{"id":"https://openalex.org/W2341744705","doi":"https://doi.org/10.1056/nejm199411173312002","title":"Lack of Effect of Lovastatin on Restenosis after Coronary Angioplasty","display_name":"Lack of Effect of Lovastatin on Restenosis after Coronary Angioplasty","publication_year":1994,"publication_date":"1994-11-17","ids":{"openalex":"https://openalex.org/W2341744705","doi":"https://doi.org/10.1056/nejm199411173312002","mag":"2341744705","pmid":"https://pubmed.ncbi.nlm.nih.gov/7935702"},"language":"en","primary_location":{"id":"doi:10.1056/nejm199411173312002","doi":"https://doi.org/10.1056/nejm199411173312002","is_oa":true,"landing_page_url":"https://doi.org/10.1056/nejm199411173312002","pdf_url":"https://www.nejm.org/doi/pdf/10.1056/NEJM199411173312002?articleTools=true","source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.nejm.org/doi/pdf/10.1056/NEJM199411173312002?articleTools=true","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088756349","display_name":"William Weintraub","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William S. Weintraub","raw_affiliation_strings":["Department of Medicine, Emory University School of Medicine, Atlanta, GA","Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Emory University School of Medicine, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000212543","display_name":"Stephen J. Boccuzzi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen J. Boccuzzi","raw_affiliation_strings":["Merck Research Laboratories, Rahway, N.J"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Merck Research Laboratories, Rahway, N.J","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057121881","display_name":"J. Larry Klein","orcid":"https://orcid.org/0009-0000-7846-1825","observed_orcids":["https://orcid.org/0009-0000-7846-1825"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Larry Klein","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041401383","display_name":"Andrzej Stanislaw Kosinski","orcid":"https://orcid.org/0000-0003-4151-5185","observed_orcids":["https://orcid.org/0000-0003-4151-5185"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrzej S. Kosinski","raw_affiliation_strings":["Biostatistics Department, Emory University School of Public Health, Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics Department, Emory University School of Public Health, Atlanta","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010753140","display_name":"Spencer B. King","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Spencer B. King","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022504713","display_name":"Russell J. Ivanhoe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405270336","display_name":"AdventHealth","ror":"https://ror.org/00gqase94","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405270336"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell Ivanhoe","raw_affiliation_strings":["Florida Hospital, Orlando"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Florida Hospital, Orlando","institution_ids":["https://openalex.org/I4405270336"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080924780","display_name":"John C. Cedarholm","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John C. Cedarholm","raw_affiliation_strings":["Charlotte Memorial Hospital, Charlotte, N.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charlotte Memorial Hospital, Charlotte, N.C","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055054368","display_name":"Michael E. Stillabower","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael E. Stillabower","raw_affiliation_strings":["Medical Center of Delaware, Wilmington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Center of Delaware, Wilmington","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112152984","display_name":"J. David Talley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. David Talley","raw_affiliation_strings":["University of Louisville, Louisville, Ky"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Louisville, Louisville, Ky","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009066928","display_name":"Samuel J. DeMaio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802366037","display_name":"Baylor University Medical Center","ror":"https://ror.org/03nxfhe13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802366037","https://openalex.org/I4210160418"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel J. DeMaio","raw_affiliation_strings":["Baylor Hospital, Dallas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Baylor Hospital, Dallas","institution_ids":["https://openalex.org/I2802366037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000112460","display_name":"William W. O\u2019Neill","orcid":"https://orcid.org/0000-0002-3062-213X","observed_orcids":["https://orcid.org/0000-0002-3062-213X","https://orcid.org/0009-0000-5896-728X"]},"institutions":[{"id":"https://openalex.org/I4210128757","display_name":"Corewell Health William Beaumont University Hospital","ror":"https://ror.org/03artm726","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210128757","https://openalex.org/I4392738273"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William W. O'Neill","raw_affiliation_strings":["William Beaumont Hospital, Royal Oak, Mich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"William Beaumont Hospital, Royal Oak, Mich","institution_ids":["https://openalex.org/I4210128757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069902398","display_name":"John