{"id":"https://openalex.org/W2333348442","doi":"https://doi.org/10.5603/fhc.a2015.0034","title":"Effects of rosmarinic acid on cognitive and biochemical alterations in ovariectomized rats treated with D-galactose","display_name":"Effects of rosmarinic acid on cognitive and biochemical alterations in ovariectomized rats treated with D-galactose","publication_year":2015,"publication_date":"2015-12-30","ids":{"openalex":"https://openalex.org/W2333348442","doi":"https://doi.org/10.5603/fhc.a2015.0034","mag":"2333348442","pmid":"https://pubmed.ncbi.nlm.nih.gov/26714446"},"language":"en","primary_location":{"id":"doi:10.5603/fhc.a2015.0034","doi":"https://doi.org/10.5603/fhc.a2015.0034","is_oa":true,"landing_page_url":"https://doi.org/10.5603/fhc.a2015.0034","pdf_url":"https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/download/fhc.a2015.0034/30638","source":{"id":"https://openalex.org/S114973247","display_name":"Folia Histochemica et Cytobiologica","issn_l":"0015-5586","issn":["0015-5586","0239-8508","1897-5631"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320293","host_organization_name":"Via Medica","host_organization_lineage":["https://openalex.org/P4310320293"],"host_organization_lineage_names":["Via Medica"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Folia Histochemica et Cytobiologica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/download/fhc.a2015.0034/30638","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008821036","display_name":"Deniz Kantar","orcid":"https://orcid.org/0000-0003-3037-2553","observed_orcids":["https://orcid.org/0000-0003-3037-2553"]},"institutions":[{"id":"https://openalex.org/I197907453","display_name":"Akdeniz University","ror":"https://ror.org/01m59r132","country_code":"TR","type":"education","lineage":["https://openalex.org/I197907453"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Deniz Kantar Gok","raw_affiliation_strings":["Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya, Turkey","institution_ids":["https://openalex.org/I197907453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004837092","display_name":"Nihal \u00d6zt\u00fcrk","orcid":"https://orcid.org/0000-0002-8681-1415","observed_orcids":["https://orcid.org/0000-0002-8681-1415"]},"institutions":[{"id":"https://openalex.org/I197907453","display_name":"Akdeniz University","ror":"https://ror.org/01m59r132","country_code":"TR","type":"education","lineage":["https://openalex.org/I197907453"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Nihal Ozturk","raw_affiliation_strings":["Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya","institution_ids":["https://openalex.org/I197907453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003157679","display_name":"Hakan Er","orcid":"https://orcid.org/0000-0001-7739-4712","observed_orcids":["https://orcid.org/0000-0001-7739-4712"]},"institutions":[{"id":"https://openalex.org/I197907453","display_name":"Akdeniz University","ror":"https://ror.org/01m59r132","country_code":"TR","type":"education","lineage":["https://openalex.org/I197907453"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Hakan Er","raw_affiliation_strings":["Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya","institution_ids":["https://openalex.org/I197907453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068460460","display_name":"Mutay Aslan","orcid":"https://orcid.org/0000-0002-0660-971X","observed_orcids":["https://orcid.org/0000-0002-0660-971X"]},"institutions":[{"id":"https://openalex.org/I197907453","display_name":"Akdeniz University","ror":"https://ror.org/01m59r132","country_code":"TR","type":"education","lineage":["https://openalex.org/I197907453"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mutay Aslan","raw_affiliation_strings":["Department of Biochemistry, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya","institution_ids":["https://openalex.org/I197907453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101925949","display_name":"Necdet Dem\u0131r","orcid":"https://orcid.org/0000-0002-8166-5535","observed_orcids":["https://orcid.org/0000-0002-8166-5535"]},"institutions":[{"id":"https://openalex.org/I197907453","display_name":"Akdeniz University","ror":"https://ror.org/01m59r132","country_code":"TR","type":"education","lineage":["https://openalex.org/I197907453"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Necdet Demir","raw_affiliation_strings":["Department of Histology, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya","institution_ids":["https://openalex.org/I197907453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084668232","display_name":"Narin Derin","orcid":"https://orcid.org/0000-0001-5521-8929","observed_orcids":["https://orcid.org/0000-0001-5521-8929"]},"institutions":[{"id":"https://openalex.org/I197907453","display_name":"Akdeniz