{"id":"https://openalex.org/W2336441906","doi":"https://doi.org/10.17116/terarkh201587640-44","title":"Impact of interleukin-10 and interleukin-28 gene polymorphisms on the development and course of lupus nephritis","display_name":"Impact of interleukin-10 and interleukin-28 gene polymorphisms on the development and course of lupus nephritis","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2336441906","doi":"https://doi.org/10.17116/terarkh201587640-44","mag":"2336441906","pmid":"https://pubmed.ncbi.nlm.nih.gov/26281194"},"language":"ru","primary_location":{"id":"doi:10.17116/terarkh201587640-44","doi":"https://doi.org/10.17116/terarkh201587640-44","is_oa":true,"landing_page_url":"https://doi.org/10.17116/terarkh201587640-44","pdf_url":null,"source":{"id":"https://openalex.org/S27897580","display_name":"Terapevticheskii arkhiv","issn_l":"0040-3660","issn":["0040-3660","2309-5342"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","jufo-1","medline","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4320800547","host_organization_name":"Consilium Medicum","host_organization_lineage":["https://openalex.org/P4320800547"],"host_organization_lineage_names":["Consilium Medicum"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Terapevticheskii arkhiv","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.17116/terarkh201587640-44","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033846654","display_name":"Tatyana N. Krasnova","orcid":"https://orcid.org/0000-0001-6175-1076","observed_orcids":["https://orcid.org/0000-0001-6175-1076"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"T. N. Krasnova","raw_affiliation_strings":["Department of Internal Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110838310","display_name":"Larisa Mikhailovna Samokhodskaya","orcid":"https://orcid.org/0000-0001-6734-3989","observed_orcids":["https://orcid.org/0000-0001-6734-3989"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"L. M. Samokhodskaya","raw_affiliation_strings":["Laboratory of Gene and Cell Technologies, Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene and Cell Technologies, Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089557973","display_name":"\u041b. \u0412. \u0418\u0432\u0430\u043d\u0438\u0446\u043a\u0438\u0439","orcid":"https://orcid.org/0000-0002-5761-7891","observed_orcids":["https://orcid.org/0000-0002-5761-7891"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"L. V. Ivanitsky","raw_affiliation_strings":["Department of Internal Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041049928","display_name":"A D Korogodina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. D. Korogodina","raw_affiliation_strings":["E.M. Tareev Clinic of Nephrology, Internal and Occupational Diseases, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"E.M. Tareev Clinic of Nephrology, Internal and Occupational Diseases, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia","institution_ids":["https://openalex.org/I17877952","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047484391","display_name":"\u0415. \u041d. \u0411\u043e\u0440\u0438\u0441\u043e\u0432","orcid":"https://orcid.org/0000-0002-2216-0326","observed_orcids":["https://orcid.org/0000-0002-2216-0326"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"E. N. Borisov","raw_affiliation_strings":["Department of Internal Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003669962","display_name":"\u041d\u0438\u043a\u0438\u0444\u043e\u0440\u043e\u0432\u0430 \u041d\u0430\u0434\u0435\u0436\u0434\u0430 \u0412\u0438\u043a\u0442\u043e\u0440\u043e\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0001-8060-109X","observed_orcids":["https://orcid.org/0000-0001-8060-109X"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"N. V. Nikiforova","raw_affiliation_strings":["E.M. Tareev Clinic of Nephrology, Internal and Occupational Diseases, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"E.M. Tareev Clinic of Nephrology, Internal and Occupational Diseases, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia","institution_ids":["https://openalex.org/I17877952","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009125671","display_name":"Pavel I Novikov","orcid":"https://orcid.org/0000-0003-0148-5655","observed_orcids":["https://orcid.org/0000-0003-0148-5655"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"P. I. Novikov","raw_affiliation_strings":["E.M. Tareev Clinic of Nephrology, Internal and Occupational Diseases, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"E.M. Tareev Clinic of Nephrology, Internal and Occupational Diseases, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia","institution_ids":["https://openalex.org/I17877952","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001292864","display_name":"Armais