00b115.23":[160],"years.":[161],"significantly":[165,216],"higher":[166,202],"gallstone":[170,221],"comparison":[172],"control":[174],"(p=0.014).":[176],"Risk":[177],"increased":[181,257],"3.4":[182],"times":[183,243],"persons":[185],"who":[186],"greater":[192],"15mmol/l":[194],"(p=0.019).":[195],"The":[196,208,253],"men":[204],"(p=0.03).":[207],"did":[213],"not":[214],"differ":[215],"simple":[220],"gallstone-related":[225],"inflammation":[226],"disorders":[227],"(cholecystitis,":[228],"cholangitis,":[229],"pancreatitis).":[231],"Additionally,":[232],"unit":[234],"increase":[235,244],"BMI":[237],"associated":[240],"1.12":[242],"formation":[251],"(p=0.035).\"n\"nConclusion:":[252],"diseases.":[263],"may":[265],"be":[266],"a":[269],"factor":[271]},"counts_by_year":[],"updated_date":"2026-10-02T10:15:12.560889","created_date":"2016-06-24T00:00:00"}