{"id":"https://openalex.org/W2332909178","doi":"https://doi.org/10.1021/ac5039362","title":"MALDI-MS-Based Quantitative Analysis for Ketone Containing Homoserine Lactones in Pseudomonas aeruginosa","display_name":"MALDI-MS-Based Quantitative Analysis for Ketone Containing Homoserine Lactones in Pseudomonas aeruginosa","publication_year":2014,"publication_date":"2014-12-19","ids":{"openalex":"https://openalex.org/W2332909178","doi":"https://doi.org/10.1021/ac5039362","mag":"2332909178","pmid":"https://pubmed.ncbi.nlm.nih.gov/25525717"},"language":"en","primary_location":{"id":"doi:10.1021/ac5039362","doi":"https://doi.org/10.1021/ac5039362","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ac5039362","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072346815","display_name":"Yoon-Woo Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141371507","display_name":"Soongsil University","ror":"https://ror.org/017xnm587","country_code":"KR","type":"education","lineage":["https://openalex.org/I141371507"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yoon-Woo Kim","raw_affiliation_strings":["Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea","institution_ids":["https://openalex.org/I141371507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038998328","display_name":"Changmin Sung","orcid":"https://orcid.org/0000-0001-7318-7353","observed_orcids":["https://orcid.org/0000-0001-7318-7353"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Changmin Sung","raw_affiliation_strings":["School\rof Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School\rof Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Seulee Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141371507","display_name":"Soongsil University","ror":"https://ror.org/017xnm587","country_code":"KR","type":"education","lineage":["https://openalex.org/I141371507"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seulee Lee","raw_affiliation_strings":["Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea","institution_ids":["https://openalex.org/I141371507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089249684","display_name":"Kyoung Jin Kim","orcid":"https://orcid.org/0000-0001-7925-2515","observed_orcids":["https://orcid.org/0000-0001-7925-2515"]},"institutions":[{"id":"https://openalex.org/I141371507","display_name":"Soongsil University","ror":"https://ror.org/017xnm587","country_code":"KR","type":"education","lineage":["https://openalex.org/I141371507"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyoung-Jin Kim","raw_affiliation_strings":["Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea","institution_ids":["https://openalex.org/I141371507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026721642","display_name":"Yung\u2010Hun Yang","orcid":"https://orcid.org/0000-0003-1813-9265","observed_orcids":["https://orcid.org/0000-0003-1813-9265","https://orcid.org/0009-0005-8625-7863"]},"institutions":[{"id":"https://openalex.org/I24062138","display_name":"Konkuk University","ror":"https://ror.org/025h1m602","country_code":"KR","type":"education","lineage":["https://openalex.org/I24062138"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yung-Hun Yang","raw_affiliation_strings":["Department\rof Microbial Engineering, College of Engineering, Konkuk University, Seoul 143-701, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Microbial Engineering, College of Engineering, Konkuk University, Seoul 143-701, Korea","institution_ids":["https://openalex.org/I24062138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052315121","display_name":"Byung\u2010Gee Kim","orcid":"https://orcid.org/0000-0002-3776-1001","observed_orcids":["https://orcid.org/0000-0002-3776-1001"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Byung-Gee Kim","raw_affiliation_strings":["School\rof Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School\rof Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013580761","display_name":"Yoo Kyung Lee","orcid":"https://orcid.org/0000-0002-1271-5738","observed_orcids":["https://orcid.org/0000-0002-1271-5738"]},"institutions":[{"id":"https://openalex.org/I4210093716","display_name":"Korea Polar Research Institute","ror":"https://ror.org/00n14a494","country_code":"KR","type":"facility","lineage":["https://openalex.org/I133437993","https://openalex.org/I4210093716"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yoo Kyung Lee","raw_affiliation_strings":["Arctic Research\rCenter, Korea Polar Research Institute, Incheon 406-840, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arctic Research\rCenter, Korea Polar Research Institute, Incheon 406-840, Korea","institution_ids":["https://openalex.org/I4210093716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109342975","display_name":"Hee Wook Ryu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141371507","display_name":"Soongsil