{"id":"https://openalex.org/W2341663707","doi":"https://doi.org/10.1371/journal.pgen.1005924","title":"BRR2a Affects Flowering Time via FLC Splicing","display_name":"BRR2a Affects Flowering Time via FLC Splicing","publication_year":2016,"publication_date":"2016-04-21","ids":{"openalex":"https://openalex.org/W2341663707","doi":"https://doi.org/10.1371/journal.pgen.1005924","mag":"2341663707","pmid":"https://pubmed.ncbi.nlm.nih.gov/27100965","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4839602"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pgen.1005924","doi":"https://doi.org/10.1371/journal.pgen.1005924","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pgen.1005924","pdf_url":"https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005924&type=printable","source":{"id":"https://openalex.org/S103870658","display_name":"PLoS Genetics","issn_l":"1553-7390","issn":["1553-7390","1553-7404"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Genetics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005924&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025651716","display_name":"Walid Mahrez","orcid":"https://orcid.org/0000-0003-3771-5221","observed_orcids":["https://orcid.org/0000-0003-3771-5221"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH","SE"],"is_corresponding":false,"raw_author_name":"Walid Mahrez","raw_affiliation_strings":["ETH Z\u00fcrich, Department of Biology, Z\u00fcrich, Switzerland","Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z\u00fcrich, Department of Biology, Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I35440088"]},{"raw_affiliation_string":"Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017262355","display_name":"Juhyun Shin","orcid":"https://orcid.org/0000-0003-3434-658X","observed_orcids":["https://orcid.org/0000-0003-3434-658X"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Juhyun Shin","raw_affiliation_strings":["Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033777100","display_name":"Rafael Mu\u00f1oz\u2010Viana","orcid":"https://orcid.org/0000-0002-1363-6978","observed_orcids":["https://orcid.org/0000-0002-1363-6978"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Rafael Mu\u00f1oz-Viana","raw_affiliation_strings":["Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-1363-6978","affiliations":[{"raw_affiliation_string":"Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004244154","display_name":"Duarte D. Figueiredo","orcid":"https://orcid.org/0000-0001-7990-3592","observed_orcids":["https://orcid.org/0000-0001-7990-3592"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Duarte D. Figueiredo","raw_affiliation_strings":["Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden"],"raw_orcid":"https://orcid.org/0000-0001-7990-3592","affiliations":[{"raw_affiliation_string":"Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053753341","display_name":"Minerva S. Trejo\u2010Arellano","orcid":"https://orcid.org/0000-0002-1982-3475","observed_orcids":["https://orcid.org/0000-0002-1982-3475"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Minerva S. Trejo-Arellano","raw_affiliation_strings":["Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-1982-3475","affiliations":[{"raw_affiliation_string":"Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087951549","display_name":"Vivien Exner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Vivien Exner","raw_affiliation_strings":["ETH Z\u00fcrich, Department of Biology, Z\u00fcrich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z\u00fcrich, Department of Biology, Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081227557","display_name":"Alexey Siretskiy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Alexey Siretskiy","raw_affiliation_strings":["Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006955632","display_name":"Wilhelm Gruissem","orcid":"https://orcid.org/0000-0002-1872-2998","observed_orcids":["https://orcid.org/0000-0002-1872-2998"]},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Wilhelm Gruissem","raw_affiliation_strings":["ETH Z\u00fcrich, Department of Biology, Z\u00fcrich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-1872-2998","affiliations":[{"raw_affiliation_string":"ETH Z\u00fcrich, Department of Biology, Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049291766","display_name":"Claudia K\u00f6hler","orcid":"https://orcid.org/0000-0002-2619-4857","observed_orcids":["https://orcid.org/0000-0002-2619-4857"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Claudia K\u00f6hler","raw_affiliation_strings":["Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079839702","display_name":"Lars Hennig","orcid":"https://orcid.org/0000-0002-6645-1862","observed_orcids":["https://orcid.org/0000-0002-6645-1862"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Lars Hennig","raw_affiliation_strings":["Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-6645-1862","affiliations":[{"raw_affiliation_string":"Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant