{"id":"https://openalex.org/W2334557324","doi":"https://doi.org/10.1007/bf02191959","title":"Anxiogenic properties of yohimbine","display_name":"Anxiogenic properties of yohimbine","publication_year":1992,"publication_date":"1992-07-01","ids":{"openalex":"https://openalex.org/W2334557324","doi":"https://doi.org/10.1007/bf02191959","mag":"2334557324","pmid":"https://pubmed.ncbi.nlm.nih.gov/1504111"},"language":"en","primary_location":{"id":"doi:10.1007/bf02191959","doi":"https://doi.org/10.1007/bf02191959","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02191959","pdf_url":null,"source":{"id":"https://openalex.org/S105662685","display_name":"European Archives of Psychiatry and Clinical Neuroscience","issn_l":"0003-9373","issn":["0003-9373","0175-758X","0940-1334","1433-8491"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Archives of Psychiatry and Clinical Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045097461","display_name":"Margot Albus","orcid":"https://orcid.org/0000-0003-1352-2249","observed_orcids":["https://orcid.org/0000-0003-1352-2249"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Margot Albus","raw_affiliation_strings":["Mental State Hospital Haar, Federal Republic of Germany","Mental State Hospital Haar, Vockestr. 72, W-8013, Haar, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mental State Hospital Haar, Federal Republic of Germany","institution_ids":[]},{"raw_affiliation_string":"Mental State Hospital Haar, Vockestr. 72, W-8013, Haar, Federal Republic of Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104061931","display_name":"Theodore P. Zahn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theodore P. Zahn","raw_affiliation_strings":["Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Md"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, Md","institution_ids":["https://openalex.org/I4210158500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110607987","display_name":"Alan F. Breier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alan Breier","raw_affiliation_strings":["Maryland Psychiatric Research Center, Baltimore, Md"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Maryland Psychiatric Research Center, Baltimore, Md","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":null,"fwci":3.8334,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.94588385,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"241","issue":"6","first_page":"345","last_page":"351"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.8842999935150146,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.8842999935150146,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.042399998754262924,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.03869999945163727,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/yohimbine","display_name":"yohimbine","score":1.0},{"id":"https://openalex.org/keywords/anxiogenic-effects","display_name":"anxiogenic effects","score":0.8650000095367432},{"id":"https://openalex.org/keywords/panic-disorder","display_name":"panic disorder","score":0.7760000228881836},{"id":"https://openalex.org/keywords/psychological-stress","display_name":"psychological stress","score":0.8199999928474426},{"id":"https://openalex.org/keywords/mental-arithmetic-task","display_name":"mental arithmetic task","score":0.7360000014305115},{"id":"https://openalex.org/keywords/continuous-performance-test","display_name":"continuous performance test","score":0.9950000047683716},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.7860000133514404},{"id":"https://openalex.org/keywords/electrodermal-activity","display_name":"electrodermal activity","score":0.949999988079071},{"id":"https://openalex.org/keywords/skin-conductance","display_name":"skin conductance","score":0.9269999861717224},{"id":"https://openalex.org/keywords/alprazolam","display_name":"alprazolam","score":0.925000011920929},{"id":"https://openalex.org/keywords/placebo-effect","display_name":"placebo effect","score":0.414000004529953},{"id":"https://openalex.org/keywords/expectancy-effects","display_name":"expectancy effects","score":0.42899999022483826}],"concepts":[{"id":"https://openalex.org/C2777676773","wikidata":"https://www.wikidata.org/wiki/Q412226","display_name":"Yohimbine","level":4,"score":0.8789016008377075},{"id":"https://openalex.org/C205044023","wikidata":"https://www.wikidata.org/wiki/Q4778117","display_name":"Anxiogenic","level":4,"score":0.8645551204681396},{"id":"https://openalex.org/C2777196872","wikidata":"https://www.wikidata.org/wiki/Q319877","display_name":"Alprazolam","level":3,"score":0.6253900527954102},{"id":"https://openalex.org/C2780712732","wikidata":"https://www.wikidata.org/wiki/Q208450","display_name":"Panic","level":3,"score":0.616416871547699},{"id":"https://openalex.org/C2777765862","wikidata":"https://www.wikidata.org/wiki/Q62903","display_name":"Anxiolytic","level":3,"score":0.6155939102172852},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6061093807220459},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.5818739533424377},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5765706300735474},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5557882189750671},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.4627625346183777},{"id":"https://openalex.org/C2777529043","wikidata":"https://www.wikidata.org/wiki/Q741713","display_name":"Panic