University","ror":"https://ror.org/017xnm587","country_code":"KR","type":"education","lineage":["https://openalex.org/I141371507"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hee Wook Ryu","raw_affiliation_strings":["Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea","institution_ids":["https://openalex.org/I141371507"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011272746","display_name":"Yun\u2010Gon Kim","orcid":"https://orcid.org/0000-0001-7388-2989","observed_orcids":["https://orcid.org/0000-0001-7388-2989"]},"institutions":[{"id":"https://openalex.org/I141371507","display_name":"Soongsil University","ror":"https://ror.org/017xnm587","country_code":"KR","type":"education","lineage":["https://openalex.org/I141371507"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Yun-Gon Kim","raw_affiliation_strings":["Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Chemical Engineering, Soongsil University, Seoul 156-743, Korea","institution_ids":["https://openalex.org/I141371507"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5011272746","https://openalex.org/A5109342975"],"corresponding_institution_ids":["https://openalex.org/I141371507"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.8812,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.71329351,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"87","issue":"2","first_page":"858","last_page":"863"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.7954000234603882,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.7954000234603882,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.17640000581741333,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/n-acyl-homoserine-lactones","display_name":"N-acyl homoserine lactones","score":0.9470000267028809},{"id":"https://openalex.org/keywords/quorum-sensing","display_name":"quorum sensing","score":0.9290000200271606},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa-pao1","display_name":"Pseudomonas aeruginosa PAO1","score":0.9610000252723694},{"id":"https://openalex.org/keywords/girard-s-reagent-t","display_name":"Girard's reagent T","score":0.925000011920929},{"id":"https://openalex.org/keywords/derivatization","display_name":"derivatization","score":0.8510000109672546},{"id":"https://openalex.org/keywords/detection-limit","display_name":"detection limit","score":0.7070000171661377},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.5759999752044678},{"id":"https://openalex.org/keywords/biofilm","display_name":"biofilm","score":0.6990000009536743}],"concepts":[{"id":"https://openalex.org/C118687296","wikidata":"https://www.wikidata.org/wiki/Q905754","display_name":"Quorum sensing","level":4,"score":0.9222146272659302},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8950234651565552},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.7792397737503052},{"id":"https://openalex.org/C2776923573","wikidata":"https://www.wikidata.org/wiki/Q2294884","display_name":"Derivatization","level":3,"score":0.6555907726287842},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.5688382983207703},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.5651154518127441},{"id":"https://openalex.org/C2779840497","wikidata":"https://www.wikidata.org/wiki/Q418214","display_name":"Homoserine","level":5,"score":0.5530154705047607},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.5441856980323792},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5164816379547119},{"id":"https://openalex.org/C2781463711","wikidata":"https://www.wikidata.org/wiki/Q131143","display_name":"Pseudomonas","level":3,"score":0.48715922236442566},{"id":"https://openalex.org/C2781427627","wikidata":"https://www.wikidata.org/wiki/Q410503","display_name":"Pyocyanin","level":5,"score":0.42122164368629456},{"id":"https://openalex.org/C2781090273","wikidata":"https://www.wikidata.org/wiki/Q1623405","display_name":"Virulence factor","level":4,"score":0.41914913058280945},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35474997758865356},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.25496813654899597},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.16409754753112793},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0617561936378479},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002853","descriptor_name":"Chromatography, Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007659","descriptor_name":"Ketones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015107","descriptor_name":"4-Butyrolactone","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D015107","descriptor_name":"4-Butyrolactone","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053038","descriptor_name":"Quorum