University","ror":"https://ror.org/01m59r132","country_code":"TR","type":"education","lineage":["https://openalex.org/I197907453"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Narin Derin","raw_affiliation_strings":["Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya","institution_ids":["https://openalex.org/I197907453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061485726","display_name":"Ay\u015fel A\u011far","orcid":"https://orcid.org/0000-0001-8693-5648","observed_orcids":["https://orcid.org/0000-0001-8693-5648"]},"institutions":[{"id":"https://openalex.org/I197907453","display_name":"Akdeniz University","ror":"https://ror.org/01m59r132","country_code":"TR","type":"education","lineage":["https://openalex.org/I197907453"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Aysel Agar","raw_affiliation_strings":["Department of Physiology, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya","institution_ids":["https://openalex.org/I197907453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109229052","display_name":"Piraye Yarg\u0131\u00e7o\u011flu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197907453","display_name":"Akdeniz University","ror":"https://ror.org/01m59r132","country_code":"TR","type":"education","lineage":["https://openalex.org/I197907453"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Piraye Yargicoglu","raw_affiliation_strings":["Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya. pakkiraz@akdeniz.edu.tr","Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya. pakkiraz@akdeniz.edu.tr","institution_ids":["https://openalex.org/I197907453"]},{"raw_affiliation_string":"Department of Biophysics, Akdeniz University, Faculty of Medicine, Arapsuyu, Antalya","institution_ids":["https://openalex.org/I197907453"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I197907453"],"apc_list":{"value":370,"currency":"EUR","value_usd":399},"apc_paid":{"value":370,"currency":"EUR","value_usd":399},"fwci":1.3748,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.7810083,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"53","issue":"4","first_page":"283","last_page":"293"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.8109999895095825,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.8109999895095825,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13446","display_name":"Antioxidants, Aging, Portulaca oleracea","score":0.1460999995470047,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12891","display_name":"Medicinal Plants and Neuroprotection","score":0.03290000185370445,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rosmarinic-acid","display_name":"rosmarinic acid","score":1.0},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9120000004768372},{"id":"https://openalex.org/keywords/galactose","display_name":"galactose","score":0.9399999976158142},{"id":"https://openalex.org/keywords/ovariectomy","display_name":"ovariectomy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/spatial-memory","display_name":"spatial memory","score":0.7609999775886536},{"id":"https://openalex.org/keywords/locomotor-activity","display_name":"locomotor activity","score":0.9539999961853027},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9670000076293945},{"id":"https://openalex.org/keywords/cyclooxygenase-2","display_name":"cyclooxygenase-2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/prostaglandin-e2","display_name":"prostaglandin E2","score":1.0},{"id":"https://openalex.org/keywords/amyloid-beta-deposition","display_name":"amyloid-beta deposition","score":0.9110000133514404},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.9459999799728394},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.8700000047683716}],"concepts":[{"id":"https://openalex.org/C8264082","wikidata":"https://www.wikidata.org/wiki/Q7113259","display_name":"Ovariectomized rat","level":3,"score":0.8972920179367065},{"id":"https://openalex.org/C2778771215","wikidata":"https://www.wikidata.org/wiki/Q50380051","display_name":"Rosmarinic acid","level":3,"score":0.8137472867965698},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6309329867362976},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.616888701915741},{"id":"https://openalex.org/C2779085643","wikidata":"https://www.wikidata.org/wiki/Q7096029","display_name":"Open field","level":2,"score":0.5016889572143555},{"id":"https://openalex.org/C2777504301","wikidata":"https://www.wikidata.org/wiki/Q418230","display_name":"Thiobarbituric acid","level":4,"score":0.46418872475624084},{"id":"https://openalex.org/C2778173381","wikidata":"https://www.wikidata.org/wiki/Q66589593","display_name":"Galactose","level":2,"score":0.4285022020339966},{"id":"https://openalex.org/C44752575","wikidata":"https://www.wikidata.org/wiki/Q1417562","display_name":"Morris water navigation