E. Frazier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John E. Frazier","raw_affiliation_strings":["Allegheny Medical Center, Pittsburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allegheny Medical Center, Pittsburgh","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040252649","display_name":"Caryn L. Cohen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caryn L. Cohen-Bernstein","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077822780","display_name":"David C. Robbins","orcid":"https://orcid.org/0000-0001-6890-440X","observed_orcids":["https://orcid.org/0000-0001-6890-440X"]},"institutions":[{"id":"https://openalex.org/I1285739803","display_name":"MedStar Washington Hospital Center","ror":"https://ror.org/05ry42w04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285739803","https://openalex.org/I86755215"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David C. Robbins","raw_affiliation_strings":["Washington Hospital Center, Washington, D.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington Hospital Center, Washington, D.C","institution_ids":["https://openalex.org/I1285739803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105934578","display_name":"Charles L. Brown","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801405887","display_name":"Piedmont Atlanta Hospital","ror":"https://ror.org/0008s4w86","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801405887","https://openalex.org/I4210153954"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles L. Brown","raw_affiliation_strings":["Piedmont Hospital, Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Piedmont Hospital, Atlanta","institution_ids":["https://openalex.org/I2801405887"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108422661","display_name":"R. Wayne Alexander","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Wayne Alexander","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":30.607,"has_fulltext":false,"cited_by_count":289,"citation_normalized_percentile":{"value":0.99843287,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"331","issue":"20","first_page":"1331","last_page":"1337"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.8765000104904175,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.8765000104904175,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.11230000108480453,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lovastatin","display_name":"lovastatin","score":1.0},{"id":"https://openalex.org/keywords/coronary-restenosis","display_name":"coronary restenosis","score":0.8939999938011169},{"id":"https://openalex.org/keywords/coronary-angioplasty","display_name":"coronary angioplasty","score":0.9229999780654907},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.8790000081062317},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.8730000257492065},{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.7900000214576721},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.7770000100135803},{"id":"https://openalex.org/keywords/acute-vessel-closure","display_name":"acute vessel closure","score":0.7210000157356262}],"concepts":[{"id":"https://openalex.org/C2778283817","wikidata":"https://www.wikidata.org/wiki/Q6590597","display_name":"Restenosis","level":3,"score":0.9382379651069641},{"id":"https://openalex.org/C2780940807","wikidata":"https://www.wikidata.org/wiki/Q417740","display_name":"Lovastatin","level":3,"score":0.924940824508667},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9245646595954895},{"id":"https://openalex.org/C2780326628","wikidata":"https://www.wikidata.org/wiki/Q539795","display_name":"Angioplasty","level":2,"score":0.8841391801834106},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6369368433952332},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.612797200679779},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4767675995826721},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.44842132925987244},{"id":"https://openalex.org/C2994432733","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary disease","level":3,"score":0.41309213638305664},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.3155835270881653},{"id":"https://openalex.org/C2778583881","wikidata":"https://www.wikidata.org/wiki/Q1325542","display_name":"Stent","level":2,"score":0.09069409966468811}],"mesh":[{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008076","descriptor_name":"Cholesterol, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008148","descriptor_name":"Lovastatin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015906","descriptor_name":"Angioplasty, Balloon, Coronary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017023","descriptor_name":"Coronary Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1056/nejm199411173312002","doi":"https://doi.org/10.1056/nejm199411173312002","is_oa":true,"landing_page_url":"https://doi.org/10.1056/nejm199411173312002","pdf_url":"https://www.nejm.org/doi/pdf/10.1056/NEJM199411173312002?articleTools=true","source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:7935702","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7935702","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The New England journal of medicine","raw_type":"Clinical Trial"}],"best_oa_location":{"id":"doi:10.1056/nejm199411173312002","doi":"https://doi.org/10.1056/nejm199411173312002","is_oa":true,"landing_page_url":"https://doi.org/10.1056/nejm199411173312002","pdf_url":"https://www.nejm.org/doi/pdf/10.1056/NEJM199411173312002?articleTools=true","source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2341744705.pdf","grobid_xml":"https://content.openalex.org/works/W2341744705.