{"id":"https://openalex.org/W2335147237","doi":"https://doi.org/10.1038/ng.3535","title":"Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults","display_name":"Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults","publication_year":2016,"publication_date":"2016-03-28","ids":{"openalex":"https://openalex.org/W2335147237","doi":"https://doi.org/10.1038/ng.3535","mag":"2335147237","pmid":"https://pubmed.ncbi.nlm.nih.gov/27019113"},"language":"en","primary_location":{"id":"doi:10.1038/ng.3535","doi":"https://doi.org/10.1038/ng.3535","is_oa":false,"landing_page_url":"https://doi.org/10.1038/ng.3535","pdf_url":null,"source":{"id":"https://openalex.org/S137905309","display_name":"Nature Genetics","issn_l":"1061-4036","issn":["1061-4036","1546-1718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Genetics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057556649","display_name":"Takahiko Yasuda","orcid":"https://orcid.org/0000-0002-4686-0976","observed_orcids":["https://orcid.org/0000-0002-4686-0976"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takahiko Yasuda","raw_affiliation_strings":["Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018873082","display_name":"Shinobu Tsuzuki","orcid":"https://orcid.org/0000-0002-3209-3550","observed_orcids":["https://orcid.org/0000-0002-3209-3550"]},"institutions":[{"id":"https://openalex.org/I4405286296","display_name":"Aichi Cancer Center Research Institute","ror":"https://ror.org/01rsenb03","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210133851","https://openalex.org/I4405286296"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinobu Tsuzuki","raw_affiliation_strings":["Division of Molecular Medicine, Aichi Cancer Center Research Institute, Aichi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular Medicine, Aichi Cancer Center Research Institute, Aichi, Japan","institution_ids":["https://openalex.org/I4405286296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032033606","display_name":"Masahito Kawazu","orcid":"https://orcid.org/0000-0003-4146-3629","observed_orcids":["https://orcid.org/0000-0003-4146-3629"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahito Kawazu","raw_affiliation_strings":["Department of Medical Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042332379","display_name":"Fumihiko Hayakawa","orcid":"https://orcid.org/0000-0002-6067-6382","observed_orcids":["https://orcid.org/0000-0002-6067-6382"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Fumihiko Hayakawa","raw_affiliation_strings":["Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090361788","display_name":"Shinya Kojima","orcid":"https://orcid.org/0009-0002-3223-2634","observed_orcids":["https://orcid.org/0009-0002-3223-2634"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinya Kojima","raw_affiliation_strings":["Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074950427","display_name":"Toshihide Ueno","orcid":"https://orcid.org/0000-0002-7408-7298","observed_orcids":["https://orcid.org/0000-0002-7408-7298"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshihide Ueno","raw_affiliation_strings":["Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103216210","display_name":"Naoto Imoto","orcid":"https://orcid.org/0000-0003-0567-8761","observed_orcids":["https://orcid.org/0000-0003-0567-8761","https://orcid.org/0000-0002-6293-1914"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoto Imoto","raw_affiliation_strings":["Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055160098","display_name":"Shinji Kohsaka","orcid":"https://orcid.org/0000-0001-8651-6136","observed_orcids":["https://orcid.org/0000-0001-8651-6136"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinji Kohsaka","raw_affiliation_strings":["Department of Medical Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046301056","display_name":"Akiko Kunita","orcid":"https://orcid.org/0009-0008-9989-8258","observed_orcids":["https://orcid.org/0009-0008-9989-8258"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akiko Kunita","raw_affiliation_strings":["Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101056725","display_name":"Koichiro Doi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koichiro Doi","raw_affiliation_strings":["Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015344411","display_name":"Toru Sakura","orcid":"https://orcid.org/0000-0002-6280-5416","observed_orcids":["https://orcid.org/0000-0002-6280-5416"]},"institutions":[{"id":"https://openalex.org/I4210133122","display_name":"Gunma Saiseikai Maebashi Hospital","ror":"https://ror.org/033js5093","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210133122"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toru Sakura","raw_affiliation_strings":["Leukemia Research Center, Saiseikai Maebashi Hospital, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leukemia Research Center, Saiseikai Maebashi Hospital, Gunma, Japan","institution_ids":["https://openalex.org/I4210133122"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085637628","display_name":"Toshiaki Yujiri","orcid":"https://orcid.org/0000-0001-6838-3456","observed_orcids":["https://orcid.org/0000-0001-6838-3456"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshiaki Yujiri","raw_affiliation_strings":["Third Department of Internal Medicine, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Department of Internal Medicine, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085000681","display_name":"Eisei Kondo","orcid":"https://orcid.org/0000-0003-0995-9405","observed_orcids":["https://orcid.org/0000-0003-0995-9405"]},"institutions":[{"id":"https://openalex.org/I163770644","display_name":"Okayama University","ror":"https://ror.org/02pc6pc55","country_code":"JP","type":"education","lineage":["https://openalex.org/I163770644"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eisei Kondo","raw_affiliation_strings":["Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan","institution_ids":["https://openalex.org/I163770644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082863122","display_name":"Katsumichi