{"id":"https://openalex.org/W2338539712","doi":"https://doi.org/10.1093/jnci/59.5.1397","title":"Mammographic Parenchymal Pattern and the Risk of Breast Cancer 2","display_name":"Mammographic Parenchymal Pattern and the Risk of Breast Cancer 2","publication_year":1977,"publication_date":"1977-11-01","ids":{"openalex":"https://openalex.org/W2338539712","doi":"https://doi.org/10.1093/jnci/59.5.1397","mag":"2338539712","pmid":"https://pubmed.ncbi.nlm.nih.gov/909098"},"language":"en","primary_location":{"id":"doi:10.1093/jnci/59.5.1397","doi":"https://doi.org/10.1093/jnci/59.5.1397","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jnci/59.5.1397","pdf_url":null,"source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101418515","display_name":"Elaine Wilkinson","orcid":"https://orcid.org/0000-0002-2505-7594","observed_orcids":["https://orcid.org/0000-0002-2505-7594"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. Wilkinson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032602154","display_name":"C. Clopton","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Clopton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"J. Gordonson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Gordonson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057187495","display_name":"R. Green","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Green","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049017228","display_name":"Alexandra Hill","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Hill","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5066996389","display_name":"Malcolm C. Pike","orcid":"https://orcid.org/0000-0003-4891-1199","observed_orcids":["https://orcid.org/0000-0003-4891-1199"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. C. Pike","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5436,"currency":"USD","value_usd":5436},"apc_paid":null,"fwci":7.8919,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.9751088,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"59","issue":"5","first_page":"1397","last_page":"1400"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11361","display_name":"Digital Radiography and Breast Imaging","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11361","display_name":"Digital Radiography and Breast Imaging","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mammographic-parenchymal-patterns","display_name":"mammographic parenchymal patterns","score":0.9710000157356262},{"id":"https://openalex.org/keywords/breast-cancer-risk","display_name":"breast cancer risk","score":0.9739999771118164},{"id":"https://openalex.org/keywords/xeromammography","display_name":"xeromammography","score":0.7390000224113464},{"id":"https://openalex.org/keywords/breast-cancer-risk-factors","display_name":"breast cancer risk factors","score":0.5379999876022339},{"id":"https://openalex.org/keywords/breast-ducts","display_name":"breast ducts","score":0.5389999747276306},{"id":"https://openalex.org/keywords/breast-dysplasia","display_name":"breast dysplasia","score":0.7559999823570251},{"id":"https://openalex.org/keywords/wolfe-classification","display_name":"Wolfe classification","score":0.5260000228881836},{"id":"https://openalex.org/keywords/breast-cancer-detection-demonstration-project","display_name":"Breast Cancer Detection Demonstration Project","score":0.7950000166893005},{"id":"https://openalex.org/keywords/parity","display_name":"parity","score":0.531000018119812},{"id":"https://openalex.org/keywords/age-at-menopause","display_name":"age at menopause","score":0.578000009059906},{"id":"https://openalex.org/keywords/family-history-of-breast-cancer","display_name":"family history of breast cancer","score":0.9599999785423279}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.8394151926040649},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7439515590667725},{"id":"https://openalex.org/C2780639617","wikidata":"https://www.wikidata.org/wiki/Q6516972","display_name":"Quadrant (abdomen)","level":2,"score":0.576024055480957},{"id":"https://openalex.org/C2776601875","wikidata":"https://www.wikidata.org/wiki/Q1833750","display_name":"Risk factors for breast