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W83882887","https://openalex.org/W1815855529","https://openalex.org/W1848464647","https://openalex.org/W1965967389","https://openalex.org/W1981647960","https://openalex.org/W1984462430","https://openalex.org/W1989512766","https://openalex.org/W2005786831","https://openalex.org/W2017068398","https://openalex.org/W2019440423","https://openalex.org/W2019874790","https://openalex.org/W2044157711","https://openalex.org/W2044226499","https://openalex.org/W2049765270","https://openalex.org/W2054895631","https://openalex.org/W2056154513","https://openalex.org/W2058598807","https://openalex.org/W2059015073","https://openalex.org/W2067998695","https://openalex.org/W2068823281","https://openalex.org/W2076123748","https://openalex.org/W2078563992","https://openalex.org/W2084945610","https://openalex.org/W2088373315","https://openalex.org/W2089900480","https://openalex.org/W2108668893","https://openalex.org/W2114563696","https://openalex.org/W2122099263","https://openalex.org/W2127298401","https://openalex.org/W2132942256","https://openalex.org/W2145799136","https://openalex.org/W2319045997","https://openalex.org/W2324712847","https://openalex.org/W2331959986","https://openalex.org/W2338023005","https://openalex.org/W2474607223"],"related_works":["https://openalex.org/W2037350453","https://openalex.org/W2070985326","https://openalex.org/W2045737848","https://openalex.org/W4214669801","https://openalex.org/W4231330187","https://openalex.org/W1562133246","https://openalex.org/W2076123748","https://openalex.org/W4256257455","https://openalex.org/W7095389318","https://openalex.org/W2398156874"],"abstract_inverted_index":{"BACKGROUND:":[0],"Experimental":[1],"and":[2,130,152,167],"clinical":[3],"observations":[4],"suggest":[5],"that":[6],"lowering":[7,32],"serum":[8,220],"lipid":[9,33],"levels":[10,34],"may":[11],"reduce":[12],"the":[13,22,99,104,126,143,146,153,173,185,188,196,207,219,227,235,241,250,261,291,304,316,320,344,349,354],"risk":[14],"of":[15,24,73,101,103,125,178,184,187,222,233,237,280,297,306,322,346],"restenosis":[16,41,102,302,347],"after":[17,42,230,353],"coronary":[18,90,111,337],"angioplasty.":[19,43],"We":[20],"report":[21],"results":[23],"a":[25,74,88,182,214,295],"prospective,":[26],"randomized,":[27],"double-blind":[28],"trial":[29],"evaluating":[30],"whether":[31],"with":[35,161,201,255,332],"lovastatin":[36,58,147,197,228,262,292,334],"can":[37],"prevent":[38,341],"or":[39,64,277,301,324,342],"delay":[40,343],"METHODS:":[44],"Seven":[45],"to":[46,56,81,118,163],"10":[47],"days":[48],"before":[49,336],"angioplasty,":[50,307],"we":[51],"randomly":[52,116],"assigned":[53,117],"eligible":[54],"patients":[55,115,132,144],"receive":[57,82],"(40":[59],"mg":[60],"orally":[61],"twice":[62],"daily)":[63],"placebo.":[65],"Patients":[66],"who":[67],"underwent":[68,122,133],"successful,":[69,129],"complication-free,":[70],"first-time":[71],"angioplasty":[72,338],"native":[75],"vessel":[76,299],"(the":[77],"index":[78,105],"lesion)":[79],"continued":[80],"therapy":[83],"for":[84],"six":[85,137,231,328,351],"months,":[86],"when":[87],"second":[89,242],"angiogram":[91,243],"was":[92,98,190,244,284],"obtained.":[93],"The":[94],"primary":[95],"end":[96],"point":[97],"extent":[100],"lesion,":[106],"as":[107,181,199,253,294],"assessed":[108],"by":[109],"quantitative":[110],"arteriography.":[112],"Of":[113],"404":[114],"study":[119],"groups,":[120],"384":[121],"angioplasty;":[123],"354":[124],"procedures":[127],"were":[128,159,269,310],"321":[131],"angiographic":[134],"restudy":[135],"at":[136,303,327],"months.":[138,329],"RESULTS:":[139],"At":[140,170],"base":[141,171],"line,":[142],"in":[145,195,206,218,226,240,249,260,273,290,319,348],"group":[148,155,209,263],"(n":[149,156],"=":[150,157,211,265],"203)":[151],"placebo":[154,208,251],"201)":[158],"similar":[160],"respect":[162],"demographic":[164],"clinical,":[165],"angiographic,":[166],"laboratory":[168],"characteristics.":[169],"line":[172],"mean":[174],"(+/-":[175],"SD)":[176],"degree":[177],"stenosis,":[179],"expressed":[180],"percentage":[183],"diameter":[186,276],"vessel,":[189],"64":[191],"+/-":[192,203,246,257],"11":[193,204],"percent":[194,205,216,248,259],"group,":[198,229,252,293],"compared":[200,254],"63":[202],"(P":[210,264],"0.22).":[212],"Despite":[213],"42":[215],"reduction":[217],"level":[221],"low-density":[223],"lipoprotein":[224],"cholesterol":[225],"months":[232,352],"treatment":[234],"amount":[236],"stenosis":[238],"seen":[239],"46":[245],"20":[247],"44":[256],"21":[258],"0.50).":[266],"Similarly,":[267],"there":[268,309],"no":[270,311],"significant":[271],"differences":[272,314],"minimal":[274],"luminal":[275],"other":[278,312],"measures":[279],"restenosis.":[281],"A":[282],"trend":[283],"noted":[285],"toward":[286],"more":[287],"myocardial":[288],"infarctions":[289],"result":[296],"acute":[298],"closure":[300],"site":[305],"but":[308],"important":[313],"between":[315],"two":[317],"groups":[318],"frequency":[321],"fatal":[323],"nonfatal":[325],"events":[326],"CONCLUSIONS:":[330],"Treatment":[331],"high-dose":[333],"initiated":[335],"does":[339],"not":[340],"process":[345],"first":[350],"procedure.":[355]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}