{"id":"https://openalex.org/W2337765199","doi":"https://doi.org/10.1056/nejm195911192612102","title":"Treatment of Kaposi's Sarcoma of the Lower Extremity by Extracorporeal Perfusion with Chemotherapeutic Agents","display_name":"Treatment of Kaposi's Sarcoma of the Lower Extremity by Extracorporeal Perfusion with Chemotherapeutic Agents","publication_year":1959,"publication_date":"1959-11-19","ids":{"openalex":"https://openalex.org/W2337765199","doi":"https://doi.org/10.1056/nejm195911192612102","mag":"2337765199","pmid":"https://pubmed.ncbi.nlm.nih.gov/14423490"},"language":"en","primary_location":{"id":"doi:10.1056/nejm195911192612102","doi":"https://doi.org/10.1056/nejm195911192612102","is_oa":false,"landing_page_url":"https://doi.org/10.1056/nejm195911192612102","pdf_url":null,"source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038938677","display_name":"Anthony P. Monaco","orcid":"https://orcid.org/0000-0001-7480-3197","observed_orcids":["https://orcid.org/0000-0001-7480-3197"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony P. Monaco","raw_affiliation_strings":["Resident in surgery, Massachusetts General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Resident in surgery, Massachusetts General Hospital","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110037066","display_name":"William Gerald Austen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Gerald Austen","raw_affiliation_strings":["Resident in surgery, Massachusetts General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Resident in surgery, Massachusetts General Hospital","institution_ids":["https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210087915"],"apc_list":null,"apc_paid":null,"fwci":7.6729,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.97231575,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"261","issue":"21","first_page":"1045","last_page":"1052"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kaposi-sarcoma","display_name":"Kaposi's sarcoma","score":1.0},{"id":"https://openalex.org/keywords/lower-limb","display_name":"lower extremity","score":0.9359999895095825},{"id":"https://openalex.org/keywords/extracorporeal-perfusion","display_name":"extracorporeal perfusion","score":0.9829999804496765},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.7919999957084656}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.944424033164978},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.8001754283905029},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6512134075164795},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5920637249946594},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5851465463638306},{"id":"https://openalex.org/C2779236070","wikidata":"https://www.wikidata.org/wiki/Q725345","display_name":"Kaposi's sarcoma","level":4,"score":0.578472375869751},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.534444272518158},{"id":"https://openalex.org/C2779915274","wikidata":"https://www.wikidata.org/wiki/Q1115882","display_name":"Extracorporeal","level":2,"score":0.47200891375541687},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4449578523635864},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.38496971130371094},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3050200939178467},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.28180980682373047},{"id":"https://openalex.org/C3018958071","wikidata":"https://www.wikidata.org/wiki/Q149348","display_name":"Human herpesvirus","level":3,"score":0.09409508109092712},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007866","descriptor_name":"Leg","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012509","descriptor_name":"Sarcoma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012514","descriptor_name":"Sarcoma, Kaposi","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D035002","descriptor_name":"Lower Extremity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1056/nejm195911192612102","doi":"https://doi.org/10.1056/nejm195911192612102","is_oa":false,"landing_page_url":"https://doi.org/10.1056/nejm195911192612102","pdf_url":null,"source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:14423490","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14423490","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The New England journal of medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1871703208","https://openalex.org/W1968740973","https://openalex.org/W1971875233","https://openalex.org/W2006111043","https://openalex.org/W2009963656","https://openalex.org/W2026187695","https://openalex.org/W2033005592","https://openalex.org/W2035243396","https://openalex.org/W2045565618","https://openalex.org/W2045964091","https://openalex.org/W2059124048","https://openalex.org/W2078877024","https://openalex.org/W2086260870","https://openalex.org/W2087306750","https://openalex.org/W2092951076","https://openalex.org/W2099225947","https://openalex.org/W2106854568","https://openalex.org/W2460754965"],"related_works":["https://openalex.org/W2091197267","https://openalex.org/W7217438638","https://openalex.org/W4252899159","https://openalex.org/W2077847943","https://openalex.org/W4251276807","https://openalex.org/W145580854","https://openalex.org/W1794290254","https://openalex.org/W2054364598","https://openalex.org/W2406618323","https://openalex.org/W2469295569"],"abstract_inverted_index":{"KAPOSI'S":[0],"sarcoma,":[1],"or":[2],"\"idiopathic":[3],"multiple":[4],"hemorrhagic":[5],"sarcoma,\"":[6],"was":[7],"first":[8],"described":[9],"as":[10],"a":[11,25,35,78],"clinical":[12,29],"entity":[13],"by":[14],"Kaposi":[15],"in":[16,50,67,73,82],"1872.":[17],"The":[18],"disease":[19,64],"is":[20,48,65,71,87],"progressive,":[21],"and":[22,30,42,94,96],"it":[23,97],"exhibits":[24],"wide":[26],"range":[27],"of":[28,45,101],"histologic":[31],"variations.":[32],"It":[33],"has":[34],"singular":[36],"propensity":[37],"for":[38],"the":[39,51,57,63,92,99],"male":[40],"Jewish":[41],"Italian":[43],"population":[44],"Eastern":[46],"Europe,":[47],"common":[49],"African":[52],"Negro,":[53],"but":[54],"rarely":[55],"affects":[56],"female.1":[58],"2":[59],"3":[60],"4":[61],"Although":[62],"reported":[66],"adolescence,1":[68],"its":[69],"onset":[70],"usually":[72],"persons":[74],"over":[75],"forty,":[76],"with":[77],"progressively":[79],"increasing":[80],"incidence":[81],"succeeding":[83],"decades.The":[84],"initial":[85],"lesion":[86],"most":[88],"often":[89],"found":[90],"on":[91],"hands":[93],"feet,":[95],"takes":[98],"form":[100],".":[102,103,104]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}