Sensing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/ac5039362","doi":"https://doi.org/10.1021/ac5039362","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ac5039362","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},{"id":"pmid:25525717","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25525717","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G178352606","display_name":null,"funder_award_id":"PD14010","funder_id":"https://openalex.org/F4320322474","funder_display_name":"Korea Polar Research Institute"},{"id":"https://openalex.org/G8514232376","display_name":null,"funder_award_id":"NRF-2013R1A1A1004998","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"}],"funders":[{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"},{"id":"https://openalex.org/F4320322474","display_name":"Korea Polar Research Institute","ror":"https://ror.org/00n14a494"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1502461125","https://openalex.org/W1555657499","https://openalex.org/W1967221794","https://openalex.org/W1968854207","https://openalex.org/W1975073422","https://openalex.org/W1981704128","https://openalex.org/W1988874714","https://openalex.org/W1998002492","https://openalex.org/W2015718294","https://openalex.org/W2028157318","https://openalex.org/W2030367656","https://openalex.org/W2032173550","https://openalex.org/W2032402343","https://openalex.org/W2038309376","https://openalex.org/W2043539079","https://openalex.org/W2044357500","https://openalex.org/W2050187150","https://openalex.org/W2050492994","https://openalex.org/W2064681842","https://openalex.org/W2065064073","https://openalex.org/W2083761792","https://openalex.org/W2089582851","https://openalex.org/W2098894017","https://openalex.org/W2126922170","https://openalex.org/W2144746095","https://openalex.org/W2148161452","https://openalex.org/W2148688684","https://openalex.org/W2150417163","https://openalex.org/W2153784140","https://openalex.org/W2155439177","https://openalex.org/W2161382818","https://openalex.org/W2161419801","https://openalex.org/W2169391185","https://openalex.org/W2321995885"],"related_works":["https://openalex.org/W2750653061","https://openalex.org/W2367970212","https://openalex.org/W2050187150","https://openalex.org/W1968854207","https://openalex.org/W2535575724","https://openalex.org/W1579938600","https://openalex.org/W2366217003","https://openalex.org/W2090013192","https://openalex.org/W2414483925","https://openalex.org/W4210322610"],"abstract_inverted_index":{"N-Acyl":[0],"homoserine":[1],"lactones":[2],"(AHLs),":[3],"quorum":[4,173],"sensing":[5,174],"molecules":[6,176],"produced":[7],"by":[8,69,129],"Gram-negative":[9],"bacteria,":[10],"are":[11],"used":[12],"as":[13,182],"important":[14],"secondary":[15],"metabolites":[16],"for":[17,31,165],"antibacterial":[18,187],"drug":[19,188],"development":[20],"and":[21,33,62,168,186],"cell-to-cell":[22],"communication.":[23],"Although":[24],"various":[25],"analytical":[26],"techniques":[27],"have":[28,47],"been":[29,48],"developed":[30,58],"detection":[32,134,170],"quantitation":[34,67,139],"of":[35,87,95,118,133,138,172],"AHLs":[36,91,120,147],"from":[37,92,153],"more":[38,149],"complex":[39],"bacterial":[40,96],"culture":[41,158],"media,":[42],"only":[43],"a":[44,59,77],"few":[45],"methods":[46,171],"applied":[49,164],"to":[50,75,125],"AHL":[51,66],"identification":[52],"in":[53,177],"physiological":[54],"samples.":[55],"Here,":[56],"we":[57],"highly":[60],"sensitive":[61,169],"reliable":[63],"MALDI-based":[64],"3-oxo":[65,119,146],"method":[68,161],"employing":[70],"Girard's":[71],"reagent":[72],"T":[73],"(GT)":[74],"produce":[76],"permanent":[78],"cationic":[79],"charge":[80],"state":[81],"[M](+)":[82],"at":[83],"the":[84,93,101,131,144,154],"ketone":[85],"group":[86],"AHLs.":[88],"After":[89],"extracting":[90],"supernatant":[94],"cultures":[97],"using":[98],"ethyl":[99],"acetate,":[100],"extracts":[102],"were":[103],"subsequently":[104],"derivatized":[105],"with":[106],"GT":[107],"without":[108],"any":[109],"additional":[110],"purification":[111],"or":[112],"desalting":[113],"steps.":[114],"The":[115],"chemical":[116],"derivatization":[117],"dramatically":[121],"enhanced":[122],"sensitivity":[123],"(up":[124],"60":[126],"000":[127],"times)":[128],"lowering":[130],"limit":[132],"(LOD,":[135],"\u223c0.5":[136],"fmol)/limit":[137],"(LOQ,":[140],"\u223c2.5":[141],"fmol).":[142],"Additionally,":[143],"GT-derivatized":[145],"allowed":[148],"accurate":[150],"quantitative":[151],"analysis":[152],"Pseudomonas":[155],"aeruginosa":[156],"PAO1":[157],"supernatants.":[159],"This":[160],"may":[162],"be":[163],"developing":[166],"high-throughput":[167],"signal":[175],"biofilm-related":[178],"clinical":[179],"applications":[180],"such":[181],"virulence":[183],"factor":[184],"characterization":[185],"development.":[189]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":8},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}