Albertovich Kamalov","orcid":"https://orcid.org/0000-0003-4251-7545","observed_orcids":["https://orcid.org/0000-0003-4251-7545"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. A. Kamalov","raw_affiliation_strings":["Medical Research and Education Center, M.V. Lomonosov Moscow State University, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research and Education Center, M.V. Lomonosov Moscow State University, Moscow, Russia","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103002995","display_name":"Nikolay Alekseevich Mukhin","orcid":"https://orcid.org/0000-0003-0382-6230","observed_orcids":["https://orcid.org/0000-0003-0382-6230"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"N. A. Mukhin","raw_affiliation_strings":["Department of Internal Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia","institution_ids":["https://openalex.org/I19880235"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6922,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.68846879,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"87","issue":"6","first_page":"40","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lupus-nephritis","display_name":"lupus nephritis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9599999785423279},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.9259999990463257},{"id":"https://openalex.org/keywords/il-28","display_name":"IL-28","score":0.9620000123977661},{"id":"https://openalex.org/keywords/rs8099917","display_name":"rs8099917","score":0.8700000047683716},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.7519999742507935},{"id":"https://openalex.org/keywords/renal-survival","display_name":"renal survival","score":0.9190000295639038},{"id":"https://openalex.org/keywords/proteinuria","display_name":"proteinuria","score":0.9750000238418579},{"id":"https://openalex.org/keywords/nephritic-syndrome","display_name":"nephritic syndrome","score":0.925000011920929},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.8600000143051147}],"concepts":[{"id":"https://openalex.org/C2779912601","wikidata":"https://www.wikidata.org/wiki/Q1621830","display_name":"Lupus nephritis","level":3,"score":0.8391578793525696},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.8211055994033813},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.6617834568023682},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6617612838745117},{"id":"https://openalex.org/C2779147130","wikidata":"https://www.wikidata.org/wiki/Q2074424","display_name":"Nephritic syndrome","level":4,"score":0.6090598702430725},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5184656977653503},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4278518855571747},{"id":"https://openalex.org/C2779561371","wikidata":"https://www.wikidata.org/wiki/Q570197","display_name":"Proteinuria","level":3,"score":0.3982844054698944},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3278067708015442},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2746094763278961},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23769810795783997},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2060278058052063},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.17032140493392944},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.058987051248550415}],"mesh":[{"descriptor_ui":"D000095022","descriptor_name":"Interferon Lambda","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007378","descriptor_name":"Interleukins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007378","descriptor_name":"Interleukins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008181","descriptor_name":"Lupus Nephritis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008181","descriptor_name":"Lupus Nephritis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.17116/terarkh201587640-44","doi":"https://doi.org/10.17116/terarkh201587640-44","is_oa":true,"landing_page_url":"https://doi.org/10.17116/terarkh201587640-44","pdf_url":null,"source":{"id":"https://openalex.org/S27897580","display_name":"Terapevticheskii arkhiv","issn_l":"0040-3660","issn":["0040-3660","2309-5342"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","jufo-1","medline","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4320800547","host_organization_name":"Consilium Medicum","host_organization_lineage":["https://openalex.org/P4320800547"],"host_organization_lineage_names":["Consilium Medicum"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Terapevticheskii arkhiv","raw_type":"journal-article"},{"id":"pmid:26281194","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26281194","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Terapevticheskii