disorder","level":3,"score":0.45478570461273193},{"id":"https://openalex.org/C2777745069","wikidata":"https://www.wikidata.org/wiki/Q3467463","display_name":"Continuous performance task","level":3,"score":0.4543026387691498},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3093920350074768},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2892742156982422},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20997798442840576},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.08914589881896973},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.07054036855697632},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000223","descriptor_name":"Adaptation, Psychological","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000223","descriptor_name":"Adaptation, Psychological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000379","descriptor_name":"Agoraphobia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D000379","descriptor_name":"Agoraphobia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000379","descriptor_name":"Agoraphobia","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D001143","descriptor_name":"Arousal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001143","descriptor_name":"Arousal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001288","descriptor_name":"Attention","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001288","descriptor_name":"Attention","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005712","descriptor_name":"Galvanic Skin Response","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005712","descriptor_name":"Galvanic Skin Response","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011340","descriptor_name":"Problem Solving","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011340","descriptor_name":"Problem Solving","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011597","descriptor_name":"Psychomotor Performance","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011597","descriptor_name":"Psychomotor Performance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012718","descriptor_name":"Set, Psychology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012931","descriptor_name":"Social Environment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015016","descriptor_name":"Yohimbine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf02191959","doi":"https://doi.org/10.1007/bf02191959","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02191959","pdf_url":null,"source":{"id":"https://openalex.org/S105662685","display_name":"European Archives of Psychiatry and Clinical Neuroscience","issn_l":"0003-9373","issn":["0003-9373","0175-758X","0940-1334","1433-8491"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Archives of Psychiatry and Clinical Neuroscience","raw_type":"journal-article"},{"id":"pmid:1504111","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1504111","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European archives of psychiatry and clinical neuroscience","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W79583294","https://openalex.org/W1506726456","https://openalex.org/W1625910023","https://openalex.org/W1973656555","https://openalex.org/W1976625954","https://openalex.org/W1978755091","https://openalex.org/W1984593818","https://openalex.org/W1993697441","https://openalex.org/W2006684906","https://openalex.org/W2014885375","https://openalex.org/W2016914542","https://openalex.org/W2018091248","https://openalex.org/W2035287899","https://openalex.org/W2044093789","https://openalex.org/W2044678768","https://openalex.org/W2051223781","https://openalex.org/W2063471680","https://openalex.org/W2063545678","https://openalex.org/W2068644401","https://openalex.org/W2071524614","https://openalex.org/W2077378623","https://openalex.org/W2081235841","https://openalex.org/W2090446436","https://openalex.org/W2091923978","https://openalex.org/W2092420072","https://openalex.org/W2093200355","https://openalex.org/W2095348755","https://openalex.org/W2132834629","https://openalex.org/W2145736646","https://openalex.org/W2161782315","https://openalex.org/W2182158096","https://openalex.org/W2312584250","https://openalex.org/W2315713182","https://openalex.org/W2320584505","https://openalex.org/W2339162672","https://openalex.org/W2990442505"],"related_works":["https://openalex.org/W2423018812","https://openalex.org/W1625910023","https://openalex.org/W1994920775","https://openalex.org/W1984593818","https://openalex.org/W2087198931","https://openalex.org/W1978043471","https://openalex.org/W1981112641","https://openalex.org/W2323546369","https://openalex.org/W1999705645","https://openalex.org/W1996114678"],"abstract_inverted_index":null,"counts_by_year":[{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}