{"id":"https://openalex.org/W2332719085","doi":"https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1248","title":"16\u00b1 OHE Exacerbates Pulmonary Arterial Hypertension In Humans And Mice With BMPR2 Mutations","display_name":"16\u00b1 OHE Exacerbates Pulmonary Arterial Hypertension In Humans And Mice With BMPR2 Mutations","publication_year":2012,"publication_date":"2012-05-01","ids":{"openalex":"https://openalex.org/W2332719085","doi":"https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1248","mag":"2332719085"},"language":"en","primary_location":{"id":"doi:10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1248","doi":"https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1248","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1248","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"A29. PATHOGENESIS OF PULMONARY HYPERTENSION","raw_type":"proceedings-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030467856","display_name":"Eric D. Austin","orcid":"https://orcid.org/0000-0002-1709-9022","observed_orcids":["https://orcid.org/0000-0002-1709-9022"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eric D. Austin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056044508","display_name":"Anna Ryan Hemnes","orcid":"https://orcid.org/0000-0002-2755-5845","observed_orcids":["https://orcid.org/0000-0002-2755-5845"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Hemnes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017870559","display_name":"Joshua P. Fessel","orcid":"https://orcid.org/0000-0003-0797-7693","observed_orcids":["https://orcid.org/0000-0003-0797-7693"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joshua P. Fessel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058773601","display_name":"Santhi Gladson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Santhi Gladson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109834846","display_name":"Linda J. Robinson","orcid":"https://orcid.org/0000-0002-5089-5362","observed_orcids":["https://orcid.org/0000-0002-5089-5362"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Linda Robinson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111625927","display_name":"Tom Blackwell","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tom Blackwell","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051910732","display_name":"Lora K. Hedges","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lora Hedges","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105415221","display_name":"Lisa A Wheeler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lisa Wheeler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111552866","display_name":"Kirk B. Lane","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kirk Lane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065762639","display_name":"James E. Loyd","orcid":"https://orcid.org/0000-0002-5042-7390","observed_orcids":["https://orcid.org/0000-0002-5042-7390"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James E. Loyd","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5042419219","display_name":"James D. West","orcid":"https://orcid.org/0000-0002-6004-0202","observed_orcids":["https://orcid.org/0000-0002-6004-0202"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James D. West","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"A1248","last_page":"A1248"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12199","display_name":"Vascular Anomalies and Treatments","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-arterial-hypertension","display_name":"pulmonary arterial hypertension","score":0.9340000152587891},{"id":"https://openalex.org/keywords/bmpr2-mutations","display_name":"BMPR2 mutations","score":0.9769999980926514},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.6039999723434448},{"id":"https://openalex.org/keywords/pulmonary-hypertension-pathogenesis","display_name":"pulmonary hypertension pathogenesis","score":0.49000000953674316}],"concepts":[{"id":"https://openalex.org/C73834784","wikidata":"https://www.wikidata.org/wiki/Q17849752","display_name":"BMPR2","level":4,"score":0.8943086862564087},{"id":"https://openalex.org/C2780930700","wikidata":"https://www.wikidata.org/wiki/Q1128595","display_name":"Pulmonary hypertension","level":2,"score":0.4765370786190033},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4610745906829834},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4318958520889282},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.41609349846839905},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37395399808883667},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20520582795143127},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20328214764595032},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10203838348388672},{"id":"https://openalex.org/C31507581","wikidata":"https://www.wikidata.org/wiki/Q425383","display_name":"Bone morphogenetic protein","level":3,"score":0.06432470679283142}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1248","doi":"https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1248","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1248","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"A29. PATHOGENESIS OF PULMONARY HYPERTENSION","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3044597479","https://openalex.org/W2319386053","https://openalex.org/W2125960102","https://openalex.org/W2335203048","https://openalex.org/W2518252291","https://openalex.org/W2322546105","https://openalex.org/W2003155673","https://openalex.org/W4225312529","https://openalex.org/W4400462122","https://openalex.org/W2069061837"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}