arkhiv","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:ff165c84c4ec4b32932996245caed5e5","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ff165c84c4ec4b32932996245caed5e5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0422\u0435\u0440\u0430\u043f\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0430\u0440\u0445\u0438\u0432, Vol 87, Iss 6, Pp 40-44 (2015)","raw_type":"article"},{"id":"mag:2969351807","doi":null,"is_oa":false,"landing_page_url":"https://cyberleninka.ru/article/n/vliyanie-polimorfizmov-genov-interleykina-10-i-interleykina-28-na-razvitie-i-techenie-volchanochnogo-nefrita","pdf_url":null,"source":{"id":"https://openalex.org/S4306401404","display_name":"CyberLeninK (CyberLeninka)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u0422\u0435\u0440\u0430\u043f\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0430\u0440\u0445\u0438\u0432","raw_type":null}],"best_oa_location":{"id":"doi:10.17116/terarkh201587640-44","doi":"https://doi.org/10.17116/terarkh201587640-44","is_oa":true,"landing_page_url":"https://doi.org/10.17116/terarkh201587640-44","pdf_url":null,"source":{"id":"https://openalex.org/S27897580","display_name":"Terapevticheskii arkhiv","issn_l":"0040-3660","issn":["0040-3660","2309-5342"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","jufo-1","medline","norway-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4320800547","host_organization_name":"Consilium Medicum","host_organization_lineage":["https://openalex.org/P4320800547"],"host_organization_lineage_names":["Consilium Medicum"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Terapevticheskii arkhiv","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W202035856","https://openalex.org/W205803622","https://openalex.org/W1961276029","https://openalex.org/W1966755507","https://openalex.org/W1985776841","https://openalex.org/W2017870772","https://openalex.org/W2049298370","https://openalex.org/W2068817704","https://openalex.org/W2132743350"],"related_works":["https://openalex.org/W2388622194","https://openalex.org/W2316915151","https://openalex.org/W2337231636","https://openalex.org/W2415772833","https://openalex.org/W2186263798","https://openalex.org/W2464462517","https://openalex.org/W2154190033","https://openalex.org/W4386434127","https://openalex.org/W2052322134","https://openalex.org/W2016937109"],"abstract_inverted_index":{"AIM:":[0],"To":[1],"assess":[2],"the":[3,6,17,51,64,76,81,98,118,127,142,154,165,178,198,204,212,222,225,228,244,251,255],"relationship":[4],"of":[5,8,19,50,54,75,97,117,141,156,168,200,206,214,216,227,243,254],"carriage":[7,226],"IL-10-1080":[9],"G/A":[10,145],"and":[11,73,79,114,132,192,211,218,241],"IL-28":[12,100,193,246],"rs8099917":[13,121],"C/T":[14],"polymorphisms":[15,40],"to":[16,149,183,239,250],"course":[18,253],"lupus":[20,30,209],"nephritis":[21],"(LN).":[22],"SUBJECTS":[23],"AND":[24],"METHODS:":[25],"Ninety-nine":[26],"patients":[27,77,105,125],"with":[28,35,78,197,235],"systemic":[29],"erythematosus":[31],"(SLE),":[32],"including":[33],"68":[34],"LN,":[36],"were":[37,41,71,147,195],"examined.":[38],"Gene":[39],"analyzed":[42],"using":[43],"standard":[44],"molecular":[45],"genetic":[46],"techniques.":[47],"The":[48,89,189],"frequency":[49],"clinical":[52],"manifestations":[53],"LN":[55,138,223],"was":[56,61,92],"analyzed;":[57],"renal":[58,208],"survival":[59],"(RS)":[60],"estimated":[62],"by":[63],"Kaplan-Meier":[65],"method.":[66],"RESULTS:":[67],"Ten-year":[68],"RS":[69,91],"rates":[70],"80":[72],"86%":[74],"without":[80,106,126,164],"mutant":[82,99,108,119,129,143,166,179,190,229,245],"IL-10":[83,191,230],"allele,":[84,146],"respectively":[85],"(p":[86,186],"=":[87,112,136,175,187],"0.78).":[88],"10-year":[90],"lower":[93],"(75%)":[94],"in":[95,104,115,124,153],"carriers":[96,140,181],"rsl2979860":[101],"allele":[102,109,122,130,167,180,231,247],"than":[103,123,162],"this":[107,169],"(83%;":[110],"p":[111,135,174],"0.049)":[113],"those":[116,163],"IL28":[120],"above":[128],"(67":[131],"88%,":[133],"respectively;":[134],"0.047).":[137],"patients,":[139,224],"IL-10-1028":[144],"observed":[148],"have":[150],"higher-grade":[151],"proteinuria":[152],"presence":[155],"nephritic":[157],"syndrome":[158],"(mean":[159,171],"6.1":[160],"g/l)":[161],"gene":[170],"2.9":[172],"g/l;":[173],"0.034).":[176],"However,":[177],"responded":[182],"treatment":[184,240],"better":[185,237],"0.050).":[188],"alleles":[194],"unassociated":[196],"development":[199],"rapidly":[201],"progressive":[202],"nephritis,":[203],"activity":[205],"a":[207,236],"process,":[210],"rate":[213],"onset":[215],"SLE":[217],"LN.":[219],"CONCLUSION:":[220],"In":[221],"A":[232],"is":[233,248],"associated":[234],"response":[238],"that":[242],"linked":[249],"severe":[252],"disease.":[256]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}