cancer","level":4,"score":0.5624058246612549},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.5409847497940063},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.523703932762146},{"id":"https://openalex.org/C2775894508","wikidata":"https://www.wikidata.org/wiki/Q1128996","display_name":"Dysplasia","level":2,"score":0.48490649461746216},{"id":"https://openalex.org/C196822366","wikidata":"https://www.wikidata.org/wiki/Q270524","display_name":"Parenchyma","level":2,"score":0.4812304973602295},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.45894184708595276},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.44460198283195496},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.43922674655914307},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.3650903105735779},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32161831855773926},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1776672899723053}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011230","descriptor_name":"Precancerous Conditions","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011230","descriptor_name":"Precancerous Conditions","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011230","descriptor_name":"Precancerous Conditions","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014984","descriptor_name":"Xeromammography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014984","descriptor_name":"Xeromammography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014984","descriptor_name":"Xeromammography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/jnci/59.5.1397","doi":"https://doi.org/10.1093/jnci/59.5.1397","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jnci/59.5.1397","pdf_url":null,"source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},{"id":"pmid:909098","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/909098","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the National Cancer Institute","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.8500000238418579,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1977358296","https://openalex.org/W7100326564","https://openalex.org/W2339292134","https://openalex.org/W2472995055","https://openalex.org/W1929963980","https://openalex.org/W1851887764","https://openalex.org/W4237466525","https://openalex.org/W1985386315","https://openalex.org/W1999329030","https://openalex.org/W2055946303"],"abstract_inverted_index":{"Xeromammograms":[0],"of":[1,22,26,32,44,56,75,82,109,120,137,212,227,231,240],"women":[2,208],"with":[3,30,97,158,252],"breast":[4,45,154,157,164,186,241],"cancer":[5,159,165,187],"detected":[6],"at":[7,17,78,229,235],"the":[8,18,37,53,70,92,101,107,110,135,138,153,156,163,170,174,185,223,253,257],"National":[9],"Cancer":[10,13],"Institute's":[11],"Breast":[12],"Detection":[14],"Demonstration":[15],"Project":[16],"Los":[19],"Angeles":[20],"County/University":[21],"Southern":[23],"California":[24],"School":[25],"Medicine":[27],"were":[28,49,87,160,179,190,250,259],"compared":[29],"those":[31,168],"control":[33,244],"women,":[34,245],"chosen":[35],"from":[36,152,169],"Project's":[38],"files,":[39],"who":[40],"showed":[41],"no":[42,85],"evidence":[43],"cancer.":[46,242],"The":[47,202],"mammograms":[48,151],"categorized":[50],"according":[51],"to":[52,105,183],"classification":[54],"scheme":[55,203],"J.":[57],"N.":[58],"Wolfe":[59],"into":[60,123],"four":[61],"groups":[62],"(N1,":[63],"P1,":[64,91],"P2,":[65,128],"and":[66,84,167,195,197,221,237],"DY).ln":[67],"group":[68,90,127,141],"N1,":[69,184],"parenchyma":[71,93],"was":[72,94,145,216],"composed":[73],"primarily":[74],"fat":[76,96],"with,":[77],"most,":[79],"small":[80],"amounts":[81],"\u201cdysplasia,\u201d":[83],"ducts":[86,99,121,130],"visible.":[88],"In":[89,126,140,181,243],"chiefly":[95],"prominent":[98,129],"in":[100,173,207],"anterior":[102],"portion":[103],"up":[104],"one-fourth":[106,134],"volume":[108,136],"breast,":[111],"but":[112,256],"it":[113],"also":[114],"could":[115],"be":[116],"a":[117,124,217],"thin":[118],"band":[119],"extending":[122],"quadrant.":[125],"occupied":[131],"more":[132],"than":[133],"breast.":[139],"DY,":[142],"severe":[143],"\"dysplasia\"":[144],"found.":[146],"To":[147],"avoid":[148],"bias,":[149],"only":[150],"opposite":[155],"used":[161],"for":[162,192,199],"patients,":[166],"corresponding":[171],"breasts":[172],"patient's":[175],"2":[176],"matched":[177],"controls":[178],"utilized.":[180],"comparison":[182],"risk":[188,218,225,248],"ratios":[189],"2.1":[191],"both":[193],"P1":[194],"P2":[196],"5.8":[198],"DY":[200],"(P<0.01).":[201],"appeared":[204],"particularly":[205],"useful":[206],"under":[209],"55":[210],"years":[211],"age.":[213],"Mammographic":[214],"pattern":[215,255],"factor":[219],"over":[220],"above":[222],"known":[224,247],"factors":[226,249],"age":[228,234],"birth":[230],"first":[232],"child,":[233],"menopause,":[236],"family":[238],"history":[239],"these":[246],"correlated":[251],"parenchymal":[254],"results":[258],"not":[260],"statistically":[261],"significant.":[262]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}