{"id":"https://openalex.org/W2332452733","doi":"https://doi.org/10.1097/qai.0000000000000246","title":"High Medication Adherence During Periconception Periods Among HIV-1\u2013Uninfected Women Participating in a Clinical Trial of Antiretroviral Pre-exposure Prophylaxis","display_name":"High Medication Adherence During Periconception Periods Among HIV-1\u2013Uninfected Women Participating in a Clinical Trial of Antiretroviral Pre-exposure Prophylaxis","publication_year":2014,"publication_date":"2014-06-02","ids":{"openalex":"https://openalex.org/W2332452733","doi":"https://doi.org/10.1097/qai.0000000000000246","mag":"2332452733","pmid":"https://pubmed.ncbi.nlm.nih.gov/25118795","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4149628"},"language":"en","primary_location":{"id":"doi:10.1097/qai.0000000000000246","doi":"https://doi.org/10.1097/qai.0000000000000246","is_oa":true,"landing_page_url":"https://doi.org/10.1097/qai.0000000000000246","pdf_url":null,"source":{"id":"https://openalex.org/S157460402","display_name":"JAIDS Journal of Acquired Immune Deficiency Syndromes","issn_l":"1525-4135","issn":["1525-4135","1944-7884"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAIDS Journal of Acquired Immune Deficiency Syndromes","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1097/qai.0000000000000246","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079821443","display_name":"Lynn T. Matthews","orcid":"https://orcid.org/0000-0001-6167-6328","observed_orcids":["https://orcid.org/0000-0001-6167-6328"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I2841861","display_name":"Kenya Medical Research Institute","ror":"https://ror.org/04r1cxt79","country_code":"KE","type":"facility","lineage":["https://openalex.org/I2841861"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["KE","US"],"is_corresponding":true,"raw_author_name":"Lynn T. Matthews","raw_affiliation_strings":["*Division of Infectious Disease and Center for Global Health, Massachusetts General Hospital, Boston, MA; \u2020Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, MA; \u2021Department of Global Health, University of Washington, Seattle, WA; \u00a7Kenya Medical Research Institute, Nairobi, Kenya; \u2016Department of Obstetrics, Gynecology and Reproductive Sciences, Bixby Center for Global Reproductive Health, University of California San Francisco, San Francisco, CA; \u00b6Department of Medicine, Johns Hopkins University, Baltimore, MD; #Department of Medicine, University of Washington, Seattle, WA; and **Department of Epidemiology, University of Washington, Seattle, WA","Division of Infectious Disease and Center for Global Health, Massachusetts General Hospital, Boston, MA","Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Division of Infectious Disease and Center for Global Health, Massachusetts General Hospital, Boston, MA; \u2020Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, MA; \u2021Department of Global Health, University of Washington, Seattle, WA; \u00a7Kenya Medical Research Institute, Nairobi, Kenya; \u2016Department of Obstetrics, Gynecology and Reproductive Sciences, Bixby Center for Global Reproductive Health, University of California San Francisco, San Francisco, CA; \u00b6Department of Medicine, Johns Hopkins University, Baltimore, MD; #Department of Medicine, University of Washington, Seattle, WA; and **Department of Epidemiology, University of Washington, Seattle, WA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I145311948","https://openalex.org/I180670191","https://openalex.org/I201448701","https://openalex.org/I2799853436","https://openalex.org/I2841861","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Division of Infectious Disease and Center for Global Health, Massachusetts General Hospital, Boston, MA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, MA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062258141","display_name":"Renee A. Heffron","orcid":"https://orcid.org/0000-0001-6039-0352","observed_orcids":["https://orcid.org/0000-0001-6039-0352"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Renee Heffron","raw_affiliation_strings":["Department of Global Health, University of Washington, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Global Health, University of Washington, Seattle, WA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035859750","display_name":"Nelly Mugo","orcid":"https://orcid.org/0000-0002-2347-006X","observed_orcids":["https://orcid.org/0000-0002-2347-006X"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I2841861","display_name":"Kenya Medical Research Institute","ror":"https://ror.org/04r1cxt79","country_code":"KE","type":"facility","lineage":["https://openalex.org/I2841861"]}],"countries":["KE","US"],"is_corresponding":false,"raw_author_name":"Nelly R. Mugo","raw_affiliation_strings":["Department of Global Health, University of Washington, Seattle, WA","Kenya Medical Research Institute, Nairobi, Kenya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Global Health, University of Washington, Seattle, WA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Kenya Medical Research Institute, Nairobi, Kenya","institution_ids":["https://openalex.org/I2841861"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011315383","display_name":"Craig R. Cohen","orcid":"https://orcid.org/0000-0001-8654-6634","observed_orcids":["https://orcid.org/0000-0001-8654-6634"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Craig R. Cohen","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Bixby Center for Global Reproductive Health, University of California San Francisco, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Bixby