{"id":"https://openalex.org/W2340366235","doi":"https://doi.org/10.2169/naika.75.341","title":"Plasmapheresis treatment of familial hypercholesterolemia. Methods and evaluation.","display_name":"Plasmapheresis treatment of familial hypercholesterolemia. Methods and evaluation.","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W2340366235","doi":"https://doi.org/10.2169/naika.75.341","mag":"2340366235","pmid":"https://pubmed.ncbi.nlm.nih.gov/3746063"},"language":"ja","primary_location":{"id":"doi:10.2169/naika.75.341","doi":"https://doi.org/10.2169/naika.75.341","is_oa":true,"landing_page_url":"https://doi.org/10.2169/naika.75.341","pdf_url":"https://www.jstage.jst.go.jp/article/naika1913/75/3/75_3_341/_pdf","source":{"id":"https://openalex.org/S4210221755","display_name":"Nihon Naika Gakkai Zasshi","issn_l":"0021-5384","issn":["0021-5384","1883-2083"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Naika Gakkai Zasshi","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/naika1913/75/3/75_3_341/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022444323","display_name":"Akira Yamamoto","orcid":"https://orcid.org/0000-0002-1058-4762","observed_orcids":["https://orcid.org/0000-0002-1058-4762"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akira YAMAMOTO","raw_affiliation_strings":["Department of Etiology, National Cardiovascular Center","Department of Etiology, National Cardiovascular Center, Suita"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Etiology, National Cardiovascular Center","institution_ids":[]},{"raw_affiliation_string":"Department of Etiology, National Cardiovascular Center, Suita","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034922501","display_name":"Toshiro Kikkawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117281","display_name":"Sumitomo Hospital","ror":"https://ror.org/02m9ewz37","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210117281"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshiro KIKAWA","raw_affiliation_strings":["Department of Medicine, Sumitomo Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Sumitomo Hospital","institution_ids":["https://openalex.org/I4210117281"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.25737339,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"75","issue":"3","first_page":"341","last_page":"346"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasmapheresis","display_name":"plasmapheresis","score":0.9739999771118164},{"id":"https://openalex.org/keywords/familial-hypercholesterolemia","display_name":"familial hypercholesterolemia","score":1.0},{"id":"https://openalex.org/keywords/hypercholesterolemia-treatment","display_name":"hypercholesterolemia treatment","score":0.8640000224113464},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.6489999890327454},{"id":"https://openalex.org/keywords/treatment-evaluation","display_name":"treatment evaluation","score":0.5799999833106995}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9749945402145386},{"id":"https://openalex.org/C2778842783","wikidata":"https://www.wikidata.org/wiki/Q603502","display_name":"Plasmapheresis","level":3,"score":0.9030054807662964},{"id":"https://openalex.org/C2779120738","wikidata":"https://www.wikidata.org/wiki/Q2711291","display_name":"Familial hypercholesterolemia","level":3,"score":0.8696988821029663},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.40257444977760315},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3251854181289673},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2391790747642517},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.07637524604797363},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.06507942080497742},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006938","descriptor_name":"Hyperlipoproteinemia Type II","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006938","descriptor_name":"Hyperlipoproteinemia Type II","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010956","descriptor_name":"Plasmapheresis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.2169/naika.75.341","doi":"https://doi.org/10.2169/naika.75.341","is_oa":true,"landing_page_url":"https://doi.org/10.2169/naika.75.341","pdf_url":"https://www.jstage.jst.go.jp/article/naika1913/75/3/75_3_341/_pdf","source":{"id":"https://openalex.org/S4210221755","display_name":"Nihon Naika Gakkai Zasshi","issn_l":"0021-5384","issn":["0021-5384","1883-2083"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Naika Gakkai Zasshi","raw_type":"journal-article"},{"id":"pmid:3746063","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3746063","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.2169/naika.75.341","doi":"https://doi.org/10.2169/naika.75.341","is_oa":true,"landing_page_url":"https://doi.org/10.2169/naika.75.341","pdf_url":"https://www.jstage.jst.go.jp/article/naika1913/75/3/75_3_341/_pdf","source":{"id":"https://openalex.org/S4210221755","display_name":"Nihon Naika Gakkai Zasshi","issn_l":"0021-5384","issn":["0021-5384","1883-2083"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Naika Gakkai Zasshi","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2340366235.pdf","grobid_xml":"https://content.openalex.org/works/W2340366235.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2417134791","https://openalex.org/W2076980287","https://openalex.org/W2394913637","https://openalex.org/W2337196525","https://openalex.org/W2078379840","https://openalex.org/W7001940985","https://openalex.org/W2425302156","https://openalex.org/W7009928263","https://openalex.org/W1996277023","https://openalex.org/W2463388792"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}