{"id":"https://openalex.org/W2343348434","doi":"https://doi.org/10.1016/j.jaci.2015.12.1038","title":"Airway but Not Blood Type 2 Innate Lymphoid Cells (ILC2s) from Asthmatic Patients Are Steroid-Resistant, Which Is Induced By IL7R-Alpha Ligands","display_name":"Airway but Not Blood Type 2 Innate Lymphoid Cells (ILC2s) from Asthmatic Patients Are Steroid-Resistant, Which Is Induced By IL7R-Alpha Ligands","publication_year":2016,"publication_date":"2016-02-01","ids":{"openalex":"https://openalex.org/W2343348434","doi":"https://doi.org/10.1016/j.jaci.2015.12.1038","mag":"2343348434"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaci.2015.12.1038","doi":"https://doi.org/10.1016/j.jaci.2015.12.1038","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaci.2015.12.1038","pdf_url":"http://www.jacionline.org/article/S0091674915027803/pdf","source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jacionline.org/article/S0091674915027803/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112752881","display_name":"Rafeul Alam","orcid":"https://orcid.org/0000-0001-8562-4207","observed_orcids":["https://orcid.org/0000-0001-8562-4207"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rafeul Alam","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085098525","display_name":"Sucai Liu","orcid":"https://orcid.org/0000-0002-9274-9216","observed_orcids":["https://orcid.org/0000-0002-9274-9216"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sucai Liu","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020199317","display_name":"Mukesh Verma","orcid":"https://orcid.org/0000-0002-1817-0863","observed_orcids":["https://orcid.org/0000-0002-1817-0863"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Verma Mukesh","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100367600","display_name":"Weimin Liu","orcid":"https://orcid.org/0000-0001-7508-0947","observed_orcids":["https://orcid.org/0000-0001-7508-0947"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Weimin Liu","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101404198","display_name":"Magdalena M. Gorska","orcid":"https://orcid.org/0000-0001-7364-8703","observed_orcids":["https://orcid.org/0000-0001-7364-8703"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Magdalena M. Gorska","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109906579","display_name":"James T. Good","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Good","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082890483","display_name":"Donald R. Rollins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald Rollins","raw_affiliation_strings":["National Jewish Health, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Jewish Health, Denver, CO","institution_ids":["https://openalex.org/I3019586173"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I3019586173"],"apc_list":{"value":4900,"currency":"USD","value_usd":4900},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.02694802,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"137","issue":"2","first_page":"AB275","last_page":"AB275"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12528","display_name":"IL-33, ST2, and ILC Pathways","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12528","display_name":"IL-33, ST2, and ILC Pathways","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/group-2-innate-lymphoid-cells","display_name":"ILC2","score":0.8949999809265137},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.7480000257492065},{"id":"https://openalex.org/keywords/steroid-resistance","display_name":"steroid resistance","score":0.8140000104904175},{"id":"https://openalex.org/keywords/glucocorticoid-resistance","display_name":"glucocorticoid resistance","score":0.7839999794960022},{"id":"https://openalex.org/keywords/interleukin-7","display_name":"IL-7","score":0.843999981880188},{"id":"https://openalex.org/keywords/thymic-stromal-lymphopoietin","display_name":"thymic stromal lymphopoietin","score":0.9679999947547913},{"id":"https://openalex.org/keywords/stat5-signaling","display_name":"STAT5 signaling","score":0.9660000205039978},{"id":"https://openalex.org/keywords/plzf","display_name":"PLZF","score":0.9779999852180481},{"id":"https://openalex.org/keywords/il-5","display_name":"IL-5","score":0.703000009059906},{"id":"https://openalex.org/keywords/glucocorticoid-receptor","display_name":"glucocorticoid receptor","score":0.859000027179718},{"id":"https://openalex.org/keywords/tofacitinib","display_name":"tofacitinib","score":0.8569999933242798},{"id":"https://openalex.org/keywords/bronchoalveolar-lavage","display_name":"bronchoalveolar lavage","score":0.8790000081062317},{"id":"https://openalex.org/keywords/airway-inflammation","display_name":"airway inflammation","score":0.609000027179718}],"concepts":[{"id":"https://openalex.org/C47742525","wikidata":"https://www.wikidata.org/wiki/Q13418826","display_name":"Innate lymphoid cell","level":4,"score":0.6445854902267456},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5150132179260254},{"id":"https://openalex.org/C123982805","wikidata":"https://www.wikidata.org/wiki/Q6046964","display_name":"Interleukin-7 receptor","level":5,"score":0.47677069902420044},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4718206822872162},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46493762731552124},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4561154544353485},{"id":"https://openalex.org/C2779391668","wikidata":"https://www.wikidata.org/wiki/Q4210018","display_name":"STAT5","level":3,"score":0.41723811626434326},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2939401865005493},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2197825014591217},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.19347411394119263},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.13829508423805237},{"id":"https://openalex.org/C79484868","wikidata":"https://www.wikidata.org/wiki/Q5971673","display_name":"IL-2 receptor","level":4,"score":0.09410053491592407}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jaci.2015.12.1038","doi":"https://doi.org/10.1016/j.jaci.2015.12.1038","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaci.2015.12.1038","pdf_url":"http://www.jacionline.org/article/S0091674915027803/pdf","source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jaci.2015.12.1038","doi":"https://doi.org/10.1016/j.jaci.2015.12.1038","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaci.2015.12.1038","pdf_url":"http://www.jacionline.org/article/S0091674915027803/pdf","source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2343348434.pdf","grobid_xml":"https://content.openalex.org/works/W2343348434.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2606710770","https://openalex.org/W4226077034","https://openalex.org/W4200324415","https://openalex.org/W4294124522","https://openalex.org/W2784029682","https://openalex.org/W4200413283","https://openalex.org/W3128730848","https://openalex.org/W4390654079","https://openalex.org/W4250596994","https://openalex.org/W2586572932"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}