{"id":"https://openalex.org/W2342084533","doi":null,"title":"Angelica Sinensis attenuates inflammatory reaction in experimental rat models having spinal cord injury.","display_name":"Angelica Sinensis attenuates inflammatory reaction in experimental rat models having spinal cord injury.","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2342084533","mag":"2342084533","pmid":"https://pubmed.ncbi.nlm.nih.gov/26261562","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4525896"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:3508614","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4525896","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4525896","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089216875","display_name":"Jun Xu","orcid":"https://orcid.org/0000-0002-4133-2533","observed_orcids":["https://orcid.org/0000-0002-4133-2533","https://orcid.org/0009-0003-2360-8094"]},"institutions":[{"id":"https://openalex.org/I4210132813","display_name":"Second Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/03s8txj32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210132813"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Xu","raw_affiliation_strings":["Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University Harbin 150001, China","institution_ids":["https://openalex.org/I4210132813"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050255010","display_name":"E Xiaoqiang","orcid":"https://orcid.org/0009-0000-1109-6974","observed_orcids":["https://orcid.org/0009-0000-1109-6974"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-Qiang E","raw_affiliation_strings":["Department of Orthopedics, The First Affiliated Hospital of Harbin Medical University Harbin 150081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, The First Affiliated Hospital of Harbin Medical University Harbin 150081, China","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hui-Yong Liu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hui-Yong Liu","raw_affiliation_strings":["Department of Orthopedics, Hulan District Hospital of Traditional Chinese Medicine Hulan 150500, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Hulan District Hospital of Traditional Chinese Medicine Hulan 150500, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019315614","display_name":"Jun Tian","orcid":"https://orcid.org/0000-0002-3053-5001","observed_orcids":["https://orcid.org/0000-0002-3053-5001"]},"institutions":[{"id":"https://openalex.org/I4210132813","display_name":"Second Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/03s8txj32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210132813"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Tian","raw_affiliation_strings":["Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University Harbin 150001, China","institution_ids":["https://openalex.org/I4210132813"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101643720","display_name":"Jinglong Yan","orcid":"https://orcid.org/0000-0003-0288-6290","observed_orcids":["https://orcid.org/0000-0003-0288-6290"]},"institutions":[{"id":"https://openalex.org/I4210132813","display_name":"Second Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/03s8txj32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210132813"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing-Long Yan","raw_affiliation_strings":["Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University Harbin 150001, China","institution_ids":["https://openalex.org/I4210132813"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9261,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.84452277,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"8","issue":"6","first_page":"6779","last_page":"85"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/angelica-sinensis","display_name":"Angelica sinensis","score":0.9779999852180481},{"id":"https://openalex.org/keywords/spinal-cord-injury","display_name":"spinal cord injury","score":0.9670000076293945},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.9810000061988831},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.8349999785423279},{"id":"https://openalex.org/keywords/nf-kappab-p65","display_name":"NF-\u03baB p65","score":0.984000027179718},{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":0.9399999976158142},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.9629999995231628},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9890000224113464},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9990000128746033},{"id":"https://openalex.org/keywords/secondary-injury","display_name":"secondary injury","score":0.7360000014305115},{"id":"https://openalex.org/keywords/traditional-chinese-medicine","display_name":"traditional Chinese medicine","score":0.515999972820282}],"concepts":[{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.874948263168335},{"id":"https://openalex.org/C85265743","wikidata":"https://www.wikidata.org/wiki/Q885458","display_name":"Blot","level":3,"score":0.6846808791160583},{"id":"https://openalex.org/C2778334475","wikidata":"https://www.wikidata.org/wiki/Q1415275","display_name":"Spinal cord injury","level":3,"score":0.6745885610580444},{"id":"https://openalex.org/C2779454681","wikidata":"https://www.wikidata.org/wiki/Q2051387","display_name":"Angelica sinensis","level":4,"score":0.5813534259796143},{"id":"https://openalex.org/C3019114686","wikidata":"https://www.wikidata.org/wiki/Q3089676","display_name":"Rat model","level":2,"score":0.5618093609809875},{"id":"https://openalex.org/C2780091945","wikidata":"https://www.wikidata.org/wiki/Q1801578","display_name":"Laminectomy","level":3,"score":0.5423752069473267},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.5226649641990662},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.5067206025123596},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.48572784662246704},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43387091159820557},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.41273033618927},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.41229698061943054},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.412229061126709},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.36142969131469727},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3439444899559021},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29696616530418396},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1747812032699585},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15730023384094238},{"id":"https://openalex.org/C188947578","wikidata":"https://www.wikidata.org/wiki/Q200253","display_name":"Traditional