{"id":"https://openalex.org/W2340858846","doi":null,"title":"Ausencia de efecto cognitivo APOE en personas sanas de edad mediana Absence of APOE cognitive effect in healthy middle-aged","display_name":"Ausencia de efecto cognitivo APOE en personas sanas de edad mediana Absence of APOE cognitive effect in healthy middle-aged","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2340858846","mag":"2340858846"},"language":"es","primary_location":{"id":"mag:2340858846","doi":null,"is_oa":false,"landing_page_url":"http://www.scielo.org.co/pdf/anco/v29n3/v29n3a05.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050548469","display_name":"\u00d3scar Sierra Fitzgerald","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u00d3scar Sierra-Fitzgerald","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024254454","display_name":"Guillermo Barreto","orcid":"https://orcid.org/0000-0003-2568-2629","observed_orcids":["https://orcid.org/0000-0003-2568-2629"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guillermo Barreto","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2568-2629","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5068500999","display_name":"Francisco Lopera-Restrepo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francisco Lopera-Restrepo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.8744999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.8744999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11577","display_name":"Cognitive Abilities and Testing","score":0.06340000033378601,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.04089999943971634,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apoe-epsilon4","display_name":"APOE \u03b54","score":0.8690000176429749},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.5580000281333923},{"id":"https://openalex.org/keywords/middle-aged-adults","display_name":"middle-aged adults","score":0.906000018119812},{"id":"https://openalex.org/keywords/healthy-individuals","display_name":"healthy individuals","score":0.6460000276565552},{"id":"https://openalex.org/keywords/visual-short-term-memory","display_name":"visual short-term memory","score":0.8510000109672546},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.7929999828338623},{"id":"https://openalex.org/keywords/dual-task-paradigm","display_name":"dual-task paradigm","score":0.7950000166893005},{"id":"https://openalex.org/keywords/apolipoprotein-e","display_name":"apolipoprotein E","score":0.7310000061988831}],"concepts":[{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.7100786566734314},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5728588104248047},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5548794269561768},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.43613696098327637},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.257002592086792},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1856549084186554},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10899624228477478},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2340858846","doi":null,"is_oa":false,"landing_page_url":"http://www.scielo.org.co/pdf/anco/v29n3/v29n3a05.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1974446762","https://openalex.org/W1976879698","https://openalex.org/W1980870701","https://openalex.org/W1981541008","https://openalex.org/W1983957796","https://openalex.org/W1986144956","https://openalex.org/W1986951455","https://openalex.org/W2002776021","https://openalex.org/W2007376816","https://openalex.org/W2009339691","https://openalex.org/W2010521301","https://openalex.org/W2014342740","https://openalex.org/W2016719751","https://openalex.org/W2031549819","https://openalex.org/W2033336411","https://openalex.org/W2041334242","https://openalex.org/W2051530804","https://openalex.org/W2054798938","https://openalex.org/W2056454824","https://openalex.org/W2069014575","https://openalex.org/W2069330896","https://openalex.org/W2072991506","https://openalex.org/W2082190201","https://openalex.org/W2086787559","https://openalex.org/W2087925678","https://openalex.org/W2097552643","https://openalex.org/W2102496376","https://openalex.org/W2104913592","https://openalex.org/W2111175305","https://openalex.org/W2112957305","https://openalex.org/W2115446900","https://openalex.org/W2130008445","https://openalex.org/W2135063296","https://openalex.org/W2136753870","https://openalex.org/W2141103792","https://openalex.org/W2144225695","https://openalex.org/W2149095485","https://openalex.org/W2152021942","https://openalex.org/W2152541739","https://openalex.org/W2153215481","https://openalex.org/W2171346860"],"related_works":["https://openalex.org/W1524779099","https://openalex.org/W1506261789","https://openalex.org/W3125842667","https://openalex.org/W2404300741","https://openalex.org/W2067314785","https://openalex.org/W7018702994","https://openalex.org/W4322711699","https://openalex.org/W2731023386","https://openalex.org/W2016719751","https://openalex.org/W2093891993"],"abstract_inverted_index":{"SummARy":[0],"IntroductIon.":[1],"Despite":[2],"the":[3,13,18,30,53],"known":[4],"structural":[5],"and":[6,42,51,61,78,94],"functional":[7],"brain":[8],"changes":[9],"in":[10,34,47,100],"carriers":[11,67],"of":[12,23,45,65,68,75,82,86,91,97,103],"apolipotrein":[14],"e4":[15,69],"(APOE)":[16],"allele,":[17],"findings":[19],"on":[20],"cognitive":[21,32],"functioning":[22],"these":[24],"individuals":[25,36],"are":[26],"mixed.":[27],"objectIve.":[28],"Evaluate":[29],"APOE-dependent":[31],"effect":[33],"middle-aged":[35],"with":[37,84],"traditional":[38],"neurop-":[39],"sychological":[40],"tests":[41],"experimental":[43],"tasks":[44],"binding":[46],"short-term":[48],"visual":[49],"memory":[50,55],"from":[52],"working":[54],"by":[56],"dual":[57],"task":[58],"paradigm.":[59],"MaterIals":[60],"Methods.":[62],"The":[63],"performance":[64],"25":[66],"alleles":[70],"was":[71],"compared":[72],"(mean":[73,89],"age":[74,90],"38.6":[76],"years":[77,81,93],"9.7":[79],"mean":[80],"schooling)":[83],"that":[85],"38":[87],"non-carriers":[88],"39.5":[92],"average":[95],"education":[96],"11":[98],"years)":[99],"both":[101],"types":[102],"tests.":[104]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}