Fujimaki","orcid":"https://orcid.org/0000-0002-9996-6459","observed_orcids":["https://orcid.org/0000-0002-9996-6459"]},"institutions":[{"id":"https://openalex.org/I2799590887","display_name":"Fujisawa City Hospital","ror":"https://ror.org/04dd5bw95","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799590887"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsumichi Fujimaki","raw_affiliation_strings":["Department of Hematology, Fujisawa City Hospital, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Fujisawa City Hospital, Kanagawa, Japan","institution_ids":["https://openalex.org/I2799590887"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103131907","display_name":"Yasunori Ueda","orcid":"https://orcid.org/0000-0002-4487-5808","observed_orcids":["https://orcid.org/0000-0002-4487-5808"]},"institutions":[{"id":"https://openalex.org/I4210089671","display_name":"Kurashiki Central Hospital","ror":"https://ror.org/00947s692","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210089671"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasunori Ueda","raw_affiliation_strings":["Department of Hematology/Oncology, Kurashiki Central Hospital, Okayama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology/Oncology, Kurashiki Central Hospital, Okayama, Japan","institution_ids":["https://openalex.org/I4210089671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042894205","display_name":"Yasutaka Aoyama","orcid":"https://orcid.org/0000-0003-4799-5140","observed_orcids":["https://orcid.org/0000-0003-4799-5140"]},"institutions":[{"id":"https://openalex.org/I4210164693","display_name":"Fuchu Hospital","ror":"https://ror.org/05q3m8e94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210164693"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasutaka Aoyama","raw_affiliation_strings":["Department of Internal Medicine, Seichoukai Fuchu Hospital, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Seichoukai Fuchu Hospital, Osaka, Japan","institution_ids":["https://openalex.org/I4210164693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013146671","display_name":"Shigeki Ohtake","orcid":"https://orcid.org/0000-0003-0112-6564","observed_orcids":["https://orcid.org/0000-0003-0112-6564"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeki Ohtake","raw_affiliation_strings":["Department of Clinical Laboratory Science, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Laboratory Science, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078968582","display_name":"Junko Takita","orcid":"https://orcid.org/0000-0002-2452-6520","observed_orcids":["https://orcid.org/0000-0002-2452-6520"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junko Takita","raw_affiliation_strings":["Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027103782","display_name":"Eirin Sai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eirin Sai","raw_affiliation_strings":["Department of Medical Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113628512","display_name":"Masafumi Taniwaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40677808","display_name":"Kyoto Prefectural University of Medicine","ror":"https://ror.org/028vxwa22","country_code":"JP","type":"education","lineage":["https://openalex.org/I40677808","https://openalex.org/I4405285717"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masafumi Taniwaki","raw_affiliation_strings":["Division of Hematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I40677808"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085709435","display_name":"Mineo Kurokawa","orcid":"https://orcid.org/0000-0002-4034-2422","observed_orcids":["https://orcid.org/0000-0002-4034-2422"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mineo Kurokawa","raw_affiliation_strings":["Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049124202","display_name":"Shinichi Morishita","orcid":"https://orcid.org/0000-0002-6201-8885","observed_orcids":["https://orcid.org/0000-0002-6201-8885"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinichi Morishita","raw_affiliation_strings":["Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005708651","display_name":"Masashi Fukayama","orcid":"https://orcid.org/0000-0002-0460-064X","observed_orcids":["https://orcid.org/0000-0002-0460-064X"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masashi Fukayama","raw_affiliation_strings":["Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002642944","display_name":"Hitoshi Kiyoi","orcid":"https://orcid.org/0000-0001-6382-9498","observed_orcids":["https://orcid.org/0000-0001-6382-9498"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hitoshi Kiyoi","raw_affiliation_strings":["Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070702322","display_name":"Yasushi Miyazaki","orcid":"https://orcid.org/0000-0003-3683-7147","observed_orcids":["https://orcid.org/0000-0003-3683-7147"]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]},{"id":"https://openalex.org/I4405285995","display_name":"Atomic Bomb Disease Institute, Nagasaki University","ror":"https://ror.org/00wc6zv93","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43777268","https://openalex.org/I4405285995"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasushi Miyazaki","raw_affiliation_strings":["Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan","institution_ids":["https://openalex.org/I43777268","https://openalex.org/I4405285995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113454854","display_name":"Tomoki Naoe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137409","display_name":"National Hospital Organization","ror":"https://ror.org/03ntccx93","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210137409"]},{"id":"https://openalex.org/I4210152596","display_name":"Nagoya Medical Center","ror":"https://ror.org/04ftw3n55","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210152596"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoki Naoe","raw_affiliation_strings":["National Hospital Organization Nagoya Medical Center, Aichi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Hospital