task","level":3,"score":0.42368435859680176},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4200561046600342},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.40302616357803345},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37004733085632324},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.3645334243774414},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.32764309644699097},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.25235024094581604},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17461207509040833},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.17008069157600403}],"mesh":[{"descriptor_ui":"D000097123","descriptor_name":"Rosmarinic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002934","descriptor_name":"Cinnamates","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D002934","descriptor_name":"Cinnamates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005690","descriptor_name":"Galactose","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005690","descriptor_name":"Galactose","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010052","descriptor_name":"Ovariectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053630","descriptor_name":"Depsides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D053630","descriptor_name":"Depsides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.5603/fhc.a2015.0034","doi":"https://doi.org/10.5603/fhc.a2015.0034","is_oa":true,"landing_page_url":"https://doi.org/10.5603/fhc.a2015.0034","pdf_url":"https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/download/fhc.a2015.0034/30638","source":{"id":"https://openalex.org/S114973247","display_name":"Folia Histochemica et Cytobiologica","issn_l":"0015-5586","issn":["0015-5586","0239-8508","1897-5631"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320293","host_organization_name":"Via Medica","host_organization_lineage":["https://openalex.org/P4310320293"],"host_organization_lineage_names":["Via Medica"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Folia Histochemica et Cytobiologica","raw_type":"journal-article"},{"id":"pmid:26714446","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26714446","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Folia histochemica et cytobiologica","raw_type":"Journal Article"},{"id":"pmh:oai:RePEc:exl:15foli:v:53:y:2015:i:4:p:283-293","doi":null,"is_oa":false,"landing_page_url":"https://www.exeley.com/folia_histochemica_cytobiologica/doi/10.5603/FHC.a2015.0034","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:czasopisma.viamedica.pl:article/42633","doi":null,"is_oa":false,"landing_page_url":"https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/view/fhc.a2015.0034","pdf_url":null,"source":{"id":"https://openalex.org/S4377196119","display_name":"Via Medica Journals","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Folia Histochemica et Cytobiologica; Vol 53, No 4 (2015); 283-293","raw_type":null}],"best_oa_location":{"id":"doi:10.5603/fhc.a2015.0034","doi":"https://doi.org/10.5603/fhc.a2015.0034","is_oa":true,"landing_page_url":"https://doi.org/10.5603/fhc.a2015.0034","pdf_url":"https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/download/fhc.a2015.0034/30638","source":{"id":"https://openalex.org/S114973247","display_name":"Folia Histochemica et Cytobiologica","issn_l":"0015-5586","issn":["0015-5586","0239-8508","1897-5631"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320293","host_organization_name":"Via Medica","host_organization_lineage":["https://openalex.org/P4310320293"],"host_organization_lineage_names":["Via Medica"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Folia Histochemica et Cytobiologica","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.979200005531311,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323377","display_name":"Akdeniz \u00dcniversitesi","ror":"https://ror.org/01m59r132"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2333348442.pdf","grobid_xml":"https://content.openalex.org/works/W2333348442.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W111387551","https://openalex.org/W182481904","https://openalex.org/W1778513781","https://openalex.org/W1936038923","https://openalex.org/W1947395210","https://openalex.org/W1954454186","https://openalex.org/W1965646109","https://openalex.org/W1967073012","https://openalex.org/W1970169800","https://openalex.org/W1971095301","https://openalex.org/W1975556797","https://openalex.org/W1985122965","https://openalex.org/W1986756809","https://openalex.org/W1989954799","https://openalex.org/W1992862180","https://openalex.org/W1996544750","https://openalex.org/W1997343208","https://openalex.org/W2003114613","https://openalex.org/W2007311043","https://openalex.org/W2008321949","https://openalex.org/W2013145243","https://openalex.org/W2013924694","https://openalex.org/W2026524777","https://openalex.org/W2027043109","https://openalex.org/W2031525359","https://openalex.org/W2032339983","https://openalex.org/W2037533858","