Biology, Uppsala, Sweden","institution_ids":["https://openalex.org/I298625061"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5079839702"],"corresponding_institution_ids":["https://openalex.org/I298625061"],"apc_list":{"value":3043,"currency":"USD","value_usd":3043},"apc_paid":{"value":1976,"currency":"EUR","value_usd":2131},"fwci":7.5119,"has_fulltext":true,"cited_by_count":83,"citation_normalized_percentile":{"value":0.97163971,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"12","issue":"4","first_page":"e1005924","last_page":"e1005924"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.6772000193595886,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.6772000193595886,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.31619998812675476,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11927","display_name":"Plant Reproductive Biology","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flowering-time","display_name":"flowering time","score":0.718999981880188},{"id":"https://openalex.org/keywords/rna-splicing","display_name":"RNA splicing","score":0.8619999885559082},{"id":"https://openalex.org/keywords/spliceosome","display_name":"spliceosome","score":0.8920000195503235},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.8820000290870667},{"id":"https://openalex.org/keywords/early-flowering-mutant","display_name":"early flowering mutant","score":0.7609999775886536},{"id":"https://openalex.org/keywords/intron-retention","display_name":"intron retention","score":0.8240000009536743},{"id":"https://openalex.org/keywords/chromatin","display_name":"chromatin","score":0.38999998569488525},{"id":"https://openalex.org/keywords/h3k4me1","display_name":"H3K4me1","score":0.8669999837875366},{"id":"https://openalex.org/keywords/cg-methylation","display_name":"CG methylation","score":0.8140000104904175},{"id":"https://openalex.org/keywords/h3k27me3","display_name":"H3K27me3","score":0.9950000047683716},{"id":"https://openalex.org/keywords/h3k36me3","display_name":"H3K36me3","score":0.9950000047683716},{"id":"https://openalex.org/keywords/ft","display_name":"FT","score":0.7089999914169312},{"id":"https://openalex.org/keywords/soc1","display_name":"SOC1","score":0.968999981880188},{"id":"https://openalex.org/keywords/post-transcriptional-regulation","display_name":"post-transcriptional regulation","score":0.7429999709129333}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8557252287864685},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.8215906620025635},{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.8024455308914185},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.7210111618041992},{"id":"https://openalex.org/C40000846","wikidata":"https://www.wikidata.org/wiki/Q915868","display_name":"Spliceosome","level":5,"score":0.6618524193763733},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6614468097686768},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5516494512557983},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.4530385136604309},{"id":"https://openalex.org/C64962909","wikidata":"https://www.wikidata.org/wiki/Q5611160","display_name":"Group II intron","level":5,"score":0.4366548955440521},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.42875584959983826},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.4158138632774353},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.303122878074646}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007438","descriptor_name":"Introns","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012326","descriptor_name":"RNA Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026161","descriptor_name":"MADS Domain Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D035264","descriptor_name":"Flowers","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1371/journal.pgen.1005924","doi":"https://doi.org/10.1371/journal.pgen.1005924","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pgen.1005924","pdf_url":"https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005924&type=printable","source":{"id":"https://openalex.org/S103870658","display_name":"PLoS Genetics","issn_l":"1553-7390","issn":["1553-7390","1553-7404"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Genetics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4839602","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4839602","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Genet","raw_type":"Text"},{"id":"pmid:27100965","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27100965","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS genetics","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:722796142cfe43e2bc1bf3da1ea65f35","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/722796142cfe43e2bc1bf3da1ea65f35","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics, Vol 12, Iss 4, p e1005924 (2016)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/3946584","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/BRR2a_Affects_Flowering_Time_via_i_FLC_i_Splicing/3946584","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pure.mpg.de:item_3282184","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/21.11116/0000-0007-DEFA-6","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:www.research-collection.ethz.ch:20.500.11850/116126","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.11850/116126","pdf_url":null,"source":{"id":"https://openalex.org/S4306402302","display_name":"Repository for Publications and Research Data (ETH Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I35440088","host_organization_name":"ETH Zurich","host_organization_lineage":["https://openalex.org/I35440088"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics, 12 (4)","raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.3929/ethz-b-000116126","doi":"https://doi.org/10.3929/ethz-b-000116126","is_oa":true,"landing_page_url":"https://doi.org/10.3929/ethz-b-000116126","pdf_url":null,"source":{"id":"https://openalex.org/S7407051236","display_name":"ETH Z\u00fcrich Research Collection","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1371/journal.pgen.1005924","doi":"https://doi.org/10.1371/journal.pgen.1005924","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pgen.1005924","pdf_url":"https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005924&type=printable","source":{"id":"https://openalex.org/S103870658","display_name":"PLoS Genetics","issn_l":"1553-7390","issn":["1553-7390","1553-7404"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Genetics","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2952237611","display_name":null,"funder_award_id":"2012-1519","funder_id":"https://openalex.org/F4320321033","funder_display_name":"Svenska Forskningsr\u00e5det Formas"},{"id":"https://openalex.org/G552744968","display_name":null,"funder_award_id":"KAW 2012.0087","funder_id":"https://openalex.org/F4320322327","funder_display_name":"Knut och Alice Wallenbergs Stiftelse"},{"id":"https://openalex.org/G6668042044","display_name":"Mechanisms of Polycomb group protein-mediated genome programming in Arabidopsis","funder_award_id":"2011-05010","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G7536721123","display_name":null,"funder_award_id":"CTS 11:189","funder_id":"https://openalex.org/F4320321501","funder_display_name":"Carl Tryggers Stiftelse f\u00f6r Vetenskaplig Forskning"},{"id":"https://openalex.org/G8678169954","display_name":"Mechanisms of  vernalization","funder_award_id":"127358","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G993172209","display_name":null,"funder_award_id":"230-2012-1519","funder_id":"https://openalex.org/F4320321033","funder_display_name":"Svenska Forskningsr\u00e5det Formas"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320321033","display_name":"Svenska Forskningsr\u00e5det Formas","ror":"https://ror.org/03pjs1y45"},{"id":"https://openalex.org/F4320321501","display_name":"Carl Tryggers Stiftelse f\u00f6r Vetenskaplig Forskning","ror":"https://ror.org/048p4fn82"},{"id":"https://openalex.org/F4320322327","display_name":"Knut och Alice Wallenbergs Stiftelse","ror":"https://ror.org/004hzzk67"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2341663707.pdf","grobid_xml":"https://content.openalex.org/works/W2341663707.grobid-xml"},"referenced_works_count":112,"referenced_works":["https://openalex.org/W1197402732","https://openalex.org/W1413417492","https://openalex.org/W1492034352","https://openalex.org/W1572357774","https://openalex.org/W1928292542","https://openalex.org/W1930039709","https://openalex.org/W1936136232","https://openalex.org/W1967227300","https://openalex.org/W1968072881","https://openalex.org/W1975009102","https://openalex.org/W1979491817","https://openalex.org/W1979863623","https://openalex.org/W1980298695","https://openalex.org/W1980432902","https://openalex.org/W1984962092","https://openalex.org/W1993377849","https://openalex.org/W1993928608","https://openalex.org/W1994257433","https://openalex.org/W2000934711","https://openalex.org/W2002557938","https://openalex.org/W2002900187","https://openalex.org/W2005370601","https://openalex.org/W2009221497","https://openalex.org/W2009514731","https://openalex.org/W2013146348","https://openalex.org/W2015195844","https://openalex.org/W2018574323","https://openalex.org/W2020129853","https://openalex.org/W2021249791","https://openalex.org/W2024071877","https://openalex.org/W2024848067","https://openalex.org/W2025317003","https://openalex.org/W2029730517","https://openalex.org/W2031922425","https://openalex.org/W2035736338","https://openalex.org/W2036764180","https://openalex.org/W2037624251","https://openalex.org/W2038549730","https://openalex.org/W2039521726","https://openalex.org/W2040278443","https://openalex.org/W2042459848","https://openalex.org/W2045952340","https://openalex.org/W2055598782","https://openalex.org/W2056431625","https://openalex.org/W2061538357","https://openalex.org/W2063954820","https://openalex.org/W2066672169","https://openalex.org/W2067192695","https://openalex.org/W2072274987","https://openalex.org/W2075301397","https://openalex.org/W2076992915","https://openalex.org/W2077721732","https://openalex.org/W2081468353","https://openalex.org/W2083520043","https://openalex.org/W2084799820","https://openalex.org/W2085971867","https://openalex.org/W2090819625","https://openalex.org/W2094350388","https://openalex.org/W2095861170","https://openalex.org/W2096546758","https://openalex.org/W2097640253","https://openalex.org/W2097664345","https://openalex.org/W2098832713","https://openalex.org/W2100680386","https://openalex.org/W2100849967","https://openalex.org/W2102275974","https://openalex.org/W2103483475","https://openalex.org/W2104618447","https://openalex.org/W2104630820","https://openalex.org/W2105037453","https://openalex.org/W2105434771","https://openalex.org/W2107787782","https://openalex.org/W2107900085","https://openalex.org/W2109322710","https://openalex.org/W2110065044","https://openalex.org/W2110776599","https://openalex.org/W2114800743","https://openalex.org/W2123721334","https://openalex.org/W2124946360","https://openalex.org/W2124985265","https://openalex.org/W2125889285","https://openalex.org/W2131271579","https://openalex.org/W2132632499","https://openalex.org/W2133757548","https://openalex.org/W2134526812","https://openalex.org/W2136673025","https://openalex.org/W2137017469","https://openalex.org/W2137979475","https://openalex.org/W2138009545","https://openalex.org/W2140659212","https://openalex.org/W2140729960","https://openalex.org/W2141524808","https://openalex.org/W2142663409","https://openalex.org/W2146281024","https://openalex.org/W2146547152","https://openalex.org/W2152326614","https://openalex.org/W2153849837","https://openalex.org/W2154972412","https://openalex.org/W2155336429","https://openalex.org/W2156498074","https://openalex.org/W2156726420","https://openalex.org/W2157070284","https://openalex.org/W2157488912","https://openalex.org/W2158235544","https://openalex.org/W2163516449","https://openalex.org/W2167432290","https://openalex.org/W2169343403","https://openalex.org/W2171454015","https://openalex.org/W2179438025","https://openalex.org/W2233726922","https://openalex.org/W2970966356","https://openalex.org/W7075701559"],"related_works":["https://openalex.org/W2022750901","https://openalex.org/W2111923794","https://openalex.org/W4365512434","https://openalex.org/W2915663784","https://openalex.org/W2583168760","https://openalex.org/W4292449048","https://openalex.org/W2055598782","https://openalex.org/W2116680224","https://openalex.org/W2755336464","https://openalex.org/W4416697797"],"abstract_inverted_index":{"Several":[0],"pathways":[1],"control":[2,30,153],"time":[3,29,42,89],"to":[4,40,124,152,212],"flowering":[5,28,41,53,88,126],"in":[6,31,71,78,84,101,105,127,147],"Arabidopsis":[7,51,73],"thaliana":[8],"through":[9],"transcriptional":[10],"and":[11,68,82,108,121,130,160,165,169,204,206],"posttranscriptional":[12],"gene":[13,90],"regulation.":[14],"In":[15,47],"recent":[16],"years,":[17],"mRNA":[18],"processing":[19,86],"has":[20],"gained":[21],"interest":[22],"as":[23],"a":[24,48,138,176,190,196],"critical":[25],"regulator":[26],"of":[27,59,65,87,98,119,141,189,192,198],"plants.":[32],"However,":[33],"the":[34,66,85,148],"molecular":[35],"mechanisms":[36],"linking":[37],"RNA":[38],"splicing":[39,107,188,213],"are":[43,63],"not":[44,144],"well":[45],"understood.":[46],"screen":[49],"for":[50,186],"early":[52,125],"mutants":[54],"we":[55],"identified":[56],"an":[57],"allele":[58],"BRR2a.":[60],"BRR2":[61],"proteins":[62],"components":[64],"spliceosome":[67],"highly":[69],"conserved":[70],"eukaryotes.":[72],"BRR2a":[74,102,182],"is":[75,183,209],"ubiquitously":[76],"expressed":[77],"all":[79],"analyzed":[80],"tissues":[81],"involved":[83],"transcripts,":[91],"most":[92,210],"notably":[93],"FLC.":[94],"A":[95],"missense":[96],"mutation":[97],"threonine":[99],"895":[100],"caused":[103],"defects":[104],"FLC":[106,111,115,208],"greatly":[109],"reduced":[110],"transcript":[112],"levels.":[113],"Reduced":[114],"expression":[116],"increased":[117],"transcription":[118],"FT":[120],"SOC1":[122],"leading":[123],"both":[128],"short":[129],"long":[131],"days.":[132],"Genome-wide":[133],"experiments":[134],"established":[135],"that":[136,181,207],"only":[137],"small":[139],"set":[140],"introns":[142,156,193],"was":[143],"correctly":[145],"spliced":[146],"brr2a":[149],"mutant.":[150],"Compared":[151],"introns,":[154],"retained":[155],"were":[157,170],"often":[158,171],"shorter":[159],"GC-poor,":[161],"had":[162],"low":[163],"H3K4me1":[164],"CG":[166],"methylation":[167],"levels,":[168],"derived":[172],"from":[173],"genes":[174],"with":[175],"high-H3K27me3-low-H3K36me3":[177],"signature.":[178],"We":[179],"propose":[180],"specifically":[184],"needed":[185],"efficient":[187],"subset":[191],"characterized":[194],"by":[195],"combination":[197],"factors":[199],"including":[200],"intron":[201],"size,":[202],"sequence":[203],"chromatin,":[205],"sensitive":[211],"defects.":[214]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":23},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
