{"id":"https://openalex.org/W2340445826","doi":null,"title":"Metabolic monitoring in patients undergoing cardiac surgery using intravascular microdialysis","display_name":"Metabolic monitoring in patients undergoing cardiac surgery using intravascular microdialysis","publication_year":2016,"publication_date":"2016-04-22","ids":{"openalex":"https://openalex.org/W2340445826","mag":"2340445826"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/26922007","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Metabolic_monitoring_in_patients_undergoing_cardiac_surgery_using_intravascular_microdialysis/26922007","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10616/45080","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060729485","display_name":"Fanny Schierenbeck","orcid":"https://orcid.org/0009-0003-2417-8575","observed_orcids":["https://orcid.org/0009-0003-2417-8575"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Fanny Schierenbeck","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5060729485"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.021400000900030136,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.012000000104308128,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiac-surgery","display_name":"cardiac surgery","score":0.7850000262260437},{"id":"https://openalex.org/keywords/blood-glucose-monitoring","display_name":"blood glucose monitoring","score":0.7919999957084656},{"id":"https://openalex.org/keywords/lactate-monitoring","display_name":"lactate monitoring","score":0.9160000085830688},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.8799999952316284},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.7519999742507935},{"id":"https://openalex.org/keywords/hypoglycemia","display_name":"hypoglycemia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/glycemic-variability","display_name":"glycemic variability","score":0.984000027179718},{"id":"https://openalex.org/keywords/continuous-glucose-monitoring","display_name":"continuous glucose monitoring","score":0.6850000023841858},{"id":"https://openalex.org/keywords/central-venous-catheters","display_name":"central venous catheters","score":0.8640000224113464},{"id":"https://openalex.org/keywords/intensive-care-unit","display_name":"intensive care unit","score":0.6200000047683716},{"id":"https://openalex.org/keywords/postoperative-care","display_name":"postoperative care","score":0.6489999890327454},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.7919999957084656},{"id":"https://openalex.org/keywords/sensor-accuracy-and-reliability","display_name":"sensor accuracy and reliability","score":0.3790000081062317}],"concepts":[{"id":"https://openalex.org/C50156730","wikidata":"https://www.wikidata.org/wiki/Q3856966","display_name":"Microdialysis","level":3,"score":0.899444580078125},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5958203077316284},{"id":"https://openalex.org/C2778789114","wikidata":"https://www.wikidata.org/wiki/Q235007","display_name":"Cardiac surgery","level":2,"score":0.5249688029289246},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3566545248031616},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3127058446407318},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24316492676734924},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/26922007","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Metabolic_monitoring_in_patients_undergoing_cardiac_surgery_using_intravascular_microdialysis/26922007","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:openarchive.ki.se:10616/45080","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/45080","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2340445826","doi":null,"is_oa":false,"landing_page_url":"https://openarchive.ki.se/xmlui/handle/10616/45080","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:openarchive.ki.se:10616/45080","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/45080","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":94,"referenced_works":["https://openalex.org/W132531958","https://openalex.org/W1601097124","https://openalex.org/W1616394907","https://openalex.org/W1810606367","https://openalex.org/W1967265218","https://openalex.org/W1972352298","https://openalex.org/W1975257851","https://openalex.org/W1976399591","https://openalex.org/W1976490895","https://openalex.org/W1980717583","https://openalex.org/W1981121993","https://openalex.org/W1981870107","https://openalex.org/W1988221993","https://openalex.org/W1997874406","https://openalex.org/W1999231148","https://openalex.org/W2002506098","https://openalex.org/W2009177416","https://openalex.org/W2010549230","https://openalex.org/W2011217254","https://openalex.org/W2011857426","https://openalex.org/W2015795623","https://openalex.org/W2024151788","https://openalex.org/W2027015828","https://openalex.org/W2027702390","https://openalex.org/W2029237990","https