Chinese medicine","level":3,"score":0.08932757377624512},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000072000","descriptor_name":"NF-KappaB Inhibitor alpha","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008517","descriptor_name":"Phytotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009187","descriptor_name":"Myelitis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009187","descriptor_name":"Myelitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009187","descriptor_name":"Myelitis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D009195","descriptor_name":"Peroxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010946","descriptor_name":"Plants, Medicinal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018836","descriptor_name":"Inflammation Mediators","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020672","descriptor_name":"I-kappa B Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029971","descriptor_name":"Angelica sinensis","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051996","descriptor_name":"Transcription Factor RelA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:3508614","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4525896","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:26261562","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26261562","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of clinical and experimental pathology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4525896","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4525896/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Pathol","raw_type":"Text"},{"id":"mag:2342084533","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26261562","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3508614","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4525896","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W202929248","https://openalex.org/W1516370311","https://openalex.org/W1527455107","https://openalex.org/W1540708444","https://openalex.org/W1904051271","https://openalex.org/W1917885463","https://openalex.org/W1964491190","https://openalex.org/W1968793573","https://openalex.org/W1969836507","https://openalex.org/W1970024238","https://openalex.org/W1973273107","https://openalex.org/W1977494370","https://openalex.org/W1991634993","https://openalex.org/W1992813989","https://openalex.org/W1999535636","https://openalex.org/W2018489996","https://openalex.org/W2019108043","https://openalex.org/W2019535758","https://openalex.org/W2020073243","https://openalex.org/W2025590326","https://openalex.org/W2033542384","https://openalex.org/W2034334262","https://openalex.org/W2036905187","https://openalex.org/W2043580058","https://openalex.org/W2044269265","https://openalex.org/W2047369546","https://openalex.org/W2053684855","https://openalex.org/W2061747759","https://openalex.org/W2064711537","https://openalex.org/W2067503499","https://openalex.org/W2107565079","https://openalex.org/W2111392427","https://openalex.org/W2144610142","https://openalex.org/W2162248918","https://openalex.org/W2331176038","https://openalex.org/W2335925695","https://openalex.org/W2370321447","https://openalex.org/W4323285312","https://openalex.org/W7168298221"],"related_works":["https://openalex.org/W2017791186","https://openalex.org/W4396498321","https://openalex.org/W2410654999","https://openalex.org/W2225914140","https://openalex.org/W2144610142","https://openalex.org/W3018872508","https://openalex.org/W2579028310","https://openalex.org/W2758357415","https://openalex.org/W2588855573","https://openalex.org/W2266330491"],"abstract_inverted_index":{"This":[0],"study":[1,79,187],"was":[2,20,45,56,62,70,75,95,113,145,163,170],"aimed":[3],"to":[4,78,115,178],"evaluate":[5],"the":[6,117,152,183,191,203,214],"effect":[7,81,118],"of":[8,36,41,90,108,119,126,154,185,193,216],"Angelica":[9,73,122,148,196],"Sinensis":[10,74,149,197],"on":[11],"experimental":[12],"rat":[13,199],"models":[14,200],"in":[15,34,173,198,212,218],"which":[16],"spinal":[17],"cord":[18],"injury":[19],"induced":[21,63,71],"by":[22,207],"studying":[23],"different":[24],"factors.":[25],"Different":[26],"factors":[27],"causing":[28],"inflammation":[29],"play":[30],"a":[31,49,84],"key":[32],"role":[33],"pathophysiology":[35],"SCI.":[37],"Here":[38],"three":[39],"groups":[40],"rats":[42],"(n=15,":[43],"each":[44],"used).":[46],"These":[47],"included":[48],"sham":[50,142],"control":[51,143],"group":[52,59,66,140,175],"where":[53,60,67],"only":[54],"laminectomy":[55],"performed,":[57],"SCI":[58,61,69,139,208,217],"and":[64,82,92,101,131,141,156,209],"AS/SCI":[65],"although":[68],"but":[72],"also":[76,96,134,164,171],"administered":[77],"its":[80],"draw":[83],"comparison":[85],"with":[86,138],"control.":[87],"The":[88,124],"expression":[89,153],"I-kB\u03b1":[91,155],"NF-kB":[93,157],"p65":[94],"studied":[97],"using":[98],"western":[99,109],"blotting":[100],"after":[102],"recording":[103],"optical":[104],"density":[105],"(OD)":[106],"values":[107],"blots.":[110],"MPO":[111,161],"activity":[112,162],"used":[114],"measure":[116],"20":[120,194],"mg/kg":[121,195],"Sinensis.":[123],"levels":[125],"proinflammatory":[127],"cytokines":[128],"TNF-\u03b1,":[129],"IL-1\u03b2":[130],"IL-6":[132],"were":[133],"studied.":[135],"As":[136],"compared":[137,177],"it":[144],"observed":[146],"that":[147,190],"significantly":[150,165],"reduced":[151,172],"p65,":[158],"(P<0.05),":[159],"while":[160],"reduced.":[166],"Proinflammatory":[167],"cytokine":[168],"level":[169],"treated":[174],"as":[176],"both":[179],"other":[180],"groups.":[181],"On":[182],"basis":[184],"this":[186],"we":[188],"concluded":[189],"use":[192],"can":[201],"attenuate":[202],"secondary":[204],"damage":[205],"caused":[206],"thus":[210],"help":[211],"controlling":[213],"pathology":[215],"rats.":[219]},"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}