https://openalex.org/W2040278300","https://openalex.org/W2043348076","https://openalex.org/W2055836920","https://openalex.org/W2063986851","https://openalex.org/W2072245525","https://openalex.org/W2074626057","https://openalex.org/W2075572846","https://openalex.org/W2076246785","https://openalex.org/W2086942905","https://openalex.org/W2087292928","https://openalex.org/W2087568219","https://openalex.org/W2100248591","https://openalex.org/W2119540271","https://openalex.org/W2121806371","https://openalex.org/W2123197349","https://openalex.org/W2128987869","https://openalex.org/W2129111164","https://openalex.org/W2134128650","https://openalex.org/W2136637275","https://openalex.org/W2136673626","https://openalex.org/W2139241586","https://openalex.org/W2140449315","https://openalex.org/W2144689576","https://openalex.org/W2148182857","https://openalex.org/W2151012090","https://openalex.org/W2151815081","https://openalex.org/W2153005316","https://openalex.org/W2162566359","https://openalex.org/W2171319945","https://openalex.org/W2945792041","https://openalex.org/W4212918185","https://openalex.org/W4247044119","https://openalex.org/W4250622196","https://openalex.org/W4256502601"],"related_works":["https://openalex.org/W1989954799","https://openalex.org/W3145970293","https://openalex.org/W4226020922","https://openalex.org/W2032736436","https://openalex.org/W4402748946","https://openalex.org/W2613841955","https://openalex.org/W2026524777","https://openalex.org/W2503634245","https://openalex.org/W2359729836","https://openalex.org/W2388213615"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Animal":[1],"models":[2],"designed":[3],"to":[4,15,51,141,183,284],"mimic":[5],"certain":[6],"features":[7],"of":[8,19,23,46,55,154,172,195,291,299],"Alzheimer's":[9],"disease":[10],"(AD)":[11],"can":[12],"help":[13],"us":[14],"increase":[16],"our":[17],"understanding":[18],"the":[20,44,47,53,155,166,178,184,200,217,230,236,257,270,275,282],"underlying":[21],"mechanisms":[22],"disease.":[24],"Previous":[25],"studies":[26],"have":[27,281],"revealed":[28,192],"that":[29,165],"long-term":[30],"D-galactose":[31,67,103,109,115],"injection":[32,122],"combined":[33],"with":[34,41,64,102,108,206,274],"ovariectomy":[35,65],"results":[36,191],"in":[37,177,199,216,229,235,256,269,295],"pathophysiologic":[38],"alterations":[39,247,290],"associated":[40,63],"AD.":[42,76],"Thus,":[43],"aim":[45],"present":[48],"study":[49],"was":[50,118,127],"investigate":[52],"effects":[54],"rosmarinic":[56,95,111],"acid":[57,96,112],"(RA)":[58],"administration":[59],"on":[60],"pathological":[61],"changes":[62],"and":[66,110,123,136,145,151,169,213,225,239,248,263,288,306],"injection,":[68],"which":[69],"serve":[70],"as":[71,181],"a":[72,193,296],"two-insult":[73],"model":[74,298],"for":[75,131],"MATERIAL":[77],"AND":[78],"METHODS:":[79],"One":[80],"hundred":[81],"female":[82],"Wistar":[83],"rats":[84,100,106,173],"were":[85,139,158,174,233,254,267],"divided":[86],"into":[87],"five":[88],"equal":[89],"groups:":[90],"control":[91],"(C),":[92],"Sham":[93],"(Sh),":[94],"treated":[97,101,107],"(R),":[98],"ovariectomized":[99,105],"(OD),":[104],"(ODR)":[113],"groups.":[114,187],"(80":[116],"mg/kg/day)":[117,126],"administered":[119],"by":[120,302],"i.p.":[121],"RA":[124,207,240,279],"(50":[125],"given":[128],"via":[129],"gavage":[130],"60":[132],"days.":[133],"Open":[134,161],"field":[135,162],"Y-maze":[137,189],"tests":[138],"used":[140],"assess":[142],"locomotor":[143,167,211],"activity":[144,168,212],"short-term":[146,196],"spatial":[147,197],"memory,":[148],"respectively.":[149],"Biochemical":[150],"histopathological":[152,246],"analyses":[153],"brain":[156,231,292],"tissue":[157,232,293],"performed.":[159],"RESULTS:":[160],"testing":[163],"showed":[164],"exploratory":[170],"behavior":[171],"prominently":[175],"impaired":[176],"OD":[179,201,237,258,276],"group":[180,238,272],"compared":[182,273],"other":[185],"studied":[186],"Similarly,":[188],"test":[190],"decrease":[194],"memory":[198],"rats.":[202],"A":[203],"concomitant":[204],"treatment":[205,241],"significantly":[208],"restored":[209],"altered":[210],"cognitive":[214],"functions":[215],"ODR":[218,271],"group.":[219,259,277],"Lipid":[220],"peroxidation":[221,305],"levels,":[222],"cyclooxygenase-2":[223],"expression":[224],"prostaglandin":[226],"E2":[227],"levels":[228],"higher":[234],"inhibited":[242],"these":[243],"changes.":[244],"AD-like":[245],"amyloid":[249],"b":[250],"peptide":[251],"(Ab)":[252],"depositions":[253,266],"observed":[255,268],"Normal":[260],"cell":[261],"structure":[262],"lower":[264],"Ab":[265],"CONCLUSIONS:":[278],"could":[280],"potential":[283],"prevent":[285],"some":[286],"psychological":[287],"biochemical":[289],"found":[294],"rat":[297],"AD":[300],"probably":[301],"attenuating":[303],"lipid":[304],"inflammatory":[307],"response.":[308]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}