Center for Global Reproductive Health, University of California San Francisco, San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053567182","display_name":"Craig W. Hendrix","orcid":"https://orcid.org/0000-0002-5696-8665","observed_orcids":["https://orcid.org/0000-0002-5696-8665"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Craig W. Hendrix","raw_affiliation_strings":["Department of Medicine, Johns Hopkins University, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Johns Hopkins University, Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090773831","display_name":"Connie Celum","orcid":"https://orcid.org/0000-0002-8813-3419","observed_orcids":["https://orcid.org/0000-0002-8813-3419"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Connie Celum","raw_affiliation_strings":["Department of Epidemiology, University of Washington, Seattle, WA","Department of Global Health, University of Washington, Seattle, WA","Department of Medicine, University of Washington, Seattle, WA; and","Department of Medicine, University of Washington, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, University of Washington, Seattle, WA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Global Health, University of Washington, Seattle, WA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Medicine, University of Washington, Seattle, WA; and","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Medicine, University of Washington, Seattle, WA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073389592","display_name":"David R. Bangsberg","orcid":"https://orcid.org/0000-0002-6352-8908","observed_orcids":["https://orcid.org/0000-0002-6352-8908"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David R. Bangsberg","raw_affiliation_strings":["Division of Infectious Disease and Center for Global Health, Massachusetts General Hospital, Boston, MA","Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Disease and Center for Global Health, Massachusetts General Hospital, Boston, MA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, MA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064486492","display_name":"Jared M. Baeten","orcid":"https://orcid.org/0000-0001-8242-8438","observed_orcids":["https://orcid.org/0000-0001-8242-8438"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jared M. Baeten","raw_affiliation_strings":["","Department of Epidemiology, University of Washington, Seattle, WA","Department of Global Health, University of Washington, Seattle, WA","Department of Medicine, University of Washington, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology, University of Washington, Seattle, WA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Global Health, University of Washington, Seattle, WA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Medicine, University of Washington, Seattle, WA","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5064486492","https://openalex.org/A5073389592","https://openalex.org/A5079821443","https://openalex.org/A5090773831"],"corresponding_institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I145311948","https://openalex.org/I180670191","https://openalex.org/I201448701","https://openalex.org/I2799853436","https://openalex.org/I2841861","https://openalex.org/I4210087915"],"apc_list":null,"apc_paid":null,"fwci":5.1367,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.96192762,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"67","issue":"1","first_page":"91","last_page":"97"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10600","display_name":"Reproductive Health and Contraception","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pre-exposure-prophylaxis","display_name":"pre-exposure prophylaxis","score":0.8970000147819519},{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.6010000109672546},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.8309999704360962},{"id":"https://openalex.org/keywords/periconception-period","display_name":"periconception period","score":0.8100000023841858},{"id":"https://openalex.org/keywords/safer-conception","display_name":"safer conception","score":0.875},{"id":"https://openalex.org/keywords/hiv-serodiscordant-couples","display_name":"HIV serodiscordant couples","score":0.8389999866485596},{"id":"https://openalex.org/keywords/pregnancy-incidence","display_name":"pregnancy incidence","score":0.6320000290870667},{"id":"https://openalex.org/keywords/tenofovir","display_name":"tenofovir","score":0.9509999752044678},{"id":"https://openalex.org/keywords/contraception","display_name":"contraception","score":0.5410000085830688},{"id":"https://openalex.org/keywords/pill-count","display_name":"pill count","score":0.5920000076293945},{"id":"https://openalex.org/keywords/plasma-drug-concentration","display_name":"plasma drug concentration","score":0.7689999938011169},{"id":"https://openalex.org/keywords/unprotected-sex","display_name":"unprotected sex","score":0.5870000123977661},{"id":"https://openalex.org/keywords/african-women","display_name":"African women","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9113801121711731},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.7684742212295532},{"id":"https://openalex.org/C81603835","wikidata":"https://www.wikidata.org/wiki/Q3457430","display_name":"Pill","level":2,"score":0.645885705947876},{"id":"https://openalex.org/C2780500702","wikidata":"https://www.wikidata.org/wiki/Q7455026","display_name":"Serodiscordant","level":5,"score":0.6185961365699768},{"id":"https://openalex.org/C2779496540","wikidata":"https://www.wikidata.org/wiki/Q7239230","display_name":"Pre-exposure