://openalex.org/W2029491963","https://openalex.org/W2034084425","https://openalex.org/W2044437167","https://openalex.org/W2052271188","https://openalex.org/W2058406121","https://openalex.org/W2059670330","https://openalex.org/W2062055324","https://openalex.org/W2066526251","https://openalex.org/W2066944661","https://openalex.org/W2072408018","https://openalex.org/W2073196712","https://openalex.org/W2074745934","https://openalex.org/W2075443305","https://openalex.org/W2076780152","https://openalex.org/W2078109730","https://openalex.org/W2090526906","https://openalex.org/W2092998122","https://openalex.org/W2095028721","https://openalex.org/W2097346269","https://openalex.org/W2097816357","https://openalex.org/W2103079216","https://openalex.org/W2107545755","https://openalex.org/W2108699123","https://openalex.org/W2108880291","https://openalex.org/W2111127564","https://openalex.org/W2111883268","https://openalex.org/W2113662426","https://openalex.org/W2114075528","https://openalex.org/W2115285670","https://openalex.org/W2116907416","https://openalex.org/W2120226132","https://openalex.org/W2125163474","https://openalex.org/W2126100568","https://openalex.org/W2128156839","https://openalex.org/W2129225365","https://openalex.org/W2129681898","https://openalex.org/W2130075376","https://openalex.org/W2131556432","https://openalex.org/W2133453263","https://openalex.org/W2133635544","https://openalex.org/W2134369433","https://openalex.org/W2139706988","https://openalex.org/W2139869529","https://openalex.org/W2142123151","https://openalex.org/W2143293940","https://openalex.org/W2143623075","https://openalex.org/W2143668689","https://openalex.org/W2144499458","https://openalex.org/W2145053281","https://openalex.org/W2145068031","https://openalex.org/W2148654972","https://openalex.org/W2148706741","https://openalex.org/W2153014880","https://openalex.org/W2153235420","https://openalex.org/W2153654864","https://openalex.org/W2157775267","https://openalex.org/W2160710729","https://openalex.org/W2162268531","https://openalex.org/W2164334584","https://openalex.org/W2165256339","https://openalex.org/W2166004381","https://openalex.org/W2167788046","https://openalex.org/W2168603964","https://openalex.org/W2168718820","https://openalex.org/W2169968309","https://openalex.org/W2313326603","https://openalex.org/W2320349682","https://openalex.org/W2330296161","https://openalex.org/W6892271164"],"related_works":["https://openalex.org/W2098572079","https://openalex.org/W2073997265","https://openalex.org/W4406349069","https://openalex.org/W2336199585","https://openalex.org/W2001945801","https://openalex.org/W2002249321","https://openalex.org/W1577199578","https://openalex.org/W2058562160","https://openalex.org/W2509719597","https://openalex.org/W2046001200"],"abstract_inverted_index":{"Critically":[0],"ill":[1,106,578],"patients":[2,4,153,379,542,579,703,760],"and":[3,12,35,61,85,120,141,150,186,199,218,260,270,273,293,319,390,403,419,430,446,479,500,531,539,546,568,587,616,619],"undergoing":[5,154,543,704,761],"cardiac":[6,155,382,544,621,705,762],"surgery":[7,156],"often":[8],"experience":[9],"hyperglycemia,":[10],"hypoglycemia":[11,36],"glycemic":[13,42,57],"variability":[14,43],"(fluctuating":[15],"blood":[16,129,276,291,339,423,448,585,640,667,730],"glucose":[17,63,119,149,217,269,292,318,449,462,483,538,586,615,641,668,731,756],"concentrations),":[18],"all":[19],"of":[20,70,88,148,216,301,304,322,345,392,432,456,498,507,537,561,584,592,596,637,664,725,752],"which":[21,97,189,362,374,410],"have":[22],"been":[23,45,99],"associated":[24],"with":[25,341,459,676],"adverse":[26],"outcomes.":[27],"Glycemic":[28],"control":[29,583],"aimed":[30,133],"at":[31,40,134],"avoiding":[32],"both":[33],"hyper-":[34],"as":[37,39,81,232,284,451,453,610],"well":[38,452],"minimizing":[41],"has":[44,98],"shown":[46,100,332],"to":[47,55,93,101,169,223,250,275,311,333,381,476,493,549],"be":[48,334,494],"beneficial":[49,73],"in":[50,104,122,152,160,225,237,263,337,350,358,361,368,378,407,421,438,468,496,505,509,519,541,553,576,702,733,759],"these":[51],"patients.":[52,107],"In":[53,241,296,425],"order":[54],"enable":[56],"control,":[58],"a":[59,82,111,139,174,184,191,196,200,208,238,251,264,312,342,347,369,457,460,477,529,550,565,611,638,665,672],"safe":[60,530],"reliable":[62,567],"monitoring":[64,69,147,338,422,484,536,642,669,701,732,757],"system":[65,330,415,435,473,485,490,517,552,643,670],"is":[66,72,91,110,181,211,235,375,528,547],"required.":[67],"Additionally,":[68],"lactate":[71,77,89,121,151,219,271,294,320,399,540,588,617,700],"since":[74],"an":[75,285,439,677,735],"elevated":[76],"level":[78],"may":[79],"serve":[80],"warning":[83],"signal,":[84],"the":[86,123,126,161,214,226,230,233,244,281,299,302,305,323,351,363,388,393,413,428,433,465,471,502,510,515,559,562,581],"knowledge":[87],"concentration":[90,463],"necessary":[92],"guide":[94],"lactate-reducing":[95],"treatment,":[96],"improve":[102],"outcome":[103],"critically":[105,577],"Intravascular":[108,608],"microdialysis":[109,137,179,202,246,282,306,328,364,394,414,434,472,489,527,609,679,697,727,765],"technique":[112,355],"that":[113,412,525],"can":[114],"monitor":[115],"small":[116,192],"molecules":[117],"like":[118],"bloodstream":[124,231],"without":[125],"need":[127],"for":[128,145,268,289,534,574,580,589,613,698,728],"sampling.":[130],"This":[131,278,522],"thesis":[132,523],"developing":[135],"intravascular":[136,178,245,526,696,726,764],"into":[138,173],"verified":[140,280,481],"accepted":[142],"clinical":[143,287,352,503],"method":[144,180,288,533,612],"continuous":[146,327,482,535,639,666,699,729,755],"requiring":[157],"postoperative":[158],"treatment":[159],"intensive":[162,511],"care":[163,512],"unit.":[164],"Furthermore,":[165],"another":[166],"aim":[167],"was":[168,248,258,308,331,356,366,416,474,491,572],"incorporate":[170],"this":[171,206,520,554],"technology":[172],"standard":[175,370,570],"procedure.":[176],"The":[177,255,326,354,384,396,488],"based":[182],"on":[183,398,558],"new":[185],"innovative":[187],"technology,":[188],"involves":[190],"compartment":[193,303],"located":[194],"between":[195],"catheter":[197,234,307,675],"body":[198],"covering":[201],"membrane.":[203],"By":[204],"perfusing":[205],"compartment,":[207],"dialysate":[209,256,266,324],"fluid":[210,257],"produced":[212],"wherein":[213],"concentrations":[215,272,321],"are":[220],"theoretically":[221],"equal":[222],"those":[224],"surrounding":[227],"tissue,":[228],"i.e.":[229],"placed":[236,486],"central":[239,371,645,673],"vein.":[240],"Study":[242,297,359,408,426,469],"I,":[243],"concept":[247,283],"applied":[249,377],"single-":[252],"lumen":[253],"catheter.":[254,466],"collected":[259],"intermittently":[261],"analyzed":[262],"separate":[265],"analyzer":[267],"compared":[274,475],"samples.":[277],"study":[279],"efficient":[286,420],"measuring":[290,614],"levels.":[295],"II,":[298],"outlet":[300],"directly":[309],"connected":[310],"recently":[313],"developed":[314,573],"sensor,":[315],"continuously":[316],"analyzing":[317],"fluid.":[325],"catheter-sensor":[329],"very":[335],"accurate":[336,418,532],"glucose,":[340],"lag":[343],"time":[344],"only":[346],"few":[348],"minutes":[349],"setting.":[353,556],"improved":[357],"III,":[360],"membrane":[365],"integrated":[367,678],"venous":[372,646,674],"catheter,":[373],"routinely":[376],"subjected":[380],"surgery.":[383,622],"results":[385,560],"further":[386],"demonstrated":[387,411],"accuracy":[389,429,499],"reliability":[391],"system.":[395],"data":[397],"from":[400],"Studies":[401],"II":[402],"III":[404],"were":[405,436],"processed":[406],"IV,":[409],"also":[417],"lactate.":[424],"V,":[427],"responsiveness":[431],"confirmed":[437],"animal":[440,736],"model":[441],"during":[442,454,618],"extreme":[443],"hypoglycemic":[444],"conditions":[445],"rapid":[447],"oscillations,":[450],"infusion":[455],"solution":[458],"high":[461],"via":[464],"Finally":[467],"VI,":[470],"certified":[478,569],"clinically":[480],"subcutaneously.":[487],"found":[492],"superior":[495,548],"terms":[497,506],"met":[501],"standards":[504],"safety":[508],"unit,":[513],"while":[514],"subcutaneous":[516,551,767],"failed":[518],"respect.":[521],"demonstrates":[524],"surgery,":[545],"specific":[555],"Based":[557],"included":[563],"studies,":[564],"safe,":[566],"procedure":[571],"use":[575],"pertinent":[582],"early":[590],"detection":[591],"metabolic":[593],"derangement.":[594],"List":[595],"scientific":[597],"papers":[598],"I.":[599],"Mo\u0308ller":[600],"F,":[601,605,631,656,688,717,746],"Liska":[602,634,661,693,722,749],"J,":[603],"Eidhagen":[604],"Franco-Cereceda":[606,632,659,691,720,747],"A.":[607],"after":[620],"J":[623,648,738],"Diabetes":[624,649,681,739],"Sci":[625,650,740],"Technol":[626,651,682,741],"2011;5:1099-1107.":[627],"https://doi.org/10.1177/193229681100500510":[628],"II.":[629],"Schierenbeck":[630,655,687,716,745],"A,":[633,658,660,692,721,748],"J.":[635,662,694,723,750],"Evaluation":[636,663,724],"using":[644,671],"microdialysis.":[647],"2012;6(6):1365\u20131371.":[652],"https://doi.org/10.1177/193229681200600615":[653],"III.":[654],"O\u0308wall":[657],"function.":[680],"Ther":[683],"2013;15(1):26-31.":[684],"https://doi.org/10.1089/dia.2012.0169":[685],"IV.":[686],"Nijsten":[689],"MW,":[690],"Introducing":[695],"surgery:":[706,763],"A":[707],"prospective":[708],"observational":[709],"study.":[710],"Crit":[711],"Care":[712],"2014;18(2):R56.":[713],"https://doi.org/10.1186/cc13808":[714],"V.":[715],"Wallin":[718],"M,":[719],"hypoglycemia:":[734],"model.":[737],"2014;8(4):839-844.":[742],"https://doi.org/10.1177/1932296814532206":[743],"VI.":[744],"Accuracy":[751],"two":[753],"different":[754],"systems":[758],"vs.":[766],"tissue":[768],"monitoring.":[769],"[Submitted]":[770]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