Organization Nagoya Medical Center, Aichi, Japan","institution_ids":["https://openalex.org/I4210137409","https://openalex.org/I4210152596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090560513","display_name":"Hiroyuki Mano","orcid":"https://orcid.org/0000-0003-4645-0181","observed_orcids":["https://orcid.org/0000-0003-4645-0181"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Hiroyuki Mano","raw_affiliation_strings":["Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5090560513"],"corresponding_institution_ids":["https://openalex.org/I74801974"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":19.1129,"has_fulltext":false,"cited_by_count":275,"citation_normalized_percentile":{"value":0.9960241,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"48","issue":"5","first_page":"569","last_page":"574"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dux4","display_name":"DUX4","score":0.9110000133514404},{"id":"https://openalex.org/keywords/b-cell-acute-lymphoblastic-leukemia","display_name":"B-cell acute lymphoblastic leukemia","score":0.9710000157356262},{"id":"https://openalex.org/keywords/adolescent-and-young-adult-leukemia","display_name":"adolescent and young adult leukemia","score":0.9710000157356262},{"id":"https://openalex.org/keywords/philadelphia-chromosome-negative-leukemia","display_name":"Philadelphia chromosome-negative leukemia","score":0.8679999709129333},{"id":"https://openalex.org/keywords/d4z4-repeat","display_name":"D4Z4 repeat","score":0.7979999780654907},{"id":"https://openalex.org/keywords/oncogenic-drivers","display_name":"oncogenic drivers","score":0.6549999713897705},{"id":"https://openalex.org/keywords/pro-b-cells","display_name":"pro-B cells","score":0.8130000233650208}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.784050464630127},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5152173638343811},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.514782190322876},{"id":"https://openalex.org/C2909962599","wikidata":"https://www.wikidata.org/wiki/Q180664","display_name":"Lymphoblastic Leukemia","level":3,"score":0.48736101388931274},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.45133620500564575},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4304687976837158},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.40542805194854736},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34203779697418213}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007143","descriptor_name":"Immunoglobulin Heavy Chains","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015514","descriptor_name":"Oncogene Proteins, Fusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015534","descriptor_name":"Trans-Activators","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018398","descriptor_name":"Homeodomain Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D041681","descriptor_name":"NIH 3T3 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050939","descriptor_name":"Gene Fusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054198","descriptor_name":"Precursor Cell Lymphoblastic Leukemia-Lymphoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064326","descriptor_name":"MEF2 Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/ng.3535","doi":"https://doi.org/10.1038/ng.3535","is_oa":false,"landing_page_url":"https://doi.org/10.1038/ng.3535","pdf_url":null,"source":{"id":"https://openalex.org/S137905309","display_name":"Nature Genetics","issn_l":"1061-4036","issn":["1061-4036","1546-1718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Genetics","raw_type":"journal-article"},{"id":"pmid:27019113","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27019113","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature genetics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G4996804531","display_name":"Analysis of the role of circadian clock gene in leukemogenesis","funder_award_id":"26461421","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8136974306","display_name":"Molecular-cytogenetic studies of PVT1 rearrangements in hematological malignancies","funder_award_id":"25461432","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8429999070","display_name":"Molecular cytogenetic studies of MYC and PVT1 rearrangements in refractory and relapsed lymphoma","funder_award_id":"16K09856","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1578918795","https://openalex.org/W1696199194","https://openalex.org/W1791680118","https://openalex.org/W1975589825","https://openalex.org/W1977699908","https://openalex.org/W1978302657","https://openalex.org/W1993652835","https://openalex.org/W1994568187","https://openalex.org/W2010217134","https://openalex.org/W2013560484","https://openalex.org/W2014679135","https://openalex.org/W2017826157","https://openalex.org/W2029623390","https://openalex.org/W2037761873","https://openalex.org/W2044766745","https://openalex.org/W2066054263","https://openalex.org/W2069709802","https://openalex.org/W2081357269","https://openalex.org/W2082127114","https://openalex.org/W2083839606","https://openalex.org/W2093618454","https://openalex.org/W2121242557","https://openalex.org/W2127310310","https://openalex.org/W2136522034","https://openalex.org/W2146022804","https://openalex.org/W2147262371"],"related_works":["https://openalex.org/W2804231890","https://openalex.org/W3013206208","https://openalex.org/W4412732543","https://openalex.org/W2988196700","https://openalex.org/W4400889846","https://openalex.org/W7216770027","https://openalex.org/W3091514640","https://openalex.org/W2951844012","https://openalex.org/W4243494987","https://openalex.org/W4414162495"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":19},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":27},{"year":2023,"cited_by_count":23},{"year":2022,"cited_by_count":34},{"year":2021,"cited_by_count":39},{"year":2020,"cited_by_count":25},{"year":2019,"cited_by_count":23},{"year":2018,"cited_by_count":28},{"year":2017,"cited_by_count":19},{"year":2016,"cited_by_count":13}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}