prophylaxis","level":5,"score":0.6062442064285278},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5323636531829834},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5121881365776062},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5004177093505859},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4764323830604553},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.39096418023109436},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.3209422826766968},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.27700597047805786},{"id":"https://openalex.org/C2776939746","wikidata":"https://www.wikidata.org/wiki/Q853451","display_name":"Men who have sex with men","level":4,"score":0.18401265144348145},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.1532759666442871},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.09456166625022888},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.08536797761917114},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C2776983459","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis","level":3,"score":0.0},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000068698","descriptor_name":"Tenofovir","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000225","descriptor_name":"Adenine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000225","descriptor_name":"Adenine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D000225","descriptor_name":"Adenine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005306","descriptor_name":"Fertilization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007630","descriptor_name":"Kenya","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014454","descriptor_name":"Uganda","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D055118","descriptor_name":"Medication Adherence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063065","descriptor_name":"Organophosphonates","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D063065","descriptor_name":"Organophosphonates","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D065129","descriptor_name":"Pre-Exposure Prophylaxis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D065129","descriptor_name":"Pre-Exposure Prophylaxis","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1097/qai.0000000000000246","doi":"https://doi.org/10.1097/qai.0000000000000246","is_oa":true,"landing_page_url":"https://doi.org/10.1097/qai.0000000000000246","pdf_url":null,"source":{"id":"https://openalex.org/S157460402","display_name":"JAIDS Journal of Acquired Immune Deficiency Syndromes","issn_l":"1525-4135","issn":["1525-4135","1944-7884"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAIDS Journal of Acquired Immune Deficiency Syndromes","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3123836","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4149628","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4149628","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4149628","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Acquir Immune Defic Syndr","raw_type":"Text"},{"id":"pmid:25118795","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25118795","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of acquired immune deficiency syndromes (1999)","raw_type":"Clinical Trial, Phase III"},{"id":"pmh:oai:pdxscholar.library.pdx.edu:sph_facpub-1011","doi":null,"is_oa":true,"landing_page_url":"https://pdxscholar.library.pdx.edu/sph_facpub/12","pdf_url":null,"source":{"id":"https://openalex.org/S4377196300","display_name":"PDXScholar  (Portland State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I126345244","host_organization_name":"Portland State University","host_organization_lineage":["https://openalex.org/I126345244"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"OHSU-PSU School of Public Health Faculty Publications and Presentations","raw_type":"text"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt0vk7j1zv","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/0vk7j1zv","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:qt0vk7j1zv","doi":null,"is_oa":false,"landing_page_url":"http://www.escholarship.org/uc/item/0vk7j1zv","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cohen, Craig; Matthews, LT; Heffron, R; Mugo, NR; Hendrix, CW; Celum, C; \u00c2\u00a0et al.(2014). High medication adherence during periconception periods among HIV-1-uninfected women participating in a clinical trial of antiretroviral pre-exposure prophylaxis. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0vk7j1zv","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1097/qai.0000000000000246","doi":"https://doi.org/10.1097/qai.0000000000000246","is_oa":true,"landing_page_url":"https://doi.org/10.1097/qai.0000000000000246","pdf_url":null,"source":{"id":"https://openalex.org/S157460402","display_name":"JAIDS Journal of Acquired Immune Deficiency Syndromes","issn_l":"1525-4135","issn":["1525-4135","1944-7884"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAIDS Journal of Acquired Immune Deficiency Syndromes","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1084389469","display_name":"Delivery of integrated PrEP and ART for HIV prevention for couples in Kenya","funder_award_id":"R01MH095507","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G1576456798","display_name":"Antiretroviral periconception HIV prevention for HIV discordant couples","funder_award_id":"K99HD076679","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G5359131545","display_name":"Hormonal contraception, pre-exposure prophylaxis, and HIV-1 protection","funder_award_id":"R21HD074439","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G5472675340","display_name":"Periconception HIV risk reduction for HIV-discordant couples in Uganda","funder_award_id":"K23MH095655","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6419530638","display_name":"Mentoring Patient Oriented Adherence Research in Uganda","funder_award_id":"K24MH087227","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6690469706","display_name":null,"funder_award_id":"OOP47674","funder_id":"https://openalex.org/F4320306137","funder_display_name":"Bill and Melinda Gates Foundation"},{"id":"https://openalex.org/G9000895751","display_name":"Center for AIDS Prevention Studies (CAPS)","funder_award_id":"P30MH062246","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320306137","display_name":"Bill and Melinda Gates Foundation","ror":"https://ror.org/0456r8d26"},{"id":"https://openalex.org/F4320308573","display_name":"Gilead Sciences","ror":"https://ror.org/056546b03"},{"id":"https://openalex.org/F4320310094","display_name":"University of Washington","ror":"https://ror.org/00cvxb145"},{"id":"https://openalex.org/F4320310145","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1964519673","https://openalex.org/W1965890870","https://openalex.org/W1986705681","https://openalex.org/W2015176800","https://openalex.org/W2015855279","https://openalex.org/W2033156690","https://openalex.org/W2038662816","https://openalex.org/W2040386767","https://openalex.org/W2040552615","https://openalex.org/W2043472980","https://openalex.org/W2046951262","https://openalex.org/W2052483152","https://openalex.org/W2064166461","https://openalex.org/W2077318378","https://openalex.org/W2096511249","https://openalex.org/W2100756872","https://openalex.org/W2101116561","https://openalex.org/W2103920597","https://openalex.org/W2111938650","https://openalex.org/W2112326059","https://openalex.org/W2115308626","https://openalex.org/W2116605213","https://openalex.org/W2117057469","https://openalex.org/W2124850699","https://openalex.org/W2124935942","https://openalex.org/W2127175235","https://openalex.org/W2131957317","https://openalex.org/W2136527705","https://openalex.org/W2144198686","https://openalex.org/W2146634980","https://openalex.org/W2153941399","https://openalex.org/W2154854455","https://openalex.org/W2156896622","https://openalex.org/W2162226934","https://openalex.org/W2163974471","https://openalex.org/W2168251450","https://openalex.org/W2170428661","https://openalex.org/W2170820745","https://openalex.org/W2171820290","https://openalex.org/W2735787759","https://openalex.org/W4300283808"],"related_works":["https://openalex.org/W7100372341","https://openalex.org/W4396956624","https://openalex.org/W4405518072","https://openalex.org/W3042133875","https://openalex.org/W4321004198","https://openalex.org/W2111938650","https://openalex.org/W2154854455","https://openalex.org/W4405630436","https://openalex.org/W4416237811","https://openalex.org/W4387081588"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Pre-exposure":[1],"prophylaxis":[2],"(PrEP)":[3],"may":[4,23,230],"be":[5,231],"an":[6,115,232],"important":[7],"safer":[8,30,236],"conception":[9,31,237],"strategy":[10,238],"for":[11,71,151,191,239],"HIV-1-uninfected":[12,45,240],"women":[13,46,136,192,241],"with":[14,125,145,166,242],"HIV-1-infected":[15],"partners.":[16,244],"Understanding":[17],"medication":[18,43,225],"adherence":[19,40,68,150,160,188],"in":[20,48,159,161,175],"this":[21,203],"population":[22],"inform":[24],"whether":[25],"PrEP":[26,54,229],"is":[27],"a":[28,49,86],"feasible":[29,235],"strategy.":[32],"METHODS:":[33],"We":[34],"evaluated":[35],"predictors":[36],"of":[37,53,79,88,128,141,153,179,206],"pregnancy":[38,72,102,138,182,197,208,222],"and":[39,67,69,119,156,194,234],"to":[41,93,217],"study":[42,75,154],"among":[44,55],"enrolled":[47],"randomized":[50],"placebo-controlled":[51],"trial":[52,205],"African":[56],"HIV-1-serodiscordant":[57,243],"couples.":[58],"Participants":[59],"were":[60,82,123],"counseled":[61],"on":[62],"HIV-1":[63],"risk":[64],"reduction,":[65],"contraception,":[66,113],"tested":[70],"at":[73,85,146,177],"monthly":[74],"visits.":[76],"Pill":[77],"counts":[78,133],"dispensed":[80],"drug":[81,96],"performed":[83],"and,":[84],"subset":[87],"visits,":[89],"plasma":[90,176],"was":[91,104,173,183,189,210],"collected":[92],"measure":[94],"active":[95],"concentration.":[97],"RESULTS:":[98],"Among":[99],"1785":[100],"women,":[101],"incidence":[103,209],"10.2":[105],"per":[106,212],"100":[107],"person-years.":[108],"Younger":[109],"age,":[110],"not":[111,195],"using":[112],"having":[114],"additional":[116],"sexual":[117],"partner,":[118],"reporting":[120],"unprotected":[121],"sex":[122],"associated":[124],"increased":[126],"likelihood":[127],"pregnancy.":[129],"Monthly":[130],"clinic":[131],"pill":[132,149],"estimated":[134],"that":[135,228],"experiencing":[137,193,196,221],"took":[139],"97%":[140],"prescribed":[142],"doses":[143],"overall,":[144],"least":[147],"80%":[148],"98%":[152],"months,":[155],"no":[157],"difference":[158],"the":[162],"periconception":[163],"period":[164],"compared":[165],"previous":[167],"periods":[168],"(P":[169,198],"=":[170],"0.98).":[171],"Tenofovir":[172],"detected":[174],"71%":[178],"visits":[180],"where":[181],"discovered.":[184],"By":[185],"multiple":[186],"measures,":[187],"similar":[190],"\u2265":[199],"0.1).":[200],"CONCLUSIONS:":[201],"In":[202],"clinical":[204],"PrEP,":[207],"10%":[211],"year":[213],"despite":[214],"excellent":[215],"access":[216],"effective":[218],"contraception.":[219],"Women":[220],"had":[223],"high":[224],"adherence,":[226],"suggesting":[227],"acceptable":[233]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}